Abstract: Certain aspects of the present disclosure provide methods and apparatus for operating an envelope tracking power supply. The method may include receiving, from a modem of a device, information indicative of a transmit waveform statistic of a signal to be wirelessly transmitted by the device. The method may further include adjusting a configuration of the envelope tracking power supply based on the transmit waveform statistic of the signal.

Abstract: The present invention relates to methods, monitors and systems, useful, for example, for advanced detection of sepsis in a subject.

Abstract: A method for preparing 2-mercaptobenzothiazole where the aniline method is adopted to perform reaction in the presence of a catalyst, and the catalyst includes sulfonic acid type imidazolium ionic liquid. The sulfonic acid type imidazolium ionic liquid is a type of acidic functionalized ionic liquid, and has the advantages of both a solid acid and a liquid acid. The sulfonic acid type imidazolium ionic liquid is adopted as an active ingredient of the catalyst, and may remarkably improve a conversion rate of the reaction raw materials and increase a yield of the 2-mercaptobenzothiazole. Meanwhile, due to the characteristics of high catalytic activity, no volatilization, low corrosion, high thermal stability and the like of the 2-mercaptobenzothiazole, the preparation method also has the comprehensive advantages of simple process, low cost, low tar yield, high environment friendliness and the like.

Abstract: A method for preparing 2-mercaptobenzothiazole where the aniline method is adopted to perform reaction in the presence of a catalyst, and the catalyst includes sulfonic acid type imidazolium ionic liquid. The sulfonic acid type imidazolium ionic liquid is a type of acidic functionalized ionic liquid, and has the advantages of both a solid acid and a liquid acid. The sulfonic acid type imidazolium ionic liquid is adopted as an active ingredient of the catalyst, and may remarkably improve a conversion rate of the reaction raw materials and increase a yield of the 2-mercaptobenzothiazole. Meanwhile, due to the characteristics of high catalytic activity, no volatilization, low corrosion, high thermal stability and the like of the 2-mercaptobenzothiazole, the preparation method also has the comprehensive advantages of simple process, low cost, low tar yield, high environment friendliness and the like.

Abstract: An array of micro-chambers (220) with ISFETs (300) disposed therein for monitoring single cell activity in the microarray to determine the presence or absence of microorganisms in a sample (390).

Abstract: Described herein are methods and reagents for identifying and analyzing at least one microorganism (e.g. bacteria) in a sample and reducing the background signal intensity obtained when analyzing the sample by flow cytometry. The sample is prepared by combining the sample with a background signal-reducing molecule or with a nucleic acid stain covalently linked to a quencher. A portion of the particulate matter in the sample can optionally be removed with a resin prior to staining with a nucleic acid stain.

Abstract: The present disclosure describes a synchronized switching power supply for a radio frequency (RF) power amplifier. In some aspects, a synchronized power supply circuit comprises a first switch connected between a power rail and a first terminal of an inductor that is connected to an output of the circuit via its second terminal. The circuit also includes a second switch connected between a ground rail and the first terminal of the inductor, and respective gate drivers for the first and second switches. An amplifier of the circuit is connected to the power rail and has an output connected to the output of the circuit. A current sensor is connected between the output of the amplifier and the output of the circuit, with an output of the current sensor being connected to an input of a comparator. A delay circuit is connected between an output of the comparator and the first and second gate drivers, and may synchronize the power supply circuit.

Abstract: The present disclosure describes a synchronized switching power supply for a radio frequency (RF) power amplifier. In some aspects, a synchronized power supply circuit comprises a first switch connected between a power rail and a first terminal of an inductor that is connected to an output of the circuit via its second terminal. The circuit also includes a second switch connected between a ground rail and the first terminal of the inductor, and respective gate drivers for the first and second switches. An amplifier of the circuit is connected to the power rail and has an output connected to the output of the circuit. A current sensor is connected between the output of the amplifier and the output of the circuit, with an output of the current sensor being connected to an input of a comparator. A delay circuit is connected between an output of the comparator and the first and second gate drivers, and may synchronize the power supply circuit.

Abstract: The present invention relates to methods, monitors and systems, useful, for example, for advanced detection of sepsis in a subject.

