Abstract: Methods, devices and computer program products for storing and accessing data are provided, and can effectively improve the performance and scalability of a storage system. For example, a method comprises sending, at a client device and to a seed server of a plurality of servers communicatively coupled to the client device, a request for storing data; receiving a response to the request from the seed server, the response comprising an indication on at least one server of the plurality of servers for storing the data into a target storage device; and sending, to the at least one server, at least one request for storing the data into the target storage device, such that the at least one server stores the data into the target storage device.

Abstract: The present disclosure relates to a method, device and computer program product for managing data placement. In the method for managing data placement, in response to receiving a backup request for backing up raw data, the raw data is stored in a first storage system so as to form a raw copy. Metadata corresponding to the raw data is obtained, the metadata comprising abstract information of the raw data. The metadata is stored in a blockchain system in a second storage system so as to form a metadata copy, the first storage system and the second storage system being independent storage systems provided by a first vendor and a second vendor respectively. The raw data is managed by using the raw copy and the metadata copy. In the present disclosure, the raw copy and the metadata copy are stored to different storage systems, so that it may be judged whether a copy has been tampered with, and further higher security may be provided.

Abstract: A linker peptide for constructing a fusion protein. The linker peptide comprises a flexible peptide and a rigid peptide. The flexible peptide consists of one or more flexible units. The rigid peptide consists of one or more rigid units. The flexible unit comprises two or more amino acid residues selected from Gly, Ser, Ala, and Thr. The rigid unit comprises a human chorionic gonadotropin ?-subunit carboxy-terminal peptide (CTP) bearing a plurality of glycosylation sites. The linker peptide can more effectively eliminate mutual steric hindrance of two fusion molecules, decreasing a reduction/loss of polymerization or activity resulting from improper folding of an active protein or a conformational change. On the other hand, the negatively charged, highly sialylated CTP can resist renal clearance, further prolonging a half-life of a fused molecule and enhancing bioavailability of a fused protein.

Abstract: Embodiments of the present disclosure relate to a method, an electronic device, and a computer program product for storing and accessing data. A method for storing data includes: dividing, in response to receiving a request for storing data from a client, the data into a plurality of data blocks; storing the plurality of data blocks in a plurality of servers respectively; generating metadata of the data to record corresponding addresses for storing the plurality of data blocks in the plurality of servers; and storing the generated metadata in a metadata repository. The embodiments of the present disclosure can effectively improve data transmission efficiency, data availability, and data security in a cloud storage system.

Abstract: The invention relates to an antenna and an electronic device. The antenna has a radiation part, a grounding sheet arranged separated from the radiation part and a number of ground connection parts. The radiation part has four radiators forming a first gap and a second gap. Each radiator is electrically connected to the grounding sheet through a ground connection part. The ground connection part includes at least an attaching sheet and a number of metal through holes. Each side of opposite two sides of each attaching sheet is electrically connected to at least one of the metal through holes. The electronic device includes the antenna. According to the technical scheme, the antenna has the advantage of low profile.

Abstract: A TBM-mounted virtual reconstruction system and method for a tunnel surrounding rock structure, the method including: obtaining image information of surrounding rock; receiving the image information of the surrounding rock; transforming and splicing pictures taken at different angles, to form a complete image reflecting the surrounding rock; recognizing and describing a surrounding rock feature of the complete image, and transmitting the annotated image to a virtual reconstruction module; displaying the complete image with a description of the surrounding rock feature by using a virtual reality device, to reflect surrounding rock situations at different angles/different positions. This has the advantages of high equipment automation, not prolonging the construction time, not requiring the sketcher to enter the tunnel, precise surrounding rock feature parameters, and supporting remote control.

Abstract: Techniques for thermal based wireless configuration are described and may be implemented via a wireless device to adapt antennas and/or wireless beams of the wireless device based on a thermal condition. Generally, the described techniques enable the wireless device to compensate for thermal conditions that occur at different antennas, such as high temperatures that may degrade antenna and device performance.

