Abstract: A method is proposed for sample processing. A first group of data are received, here data in the first group of data comprises a sample and a classification of the sample, and the classification belonging to a first group of classifications in a plurality of classifications associated with the data. A plurality of data with the classification are selected from the first group of data. A first and a second loss function are determined for training a classification model that represents an association relationship between samples and classifications of the samples based on a plurality of samples comprised in the plurality of data and the classification, the first and second loss functions represent classification accuracy and a feature distribution for the classification model. The classification model is trained based on the first and second loss functions. Therefore, the accuracy of the classification model may be increased.

Abstract: An identity certificate may be issued to a blockchain node. The issuance may include issuing a first identity certificate to a first terminal and receiving a second identity certificate issuance request that is from the first terminal. A second identity certificate may be issued to the first terminal, and a third identity certificate issuance request is received from the second terminal. A third identity certificate is issued to the second terminal, so that the second terminal forwards the third identity certificate to the third terminal.

Abstract: Provided are a display panel and a method for manufacturing the same, a display device and a control method of the same related to the technical field of display. The display panel includes a base substrate; a pixel defining layer arranged on the base substrate and configured to define a plurality of sub-pixels, at least one sub-pixel of the plurality of sub-pixels includes a plurality of sub-pixel-units; and each sub-pixel-unit of the plurality of sub-pixels includes an anode, a light emitting layer, and a cathode that are stacked, and anodes of adjacent sub-pixel-units in a same sub-pixel are insulated from each other and are apart from the base substrate for different distances.

Abstract: A container for culturing a blood sample. The container has a reservoir that is no larger than about 40 ml in volume with culture media therein varying in amount by volume 0.5 ml to about 20 ml. The container is adapted to receive a blood sample drawn from a patient, wherein the blood volume is about 1 ml to about 20 ml. In some embodiments the ratio of blood volume to culture media volume is about 2:1 to about 1:2 and the volume of blood does not exceed about 10 ml. In some embodiments, the media is lytic media. A method for using the container to culture a blood sample is also contemplated. In such method, the container is inoculated with the blood sample. In certain embodiments, the volume of the blood sample does not exceed 10 mls.

Abstract: Rapid methods that identify sepsis-causing bacteria or yeast aid the physician in critical therapeutic decision-making, thus decreasing patient mortality rates. The methods described herein employ plating microorganisms directly on to a MALDI-MS plate, adding concentrated formic acid, and identifying the microorganism by mass spectrometry. Optionally, an organic solvent may be combined with the formic acid, or added to the sample before or after the concentrated formic acid is added thereto. The methods enable direct extraction of proteins from microorganisms without the need for liquid protein extraction methods and yields positive identification results for gram-positive bacteria, gram-negative bacteria and yeast in minutes.

Abstract: A method for detecting the presence of a microorganism in a fluid sample is disclosed. The method includes providing a fluid specimen within a specimen collection container having a sidewall defining an interior therein. The interior includes a mechanical separator adapted for separating the fluid sample into first and second phases within the specimen collection container and a sensing element capable of detecting the presence of a microorganism disposed therein. The method includes subjecting the specimen collection container to applied rotational force to isolate a concentrated microorganism region. The method also includes detecting by a sensing element the presence or absence of a microorganism within the concentrated microorganism region.

Abstract: Rapid methods that identify sepsis-causing bacteria or yeast aid the physician in critical therapeutic decision-making, thus decreasing patient mortality rates. The methods described herein employ plating microorganisms directly on to a MALDI-MS plate, adding concentrated formic acid, and identifying the microorganism by mass spectrometry. Optionally, an organic solvent may be combined with the formic acid, or added to the sample before or after the concentrated formic acid is added thereto. The methods enable direct extraction of proteins from microorganisms without the need for liquid protein extraction methods and yields positive identification results for gram-positive bacteria, gram-negative bacteria and yeast in minutes.

Abstract: A method for unbalancing a tri-level switching regulator uses hysteretic control when switching across multiple states of the tri-level switching regulator. The method includes determining a battery voltage and an output voltage of the tri-level switching regulator. The method also includes dynamically adjusting at least one of a first hysteretic window of a first hysteretic comparator associated with a second switching state of the tri-level switching regulator and a second hysteretic window of a second hysteretic comparator associated with a first switching state of the tri-level switching regulator based on the battery voltage and the output voltage.

Abstract: An apparatus is disclosed for a single-inductor multiple-output (SIMO) power converter with a cross-regulation switch. An example apparatus includes a power source and a SIMO power converter. The SIMO power converter includes an input node coupled to the power source, a first node, a second node, a ground node, and an inductor coupled between the first node and the second node. The single-inductor multiple-output power converter also includes a first switch coupled between the input node and the first node, a second switch coupled between the first node and the ground node, and a cross-regulation switch coupled between the input node and the second node.

Abstract: A method for unbalancing a tri-level switching regulator uses hysteretic control when switching across multiple states of the tri-level switching regulator. The method includes determining a battery voltage and an output voltage of the tri-level switching regulator. The method also includes dynamically adjusting at least one of a first hysteretic window of a first hysteretic comparator associated with a second switching state of the tri-level switching regulator and a second hysteretic window of a second hysteretic comparator associated with a first switching state of the tri-level switching regulator based on the battery voltage and the output voltage.

