Patents by Inventor Shih Chen

Shih Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250250531
    Abstract: The invention primarily relates to a method for isolating and characterizing nucleus pulposus progenitor cells. The method initially involves cutting nucleus pulposus tissue into multiple tissue blocks and then enzymatically digesting these blocks. After digestion, these tissue blocks are cultured in a culture dish. When cells form clusters at the bottom of the dish, specific embryonic stem cell genes (such as Nanog, Oct-4, SOX2) are used to select nucleus pulposus progenitor cells from the clusters. Furthermore, this method employs specific proteins and genetic markers to select nucleus pulposus progenitor cells with mobility and/or mesenchymal stem cell characteristics, as well as to further select cells with anti-inflammatory abilities. Finally, the invention discloses a use of the nucleus pulposus progenitor cells obtained by the method in the manufacture of a pharmaceutical composition for the treatment of lower back pain, offering a new strategy for the treatment of lower back pain.
    Type: Application
    Filed: April 22, 2024
    Publication date: August 7, 2025
    Applicant: ASTEROGENE Biomedical Co., Ltd.
    Inventors: WEI-HUNG CHEN, SHIH-CHEN TSAI
  • Publication number: 20250248144
    Abstract: An infrared sensor includes a substrate, a first electrode, a light-sensing unit, and a second electrode. The substrate is infrared-transmissible. The first electrode is disposed on a surface of the substrate and is infrared-transmissible. The light-sensing unit is disposed on a surface of the first electrode opposite to the substrate, is capable of absorbing and sensing infrared light, and includes a zinc oxide (ZnO)-based layer, a first lead sulfide (PbS)-based modification layer, and a second PbS-based modification layer that are sequentially stacked from the surface of the first electrode. The first PbS-based modification layer includes halide ion-modified PbS, and the second PbS-based modification layer includes thiol-modified PbS. In addition, the second electrode is disposed on a surface of the light-sensing unit opposite to the substrate, and is capable of forming a current flow path by cooperating with the light-sensing unit and the first electrode.
    Type: Application
    Filed: June 4, 2024
    Publication date: July 31, 2025
    Inventors: Hsueh-Shih CHEN, Pei-Cheng HUANG, Chen-Te LIN
  • Publication number: 20250216019
    Abstract: A door lock structure is disclosed. The door lock structure is used to mount a fire door and includes a base, a pressing component, a pressing shell and a locking component. The base is disposed on the fire door and has an accommodation groove, and a groove bottom of the accommodation groove has a first locking hole. The pressing component includes a pressing base, a roller column, a fixing plate, an elastic part and a locking part.
    Type: Application
    Filed: June 6, 2024
    Publication date: July 3, 2025
    Inventors: Shih-Chen CHANG, Chih-Chun KO
  • Publication number: 20250168305
    Abstract: A display system, a display apparatus, and a control method thereof are provided. The display apparatus executes one of a first process and a second process to obtain an input image file. An artificial intelligence model is configured to generate a standard instruction according to the input image file. The display apparatus adjusts an operating setting of the display apparatus according to the standard instruction. The first process includes: obtaining a first original image file related to an environment of the display apparatus by driving an imaging apparatus, and using the first original image file as the input image file. The second process includes: capturing a multimedia content of the display apparatus by driving an image processing module to obtain a second original image file, and using the second original image file as the input image file.
    Type: Application
    Filed: November 20, 2024
    Publication date: May 22, 2025
    Applicant: Coretronic Corporation
    Inventors: Yi-Jun Liao, Kun-Hong Chen, Yu-Hsuan Hsieh, Yun-Shih Chen
  • Publication number: 20250154263
    Abstract: Methods are disclosed for treating chronic lymphocytic leukemia (CLL), and other diseases, comprising administrating to a patient an anti-CLECL1 antibody or antigen-binding fragment thereof, as soluble molecules or as components of CAR-T cells or as bi- or tetra-specific antibodies that co-ligate T cells or NK cells and abnormal cells in CLL or other diseases or as bi- or tetra-specific antibodies that bind only the B cells in CLL or only abnormal cells in other diseases. Methods are disclosed for determining residual disease after therapy or predicting disease relapse in a patient comprising analyzing a blood or bone sample from a patient treated for the disease for the presence of CLECL1+ PF cells using a monoclonal antibody to CLECL1 or antigen-binding fragment thereof, wherein reappearance of CLECL1+ PF cells in the blood of the patient is indicative of development of resistance to therapy. Monoclonal antibodies to CLECL1 are disclosed.
