Abstract: The present invention relates to compounds of formula (I): or pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising these compounds, as well as methods and uses of these compounds in the treatment of diseases.

Abstract: An inkjet printer has a print assembly and a print material feed system comprising a first circulation circuit and a second circulation circuit, the first circulation circuit fluidly coupled between the second circulation circuit and the print assembly.

Abstract: Determining job postings posted by one entity of an enterprise that are re-classifiable with respect to another entity of the enterprise. Computer systems and/or computer implemented methods use one or more reclassification analyses to compare an enterprise's active job postings with operations descriptions of entities of the job postings other than the entity that posted the job posting. A report and/or an alert can be generated when there is sufficient overlap between a job posting and an entity that did not post the job posting, indicating that the job posting is likely re-classifiable.

Abstract: Aspects of the disclosure are directed toward intelligently selecting the operating parameters of wireless access points (WAPs) deployed in a wireless environment so as to minimize or at least reduce interference in that wireless environment. A WAP may continually measure characteristics of wireless channels used in the wireless environment and obtain measurements of channel metrics for those channels. The WAP analyzes the channel metric history to identify correlations between the channel metric measurements and various timeframes and selects one or more of its operating parameters based on the channel metric history and the correlations identified.

Abstract: Decommissioned wind turbine rotor blades are repurposed in alternative aerodynamic configurations with reduced or differentiated mechanical stress and cost-of-operation modalities. In one exemplary configuration, repurposed blades are affixed on a differentiated axial and gravitational orientation. In another exemplary configuration, the repurposed blades are longitudinally segmented. In yet another configuration, the blades are multiplied in a configuration designed for slower rotation. Additional alternative stress-differentiated and cost-of-operation configurations are disclosed herein. In a method of manufacture, repurposed wind turbine blades are provided in conjunction with blade configurations adapted to differentiated stress profiles.

Abstract: According to an aspect, an inflatable penile prosthesis includes a fluid reservoir configured to hold fluid, an inflatable member, and a pump assembly configured to transfer the fluid from the fluid reservoir to the inflatable member during an inflation cycle. The pump assembly includes a first pump configured to inject the fluid into the inflatable member according to a first flow rate, and a second pump configured to inject fluid into the inflatable member according to a second flow rate, where the second flow rate is less than the first flow rate.

Abstract: Methods and systems of PFAS destruction in water containing nitrate. The methods and systems include filtering water containing PFAS and nitrate through a membrane selective for PFAS to obtain a membrane reject containing PFAS and nitrate and a filtrate containing nitrate, forming a treatment solution using the membrane reject including diluting the membrane reject and combining the membrane reject with a photosensitizer, a sulfite salt, and a sufficient amount of base such that the treatment solution has a pH of about 10 or more, and irradiating the treatment solution with UV light in a photoreactor to destroy a portion of the PFAS. Before dilution, a concentration of PFAS in the membrane reject may be between about 3 times and about 20 times greater than before the filtering step. Dilution of the membrane reject may include between about a 3 and about a 20 times dilution.

Abstract: Wellbore synthesis techniques are disclosed suitable for use in geothermal applications. Embodiments are provided where open hole drilled wellbores are sealed while drilling in sequenced operations with utilization of phase change materials to form an impervious layer at the wellbore/formation interface in high temperature applications. The techniques may be chemical, thermal, mechanical, biological and are fully intended to irreversibly damage the formation in terms of the permeability thereof. With the permeability negated, the wellbore may be used to create a closed loop surface to surface geothermal well operable in the absence of well casing for heat transfer surfaces for maximizing thermal transfer to a circulating working fluid. Formulations for the working and drilling fluids are disclosed.

Abstract: This disclosure relates to a medical infusion device having a reservoir for holding a liquid medicament, a cannula assembly, a fluid line, a drive mechanism, a dispensing member for dispensing medicament from reservoir through the fluid line and the cannula assembly, and a leakage determining module. For a more convenient determination of leakage of liquid medicament, the leakage determining module includes an electronic probe for receiving odor molecules and/or flavor molecules of the liquid medicament and the leakage determining module has evaluation electronics to determine presence of odor and/or flavor of the liquid medicament based on readings of the electronic probe.

Abstract: The Music Card is a ready for purchase plastic card that directs customers to access digital full-length albums, singles, or EP' by specific artists; functioning like a vinyl album, CD, Cassettes, by showing in the front; the artist name, album cover, and recording/distribution company. On the back, it shows song titles from the album, UPC Barcode, Explicit Content Warning label, purchase price recording/distribution label, how to access album digitally and scratch off download code. It is used like a prepaid gift card and stores information available for download on all internet connected electronic devices. Manually type in URL, or scan QR code under scratch off, proceed to online checkout. When code is entered, the price will mark down. After completion, the download link and sales notification will go to the customer's email available for only 30 days.

