Abstract: An auto-injector for administering a dose of a liquid medicament (M) is present having a tubular chassis telescopable in a tubular case, a carrier subassembly comprising a tubular carrier slidably arranged relative to the chassis inside the case, where the carrier is adapted to contain a syringe with a hollow injection needle. The injector also has a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe, wherein the syringe is lockable for joint axial translation with the carrier. A control spring is arranged around the carrier for translating the carrier in a proximal direction (P) for insertion of the needle through the chassis into an injection site.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium for retrieving information from a server. Methods can include a server receiving a set of client-encrypted queries. The server identifies a set of server-encrypted decryption keys and transmits the set to the client device. The server receives a set of client-server-encrypted decryption keys that includes the set of server-encrypted decryption keys encrypted by the client device. The server also receives a set of client-encrypted/client-derived decryption keys that were derived by the client device. The server generates matching a map that specifies matches between the set of client-server-encrypted decryption keys and the set of client-encrypted/client-derived decryption keys. The server filters the set of client-encrypted queries using the map to create a set of filtered client-encrypted queries and generates a set of query results.

Abstract: An auto-injector for administering a dose of a liquid medicament (M) is present having a tubular chassis telescopable in a tubular case, a carrier subassembly comprising a tubular carrier slidably arranged relative to the chassis inside the case, where the carrier is adapted to contain a syringe with a hollow injection needle. The injector also has a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe, wherein the syringe is lockable for joint axial translation with the carrier. A control spring is arranged around the carrier for translating the carrier in a proximal direction (P) for insertion of the needle through the chassis into an injection site.

Abstract: This disclosure provides methods for treating a subject afflicted with a tumor derived from a renal cell carcinoma. The methods comprise administering a first dose to a subject of an anti-PD-1 antibody or antigen-binding portion thereof and/or an anti-PD-L1 antibody or antigen-binding portion thereof, and administering a second dose to the subject, wherein the subject exhibited differential expression in one or more biomarker genes, e.g., CTLA-4, TIGIT, and/or PD-L2, following administration of the first dose.

Abstract: An auto-injector for administering a dose of a liquid medicament (M) is present having a tubular chassis telescopable in a tubular case, a carrier subassembly comprising a tubular carrier slidably arranged relative to the chassis inside the case, where the carrier is adapted to contain a syringe with a hollow injection needle. The injector also has a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe, wherein the syringe is lockable for joint axial translation with the carrier. A control spring is arranged around the carrier for translating the carrier in a proximal direction (P) for insertion of the needle through the chassis into an injection site.

Abstract: A layer destacking system for destacking layer from stacked layer pallet load, including layer seating platform configured to seat the destacked layer on layer seating platform, conveying surface with conveyance traverse direction traverses the seated destacked layer off layer seating platform, slip sheet detection sensor coupled to layer seating platform and arranged to sense slip sheet in contact with seated destacked layer on uppermost surface and bottom surface of seated destacked layer, slip sheet pickup removal mechanism extending over layer seating platform configured to engage, above layer seating platform, slip sheet contacting one uppermost surface and bottom surface of seated destacked layer controller communicably coupled to slip sheet detection sensor to receive signal from slip sheet detection sensor identifying presence of slip sheet, controller is operably connected to slip sheet pickup removal mechanism to actuate slip sheet pickup removal mechanism engaging slip sheet contacting one uppermos

Abstract: An auto-injector for administering a dose of a liquid medicament (M) is present having a tubular chassis telescopable in a tubular case, a carrier subassembly comprising a tubular carrier slidably arranged relative to the chassis inside the case, where the carrier is adapted to contain a syringe with a hollow injection needle. The injector also has a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe, wherein the syringe is lockable for joint axial translation with the carrier. A control spring is arranged around the carrier for translating the carrier in a proximal direction (P) for insertion of the needle through the chassis into an injection site.

Abstract: Collet chuck having a plurality of jaws which are radially movable with respect to one another and which, with their clamping faces, form a common receptacle for guiding a rod that is to be machined in a lathe, characterized by a blind hole which is routed in at least one jaw from the outer face, opposite the clamping face of the jaw, in the direction of the clamping face, with a blind-hole bottom which is delimited on the one hand by the clamping face and on the other hand by the blind hole and which, through wear of the clamping face, is configured to effect the formation of a through-hole indicating the wear of the collet chuck.

Abstract: Systems and methods for importing documents are described. An input image is received and preprocessed. OCR and/or page segmentation and chapter detection are performed. Special-case processing is performed for lists, tables, free text, and other categories. Anaphora analysis, stemming, lemmatization, and relationship detection are performed. A genealogical tree is generated, augmented, or merged based on the extracted entities and relationships.

Abstract: A method for determining a measurement setting for measuring a parameter of interest from a target structure on a substrate. The method includes: obtaining first position difference data describing a difference between a position of a first representative target structure position and a position of one or more first features relating to product structure; obtaining optical metrology data relating to optical measurements of the target structure and further relating to a plurality of different measurement settings; and determining the measurement setting from the first position difference data and the optical metrology data such that a measured feature position value obtained from an optical measurement of the target structure using the determined measurement setting is better correlated to a position of the one or more first features.

Abstract: A computer-implemented method is provided. The method includes generating an augmented reality environment, determining a number of virtual avatars requiring an avatar space within said augmented reality environment, determining a number of physical avatar spaces that are available for occupation within the augmented reality environment, comparing the number of virtual avatars requiring an avatar space to the number of available physical avatar spaces and, when the number of virtual avatars requiring an avatar space within the augmented reality environment is less than or equal to the number of available physical avatar spaces, assigning a different available physical avatar space to each virtual avatar.

