Abstract: The present disclosure provides an siRNA capable of inhibiting expression of a complement protein 5(C5) gene, and a pharmaceutical composition and conjugate containing the siRNA. Each nucleotide in the siRNA is an independent modified or unmodified nucleotide. The siRNA comprises a sense strand and an antisense strand. The sense strand comprises a nucleotide sequence I, and the nucleotide sequence I has the same length and no more than three nucleotide differences from a nucleotide sequence shown in SEQ ID NO: 1. The antisense strand comprises a nucleotide sequence II, and the nucleotide sequence II has the same length and no more than three nucleotide differences from a nucleotide sequence shown in SEQ ID NO: 2. The siRNA, the pharmaceutical composition and the conjugate thereof provided by the present disclosure can effectively treat and/or prevent complement-mediated related diseases, such as myasthenia gravis (MG).

Abstract: A video data inter prediction method is provided, which includes: determining a candidate motion information list of a current picture block, where the candidate motion information list includes at least one first candidate motion information group, at least one second candidate motion information group, the first candidate motion information group is a motion information group determined based on motion information of preset locations on a first neighboring picture block of the current picture block and a motion model of the first neighboring picture block, the second candidate motion information group is a set of motion information of at least two sample locations that are respectively neighboring to at least two preset locations on the current picture block; determining target motion information from the candidate motion information list; and performing inter prediction on the current picture block based on the target motion information.

Abstract: The present invention relates to the field of video image processing, and provides a filtering method and an apparatus, to resolve a problem that subjective quality and objective quality of an image deteriorate because filtering processing cannot be performed on internal blocks of a non-translational motion prediction unit.

Abstract: This application provides a pixel collection circuit comprising an optical-to-electrical converter circuit configured to convert a collected optical signal into an analog signal; an analog-to-digital converter circuit configured to: receive the analog signal from the optical-to- electrical converter circuit; and perform analog-to-digital conversion on the analog signal to obtain a digital signal; a differential circuit configured to: receive the digital signal from the analog-to-digital converter circuit; and obtain a difference signal between a digital signal of a previous triggering moment and the digital signal of a current triggering moment; the previous triggering moment and the current triggering moment are determined by at least a digital clock signal; a comparison circuit configured to receive the difference signal from the differential circuit, and output a pulse signal.

Abstract: The present disclosure relates to systems, non-transitory computer-readable media, and methods for efficiently providing a graphical user interface for visualizing large amounts of data on a single interface. In particular, in one or more embodiments, the disclosed systems utilize topic hierarchies and multidata display elements to intuitively present many types of data for many topics on a single interface. The system also uses an activatable timeline to visualize changes to large amounts of data over time.

Abstract: A method for scheduling EV battery swap based on IoV, in which the roadside units regard battery-swap station clusters with a high degree of potential cooperation as a whole, and gather them into a single battery swap area; taking a service rate of a cluster of swap stations as an assessment target, and mainly examining a service capability, a service quality, and location information of each of swap station nodes themselves, and a current state of those electric vehicles that require to swap battery; providing a solution of the best joint actions for the overall electric vehicles to maintain the overall service balance of every swap station and improve a long-term performance of Internet of Vehicles. According to the invention, a battery of the electric vehicles can be swapped as soon as possible, and every battery swap station can maintain business balance.

Abstract: The present disclosure provides an array substrate, a method of manufacturing the same, and a display panel. The array substrate includes a base substrate, a thin film transistor disposed at a side of the base substrate. The thin film transistor includes a first electrode, a second electrode, and a gate electrode. The array substrate includes a data line disposed at the side of the base substrate The array substrate includes a connection electrode electrically connecting the first electrode of the thin film transistor to the data line. An orthographic projection of an active layer of the thin film transistor on the base substrate is located within an orthographic projection of the gate electrode of the thin film transistor on the base substrate.

Abstract: This application provides a dynamic vision sensor. The sensor converts an optical signal into an electrical signal by using a photoelectric conversion unit, to generate a photovoltage; performs second-order difference on the photovoltage by using a second-order differential circuit; and generates a second-order event signal based on a result of second-order difference. A camera including the sensor can generate an image based on the second-order event signal, where the image represents a change of a light change speed.

Abstract: A method includes obtaining a first motion vector of a motion compensation unit included in an affine code block. The method also includes determining a second motion vector based on the first motion vector, where a precision of the second motion vector matches a motion vector precision of a storage unit corresponding to the motion compensation unit. The method further includes determining a third motion vector based on the second motion vector, where there is a preset correspondence between the third motion vector and the second motion vector, and the third motion vector is used for subsequent encoding/decoding processing.

Abstract: A four-shaft panoramic scanning temperature measuring device with a circulating water-cooling device is provided, which not only improves the working reliability of the probe, but also increases the overall flexibility and scanning measurement efficiency. The circulating water-cooling device is self-cooled. Compared with the conventional single-circulation water-cooling way, the design of five cooling cavities can achieve higher circulating water-cooling efficiency. The four-shaft structure includes a shaft structure for translation, a shaft structure for rotation, a shaft structure for swinging, and a shaft structure with coaxial sight pipe and light pipe. The design of the four-shaft structure is able to panoramically scan the high-temperature components inside the turbine. The temperature measuring device integrates functions of cooling, swinging, translating and rotating together, which solves problems of large size and complex control of the conventional temperature measuring device.

Abstract: An inter prediction method includes parsing, by a processor, a bitstream to obtain a location of a target adjacent image block of a current image block. The method further includes obtaining a preset correspondence between an adjacent image block location and a motion vector precision, wherein in the preset correspondence, locations of at least two adjacent image blocks correspond to different motion vector precisions. The method further includes determining, based on the location of the target adjacent image block and the preset correspondence, a target motion vector precision corresponding to the target adjacent image block. The method further includes determining a motion vector predictor of the current image block based on the location of the target adjacent image block and the target motion vector precision.