    Type: Application
    Filed: November 14, 2024
    Publication date: May 15, 2025
    Applicant: The Feinstein Institutes for Medical Research
    Inventors: Nicholas Chiorazzi, Shih-Shih Chen, Xiao Jie Yan
  • Publication number: 20250159113
    Abstract: Disclosed are a projection device and a projection method. The projection device includes an optical engine, a distance measuring unit, and a processor. The distance measuring unit is configured to emit testing light to the target area and receive reflected light. The distance measuring unit generates multiple pieces of corresponding distance information according to the reflected lights received and multiple areas of the target area. The processor is configured to: generate area distance information according to the multiple pieces of distance information; select a mode from multiple pieces of sub-area distance information comprised by each piece of area distance information as corrected distance information corresponding to each area; and control the optical engine to project an image beam according to the corrected distance information of each area to form a projected image in the target area.
    Type: Application
    Filed: November 7, 2024
    Publication date: May 15, 2025
    Applicant: Coretronic Corporation
    Inventors: Yi-Jun Liao, Kun-Hong Chen, Yu-Hsuan Hsieh, Yun-Shih Chen
  • Publication number: 20250159120
    Abstract: A projection device and a projection method thereof are provided. The projection device includes an optical engine, a ranging unit, and a processor. The optical engine projects an image beam to a target area to form a first image. The ranging unit emits testing light beams, detects reflected light beams reflected from the testing light beams, and obtains effective sensing information from the reflected light beams. The processor is coupled to the ranging unit and the optical engine, receives the effective sensing information from the ranging unit, and generates first projection distance information according to the effective sensing information. The processor controls the optical engine so that the first image corresponding to the image beam is located within an effective focal length range of the projection device.
    Type: Application
    Filed: November 8, 2024
    Publication date: May 15, 2025
    Applicant: Coretronic Corporation
    Inventors: Kun-Hong Chen, Yi-Jun Liao, Yu-Hsuan Hsieh, Yun-Shih Chen
  • Publication number: 20250106458
    Abstract: An electronic system and a control method thereof are provided. The electronic system includes a projection device and at least one peripheral device. The control method of the electronic system includes: sending an original instruction to a natural language model through the projection device, wherein the projection device has a communication interface and is communicatively connected to the at least one peripheral device through the communication interface; in response to the original instruction corresponding to an operation of the at least one peripheral device, generating at least one standard instruction according to the original instruction through the natural language model; and controlling the at least one peripheral device through the projection device to perform the operation corresponding to the original instruction according to the at least one standard instruction.
    Type: Application
    Filed: September 18, 2024
    Publication date: March 27, 2025
    Applicant: Coretronic Corporation
    Inventors: Kun-Hong Chen, Yi-Jun Liao, Yu-Hsuan Hsieh, Yun-Shih Chen
  • Patent number: 12240559
    Abstract: Various hub motor arrangements, systems, and methods are disclosed. The hub motor arrangement may include a transmission assembly to provide increased torque. The transmission assembly may include a motor gear, a planetary gear, an idler gear, and a ring gear. The idler gear may be positioned farther away from an axis of rotation of the hub motor arrangement compared to the planetary gear. The motor gear may drive the planetary gear, the planetary gear may drive the idler gear, and idler gear may drive the ring gear. The rotation of the ring gear may rotate a housing of the hub motor arrangement to propel a vehicle incorporating the hub motor arrangement.