Abstract: Techniques for process based antenna configuration are described, and may be implemented via a wireless device to identify different usage scenarios and to adapt antenna configurations to optimize wireless performance based on the scenarios. For instance, the described techniques enable a wireless device to be calibrated for wireless communication by identifying different obstruction states of a wireless device that correspond to ways that the wireless device is held (e.g., grasped) by a user in different scenarios. The obstruction states are then correlated to antenna positions in the wireless device to prioritize (e.g., activate) antennas that are relatively unobstructed, such as by activating unobstructed antennas and/or deactivating obstructed antennas. Further, calibration can take into specific processes (e.g., applications) and specific users to calibrate an optimize wireless performance based on ways in which a user typically interacts with a process.

Abstract: Disclosed is a fusion protein of a mutated recombinant single-chain human coagulation factor VIII (FVIII), a preparation method therefor, and a use thereof. The fusion protein sequentially comprises, from an N-terminus to a C-terminus, a mutated single-chain human FVIII having a partially deleted B-domain, a flexible peptide linker, at least one rigid unit of a carboxyl-terminal peptide of a human chorionic gonadotropin beta subunit, and a half-life prolonging moiety (preferably an IgG Fc variant). The fusion protein has a similar biological activity to a recombinant FVIII, a prolonged active half life in vivo, and better stability in vitro and in vivo, and thus improves the pharmacokinetics and efficacy of the fusion protein.

Abstract: Provided is a bone conduction earphone that includes a main body, and a bone conduction speaker and a passive radiator that are mounted on the main body. The passive radiator is connected to the bone conduction speaker through a connecting rod. When vibrating by being excited by an audio signal, the bone conduction speaker drives the passive radiator to vibrate synchronously through the connecting rod. The passive radiator and the bone conduction speaker cooperate with each other to form a multi-vibration system, thereby effectively enhancing the quality of vibration, improving the effect of sound field radiation, and improving the frequency response, especially remedying the deficiencies in low-frequency response.

Abstract: Disclosed is a bispecific antibody that specifically binds to surface antigens CD3 of immune cells and CD20 antigens on the surfaces of tumor cells, and that can bind to human CD3 with high affinity, inducing T cell proliferation, and mediating tumor cell killing. The bispecific antibody in an in vitro test was able to mediate the specific killing of target cells by T cells. The construction method thereof is simple, avoiding the possibility of mismatch between two sets of light chains and heavy chains of heterobispecific antibodies, thereby reducing the difficulty of antibody purification. The affinity of the obtained antibody is high, the side effects caused by cytokines are small, and safety is high.

Abstract: The present invention provides a video sticker processing method and device. The method comprises: performing face recognition and speech recognition on video to be processed separately to obtain face position data when face recognition is successful, and speech recognition text when speech recognition is successful; matching speech recognition text with description text of each sticker in sticker library to obtain a target sticker, and obtaining a target video frame according to speech recognition text; adding target sticker to default position or target position of target video frame; wherein, target position is calculated according to the face position data. The present invention can automatically determine the target sticker and its added position according to the face recognition result and the speech recognition result of the video to be processed, realize the intelligent selection and placement of the target sticker, and improve the processing efficiency of the video sticker.

Abstract: Illustrative embodiments include a method, a device, and a computer program product for managing an image of a container. In a method for managing an image of a container in a host device, a first image of a first container is received, wherein the first image includes a first set of image layers for implementing a first set of services of the first container respectively. The first image is loaded to deploy the first container at the host device. Based on an attribute of an image layer in the first set of image layers, an expiration time is set for the image layer. In response to determining that the expiration time is reached, the image layer is deleted from the host device. Stored image layers can be reused to reduce the transmission bandwidth for remotely downloading the image layers. A corresponding device and a corresponding computer program product are provided.

