Abstract: In an on-vehicle system, on-vehicle device and gateway are connected via a first network, and the gateway and relay are connected via a second network. The relay performs open-close control of a gate, using a TAS standard of Ethernet TSN. The gateway receives first and second packets including given data, generates a third packet including the first and second packets, and sends the third packets at the transmission timing that is a timing the gate is placed in from closed state to open state to the relay. The relay receives the third packet from the gateway. The relay switches timing to transfer data, for each type of data, and transfer the third packet to the other relay, during a period in which the gate for the type of data is in an open state.

Abstract: There is provided a slider for a slide fastener. A pull-tab attachment portion is provided on a slider body portion. A pull-tab is attached on the pull-tab attachment portion. The pull-tab has a handle portion and a connection portion connected to the pull-tab attachment portion. The connection portion includes a shaft portion and a pair of rod portions made of metal and extending from both ends of the shaft portion toward the handle portion. The shaft portion has a core portion made of metal and a resin portion made of resin and covering at least a part of a circumference of the core portion. At least a part of an outer circumferential surface of the resin portion is in contact with an inner circumferential surface of the pull-tab attachment portion.

Abstract: A support device supports an inner member of a fixed body including the inner member and an outer member, the inner member being arranged around a rotating body and divided into upper and lower sections and the outer member being arranged in at least a part around the inner member and divided into upper and lower sections.

Abstract: A pin insertion hole penetrating an outer member from an outer circumferential side to an inner circumferential side is formed in the outer member. A pin groove that is concave from an outer circumferential side to an inner circumferential side is formed in an inner member. A positioning device includes a pin that is inserted into the pin insertion hole of the outer member and the pin groove of the inner member, a liner holder that comes in contact with a groove side surface of the pin groove, and a liner that is disposed between the liner holder and the pin in the pin groove.

Abstract: Provided are a communication device and a communication restriction program capable of suppressing invalid message transmission to a network by injecting an invalid program. The ECU includes a CAN controller having a register group storing a value concerning communication with a different ECU and a processing unit processing a value for the register group. The ECU switches the mode between the full control mode in which writing and reading are allowed for the register group in the CAN controller and the restriction mode wherein writing and reading are restricted for a part of the registers in the register group. The ECU sets a predetermined period from activation corresponding to the full control mode, and switches the full control mode to the restriction mode after the predetermined period elapses. After switching to the restriction mode, the ECU will not switch the mode to the full control mode.

Abstract: In an on-vehicle system, on-vehicle device and gateway are connected via a first network, and the gateway and relay are connected via a second network. The relay performs open-close control of a gate, using a TAS standard of Ethernet TSN. The gateway receives first and second packets including given data, generates a third packet including the first and second packets, and sends the third packets at the transmission timing that is a timing the gate is placed in from closed state to open state to the relay. The relay receives the third packet from the gateway. The relay switches timing to transfer data, for each type of data, and transfer the third packet to the other relay, during a period in which the gate for the type of data is in an open state.

Abstract: The present invention relates to a novel polypeptide having affinity for proteins partially including a CH1-CL domain forming a non-native three-dimensional structure and capable of being suitably used for detecting, immobilizing, or removing these proteins and relates to use of the polypeptide. Specifically, disclosed are a polypeptide consisting of an amino acid sequence represented by any one of the following formulas 1 to 3: (1) P-Q-x-I-x-L-x-[IL]-[NT]-[YW] (SEQ ID NO: 1), (2) Y-D-P-E-T-G-T-W-P-Q-x-I-x-L-x-[IL]-[NT]-[YW] (SEQ ID NO: 4), and (3) P—N-S-G-G-G-G-S-Y-D-P-E-T-G-T-W-P-Q-x-I-x-L-x-[IL]-[NT]-[YW] (SEQ ID NO: 7) (wherein x represents an amino acid residue; and brackets represent any one of the amino acid residues within the brackets), and a method of using the polypeptide to detect, purify, or remove a protein partially including a CH1-CL domain forming a non-native three-dimensional structure.

Abstract: The present invention relates to a method for suppressing aggregation of polypeptide. Specifically, the present invention relates to a method for suppressing, in a solution comprising an antibody or an Fc region-containing protein, formation of an aggregate derived from an antibody or an Fc region-containing protein having a non-native conformation, the method comprising: the steps of (i) binding an AF.2A1 polypeptide or an analog thereof with an aggregate derived from the antibody or Fc region-containing protein having a non-native conformation in the solution; and (ii) collecting the aggregate bound to the polypeptide or analog thereof from the solution.

Abstract: A slider for slide fasteners may include a slider body and a closure part. The closure part may include a closure portion for closing the gap between a free end portion of a pull tab attachment post and an upper blade; an upper engaging portion provided above the closure portion and engageable with the free end portion of the pull tab attachment post and a leg portion provided below the closure portion. The leg portion may include a rod portion extending from the closure portion along the coupling post and a lower engaging portion coupled to the rod portion and engageable with a lower blade.

