Abstract: A slider for a slide fastener includes a slider body (11) and two pullers (20, 21) pivotally attached to the slider body (11). The slider body (11) forms an upper wing (12), a lower wing (13), a connecting post (14) connecting the upper and lower wings, and side flanges (15). The side flanges protrude from side edges of the upper and lower wings towards a geometrical mid-plane (P) that lies between the wings (12, 13), so as to form a Y-shaped channel (19) between the upper and lower wings. The upper wing (12) and the lower wing (13) have respective opposite outer surfaces (23, 24) which are substantially flat, and are symmetrical with respect to the geometrical mid-plane (P). At least one locking protrusion (30) protrudes inwardly into the Y-shaped channel (19) from at least one of the side flanges (15) of the slider body (11).

Abstract: The purpose of the present invention is to provide a method for producing a very stable, cyclized mutant protein such that high cyclization efficiency is achieved while the number of amino acids added is minimal and the biological properties of an original protein are maintained. In view of conformational information about the original protein, secondary structure-free regions at N/C terminal portions are deleted. Then, a protein database is screened for proteins with secondary structures similar to those of N/C terminal residues of a secondary structure-forming portion after the deletion. The screening results are used to determine the amino acid length of a loop structure through which the N-terminus and the C-terminus of the secondary structure-forming portion of the original protein are to be connected. A cyclized mutant protein is finally produced having a loop structure with the determined amino acid length.

Abstract: A slider for a slide fastener in which the slider is attached to fastener chains is provided. The slider includes a first member and a second member. The first member includes an upper blade, a lower blade, a guide post connected between the upper blade and the lower blade, and a connecting post protruding from the upper blade. The second member includes a first arm and a second arm separated from each other, is attached to the first member by the first arm and the second arm, and is configured to rotate along an upper-lower direction relative to the first member and around a fulcrum provided on the upper blade or the lower blade. The first member or the second member is provided with a flange. Three or more fit sections are formed between the first member and the second member.

Abstract: An information processing device used for a convolutional neural network includes a processor configured to acquire input data and process the input data by using a convolution layer that executes convolution processing and a pooling layer that executes pooling processing, in which the processor is configured to divide the acquired input data into processing areas having an overlapping area in which processing areas overlap and a non-overlapping area in which processing areas do not overlap, and the processor is configured to, when the processor executes processing of the input data in the processing area, execute the convolution processing or the pooling processing in the non-overlapping area, and execute the processing by reusing a processing result of the convolution processing or a processing result of the pooling processing in the overlapping area.

Abstract: A wafer processing method includes a pattern region detecting step, an evaluation region setting step, and an evaluation region deploying step. The pattern region detecting step is a step of detecting a period and positional information in which a substantially identical image appears in an imaged image and detecting a pattern region corresponding to one period. The evaluation region setting step is a step of detecting a position in which no metallic pattern is formed on planned dividing lines and setting the position as an evaluation region for evaluating quality of a processed groove. The evaluation region deploying step is a step of recording the position of the evaluation region in the pattern region and deploying the evaluation region at similar positions in different pattern regions.

Abstract: A slider for slide fastener includes: a body including a pull tab attachment post; and a pull tab. The pull tab includes: a coupling member including an exposed portion and an embedded portion; and a pinching member including a first pinching portion including an annular end portion having an opening through which the embedded portion is to be inserted, and a second pinching portion provided to the first pinching portion with the embedded portion interposed therebetween. At least one of a front end surface and a rear end surface of the pull tab attachment post has a protrusion. And when the pull tab is tilted toward at least one of a front side and a rear side of the body, the protrusion locks the pull tab to restrict rotation of the pull tab.

Abstract: A laser processing apparatus includes a laser beam applying unit for applying a laser beam to a workpiece, an image capturing unit for producing a captured image of the workpiece that includes a captured image of light emitted from the workpiece when the laser beam is applied to the workpiece by the laser beam applying unit, and a control unit. The laser beam applying unit includes a laser oscillator for emitting a laser beam and a condensing lens for converging the laser beam onto the workpiece. The control unit includes a determining section for determining a state of the laser beam applied to the workpiece, on the basis of the shape of the captured image of the light that is included in the captured image of the workpiece.

Abstract: A slider for a slide fastener useable with a slider with an automatic stop function to secure a tab to enable automatic engagement and prevent swinging of the tab, regardless of the type of tab, when the tab is tilted to an engaged portion side. An engaging portion is formed in an attachment hole of the tab. An engaged portion is formed in the slider body or the tab attachment part. When the tab is tilted to be almost parallel to an upper blade on the engaged portion side of the tab attachment part, due to a biasing force of the spring member, the lock pin moves the shaft portion of the tab downward and to an opposite side of a tilted direction, and a tip portion of the engaging portion of the tab is pulled into to be engaged with the engaged portion side of the tab attachment part.

Abstract: The present invention addresses the problem of providing an ultraviolet light-induced inflammation suppressing agent. The present invention is based on the finding that an alternative autophagy (Atg5/Atg7-independent autophagy) participates in the suppression of ultraviolet light-induced inflammation. Thus, the above problem is solved by providing an alternative autophagy inducing agent.

Abstract: A slider for a slide fastener useable with a slider with an automatic stop function to secure a tab to enable automatic engagement and prevent swinging of the tab, regardless of the type of tab, when the tab is tilted to an engaged portion side. An engaging portion is formed in an attachment hole of the tab. An engaged portion is formed in the slider body or the tab attachment part. When the tab is tilted to be almost parallel to an upper blade on the engaged portion side of the tab attachment part, due to a biasing force of the spring member, the lock pin moves the shaft portion of the tab downward and to an opposite side of a tilted direction, and a tip portion of the engaging portion of the tab is pulled into to be engaged with the engaged portion side of the tab attachment part.