Abstract: Certain aspects of the present disclosure provide methods and apparatus for generating an envelope tracking power supply voltage. For example, certain aspects of the present disclosure provide an envelope tracking power supply having a linear amplifier having an output coupled to a power supply node of an amplifier, wherein a power supply node of the linear amplifier is coupled to a first voltage supply node. The envelope tracking power supply may also include a switch mode power supply having an output coupled to the power supply node of the amplifier. Certain aspects also include a circuit having a first switch coupled to the first voltage supply node and a second switch coupled to a second voltage supply node, wherein a power supply node of the switch mode power supply is coupled to the first switch and the second switch.

Abstract: Certain aspects of the present disclosure provide methods and apparatus for adjusting voltage regulators of a power supply, such as an envelope tracking power supply. Certain aspects provide a power supply. The power supply may include a first voltage regulator having an output coupled to a voltage supply node of an amplifier. The power supply may further include a second voltage regulator having an output coupled to the voltage supply node of the amplifier. The power supply may further include a controller for adjusting a ratio of an average current supplied by the first voltage regulator to an average current supplied by the second voltage regulator to the voltage supply node of the amplifier based on an output voltage supplied to the voltage supply node of the amplifier by the first voltage regulator and the second voltage regulator.

Abstract: Certain aspects of the present disclosure provide methods and apparatus for operating an envelope tracking power supply. The method may include receiving, from a modem of a device, information indicative of a transmit waveform statistic of a signal to be wirelessly transmitted by the device. The method may further include adjusting a configuration of the envelope tracking power supply based on the transmit waveform statistic of the signal.

Abstract: The present invention relates to methods, monitors and systems, useful, for example, for advanced detection of sepsis in a subject.

Abstract: An array of micro-chambers (220) with ISFETs (300) disposed therein for monitoring single cell activity in the microarray to determine the presence or absence of microorganisms in a sample (390).

Abstract: Rapid methods that identify sepsis-causing bacteria or yeast aid the physician in critical therapeutic decision-making, thus decreasing patient mortality rates. The methods described herein employ plating microorganisms directly on to a MALDI-MS plate, adding concentrated formic acid, and identifying the microorganism by mass spectrometry. Optionally, an organic solvent may be combined with the formic acid, or added to the sample before or after the concentrated formic acid is added thereto. The methods enable direct extraction of proteins from microorganisms without the need for liquid protein extraction methods and yields positive identification results for gram-positive bacteria, gram-negative bacteria and yeast in minutes.

Abstract: The present invention relates to methods, monitors and systems, useful, for example, for advanced detection of sepsis in a subject.

Abstract: An array of micro-chambers (220) with individual ion sensitive field effect transistors (ISFETs) (300) disposed therein for monitoring single cell activity in the microarray to determine the presence or absence of microorganisms in a sample (390). In addition to the presence or absence of a single cell, certain further embodiments contemplate monitoring cell behavior. Cell behavior includes the entire range of cell activity as well as cell response to changes in environmental conditions of changes in response due to the addition of sample constituents.

Abstract: A process for determining one of the presence, absence, or total of microorganisms (e.g. bacteria) in a sample. According to the process, a biological sample containing complex matrices is obtained. The sample is first combined with a resin to adsorb complex matrices from the sample. The resin is removed from the biological sample. The sample so prepared is then analyzed by flow cytometry.

Abstract: Rapid methods that identify sepsis-causing bacteria or yeast aid the physician in critical therapeutic decision-making, thus decreasing patient mortality rates. The methods described herein employ plating microorganisms directly on to a MALDI-MS plate, adding concentrated formic acid, and identifying the microorganism by mass spectrometry. Optionally, an organic solvent may be combined with the formic acid, or added to the sample before or after the concentrated formic acid is added thereto. The methods enable direct extraction of proteins from microorganisms without the need for liquid protein extraction methods and yields positive identification results for gram-positive bacteria, gram-negative bacteria and yeast in minutes.

Abstract: The present disclosure includes envelope tracking circuits and methods with adaptive switching frequency. In one embodiment, a circuit comprising an amplifier to receive an envelope tracking signal having an envelope tracking frequency and output voltage and current to a power supply terminal of a power amplifier circuit. A programmable comparator receives an output signal from the amplifier and generates a switching signal having a switching frequency. A switching regulator stage receives the switching signal and outputs a switching current to the power supply terminal. A frequency comparison circuit configures the programmable comparator based on the envelope tracking frequency and the switching frequency so that the switching frequency tracks the envelope tracking frequency.