Patents by Inventor Son V. Nguyen
Son V. Nguyen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20210401571Abstract: A prosthetic heart valve includes an annular frame that has an inflow end and an outflow end and is radially compressible and expandable between a radially compressed configuration and a radially expanded configuration. The prosthetic heart valve further includes a leaflet structure positioned within the frame and secured thereto, and an outer sealing member mounted outside of the frame and adapted to seal against surrounding tissue when the prosthetic heart valve is implanted within a native heart valve annulus of a patient. The sealing member can include a mesh layer and pile layer comprising a plurality of pile yarns extending outwardly from the mesh layer.Type: ApplicationFiled: August 31, 2018Publication date: December 30, 2021Inventors: Lien Huong Thi Hoang, Son V. Nguyen, Hien Tran Ngo, Vivian Tran, Russell T. Joseph, Dinesh L. Sirimanne, Kevin D. Rupp, Diana Nguyen-Thien-Nhon
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Publication number: 20210386543Abstract: Embodiments of a radially collapsible and expandable prosthetic heart valve and method for crimping the prosthetic heart valve are disclosed. A method of radially compressing a prosthetic valve can include partially inserting the valve while in a radially expanded configuration into a crimping device comprising crimper jaws, wherein a portion of the valve comprising an outer skirt extends outside of the crimper jaws. The method can further include crimping the valve to a first partially collapsed configuration, further inserting the valve into the crimping device, such that the outer skirt is between the crimper jaws, and crimping the valve to a second partially collapsed configuration, wherein a diameter of the valve is smaller in the second partially collapsed configuration than in the first partially collapsed configuration.Type: ApplicationFiled: August 27, 2021Publication date: December 16, 2021Applicant: Edwards Lifesciences CorporationInventors: Tamir S. Levi, Ron Sharoni, Elena Sherman, Oren H. Wintner, Kevin D. Rupp, Son V. Nguyen, Ajay Chadha, Jeff Lindstrom
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Patent number: 11191638Abstract: Expandable docking stations for docking an expandable valve can include a valve seat, one or more sealing portions, and/or one or more retaining portions. The valve seat can be unexpandable or substantially unexpandable beyond a deployed size. The one or more sealing portions can be connected to the valve seat and extend radially outward of the valve seat. The one or more sealing portions can be constructed to expand outward of the valve seat and provide a seal over a range of sizes. The one or more retaining portions can be connected to the one or more sealing portions. The one or more retaining portions are configured to retain the docking station at a deployed position.Type: GrantFiled: March 1, 2019Date of Patent: December 7, 2021Assignee: Edwards Lifesciences CorporationInventors: Dustin P. Armer, Michael D. Franklin, Sergio Delgado, Abhijeet Joshi, Dinesh L. Sirimanne, Russell T. Joseph, Eason Michael Abbott, Tram Ngoc Nguyen, Son V. Nguyen, Hien Tran Ngo, Vivian Tran, Charles L. Bowman, Stanton J. Rowe
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Patent number: 11186911Abstract: A deposition apparatus for depositing a material on a substrate is provided. The deposition apparatus has a processing chamber defining a processing space in which the substrate is arranged, an ultraviolet radiation assembly configured to emit ultraviolet radiation and a microwave radiation assembly configured to emit microwave radiation into an excitation space that can be the same as the processing space, and a gas feed assembly configured to feed a precursor gas into the processing space and a reactive gas into the excitation space. The ultraviolet radiation assembly and the microwave radiation assembly are operated in combination to excite the reactive gas in the excitation space. The material is deposited on the substrate from the reaction of the excited reactive gas and the precursor gas. A method for using the deposition apparatus to deposit a material on a substrate is provided.Type: GrantFiled: August 19, 2019Date of Patent: November 30, 2021Assignee: International Business Machines CorporationInventors: Alfred Grill, Son V. Nguyen, Deepika Priyadarshini
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Publication number: 20210353408Abstract: A hybrid heart valve prosthesis that can be quickly and easily implanted during a surgical procedure is provided. The hybrid heart valve includes a substantially non-expandable, non-compressible prosthetic valve member having a peripheral sealing ring and an expandable stent frame projecting from an inflow end, thereby enabling attachment to the annulus without sutures. The stent frame may be plastically-expandable and may have a thin fabric layer covering its entirety as well as secondary sealing structures around its periphery to prevent paravalvular leaking. Other sealing solutions include interactive steps at the time of valve implant to establish seals around the stent and especially between the stent and the sealing ring of the valve member.Type: ApplicationFiled: July 30, 2021Publication date: November 18, 2021Inventors: Harvey H. Chen, Son V. Nguyen, Devin D. Nguyen, Diana Marie George, August R. Yambao, Jyoti B. Rao, Alyssa E. Kornswiet, Lisong Ai, Stephen W. Tang, Edward Romero, Kevin K. Dang, Meena Francis, Louis A. Campbell, Grace Myong Kim
