Abstract: A swimming cap including a main body including a first thickness; a rim portion, arranged around a rim of the swimming cap, including a second thickness; two overhang portions configured to be arranged symmetrically on either side of a spine of a wearer; and a recess configured to be arranged in proximity to the spine.

Abstract: The present invention relates generally to glucosidase inhibitors and their use in treating or preventing pulmonary diseases. In particular, the present invention is directed to use of ?-glucosidase inhibitors for treating or preventing bacterial or viral infections of the respiratory tract, including SARS-CoV-2.

Abstract: Provided are anti-CD8 antibodies that bind human CD8 and do not stimulate or inhibit the activation of CD8+ T cells. Also provided are nucleic acids encoding such anti-CD8 antibodies, vectors comprising such nucleic acids, host cells comprising same, and methods of making such anti-CD8 antibodies. Also provided are anti-CD8 antibodies conjugated to a detectable label. Provided are methods of using such anti-CD8 antibodies to detect CD8+ T cells in a subject, monitor disease progress in a subject having cancer, and monitor treatment progress in a subject having cancer.

Abstract: A technique for controlling access to one or more attractions is achieved using a number of access keys, each being issued to one or more users. An electronic queue management part manages a virtual queue in respect of each attraction and receives electronic requests for attraction access, each request relating to an access key and being for the users associated with it to access a particular attraction. Receipt of each request causes the respective users to be added to a corresponding virtual queue. A time at which each group of users reaches the front of the virtual queue and can access the attraction is determined. The users access the attractions by presenting an access key to an access control part, in communication with the electronic queue management part. Only a user presenting an access key at the correct time for accessing the attraction is allowed access to the attraction.

Abstract: The invention relates to a method and system for phosphate recovery from a stream such as waste flow, sewage or another sludge stream. The method comprises the steps of: providing an incoming stream comprising an initial amount of phosphate; dosing/controlling iron salt to the stream such that precipitates are formed in the stream, wherein the precipitates comprise vivianite like structures comprising more than 60% of the initial amount of phosphate in the incoming stream, and preferably also the steps of: separating the vivianite like structures from the stream; and recovering the phosphates from the separated vivianite like structures.

Abstract: The present disclosure describes an integrated circuit device that includes a digital signal processing (DSP) block. The DSP block that includes a plurality of columns of weight registers and a plurality of inputs configured to receive a first plurality of values and a second plurality of values. The first plurality of values is stored in the plurality of columns of weight registers after being received. Also, the first plurality of inputs, the second plurality of inputs, or both are derived from higher precision values. Additionally, the DSP block includes a plurality of multipliers configured to simultaneously multiply each value of the first plurality of values by each value of the second plurality of values.

Abstract: Aspects of the disclosure relate to a method of estimating a length of a queue associated with a resource within a venue. Images of the queue may be received, each image corresponding to a segment of the queue. A server may estimate a number of venue guests in the queue by: for each of a first subset of the images, estimating a number of pixels of the image that correspond to venue guests in the queue; and for each of a second subset of the images, detecting and counting individual venue guests visible in the image. A notification including the estimated number of venue guests in the queue, an estimated current wait time, and/or a time at which a venue guest joining the queue is permitted entry to the resource, may be sent to devices corresponding to venue guests.

Abstract: Provided are combination therapies comprising inavolisib (a.k.a. GDC-0077) and other HER2-targeted therapies (e.g., pertuzumab and trastuzumab) for the treatment of HER2-positive cancers; and methods of treating HER2 positive (HER2+) cancers in a patient (preferably a patient with a PIK3CA mutant breast cancer) comprising administering a therapeutically effective amount of inavolisib and a HER2-targeted therapy (e.g., trastuzumab, pertuzumab, or a combination of trastuzumab and pertuzumab).

Abstract: Systems, methods, and computer-readable media are provided for providing pose estimation in extended reality systems. An example method can include tracking, in a lower-power processing mode using a set of lower-power circuit elements on an integrated circuit, a position and orientation of a computing device during a lower-power processing period, the set of lower-power circuit elements including a static random-access memory (SRAM); suspending, based on a triggering event, the tracking in the lower-power processing mode; initiating a higher-power processing mode for tracking the position and orientation of the computing device during a higher-power processing period; and tracking, in the higher-power processing mode using a set of higher-power circuit elements on the integrated circuit and a dynamic random-access memory (DRAM), the position and orientation of the computing device during the higher-power processing period.

Abstract: Provided are anti-CD8 antibodies that bind human CD8 and do not stimulate or inhibit the activation of CD8+ T cells. Also provided are nucleic acids encoding such anti-CD8 antibodies, vectors comprising such nucleic acids, host cells comprising same, and methods of making such anti-CD8 antibodies. Also provided are anti-CD8 antibodies conjugated to a detectable label. Provided are methods of using such anti-CD8 antibodies to detect CD8+ T cells in a subject, monitor disease progress in a subject having cancer, and monitor treatment progress in a subject having cancer.