Abstract: Provided are an siRNA for inhibiting the expression of the apolipoprotein C3 gene, and a pharmaceutical composition and a conjugate containing the siRNA. Each nucleotide in the siRNA is, respectively and independently, a modified or unmodified nucleotide; the siRNA contains a sense strand and an anti-sense strand; the sense strand includes nucleotide sequence I; nucleotide sequence I has the same length as the nucleotide sequence as shown in SEQ ID NO: 1, and not more than three nucleotides are different; the anti-sense strand contains nucleotide sequence II; and nucleotide sequence II has the same length as the nucleotide sequence as shown in SEQ ID NO: 2, and not more than three nucleotides are different. The siRNA provided by the present disclosure and the pharmaceutical composition and the conjugate thereof can effectively treat and/or prevent dyslipidemia.

Abstract: The present invention relates to the field of video image processing, and provides a filtering method and an apparatus, to resolve a problem that subjective quality and objective quality of an image deteriorate because filtering processing cannot be performed on internal blocks of a non-translational motion prediction unit.

Abstract: The present disclosure relates to the field of display technology, and provides an array substrate, a manufacturing method thereof and a display device. The array substrate includes a display region and a wiring region surrounding thereof. The array substrate further includes a base substrate, a first conductive layer, a first insulating layer, a second conductive layer, a second insulating layer and a patterned shielding layer disposed sequentially thereon. The shielding layer includes a shielding portion in the wiring region. The first and second conductive layers include respectively first and second signal lead wires in the wiring region. There is no overlap between orthographic projections of the first and second signal lead wires on the base substrate. A difference between vertical distances from the first signal lead wire and from the second signal lead wire to the shielding layer is smaller than a thickness of the first insulating layer.

Abstract: Provided is a modified double-stranded oligonucleotide, in which the sense strand comprises a nucleotide sequence 1, the anti-sense strand comprises a nucleotide sequence 2, the nucleotide sequences 1 and 2 are both 19 nucleotides in length, and in the direction from 5? end to 3? end, nucleotides at positions 7, 8 and 9 of the nucleotide sequence 1 and nucleotides at positions 2, 6, 14 and 16 of the nucleotide sequence 2 are all fluoro-modified nucleotides, and each nucleotide at other positions is independently one of non-fluoro-modified nucleotides. Further provided are a pharmaceutical composition and a conjugate comprising the oligonucleotide, and pharmaceutical use thereof.

Abstract: A decoding method includes: parsing a data stream, and if partitioning an image block with a size of 2N×2N using a quadtree partition pattern is allowed, processing a 2N×N first subimage block and a 2N×N second subimage block or an N×2N first subimage block and an N×2N second subimage block in a constraint subimage processing mode, wherein an image block partition pattern obtained for the partitioned second subimage block and the partitioned first subimage block is different from an image block partition pattern obtained after the 2N×2N image block is partitioned using the quadtree partition pattern, where the 2N×N first subimage block and the 2N×N second subimage block or the N×2N first subimage block and the N×2N second subimage block are obtained by partitioning the image block with the size of 2N×2N.

Abstract: The disclosure discloses a channel combining and time-division processing circuit of a dual-plane pulse Doppler radar seeker. The circuit includes a time-division control circuit configured to receive a time-division control signal, control input of an elevation difference channel signal and an azimuth difference channel signal, combine the elevation difference channel signal and the azimuth difference channel signal and output a combined difference channel signal, and a hybrid bridge circuit configured to receive a sum channel signal, combine channels for the sum channel signal and the combined difference channel signal and output signals on a combined channel. With the circuit of the disclosure, signals received from a sum channel, an azimuth difference channel and an elevation difference channel can be combined into received signals from two channels for processing with one received signal processing channel hardware omitted.

Abstract: An siRNA conjugate having a structure as represented by formula (1) for inhibiting hepatitis B vims gene expression, comprising siRNA and a conjugated group, wherein the sense strand of the siRNA comprises a nucleotide sequence 1, and the antisense strand comprises a nucleotide sequence 2; the nucleotide sequence 1 and the nucleotide sequence 2 are, at least in part, reversely complementary to form a double-stranded region; the nucleotide sequence 1 and SEQ ID NO: 1 are equal in length and differ by no more than three nucleotides; the nucleotide sequence 2 and SEQ ID NO: 2 are equal in length and differ by no more than three nucleotides. The siRNA conjugate can specifically target liver cells and effectively solve the problem of siRNA delivery in vivo, and shows excellent activity and low toxicity to inhibit HBV gene expression while maintaining high stability of siRNA.

Abstract: Methods, systems, and computer programs are presented for improving search speed and quality using differential indexing. One method includes an operation for building a first index for a database, the first index being for first tokens resulting from normalizing words in input data. Further, the method includes building a second index for the database, the second index being for second tokens comprising words of the input data eliminated from the first index during the normalizing. The method further includes operations for receiving a raw query for a search of the database, and for generating a search query based on tokens of the raw query. The search query comprises a combined search of the first index and the second index. A search is performed based on the search query, and results of the search are returned for presentation on a display.

Abstract: A method, computer system, and computer program product for file exposure to an intended recipient. A computer system receives a request to view a file is received first, wherein the file is encrypted with a first key generated based on at least one biological feature of an intended recipient. The computer system causes at least one biological feature of a viewer to be captured, wherein the at least one biological feature of the viewer is corresponding to the at least one biological feature of the intended recipient. The computer system generates a second key based on the at least one biological feature of the viewer. The computer decrypts the file with the second key.