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Publication number: 20210322163Abstract: A prosthetic heart valve includes a frame, a valvular structure, and a skirt. The frame is movable between collapsed and expanded configurations and includes struts disposed between inflow and outflow ends, apices disposed at the inflow end formed by intersections of two or more struts, and junctions disposed between the apices and the outflow end and formed by intersections of two or more struts. The apices are circumferentially offset from the junctions. The valvular structure is positioned within and secured to the frame. The skirt is secured to the frame and includes a first edge portion and a second edge portion. The first edge portion is secured to the frame at the apices. The second edge portion is secured to the frame at the junctions. The skirt is configured to retract inwardly between the apices when the frame is moved from the radially expanded configuration to the radially collapsed configuration.Type: ApplicationFiled: June 30, 2021Publication date: October 21, 2021Applicant: Edwards Lifesciences CorporationInventors: Diana Nguyen-Thien-Nhon, Timothy A. Geiser, Larry L. Wood, Dinesh L. Sirimanne, Son V. Nguyen, Tamir S. Levi, Nikolay Gurovich, Michael Bukin
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Patent number: 11123184Abstract: Embodiments of a radially collapsible and expandable prosthetic heart valve are disclosed. A valve frame can have a tapered profile when mounted on a delivery shaft, with an inflow end portion having a smaller diameter than an outflow end portion. The valve can comprise generally V-shaped leaflets, reducing material within the inflow end of the frame. An outer skirt can be secured to the outside of the inflow end portion of the frame, the outer skirt having longitudinal slack when the valve is expanded and lying flat against the frame when the valve is collapsed. A diagonally woven inner skirt can elongate axially with the frame. Side tabs of adjacent leaflets can extend through and be secured to window frame portions of the frame to form commissures. The window frame portions can be depressed radially inward relative to surrounding frame portions when the valve is crimped onto a delivery shaft.Type: GrantFiled: October 18, 2019Date of Patent: September 21, 2021Assignee: Edwards Lifesciences CorporationInventors: Tamir S. Levi, Son V. Nguyen, Netanel Benichou, David Maimon, Ziv Yohanan, Nikolay Gurovich, Bella Felsen, Larisa Dadonkina, Ron Sharoni, Elena Sherman
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Patent number: 11103345Abstract: Embodiments of a radially collapsible and expandable prosthetic heart valve are disclosed. The prosthetic valve can comprise an annular frame, leaflets, an inner skirt, and an outer skirt. The outer skirt can be secured to the outside of the inflow end portion of the frame, the outer skirt having longitudinal slack that buckles outward radially when the valve is in the expanded configuration and which lies flat when the valve is in the collapsed configuration. In some embodiments, the outer skirt is stiffer in the axial direction of the valve than in the circumferential direction of the valve. In additional embodiments, the outer skirt comprises a self-expandable fabric comprising fibers made of a shape memory material having a shape memory set to enhance the radially outward buckling of the outer skirt. Methods of crimping such valves to a collapsed or partially collapsed configuration are also disclosed.Type: GrantFiled: January 30, 2019Date of Patent: August 31, 2021Assignee: Edwards Lifesciences CorporationInventors: Tamir S. Levi, Ron Sharoni, Elena Sherman, Oren H. Wintner, Kevin D. Rupp, Son V. Nguyen, Ajay Chadha, Jeff Lindstrom
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Patent number: 11066748Abstract: A deposition apparatus for depositing a material on a substrate is provided. The deposition apparatus has a processing chamber defining a processing space in which the substrate is arranged, an ultraviolet radiation assembly configured to emit ultraviolet radiation and a microwave radiation assembly configured to emit microwave radiation into an excitation space that can be the same as the processing space, and a gas feed assembly configured to feed a precursor gas into the processing space and a reactive gas into the excitation space. The ultraviolet radiation assembly and the microwave radiation assembly are operated in combination to excite the reactive gas in the excitation space. The material is deposited on the substrate from the reaction of the excited reactive gas and the precursor gas. A method for using the deposition apparatus to deposit a material on a substrate is provided.Type: GrantFiled: August 19, 2019Date of Patent: July 20, 2021Assignee: International Business Machines CorporationInventors: Alfred Grill, Son V. Nguyen, Deepika Priyadarshini