Abstract: A slider for a slide fastener in which the slider is attached to fastener chains is provided. The slider includes a first member and a second member. The first member includes an upper blade, a lower blade, a guide post connected between the upper blade and the lower blade, and a connecting post protruding from the upper blade. The second member includes a first arm and a second arm separated from each other, is attached to the first member by the first arm and the second arm, and is configured to rotate along an upper-lower direction relative to the first member and around a fulcrum provided on the upper blade or the lower blade. The first member or the second member is provided with a flange. Three or more fit sections are formed between the first member and the second member.

Abstract: A computer-implemented method is for designing a composite material in which reinforcement fiber base materials are laminated. The composite material includes a hole extending in a lamination direction of the reinforcement fiber base materials and a reinforcement part provided around the hole. The method includes calculating a strain value generated in the composite material based on design factors and a predetermined load condition, the design factors including a shape of the hole, a shape of the reinforcement part, and an orientation angle of each of the reinforcement fiber base materials in respective layers of the reinforcement part; and optimizing the design factors based on a genetic algorithm such that the calculated strain value tends to decrease.

Abstract: The present invention relates to a novel polypeptide having affinity for proteins partially including a CH1-CL domain forming a non-native three-dimensional structure and capable of being suitably used for detecting, immobilizing, or removing these proteins and relates to use of the polypeptide. Specifically, disclosed are a polypeptide consisting of an amino acid sequence represented by any one of the following formulas 1 to 3: (1) P-Q-x-I-x-L-x-[IL]-[NT]-[YW] (SEQ ID NO: 1), (2) Y-D-P-E-T-G-T-W-P-Q-x-I-x-L-x-[IL]-[NT]-[YW] (SEQ ID NO: 4), and (3) P-N-S-G-G-G-G-S-Y-D-P-E-T-G-T-W-P-Q-x-I-x-L-x-[IL]-[NT]-[YW] (SEQ ID NO: 7) (wherein x represents an amino acid residue; and brackets represent any one of the amino acid residues within the brackets), and a method of using the polypeptide to detect, purify, or remove a protein partially including a CH1-CL domain forming a non-native three-dimensional structure.

Abstract: A wafer processing method includes a pattern region detecting step, an evaluation region setting step, and an evaluation region deploying step. The pattern region detecting step is a step of detecting a period and positional information in which a substantially identical image appears in an imaged image and detecting a pattern region corresponding to one period. The evaluation region setting step is a step of detecting a position in which no metallic pattern is formed on planned dividing lines and setting the position as an evaluation region for evaluating quality of a processed groove. The evaluation region deploying step is a step of recording the position of the evaluation region in the pattern region and deploying the evaluation region at similar positions in different pattern regions.

Abstract: The present invention relates to a method for suppressing aggregation of polypeptide. Specifically, the present invention relates to a method for suppressing, in a solution comprising an antibody or an Fc region-containing protein, formation of an aggregate derived from an antibody or an Fc region-containing protein having a non-native conformation, the method comprising: the steps of (i) binding an AF.2A1 polypeptide or an analog thereof with an aggregate derived from the antibody or Fc region-containing protein having a non-native conformation in the solution; and (ii) collecting the aggregate bound to the polypeptide or analog thereof from the solution.

Abstract: A slider for slide fastener includes: a body including a pull tab attachment post; and a pull tab. The pull tab includes: a coupling member including an exposed portion and an embedded portion; and a pinching member including a first pinching portion including an annular end portion having an opening through which the embedded portion is to be inserted, and a second pinching portion provided to the first pinching portion with the embedded portion interposed therebetween. At least one of a front end surface and a rear end surface of the pull tab attachment post has a protrusion. And when the pull tab is tilted toward at least one of a front side and a rear side of the body, the protrusion locks the pull tab to restrict rotation of the pull tab.

Abstract: A pin insertion hole is formed in an outer member, and a pin groove is formed in an inner member. A positioning device includes a pin entering the pin insertion hole and the pin groove, and a groove contact member coming in contact with a groove side surface of the pin groove. In one member of the pin and the groove contact member, a position restriction concave portion recessed in a direction away from the other member is formed in a portion facing the other member. In the other member, a claw portion entering the position restriction concave portion and coming into contact with the position restriction concave portion is formed as a portion of the other member is plastically deformed.

Abstract: In an on-vehicle system, on-vehicle device and gateway are connected via a first network, and the gateway and relay are connected via a second network. The relay performs open-close control of a gate, using a TAS standard of Ethernet TSN. The gateway receives first and second packets including given data, generates a third packet including the first and second packets, and sends the third packets at the transmission timing that is a timing the gate is placed in from closed state to open state to the relay. The relay receives the third packet from the gateway. The relay switches timing to transfer data, for each type of data, and transfer the third packet to the other relay, during a period in which the gate for the type of data is in an open state.

Abstract: There is provided a slider for a slide fastener. A pull-tab attachment portion is provided on a slider body portion. A pull-tab is attached on the pull-tab attachment portion. The pull-tab has a handle portion and a connection portion connected to the pull-tab attachment portion. The connection portion includes a shaft portion and a pair of rod portions made of metal and extending from both ends of the shaft portion toward the handle portion. The shaft portion has a core portion made of metal and a resin portion made of resin and covering at least a part of a circumference of the core portion. At least a part of an outer circumferential surface of the resin portion is in contact with an inner circumferential surface of the pull-tab attachment portion.