    Type: Grant
    Filed: June 16, 2022
    Date of Patent: March 4, 2025
    Assignee: Razor USA LLC
    Inventors: Robert Chen, Fu-Yao Wang (Yau Wang), Shih-Chen Lu (Louis Lu), Ian Desberg, Robert Hadley
  • Publication number: 20250044673
    Abstract: A wavelength conversion element is adapted to rotate around a rotation axis. The wavelength conversion element includes a rotating member and a wavelength conversion material. The wavelength conversion material is arranged on the rotating member. The wavelength conversion material is configured to convert a laser beam into a conversion beam. The rotating member is configured to drive the wavelength conversion material to rotate around the rotation axis. The wavelength conversion element has a light-transmitting area. The light-transmitting area is surrounded by the rotating member. The light-transmitting area is configured to allow at least one of the laser beam and the conversion beam to pass through.
    Type: Application
    Filed: July 16, 2024
    Publication date: February 6, 2025
    Applicant: Coretronic Corporation
    Inventor: Shih-Chen Chiou
  • Publication number: 20250020408
    Abstract: A crucible lifting device includes a vacuum chamber, a vacuum chamber lower seat and a crucible lifting assembly. The vacuum chamber lower seat is arranged orthogonally at the bottom of the vacuum chamber, the vacuum chamber lower seat including a plurality of coupling parts arranged orthogonally at the vacuum chamber lower seat and on a side away from the vacuum chamber. The crucible lifting assembly is arranged on the vacuum chamber lower seat and on the side away from the vacuum chamber. The crucible lifting assembly includes a plurality of multi-rotation angle guides, one end of each multi-rotation angle guide connected to each coupling part; a plurality of guide rods, one end of each guide rod connected to the other end of each multi-rotation angle guide; and a plurality of guide rod accommodating parts, each guide rod accommodating part configured to correspond to each guide rod.
    Type: Application
    Filed: October 6, 2023
    Publication date: January 16, 2025
    Applicant: KENMEC MECHANICAL ENGINEERING CO., LTD.
    Inventors: Shih-Chen CHANG, Chih-Chun KO
  • Publication number: 20240422969
    Abstract: A layout structure of a memory cell array for a non-volatile memory is provided. The memory cell array includes plural memory cells. Each memory cell includes a capacitor, an erase gate element, a select transistor, a floating gate transistor and a switch transistor. Moreover, plural wells are formed in a semiconductor substrate, and a floating gate is formed over the semiconductor substrate. The locations of the well regions and the shape of the floating gate are specially designed. Moreover, the plural memory cells with at least two shapes are constructed on the semiconductor substrate. Consequently, the layout area of the layout structure of the memory cell array can be effectively reduced.
    Type: Application
    Filed: May 20, 2024
    Publication date: December 19, 2024
    Inventors: Chih-Hsin CHEN, Shih-Chen WANG, Bo-Chang LI
  • Publication number: 20240407375
    Abstract: Provided is a stuffing food forming apparatus, the flipping units are utilized to replace the wrapping operation of the wrapper used in the rolling method in the prior art. The shape of non-strip stuffing can be maintained to a large extent, and the technical problems encountered in the automation of plate-shaped stuffing foods are solved.
    Type: Application
    Filed: July 19, 2023
    Publication date: December 12, 2024
    Inventors: JYUN-SHIH CHEN, JUI-FENG CHU
  • Publication number: 20240409888
    Abstract: The present invention primarily relates to a method for in vitro culturing and expanding nucleus pulposus cells derived from an intervertebral disc. A secondary objective of the present invention is to provide a method for improving lower back pain by administering an effective amount of a pharmaceutical composition containing said nucleus pulposus cells obtained through the aforementioned method to subjects experiencing lower back pain.
    Type: Application
    Filed: October 26, 2023
    Publication date: December 12, 2024
    Applicant: RegenCELLS Biomedical Co. Ltd.
    Inventors: Shih-Chen TSAI, Wei-Hung CHEN
  • Publication number: 20240401383
    Abstract: A gate assembly includes a base member, a door cover member, and an operating member. The door cover member is arranged on the base member, and includes a body, a movable portion, and two gate portions. The body is provided with a through slot and two protruding posts. The movable portion is arranged on the body and is movable relative to the body along a first axis. The movable portion is provided with two limiting posts and an accommodating portion. Two gate portions are movably arranged on the body and the movable portion. Each of the gate portions is provided with a limiting hole formed in an inclined direction and a positioning hole formed along a second axis orthogonal to the first axis. Each of the limiting posts extends through the limiting hole, and each of the protruding posts extends through the positioning hole.