Abstract: An apparatus is disclosed for a single-inductor multiple-output (SIMO) power converter with a cross-regulation switch. An example apparatus includes a power source and a SIMO power converter. The SIMO power converter includes an input node coupled to the power source, a first node, a second node, a ground node, and an inductor coupled between the first node and the second node. The single-inductor multiple-output power converter also includes a first switch coupled between the input node and the first node, a second switch coupled between the first node and the ground node, and a cross-regulation switch coupled between the input node and the second node.

Abstract: A tri-level converter provides three levels of power supply to a power amplifier that includes a supply path. The supply path has a first transistor and a first inherent body diode associated with the first transistor, as well as a second transistor and a second inherent body diode associated with the second transistor. A polarity of the second body diode is reversed relative to a polarity of the first body diode. A first driver is configured to drive the first transistor and the first inherent body diode to control a power supply, including a battery supply signal, to an output of the tri-level converter. The tri-level converter is coupled to a switching node.

Abstract: Rapid methods that identify sepsis-causing bacteria or yeast aid the physician in critical therapeutic decision-making, thus decreasing patient mortality rates. The methods described herein employ plating microorganisms directly on to a MALDI-MS plate, adding concentrated formic acid, and identifying the microorganism by mass spectrometry. Optionally, an organic solvent may be combined with the formic acid, or added to the sample before or after the concentrated formic acid is added thereto. The methods enable direct extraction of proteins from microorganisms without the need for liquid protein extraction methods and yields positive identification results for gram-positive bacteria, gram-negative bacteria and yeast in minutes.

Abstract: Certain aspects of the present disclosure provide methods and apparatus for generating an envelope tracking power supply voltage. For example, certain aspects of the present disclosure provide an envelope tracking power supply having a linear amplifier having an output coupled to a power supply node of an amplifier, wherein a power supply node of the linear amplifier is coupled to a first voltage supply node. The envelope tracking power supply may also include a switch mode power supply having an output coupled to the power supply node of the amplifier. Certain aspects also include a circuit having a first switch coupled to the first voltage supply node and a second switch coupled to a second voltage supply node, wherein a power supply node of the switch mode power supply is coupled to the first switch and the second switch.

Abstract: Rapid methods that identify sepsis-causing bacteria or yeast aid the physician in critical therapeutic decision-making, thus decreasing patient mortality rates. The methods described herein employ plating microorganisms directly on to a MALDI-MS plate, adding concentrated formic acid, and identifying the microorganism by mass spectrometry. Optionally, an organic solvent may be combined with the formic acid, or added to the sample before or after the concentrated formic acid is added thereto. The methods enable direct extraction of proteins from microorganisms without the need for liquid protein extraction methods and yields positive identification results for gram-positive bacteria, gram-negative bacteria and yeast in minutes.

Abstract: Certain aspects of the present disclosure provide methods and apparatus for generating an envelope tracking power supply voltage. For example, certain aspects of the present disclosure provide an envelope tracking power supply having a linear amplifier having an output coupled to a power supply node of an amplifier, wherein a power supply node of the linear amplifier is coupled to a first voltage supply node. The envelope tracking power supply may also include a switch mode power supply having an output coupled to the power supply node of the amplifier. Certain aspects also include a circuit having a first switch coupled to the first voltage supply node and a second switch coupled to a second voltage supply node, wherein a power supply node of the switch mode power supply is coupled to the first switch and the second switch.

Abstract: Certain aspects of the present disclosure provide methods and apparatus for generating an envelope tracking power supply voltage. For example, certain aspects of the present disclosure provide an envelope tracking power supply having a linear amplifier having an output coupled to a power supply node of an amplifier, wherein a power supply node of the linear amplifier is coupled to a first voltage supply node. The envelope tracking power supply may also include a switch mode power supply having an output coupled to the power supply node of the amplifier. Certain aspects also include a circuit having a first switch coupled to the first voltage supply node and a second switch coupled to a second voltage supply node, wherein a power supply node of the switch mode power supply is coupled to the first switch and the second switch.

Abstract: A container for culturing a blood sample. The container has a reservoir that is no larger than about 40 ml in volume with culture media therein varying in amount by volume 0.5 ml to about 20 ml. The container is adapted to receive a blood sample drawn from a patient, wherein the blood volume is about 1 ml to about 20 ml. In some embodiments the ratio of blood volume to culture media volume is about 2:1 to about 1:2 and the volume of blood does not exceed about 10 ml. In some embodiments, the media is lytic media. A method for using the container to culture a blood sample is also contemplated. In such method, the container is inoculated with the blood sample. In certain embodiments, the volume of the blood sample does not exceed 10 mls.

Abstract: The present invention relates to methods, monitors and systems, useful, for example, for advanced detection of sepsis in a subject.

Abstract: Certain aspects of the present disclosure provide methods and apparatus for operating an envelope tracking power supply. The method may include receiving, from a modem of a device, information indicative of a transmit waveform statistic of a signal to be wirelessly transmitted by the device. The method may further include adjusting a configuration of the envelope tracking power supply based on the transmit waveform statistic of the signal.