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Patent number: 11051937Abstract: An implantable prosthetic valve can comprise an annular frame comprising an inflow end and an outflow end and being radially collapsible and expandable between a radially collapsed configuration and a radially expanded configuration, the frame defining an axial direction extending from the inflow end to the outflow end, a leaflet structure positioned within the frame and secured thereto, and an annular outer skirt positioned around an outer surface of the frame, wherein the outer skirt comprises an inflow edge secured to the frame at a first location, an outflow edge comprising a plurality of alternating projections and notches, wherein the projections are secured to the frame at a second location, and the notches are not directly secured to the frame, an intermediate portion between the inflow edge and the outflow edge that comprises a plurality of openings.Type: GrantFiled: May 22, 2018Date of Patent: July 6, 2021Assignee: Edwards Lifesciences CorporationInventors: Diana Nguyen-Thien-Nhon, Timothy A. Geiser, Larry L. Wood, Dinesh L. Sirimanne, Son V. Nguyen, Tamir S. Levi, Nikolay Gurovich, Michael Bukin
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Publication number: 20210196457Abstract: A prosthetic heart valve assembly includes a self-expandable stent having an inlet end and an outlet end and a passageway extending therethrough. The stent includes a plurality of rows of prongs on the outer surface of the stent. A valve portion comprising a plurality of leaflets is positioned within the passageway for permitting blood to flow through the passageway from the inlet end to the outlet end while blocking flow in the opposite direction. The stent further includes a flared upper portion shaped for placement along a supra-annular surface of an annulus for preventing downward migration of the prosthetic valve assembly into a ventricle. Each of the prongs has a tip pointing toward the inlet end for penetrating surrounding tissue and preventing upward migration of the prosthetic heart valve assembly toward an atrium.Type: ApplicationFiled: March 16, 2021Publication date: July 1, 2021Applicant: Edwards Lifesciences CorporationInventors: Stanton J. Rowe, Mark Chau, Son V. Nguyen
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Patent number: 11008676Abstract: A textured fabric for an implantable bioprosthesis is provided. The textured fabric can include a woven base layer and a plurality of loops projecting from the woven base layer. The plurality of loops are formed from a composite core-sheath yarn. The core can be made of a material that is different from the sheath. The core material can be selected to impart strength and resiliency to bending and the sheath material can be selected to impart a larger surface area or texture that facilitates cellular or tissue in-growth.Type: GrantFiled: December 14, 2016Date of Patent: May 18, 2021Assignee: Edwards Lifesciences CorporationInventors: Ajay Chadha, Son V. Nguyen, Kevin D. Rupp
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Publication number: 20210137675Abstract: An implantable prosthetic valve can include a radially expandable and collapsible annular frame having an inflow end and an outflow end. A leaflet structure can be positioned within the frame. An annular inner skirt can be positioned around an inner surface of the frame, wherein the inner skirt includes an outflow edge portion secured to the frame and an inflow edge portion secured to the frame. An outer skirt can be positioned around the outer surface of the frame, wherein the outer skirt comprises an outflow edge portion secured to the frame and an inflow edge portion that is secured to the inflow edge portion of the inner skirt, wherein the inner and outer skirts are configured such that when the prosthetic valve is implanted, antegrade blood can flow through a space between the inflow edge portion of the inner skirt and the inflow edge portion of the outer skirt.Type: ApplicationFiled: January 22, 2021Publication date: May 13, 2021Inventors: Tamir S. Levi, Son V. Nguyen
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Patent number: 10971675Abstract: Magnetic tunnel junction pillars are encapsulated by an oxidized diffusion barrier layer. Oxygen within the encapsulating material is used to oxidize metallic residue outside the pillars, converting the residue to a non-conductive material such as a metal oxide or metal oxynitride. Selective deposition of manganese on the metal layers of the pillars can be followed by oxidation of the manganese to form a manganese oxide diffusion barrier. Alternatively, manganese deposition can be followed by deposition of silicon dioxide and subsequent annealing to form a manganese silicate diffusion barrier.Type: GrantFiled: September 27, 2019Date of Patent: April 6, 2021Assignee: International Business Machines CorporationInventors: Son V. Nguyen, Alexander Reznicek, Donald F. Canaperi
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Publication number: 20210093450Abstract: Embodiments of a radially collapsible and expandable prosthetic heart valve are disclosed. A valve frame can have a tapered profile when mounted on a delivery shaft, with an inflow end portion having a smaller diameter than an outflow end portion. The valve can comprise generally V-shaped leaflets, reducing material within the inflow end of the frame. An outer skirt can be secured to the outside of the inflow end portion of the frame, the outer skirt having longitudinal slack when the valve is expanded and lying flat against the frame when the valve is collapsed. A diagonally woven inner skirt can elongate axially with the frame. Side tabs of adjacent leaflets can extend through and be secured to window frame portions of the frame to form commissures. The window frame portions can be depressed radially inward relative to surrounding frame portions when the valve is crimped onto a delivery shaft.Type: ApplicationFiled: November 25, 2020Publication date: April 1, 2021Applicant: Edwards Lifesciences CorporationInventors: Tamir S. Levi, Son V. Nguyen, Netanel Benichou, David Maimon, Ziv Yohanan, Nikolay Gurovich, Bella Felsen, Larisa Dadonkina, Ron Sharoni, Elena Sherman