Abstract: A space efficient automated processing system for processing objects is disclosed. The processing system includes an input conveyance system for moving objects from an input area in at least an input conveyance vector that includes an input conveyance horizontal direction component and an input conveyance vertical direction component, a perception system for receiving objects from the input conveyance system and for providing perception data regarding an object, a primary transport system for receiving the object from the perception system and for providing transport of the object along at least a primary transport vector including an primary transport horizontal component and a primary transport vertical component that is generally opposite the input conveyance horizontal direction component, and at least two secondary transport systems, each of which receives the object from the primary transport system and moves the object in either of reciprocal directions.

Abstract: The disclosed technology includes a support system for an optical sighting device of a bow. The support system includes a support structure configured to attach to a bow and an elevation assembly configured to move along an elevation direction relative to the support structure. The support structure can include an elevation actuator configured to cause the elevation assembly to move along the elevation direction when the elevation actuator is actuated and a windage assembly configured to move along a windage direction relative to the support structure. The windage direction can be approximately perpendicular to the elevation direction. The support structure can further include a windage actuator configured to cause the windage assembly to move along the windage direction when the windage actuator is actuated. The windage actuator can be disposed at least partially in the elevation actuator.

Abstract: In some aspects, a non-transitory computer readable medium is disclosed that has an application stored thereon that when executed by a processor of an electronic device causes the processor to perform a process. The process can include receiving motion data from a motion sensor, the motion data being indicative of motion by a user while wearing the motion sensor. The process can also include transmitting the motion data to a server, receiving from the server a time that the motion data indicates a foot of the user experienced a loading force which risked adversely impacting an existing foot ulcer or causing a new foot ulcer, determining a geographic location of the motion sensor at the time that the foot experienced the loading force, displaying the time and the geographic location, and requesting that the user identify an activity engaged in by the user at the time and the geographic location.

Abstract: Systems, devices, and methods for an unmanned aerial vehicle (UAV); a trace gas sensor disposed on the UAV, where the gas sensor is configured to measure a gas point concentration; a wind sensor, where the wind sensor is configured to determine a discrete wind vector corresponding to the gas point concentration measurement; and where the discrete wind vector and gas point concentration measurement are acquired substantially concurrently and co-locally.

Abstract: A method of processing objects using a programmable motion device is disclosed. The method includes the steps of perceiving identifying indicia representative of an identity of a plurality of objects and directing the plurality of objects toward an input area from at least one input conveyance system, acquiring an object from the plurality of objects at the input area using an end effector of the programmable motion device, and moving the acquired object toward an identified processing location using the programmable motion device, said identified processing location being associated with the identifying indicia and said identified processing location being provided as one of a plurality of processing locations that are radially spaced from the programmable motion device.

Abstract: A chip-based optical detection system for detecting a target component in a liquid sample is provided. The system comprises a fluid pathway disposed in an interior volume of the chip; an inlet fluidically connecting an external surface of the chip to the fluid pathway; an optical element at least partially defining the fluid pathway; and a flow controller configured to control a flow of the liquid sample through the fluid pathway. One or more capture components are immobilised on the optical element, one or more detection reagents are provided in a proximity of the capture components, and the flow controller is configured to control the flow of the liquid sample along the fluid pathway such that the detection reagents are brought into contact with the capture components via diffusion.

Abstract: Techniques for improved peer-to-peer communication are provided. A first peer-to-peer device associated with a first wireless AP, may transmit a first peer-to-peer transmission schedule to a second wireless AP, where the first peer-to-peer transmission schedule was accepted by the first wireless AP. In response to receiving an acceptance from the second wireless AP, the first wireless AP transitions from to the second wireless AP. The first peer-to-peer device performs peer-to-peer communication in accordance with the first peer-to-peer transmission schedule.

Abstract: A vertebral body replacement device, dimensioned for implantation between a first and second vertebral bone is described. The vertebral body replacement device includes a superior endcap, an inferior endcap and a central core between the superior and inferior endcaps. The vertebral body replacement device further includes a fusion aperture extending through the superior and inferior endcaps and central core. The vertebral body replacement device is made of radiolucent material and can be implanted from a lateral or anterior approach to the spine.

Abstract: A track of a vertically stacking door includes a vertical track, a first curved track portion, a second curved track portion, a first horizontal track portion coupled to the first curved track portion, and a second horizontal track portion coupled to the second curved track portion. The first curved track portion and the second curved track portion are split off from the vertical track and the first curved track portion and the second curved track portion each comprises multiple radii of curvature.

Abstract: According to an aspect, an implantable device includes a fluid reservoir configured to be implanted in a body of a patient at a first location, an inflatable member configured to be implanted in the body of the patient at a second location, and a pump assembly configured to be implanted in the body of the patient at a third location. The pump assembly is configured to transfer fluid from the fluid reservoir to the inflatable member in response to the implantable device being in an inflation mode, and the pump assembly configured to transfer the fluid from the inflatable member to the fluid reservoir in response to the implantable device being in a deflation mode. The pump assembly includes an electronic control module, an electronically powered pump, a first valve, and a second valve. The electronic control module is configured to activate or deactivate the electronically powered pump.