Abstract: A method of fabricating a semiconductor device having two dimensional (2D) lateral hetero-structures includes forming alternating regions of a first metal dichalcogenide film and a second metal dichalcogenide film extending along a surface of a first substrate. The first metal dichalcogenide and the second metal dichalcogenide films are different metal dichalcogenides. Each second metal dichalcogenide film region is bordered on opposing lateral sides by a region of the first metal dichalcogenide film, as seen in cross-sectional view.

Abstract: The invention provides an antibody and/or an antigen binding fragment that binds to NGF, and the amino acid sequences of the heavy chain and light chain variable regions of the antibody. The NGF antibody and/or its antigen binding fragment provided by the invention has high affinity for NGF and can effectively block the binding between NGF receptor and NGF. This antibody and/or its antigen binding fragment can inhibit the binding activity of NGF and its receptor in vitro, and is suitable for the treatment of pain diseases which are related to the haughty expression or increased expression of NGF.

Abstract: Provided is a tetravalent homodimeric bispecific antibody molecule simultaneously targeting an immune effector cell antigen CD3 and a tumor-associated antigen, wherein the bispecific antibody molecule contains, in order from N-terminus to C-terminus, a first single chain Fv, a second single chain Fv and a Fc fragment; wherein the first single chain Fv can specifically bind to the tumor-associated antigen, the second single chain Fv can specifically bind to CD3, and the first and the second single chain Fvs are connected by a linker peptide, while the second single chain Fv and the Fc fragment are directly connected or connected by a linker peptide; and the Fc fragment does not have effector functions such as CDC, ADCC and ADCP.

Abstract: A method, a device, and a computer program product for managing a mobile terminal are provided. In one method, a first position of the mobile terminal at a first time point and a first signal quality of a mobile network signal of the mobile network at the first position are detected, respectively; a signal quality distribution of the mobile network signal in a surrounding area of the first position is acquired; a prediction of a second signal quality of a mobile network signal to be received by the mobile terminal at a second time point is obtained according to the signal quality distribution, the second time point being a future time point after the first time point; and according to the first signal quality and the prediction of the second signal quality, a second service quality to be provided to the mobile terminal at the second time point is determined.

Abstract: The present invention discloses a method and system for calculating SUV normalization coefficient in a SPECT quantitative tomographic image, comprises the following steps: a) averaging the anterior plain film image and posterior plain film image obtained by performing plain film scanning on a subject's whole body to get an average image, from which the area corresponding to the radioactive uptake site in the subject is segmented, b) correcting attenuation coefficient of human body, detection efficiency and acquisition time for each pixel value in the effective radioactive uptake area within said average image, c) averaging all the effective radioactive uptake area pointed at by said quantitative two-dimensional radioactive uptake activity image obtained in step b, and performing volume normalization and decay time correction to figure out the average radiopharmaceutical activity concentration absorbed in the subject.

Abstract: A TBM-mounted virtual reconstruction system and method for a tunnel surrounding rock structure, the method including: obtaining image information of surrounding rock; receiving the image information of the surrounding rock; transforming and splicing pictures taken at different angles, to form a complete image reflecting the surrounding rock; recognizing and describing a surrounding rock feature of the complete image, and transmitting the annotated image to a virtual reconstruction module; displaying the complete image with a description of the surrounding rock feature by using a virtual reality device, to reflect surrounding rock situations at different angles/different positions. This has the advantages of high equipment automation, not prolonging the construction time, not requiring the sketcher to enter the tunnel, precise surrounding rock feature parameters, and supporting remote control.

Abstract: A semiconductor device and method of formation are provided. The semiconductor device includes a substrate, a first active area over the substrate, a second active area over the substrate, a graphene channel between the first active area and the second active area, and a first in-plane gate. In some embodiments, the graphene channel, the first in-plane gate, the first active area, and the second active area include graphene. A method of forming the first in-plane gate, the first active area, the second active area, and the graphene channel from a single layer of graphene is also provided.