Abstract: An information collection unit collects information indicating a driving operation of a vehicle by a driver and a state of the vehicle changed by the driving operation, and outputs, among the collected information, information in a period from a start point at which a driving operation contributing to stop of the vehicle is performed to a stop start point in a stop state where a stop time of the vehicle continues for a predetermined time or more, as driving operation information. A state estimation unit acquires driver state information indicating a state of the driver from a learned learner on which machine learning has been performed so as to output the driver state information when the driving operation information is input, by inputting the driving operation information output from the information collection unit to the learner and performing arithmetic processing of the learner.

Abstract: A multi-branch fixed offshore photovoltaic (PV) structure with automatic pitch adjustment includes a fixed base, a multi-branch integrated tower, and a PV device. The fixed base includes an upper section, a middle section and a lower section arranged in the seabed. The upper section is above the sea level and connected to the multi-branch integrated tower. The multi-branch integrated tower includes a main tower body and multiple pitch-regulating frames rotatably connected to the main tower body. The main tower body is provided with a control and energy storage system to drive the pitch-regulating frames to rotate. The PV device is fixed to the pitch-regulating frames. The main body is provided with a sunlight monitoring system to monitor solar orientation and inclination angle of a sunlight relative to the PV device. The sunlight monitoring system is connected to the control and energy storage system.

Abstract: A measurement and reconstruction method for a turbine blade strain field of with integrates an imaging technology and an infrared photoelectric measurement technology. The imaging technology is mainly responsible for the measurement of the strain field on a target blade surface, so as to use a digital image processing technology to obtain blade strain field data. The infrared photoelectric measurement technology is mainly aimed at the strain at blade edges, which uses temperature difference between the blade edges and blade gaps to perform strain measurement. Measurement results of the two modes are finally converted into blade strain parameters, thereby reconstructing the target blade strain field based on host computer software.

Abstract: An siRNA capable of inhibiting expression of apolipoprotein C3(APOC3) gene, comprising a sense strand and an antisense strand; the sense strand and the antisense strand respectively comprise a nucleotide sequence I and a nucleotide sequence II consisting of 19 modified or unmodified nucleotides, the nucleotide sequence I and the nucleotide sequence II are at least partially reversely complementary to form a double-stranded region, and the nucleotide sequence II is at least partially reversely complementary to a nucleotide sequence in an mRNA expressed by APOC3 gene; in a direction from 5? end to 3? end, at least one of the 3rd to 6th nucleotides of the nucleotide sequence II is a stabilizing modified nucleotide. The siRNA and a pharmaceutical composition and an siRNA conjugate containing same can effectively treat and/or prevent diseases or disorders related to expression of APOC3 gene, and have a significantly reduced off-target effect.

Abstract: A double-stranded oligonucleotide capable of regulating the expression level of a target gene includes a sense strand and an antisense strand. The sense strand and the antisense strand each includes nucleotide sequence I or nucleotide sequence II consisting of 19 modified or unmodified nucleotides, the nucleotide sequence I and the nucleotide sequence II are at least partially reverse complementary to form a double-stranded region, and the nucleotide sequence II is at least partially reverse complementary to a nucleotide sequence in an mRNA expressed by the target gene; and according to the direction from the 5? end to the 3? end, at least one of the 3rd to 6th nucleotides of the nucleotide sequence II is a stabilizing modified nucleotide, and none of the nucleotides other than the 3rd to 9th nucleotides in the nucleotide sequence II are stabilizing modified nucleotides.

Abstract: Provided are an siRNA for inhibiting expression of a Hepatitis B virus gene, and a pharmaceutical composition and conjugate containing the siRNA. Each nucleotide in the siRNA is an independently modified or unmodified nucleotide; the siRNA comprises a sense strand and an antisense strand; the sense strand comprises a nucleotide sequence A; the length of the nucleotide sequence A is the same as that of a nucleotide sequence as shown in SEQ ID NO: 1, and the number of the nucleotide differences is not more than three; the antisense strand comprises a nucleotide sequence B; and the length of the nucleotide sequence B is the same as that of a nucleotide sequence as shown in SEQ ID NO: 2, and number of nucleotide differences is not more than three.