Abstract: A computer-implemented method is for designing a composite material in which reinforcement fiber base materials are laminated. The composite material includes a hole extending in a lamination direction of the reinforcement fiber base materials and a reinforcement part provided around the hole. The method includes calculating a strain value generated in the composite material based on design factors and a predetermined load condition, the design factors including a shape of the hole, a shape of the reinforcement part, and an orientation angle of each of the reinforcement fiber base materials in respective layers of the reinforcement part; and optimizing the design factors based on a genetic algorithm such that the calculated strain value tends to decrease.

Abstract: There is provided a slider for a slide fastener. A pull-tab attachment portion is provided on a slider body portion. A pull-tab is attached on the pull-tab attachment portion. The pull-tab has a handle portion and a connection portion connected to the pull-tab attachment portion. The connection portion includes a shaft portion and a pair of rod portions made of metal and extending from both ends of the shaft portion toward the handle portion. The shaft portion has a core portion made of metal and a resin portion made of resin and covering at least a part of a circumference of the core portion. At least a part of an outer circumferential surface of the resin portion is in contact with an inner circumferential surface of the pull-tab attachment portion.

Abstract: The purpose of the present invention is to provide a method for producing a very stable, cyclized mutant protein such that high cyclization efficiency is achieved while the number of amino acids added is minimal and the biological properties of an original protein are maintained. In view of conformational information about the original protein, secondary structure-free regions at N/C terminal portions are deleted. Then, a protein database is screened for proteins with secondary structures similar to those of N/C terminal residues of a secondary structure-forming portion after the deletion. The screening results are used to determine the amino acid length of a loop structure through which the N-terminus and the C-terminus of the secondary structure-forming portion of the original protein are to be connected. A cyclized mutant protein is finally produced having a loop structure with the determined amino acid length.

Abstract: A pin insertion hole is formed in an outer member, and a pin groove is formed in an inner member. A positioning device includes a pin entering the pin insertion hole and the pin groove, and a groove contact member coming in contact with a groove side surface of the pin groove. In one member of the pin and the groove contact member, a position restriction concave portion recessed in a direction away from the other member is formed in a portion facing the other member. In the other member, a claw portion entering the position restriction concave portion and coming into contact with the position restriction concave portion is formed as a portion of the other member is plastically deformed.

Abstract: Provided are a communication device and a communication restriction program capable of suppressing invalid message transmission to a network by injecting an invalid program. The ECU includes a CAN controller having a register group storing a value concerning communication with a different ECU and a processing unit processing a value for the register group. The ECU switches the mode between the full control mode in which writing and reading are allowed for the register group in the CAN controller and the restriction mode wherein writing and reading are restricted for a part of the registers in the register group. The ECU sets a predetermined period from activation corresponding to the full control mode, and switches the full control mode to the restriction mode after the predetermined period elapses. After switching to the restriction mode, the ECU will not switch the mode to the full control mode.

Abstract: The purpose of the present invention is to provide a method for producing a very stable, cyclized mutant protein such that high cyclization efficiency is achieved while the number of amino acids added is minimal and the biological properties of an original protein are maintained. In view of conformational information about the original protein, secondary structure-free regions at N/C terminal portions are deleted. Then, a protein database is screened for proteins with secondary structures similar to those of N/C terminal residues of a secondary structure-forming portion after the deletion. The screening results are used to determine the amino acid length of a loop structure through which the N-terminus and the C-terminus of the secondary structure-forming portion of the original protein are to be connected. A cyclized mutant protein is finally produced having a loop structure with the determined amino acid length.

Abstract: A slider includes lower flanges placed on left and right side edges of a lower wing plate. Each of the lower flanges includes a downwardly inclined surface portion which is placed on the shoulder-opening-side tip portion on a side of its upper surface and on an outer side in a width direction of the slider, and which downwardly inclines toward a shoulder and downwardly inclines toward the outer side in the width direction of the slider. According to this, in a slide fastener having the slider, even if a sliding operation of the slider is repeated in the slide fastener, it is possible to avoid defects that the lower flange of the slider comes into sliding contact with the fastener tape and the fastener tape is broken, and it is possible to extend the life of the fastener tape.

Abstract: Disclosed is a molecular library comprising a group of a plurality of molecules, wherein each member of the library is a polypeptide having a randomized sequence moiety and a microprotein moiety. The microprotein is a protein comprising an amino acid sequence of 30 or less amino acid residues having the ability to form a particular conformation by spontaneous folding in a solution and is, for example, chignolin comprising the amino acid sequence represented by SEQ ID NO: 1. Also, disclosed is a method for identifying a novel functional molecule using the library of the present invention.

Abstract: A slider for slide fasteners may include a slider body and a closure part. The closure part may include a closure portion for closing the gap between a free end portion of a pull tab attachment post and an upper blade; an upper engaging portion provided above the closure portion and engageable with the free end portion of the pull tab attachment post and a leg portion provided below the closure portion. The leg portion may include a rod portion extending from the closure portion along the coupling post and a lower engaging portion coupled to the rod portion and engageable with a lower blade.