Abstract: A technique for controlling access to one or more attractions is achieved using a number of access keys, each being issued to one or more users. An electronic queue management part manages a virtual queue in respect of each attraction and receives electronic requests for attraction access, each request relating to an access key and being for the users associated with it to access a particular attraction. Receipt of each request causes the respective users to be added to a corresponding virtual queue. A time at which each group of users reaches the front of the virtual queue and can access the attraction is determined. The users access the attractions by presenting an access key to an access control part, in communication with the electronic queue management part. Only a user presenting an access key at the correct time for accessing the attraction is allowed access to the attraction.

Abstract: Aspects of the disclosure relate to a dynamic event securitization and neural network analysis system. A dynamic event inspection and securitization computing platform comprising at least one processor, a communication interface, and memory storing computer-readable instructions may securitize event data prior to authorizing execution of the event. A neural network event analysis computing platform comprising at least one processor, a communication interface, and memory storing computer-readable instructions may utilize a plurality of event analysis modules, a neural network, and a decision engine to analyze the risk level values of data sharing events. The dynamic event inspection and securitization computing platform may interface with the neural network event analysis computing platform by generating data securitization flags that may be utilized by the neural network event analysis computing platform to modify event analysis results generated by the event analysis modules.

Abstract: Media processing systems and techniques are described. A media processing system receives image data that represents an environment captured by an image sensor. The media processing system receives an indication of an object in the environment that is represented in the image data. The media processing system divides the image data into regions, including a first region and a second region. The object is represented in one of the plurality of regions. The media processing system modifies the image data to obscure the first region without obscuring the second region based on the object being represented in the one of the plurality of regions. The media processing system outputs the image data after modifying the image data. In some examples, the object is depicted in the first region and not the second region. In some examples, the object is depicted in the second region and not the first region.

Abstract: The present invention relates to deuterated and optionally detectably labeled compounds of formula (I) and formula (V): and salts thereof, wherein R1, R2, A, and X10-X19 have any of the values defined in the specification. Also included are pharmaceutical compositions comprising such compounds and salts, and methods of using such compounds and salts as imaging agents.

Abstract: Various embodiments include methods and devices for implementing a criterion aware cache replacement policy by a computing device. Embodiments may include updating a staling counter, writing a value of a local counter to a system cache in association with a location in the system cache for with data, in which the value of the local counter includes a value of the staling counter when (i.e., at the time) the associated data is written to the system cache, and using the value of the local counter of the associated data to determine whether the associated data is stale.

Abstract: A surgical system drape incudes: a sheath having an interior cavity sized to cover a portion of a surgical system manipulator; an adaptor coupled to the sheath and including a manipulator interface and an instrument interface, the manipulator interface configured to couple with a drive interface of the manipulator, the instrument interface being configured to couple with a drive interface of a surgical instrument mounted to the manipulator; and a fluid conduit coupled to the sheath and extending within the interior cavity of the sheath, the fluid conduit configured to receive a flow of cooling fluid at a fluid port and convey the fluid along the interior cavity of the sheath to cool a component of a portion of the manipulator.

Abstract: Systems and methods for endoscopic operations are described. For example, the disclosure provides mechanisms for sensing and controlling a field of view of an endoscope by determining a pose of the field of view using a first location and a second location, and controlling the pose of the field of view by moving at least one of: the first portion and the second portion. The first location is of a first portion of the endoscope and the second location is of a second portion of the endoscope. The endoscope comprises a flexible portion disposed between the first portion and the second portion. The first and second locations are defined by a configuration, relative to the endoscope, of an endoscope support and a cannula. The endoscope support configured to support the endoscope. A shaft of the endoscope is configured to extend through the cannula.

Abstract: Provided are CD8 binding agents comprising a VHH domain that specifically binds human CD8. Also provided are nucleic acids encoding such CD8 binding agents, vectors comprising such nucleic acids, host cells comprising same, and methods of making such CD8 binding agents. Also provided are CD8 binding agents having the VHH domain conjugated to a detectable label. Provided are methods of using such CD8 binding agents to detect CD8+ T cells, monitor disease progress, and monitor treatment progress in a subject having cancer, autoimmune disease or condition, transplant rejection or graft-versus-host disease.

Abstract: Systems, methods, and computer-readable media are provided for providing pose estimation in extended reality systems. An example method can include tracking, in a lower-power processing mode using a set of lower-power circuit elements on an integrated circuit, a position and orientation of a computing device during a lower-power processing period, the set of lower-power circuit elements including a static random-access memory (SRAM); suspending, based on a triggering event, the tracking in the lower-power processing mode; initiating a higher-power processing mode for tracking the position and orientation of the computing device during a higher-power processing period; and tracking, in the higher-power processing mode using a set of higher-power circuit elements on the integrated circuit and a dynamic random-access memory (DRAM), the position and orientation of the computing device during the higher-power processing period.

Abstract: A computer-implemented system and method for searching comprises, in an initial training phase, storing a plurality of user journeys in a stored journey database (SJDB), and storing a plurality of intents in a stored intents database (SIDB). The plurality of user journeys comprise a plurality of intents linked together by weighted links. In a first use phase, the method comprises determining a first intent of a first user or a second user, and modifying a first weighting of the weightings based on the first intent. In a second use phase, the method comprises receiving, from the second user, a second user question, determining a second intent from the second user question, and locating a user journey from the plurality of user journeys in the SJDB related to the second intent.