Abstract: Provided are a siRNA for inhibiting the expression of hepatitis B virus gene, and a pharmaceutical composition and conjugate containing the siRNA. Each nucleotide in the siRNA is independently a modified nucleotide. The siRNA comprises a sense strand and an antisense strand. The sense strand of the siRNA comprises a nucleotide sequence 1 having the same length and no more than three nucleotides different from the nucleotide sequence shown in SEQ ID NO: 155, and the antisense strand of the siRNA comprises a nucleotide sequence 2 having the same length and no more than three nucleotides different from the nucleotide sequence shown in SEQ ID NO: 156.

Abstract: A display panel and a display apparatus. The display panel includes: a display area, the display area including a first arrangement area and a second arrangement area disposed in a row direction, a gate driver on array located in the first arrangement area; and a substrate located in the second arrangement area, a light-emitting element located at a side of the substrate, and a pixel circuit connected correspondingly with the light-emitting element, in which an orthographic projection of the light-emitting element on the substrate at least partially does not overlap an orthographic projection of the pixel circuit on the substrate.

Abstract: A mobile charging apparatus can be detachably assembled to a wearable apparatus body, so as to be assembled and fitted to the wearable apparatus body for charging when the wearable apparatus body needs to be charged, and to be separated from the wearable apparatus body when the wearable apparatus body does not need to be charged.

Abstract: A picture prediction method is provided, which includes: obtaining initial motion information of a current picture block; determining, based on a matching cost criterion, that positions of a pair of reference blocks are a position of a target forward reference block of the current picture block and a position of a target backward reference block of the current picture block, where positions of each pair of reference blocks include a position of a forward reference block and a position of a backward reference block; and for the positions of each pair of reference blocks, a first position offset and a second position offset are in a mirror relationship; and obtaining a predicted value of a pixel value of the current picture block based on a pixel value of the target forward reference block and a pixel value of the target backward reference block.

Abstract: The present invention relates to the field of video image processing, and provides a filtering method and an apparatus, to resolve a problem that subjective quality and objective quality of an image deteriorate because filtering processing cannot be performed on internal blocks of a non-translational motion prediction unit.

Abstract: Methods, computer program products, and/or systems are provided that perform the following operations: identifying a first workload being processed by a first plurality of sites in a cluster; identifying, from the first plurality of sites: (i) a first site as a primary site for the first workload, and (ii) one or more secondary sites for the first workload; identifying a communication link issue between the first site and at least one of the one or more secondary sites; splitting the cluster into sub-clusters based, at least in part, on the communication link issue, wherein the first site is included in a first sub-cluster of the sub-clusters and the at least one of the one or more secondary sites is included in a sub-cluster of the sub-clusters that is different from the first sub-cluster; and instructing the first sub-cluster to locally process the first workload.

Abstract: Provided are a manned pole-climbing work platform and a pole-gripping mechanism thereof. The pole-gripping mechanism includes an arm and a distal pole-gripping mechanical hand. The distal pole-gripping mechanical hand includes a front jaw, a rear jaw, a forward-threaded rod, a reverse-threaded rod and a preloader. The front jaw and the rear jaw are articulated with the arm through pivots. The preloader is configured to drive the forward-threaded rod and the reverse-threaded rod to rotate synchronously. The forward-threaded rod and the front jaw are articulated with each other through a front thrust-nut composite pivot. The reverse-threaded rod and the rear jaw are articulated with each other through a rear thrust-nut composite pivot. The front jaw and the rear jaw are openable or closeable relative to each other.