Abstract: A transistor stack can include a combination of floating and body tied devices. Improved performance of the RF amplifier can be obtained by using a single body tied device as the input transistor of the stack, or as the output transistor of the stack, while other transistors of the stack are floating transistors. Transient response of the RF amplifier can be improved by using all body tied devices in the stack.

Abstract: Disclosed are techniques for environment sensing. In an aspect, a transmitter base station determines a configuration for a radio frequency (RF) sensing signal, the configuration determined based at least in part on coordination among a plurality of base stations, and transmits the RF sensing signal to at least one receiver base station based on the configuration. In an aspect, a receiver base station receives a configuration for an RF sensing signal, the configuration determined based at least in part on coordination among a plurality of base stations, receives, from at least one transmitter base station, the RF sensing signal, and detects at least one target object based, at least in part, on reception of the RF sensing signal.

Abstract: The disclosure relates to operating a wind turbine generator during heating operation that includes a rotor and a stator. The stator includes a first three-phase system with three first drivetrains and a second three-phase system with three second drivetrains. The rotor is configured to generate a magnetic field and inject an electric current into the first and second three-phase systems during a rotation with the magnetic field. The first three-phase system includes a first switch for short-circuiting the first drivetrains in a closed state and idling them in an open state. The second three-phase system includes a second switch for short-circuiting the second drivetrains in a closed state and idling them in an open state. The heating operation includes a first phase in which the first switch is switched to the closed state and the second switch is switched to the open state, or vice-versa.

Abstract: With the present inventive concept there is provided a system comprising: a test card receiver configured to receive a test card, wherein the test card comprises a sample portion having a first side and a second side opposite the first side, wherein the sample portion of the test card is configured to hold a sample for PCR; a temperature adjuster configured to adjust a temperature of the sample portion of the test card over a plurality of temperature cycles, wherein each temperature cycle is between a first temperature and a second temperature different than the first temperature, wherein the temperature adjuster comprises a surface configured to be in contact with the first side of the sample portion of the test card; wherein the test card receiver comprises a spring member configured to push the sample portion of the test card towards the surface of the temperature adjuster; and a monitoring arrangement configured to monitor the sample portion of the test card over the plurality of temperature cycles, the m

Abstract: A cooling system is disclosed. The cooling system can include a flow path including a main path and a secondary path. The secondary path can have an inlet and an outlet. The inlet can be in fluid communication with a first portion of the main path and the outlet can be in fluid communication with a second portion of the main path. The cooling system can include a passive fluid flow controller. The passive fluid flow controller can be positioned in the main path between the first portion and the second portion. The passive fluid flow controller can adjust an amount of a coolant that is routed to the secondary path from the main path through the inlet of the secondary path. The passive fluid flow controller can impede a particle from entering the secondary path via the inlet of the secondary path.

Abstract: Guide vane for a guide wheel of a pump or turbine having a guide vane body with two end faces, a guide vane leading edge, a guide vane trailing edge, and first and second flow-guiding side faces connecting the vane leading and trailing edges and forming different flow profiles along an axial extension. Each flow profile has a chord, a mean camber line, and a mean camber curve end angle between the mean camber line and the chord at the vane trailing edge. The guide vane is mounted to rotate about an axis of rotation defined by two pivot pins. Along the axial extension, the guide vane has at least one flow profile with a positive mean camber curve end angle and at least one flow profile with a negative mean camber curve end angle. The guide vane leading edge is tilted relative to the axis of rotation.

Abstract: An auto-injector for administering a dose of a liquid medicament (M) is present having a tubular chassis telescopable in a tubular case, a carrier subassembly comprising a tubular carrier slidably arranged relative to the chassis inside the case, where the carrier is adapted to contain a syringe with a hollow injection needle. The injector also has a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe, wherein the syringe is lockable for joint axial translation with the carrier. A control spring is arranged around the carrier for translating the carrier in a proximal direction (P) for insertion of the needle through the chassis into an injection site.

Abstract: A reconfigurable grading blade attachment for a work machine includes an attachment frame, a pivot beam extending transversely to the frame length, a left stabilizer wheel assembly pivotally coupled to the left portion of the pivot beam, a right stabilizer wheel assembly pivotally coupled to a right portion of the pivot beam, a center mount, a left hydraulic actuator pivotally coupled to the left portion of the pivot beam, a right hydraulic actuator pivotally coupled to the right portion of the pivot beam, and a grading blade extending transversely to the length of the work machine frame. Retraction of the left hydraulic actuator rotates the left stabilizer wheel assembly upwards about the left wheel lift axis. Retraction of the right hydraulic actuator rotates the right stabilizer wheel assembly upwards about the right wheel lift axis.

Abstract: A positive-logic FET switch stack that does not require a negative bias voltage, exhibits high isolation and low insertion/mismatch loss, and may withstand high RF voltages. Embodiments include a FET stack comprising series-coupled positive-logic FETs (i.e., FETs not requiring a negative voltage supply to turn OFF), series-coupled on at least one end by an “end-cap” FET of a type that turns OFF when its VGS is zero volts. The one or more end-cap FETs provide a selectable capacitive DC blocking function or a resistive signal path. Embodiments include a stack of FETs of only the zero VGS type, or a mix of positive-logic and zero VGS type FETs with end-cap FETs of the zero VGS type. Some embodiments withstand high RF voltages by including combinations of series or parallel coupled resistor ladders for the FET gate resistors, drain-source resistors, body charge control resistors, and one or more AC coupling modules.