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Patent number: 10952846Abstract: A deficient native mitral valve is treated by implanting a prosthetic mitral valve assembly valve in a patient's heart. The prosthetic mitral valve assembly includes a stent having a flared upper portion, an intermediate portion, and a lower portion. The diameter at the inflow end of the stent is larger than at the outflow end. The prosthetic mitral valve assembly also includes a valve portion formed with pericardial tissue leaflets. A tether has a first end attached to the stent and a second end attached to an anchor. The tether extends through a wall of the left ventricle and the tissue anchor is placed outside the left ventricle. After implantation, the flared upper portion resists movement in the downstream direction and the tether resists movement in the upstream direction for securing the prosthetic mitral valve assembly in the native mitral valve.Type: GrantFiled: January 2, 2019Date of Patent: March 23, 2021Assignee: Edwards Lifesciences CorporationInventors: Stanton J. Rowe, Mark Chau, Son V. Nguyen
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Publication number: 20210022852Abstract: A docking device includes a hollow cylindrical body portion having an internal surface and an outer surface. The hollow cylindrical body portion is formed of a three-dimensional (3D) woven fabric comprising a plurality of different types of fibers.Type: ApplicationFiled: October 15, 2020Publication date: January 28, 2021Applicant: Edwards Lifesciences CorporationInventors: Son V. Nguyen, Kevin D. Rupp, Ajay Chadha, Jeff Lindstrom
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Patent number: 10898319Abstract: An implantable prosthetic valve can include a radially expandable and collapsible annular frame having an inflow end and an outflow end. A leaflet structure can be positioned within the frame. An annular inner skirt can be positioned around an inner surface of the frame, wherein the inner skirt includes an outflow edge portion secured to the frame and an inflow edge portion that wraps around the inflow end of the frame and extends at least partially along an outer surface of the frame, with the inflow edge portion being secured to the frame. An outer skirt can be positioned around the outer surface of the frame, wherein the outer skirt comprises an outflow edge portion secured to the frame and an inwardly folded inflow edge portion that is secured to the inflow edge portion of the inner skirt.Type: GrantFiled: August 13, 2018Date of Patent: January 26, 2021Assignee: Edwards Lifesciences CorporationInventors: Tamir S. Levi, Son V. Nguyen
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Publication number: 20200405482Abstract: A prosthetic heart valve comprises a radially collapsible and expandable annular frame and a leaflet structure comprising three leaflets. Each leaflet has an upper edge portion, a curved lower edge portion and two side flaps, wherein each side flap is connected to an adjacent side flap of another leaflet to form commissures of the leaflet structure, with each commissure being attached to the frame. An annular inner sleeve comprises three U-shaped portions positioned along the curved lower edge portions of the leaflets. An annular outer sleeve extends around are outer surface of the frame, wherein the outer sleeve is made of pericardium. The frame is made of Nitinol and the prosthetic valve can be radially crimped to a radially collapsed configuration inside a sheath for delivery into a patient's body and self-expand to a radially expanded configuration when released from the sheath inside the patient's body.Type: ApplicationFiled: September 11, 2020Publication date: December 31, 2020Applicant: Edwards Lifesciences CorporationInventors: Ilia Hariton, Netanel Benichou, Yaacov Nitzan, Bella Felsen, Diana Nguyen-Thien-Nhon, Rajesh A. Khanna, Son V. Nguyen, Tamir S. Levi, Itai Pelled
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Publication number: 20200402848Abstract: Low capacitance and high reliability interconnect structures and methods of manufacture are disclosed. The method includes forming a copper based interconnect structure in an opening of a dielectric material. The method further includes forming a capping layer on the copper based interconnect structure. The method further includes oxidizing the capping layer and any residual material formed on a surface of the dielectric material. The method further includes forming a barrier layer on the capping layer by outdiffusing a material from the copper based interconnect structure to a surface of the capping layer. The method further includes removing the residual material, while the barrier layer on the surface of the capping layer protects the capping layer.Type: ApplicationFiled: September 3, 2020Publication date: December 24, 2020Inventors: Daniel C. Edelstein, Son V. Nguyen, Takeshi Nogami, Deepika Priyadarshini, Hosadurga K. Shobha