Abstract: A calibration method and a tuning method for an on-chip differential active RC filter are provided. The calibration method comprises: obtaining zero-crossing time of a differential signal outputted by a single-pole point real number filter by analyzing the single-pole point real number filter; setting a reference clock period according to the relationship between the zero-crossing time and the bandwidth of the single-pole point real number filter, and setting a calibration working time sequence according to the reference clock period; and scanning an RC configuration of an RC array according to the calibration working time sequence to realize calibration of the RC array.

Abstract: An siRNA which inhibits kininogen (KNG) gene expression, a pharmaceutical composition containing the siRNA, and an siRNA conjugate. Each nucleotide in the siRNA is independently a modified or unmodified nucleotide. The siRNA contains a sense strand and an antisense strand. The sense strand contains nucleotide sequence I, nucleotide sequence I having the same length as the nucleotide sequence shown in SEQ ID NO: 1, with no more than three nucleotide differences. The antisense strand contains nucleotide sequence II, nucleotide sequence II having the same length as the nucleotide sequence shown in SEQ ID NO: 2, with no more than three nucleotide differences. The siRNA, the pharmaceutical composition thereof and the siRNA conjugate can effectively treat and/or prevent septicemia.

Abstract: Provided are an siRNA which inhibits purine nucleoside phosphorylase (PNP) gene expression, a pharmaceutical composition comprising the siRNA, and an siRNA conjugate, capable of effectively treating and/or preventing abnormal uric acid metabolism, or diseases or physiological conditions caused by abnormal uric acid metabolism. Each nucleotide in the siRNA is independently a modified or unmodified nucleotide.

Abstract: Embodiments of the present invention disclose a magnetic resonance system, a magnetic resonance image correction method, and a magnetic resonance imaging method.

Abstract: An autonomous cleaning device and a noise reduction air duct device are provided for autonomous cleaning device. The autonomous cleaning device includes a body and a motor arranged on the body, and the noise reduction air duct device is mounted on the body. The noise reduction air duct device includes an upper housing, a lower housing and a support noise reduction structure made of elastic material. The lower housing and the upper housing enclose to form an air duct, an air inlet is arranged at a position of the air duct corresponding to the motor, and an air outlet is arranged on a side of the air duct away from the air inlet; the support noise reduction structure has a first end fixed on the lower housing, and a second end abutting against a lower surface of the upper housing.

Abstract: Provided is a siRNA for inhibiting HBV gene expression, including a sense strand and an antisense strand. The sense strand includes a nucleotide sequence 1, and the antisense strand includes a nucleotide sequence 2; the nucleotide sequence 1 and the nucleotide sequence 2 are at least partially reversely complementary to form a double-stranded region; the nucleotide sequence 1 and the nucleotide sequence shown in SEQ ID NO: 1 are equal in length, and no more than 3 nucleotide differences are generated; the nucleotide sequence 2 and the nucleotide sequence shown in SEQ ID NO: 2 are equal in length, and no more than 3 nucleotide differences are generated; nucleotides of the 7th, 8th, and 9th bits of the nucleotide sequence 1 and the 2nd, 6th, 14th, and 16th of the nucleotide sequence 2 are fluoro-modified nucleotides. Also provided are a pharmaceutical composition and a conjugate containing the siRNA.

Abstract: An siRNA conjugate having a structure as represented by formula (1) for inhibiting hepatitis B vims gene expression, comprising siRNA and a conjugated group, wherein the sense strand of the siRNA comprises a nucleotide sequence 1, and the antisense strand comprises a nucleotide sequence 2; the nucleotide sequence 1 and the nucleotide sequence 2 are, at least in part, reversely complementary to form a double-stranded region; the nucleotide sequence 1 and SEQ ID NO: 1 are equal in length and differ by no more than three nucleotides; the nucleotide sequence 2 and SEQ ID NO: 2 are equal in length and differ by no more than three nucleotides. The siRNA conjugate can specifically target liver cells and effectively solve the problem of siRNA delivery in vivo, and shows excellent activity and low toxicity to inhibit HBV gene expression while maintaining high stability of siRNA.