Patents by Inventor Sean A. Daugherty

Sean A. Daugherty has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7807454
    Abstract: A microfluidic device may employ one or more sorting stations for separating target species from other species in a sample. The separation is driven by magnetophoresis. A sorting station generally includes separate buffer and sample streams. A magnetic field gradient applied to the sorting station deflects the flow path of magnetic particles (which selectively label the target species) from a sample stream into a buffer stream. The buffer stream leaving the sorting station is used to detect or further process purified target species labeled with the magnetic particles.
    Type: Grant
    Filed: October 18, 2006
    Date of Patent: October 5, 2010
    Assignee: The Regents of the University of California
    Inventors: Sang-Hyun Oh, Amarendra Kumar Singh, Yanting Zhang, Dharmakirthi Nawarathna, Unyoung Kim, Patrick Sean Daugherty, Hyongsok Soh, Brian Scott Ferguson
  • Publication number: 20100189760
    Abstract: The present invention provides synthetic cell platforms. The synthetic cell platforms can be used for culturing cells in vitro. The synthetic cell platforms can also be implanted together with bound cells into an individual. The present invention provides methods of using the platforms to provide cells or progeny of such cells for use in various applications, including clinical applications; and methods of use of the platforms to introduce cells into an individual.
    Type: Application
    Filed: March 21, 2008
    Publication date: July 29, 2010
    Inventors: David V. Schaffer, Kevin Edward Healy, Lauren Little, Patrick Sean Daugherty
  • Publication number: 20100173349
    Abstract: The present invention provides compositions including peptide display scaffolds that present at least one candidate peptide and at least one detectable moiety in at least one of the N-terminal and C-terminal candidate peptide presenting domains that when expressed in a cell are accessible at a surface of the cell outermembrane. In addition, the present invention also provides kits and methods for screening a library of cells presenting the candidate peptides in peptide display scaffolds to identify a ligand for an enzyme.
    Type: Application
    Filed: December 23, 2009
    Publication date: July 8, 2010
    Inventors: Patrick Sean Daugherty, Kevin Todd Boulware
  • Patent number: 7666817
    Abstract: The present invention provides compositions including peptide display scaffolds that present at least one candidate peptide and at least one detectable moiety in at least one of the N-terminal and C-terminal candidate peptide presenting domains that when expressed in a cell are accessible at a surface of the cell outermembrane. In addition, the present invention also provides kits and methods for screening a library of cells presenting the candidate peptides in peptide display scaffolds to identify a ligand for an enzyme.
    Type: Grant
    Filed: August 30, 2006
    Date of Patent: February 23, 2010
    Assignee: The Regents of the University of California
    Inventors: Patrick Sean Daugherty, Kevin T. Boulware
  • Publication number: 20080124779
    Abstract: A microfluidic device may employ one or more sorting stations for separating target species from other species in a sample. The separation is driven by magnetophoresis. A sorting station generally includes separate buffer and sample streams. A magnetic field gradient applied to the sorting station deflects the flow path of magnetic particles (which selectively label the target species) from a sample stream into a buffer stream. The buffer stream leaving the sorting station is used to detect or further process purified target species labeled with the magnetic particles.
    Type: Application
    Filed: October 18, 2006
    Publication date: May 29, 2008
    Inventors: Sang-Hyun Oh, Amarendra Kumar Singh, Yanting Zhang, Dharmakirthi Nawarathna, Unyoung Kim, Patrick Sean Daugherty, Hyongsok Soh, Brian Scott Ferguson