    Type: Application
    Filed: March 22, 2024
    Publication date: December 5, 2024
    Inventor: Shih-Chen CHENG
  • Patent number: 12160692
    Abstract: A projection apparatus, an illumination apparatus thereof, and a light source driving method thereof are provided. A control module converts a bit control signal into first light source timing signals, converts the first light source timing signals into second light source timing signals according to a lookup table, generates a driving current corresponding to each light source according to the lookup table, outputs second light source driving signals corresponding to the light sources according to the second light source timing signals. The lookup table includes a driving current ratio corresponding to the light sources. A driving module drives the light sources according to the second light source driving signals and the driving current for the light sources to have overlapping light-emitting timings.
    Type: Grant
    Filed: March 15, 2023
    Date of Patent: December 3, 2024
    Assignee: Coretronic Corporation
    Inventors: Hsin-Chang Huang, Chien-Yi Yang, Pei-Jen Liao, Yun-Shih Chen, Wei-Chih Su
  • Publication number: 20240285556
    Abstract: In one aspect, the disclosure relates to methods and compositions for treatment of cancer cachexia. In a further aspect, the composition is a pharmaceutical composition comprising a class I/IIB HDAC inhibitor and an androgen. In a still further aspect, the method of treatment comprises administering a class I/IIB HDAC inhibitor and an androgen to a subject or patient who has been diagnosed as having cancer cachexia. In some aspects, the class I/IIB HDAC inhibitor is a compound known as AR-42.
    Type: Application
    Filed: March 25, 2024
    Publication date: August 29, 2024
    Inventors: Ching-Shih Chen, Christopher C. Coss, Samuel Kulp, Yu-Chou Tseng, Tanios Bekaii-Saab
  • Publication number: 20240267498
    Abstract: A projection device, including a projection module, a projection lens, a distance sensor, a focus adjustment module, and a control unit, is provided. The projection module is configured to generate an image beam. The projection lens is disposed on a transmission path of the image beam. The focus adjustment module is connected to the projection lens. The control unit is configured to enable the projection device to enter a focus mode; enable the projection module to project the image beam to a projection surface; enable the distance sensor to sense a projection distance; calculate a focus adjustment parameter by using an auto focus transfer function according to the projection distance; and control the focus adjustment module to adjust a focal length of the projection lens according to the focus adjustment parameter. An auto focus method is also provided.
    Type: Application
    Filed: January 12, 2024
    Publication date: August 8, 2024
    Applicant: Coretronic Corporation
    Inventors: Yi-Jun Liao, Kun-Hong Chen, Yu-Hsuan Hsieh, Yun-Shih Chen
  • Publication number: 20240248993
    Abstract: A data protection method is provided. The method includes resetting a system, performing a security boot operation to check whether a malware is installed in the system, inputting a first key to access initial data, storing the initial data to a volatile memory of the system, and running a predetermined program in the system with the initial data.
    Type: Application
    Filed: January 19, 2023
    Publication date: July 25, 2024
    Applicant: iMQ Technology Inc.
    Inventor: Shih-Chen Peng
  • Publication number: 20240228871
    Abstract: A composite quantum dot includes a quantum dot and a protecting unit. The quantum dot includes a dot body containing a first layer having a composition of M1A1, and a passivating unit containing a passivating metal ion and bound to the dot body. M1 is one of Zn, Sn, Pb, Cd, In, Ga, Ge, Mn, Co, Fe, Al, Mg, Ca, Sr, Ba, Ni, Ag, Ti and Cu, and A1 is one of Se, S, Te, P, As, N, I and O. The protecting unit adsorbs on the quantum dot and includes an amine compound and/or a primary ammonium salt thereof. A method for preparing the composite quantum dot and a method for detecting metal ions in an analyte aqueous solution using the composite quantum dot, as well as a passivated quantum dot and a preparation thereof, are also disclosed.
    Type: Application
    Filed: December 21, 2023
    Publication date: July 11, 2024
    Inventors: Hsueh-Shih CHEN, Pin-Ju CHEN