Abstract: The present disclosure is directed towards systems and methods for flexible field mapping between disparate systems, which comprises generating a base mapping request comprising a base mapping between a source data object having one or more source data fields and a target data object having one or more target data fields and generating a field mapping request comprising a field mapping between a given source data field and a given target data field. One or more data items are identified from the target data object responsive to the base mapping request and the field mapping request. A combined request is then generated comprising the one or more data items responsive to the base mapping request and the field mapping request. The combined request is transmitted to a target memory. One or more tax values responsive to the combined request are subsequently calculated based on the one or more data items.

Abstract: A method is provided for operating a heat accumulator of a motor vehicle. Accordingly, following a start of the motor vehicle, a length and/or duration of a distance to be driven by the motor vehicle are/is ascertained or estimated. Depending on the length and/or the duration, a decision is made as to whether discharging of the heat accumulator will be carried out.

Abstract: The present invention provides a compound of formula I: a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

Abstract: The present invention provides a compound of formula (I) a method for manufacturing the compounds of the invention, and its therapeutic uses as complement pathway modulators for the treatment of ocular diseases. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

Abstract: The present invention provides a compound of formula I: (I) a method for manufacturing the compounds of the invention, and its therapeutic uses as complement alternative inhibitors for the treatment of ocular diseases. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

Abstract: The present invention provides a compound of formula (I) a method for manufacturing the compounds of the invention and its therapeutic uses as complement pathway modulators for the treatment of ocular diseases. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

Abstract: The present invention provides a compound of formula (I): a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

Abstract: The present invention provides a compound of formula I: a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

Abstract: The present invention provides a compound of formula I: (I) a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

Abstract: The present invention provides a compound of formula I a method for manufacturing the compounds of the invention, and its therapeutic uses as inhibitor of the complement alternative pathway and particularly as inhibitor of Factor B for the treatment of e.g. age-related macular degeneration and diabetic retinopathy. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

Abstract: A method for controlling an internal combustion engine and an E-machine of a hybrid electrical vehicle. In this case, the control of the internal combustion engine takes place as a function of a current and an expected waste heat of an electrical drive of the hybrid electrical vehicle.

Abstract: A method for electrically regenerating an electrical energy store in a motor vehicle which includes a recuperation device and/or other energy-saving devices, including the following: based on information concerning an upcoming travel route, it is ascertained whether a suitable opportunity exists for an electrical regeneration on the upcoming travel route, and when this is the case: a first energy loss is determined which occurs during the electrical regeneration; a second energy loss is determined which results on a plurality of previously determined and defined routes due to aging effects of the energy store which are reversible with the aid of regeneration; the first energy loss and the second energy loss are compared, and a regeneration is carried out only when the second energy loss is greater than the first energy loss.

Abstract: Techniques are disclosed for facilitating the process of undoing and redoing modifications that are made to content using an online content management system (CMS). As a user makes changes to content, such as by editing a webpage using a web-based CMS, a history of the user's modifications is generated and stored locally on the client. When the user invokes an undo command, the modification history can be used to determine a previous state of the content and restore the content to that previous state. Similarly, when the user invokes a redo command, the modification history can be used to return to a state that had previously been undone. In some embodiments, the process of undoing or redoing the user's modifications is selectively performed on either a client side or a server side of the online system, depending on the type of content that is being manipulated.

Abstract: A system for determining accessibility of a tool to an object is provided. The system provides for selecting one or more sections on the object to be laser shock peened, selecting a region of interest on the one or more sections and determining a set of feasible solutions to access the selected region of interest on each of the one or more sections via use of an accessibility system.

Abstract: The invention relates to a part for a component for high-pressure liquid chromatography (HPLC), in particular a pump head for an HPLC pump, in which the strength has been increased by autofrettage and which consists of a material which is essentially chemically inert to the fluids used in HPLC. The invention further relates to an HPLC pump having a pump head which is configured as such a part.

Abstract: A system for determining accessibility of a tool to an object is provided. The system provides for selecting one or more sections on the object to be laser shock peened, selecting a region of interest on the one or more sections and determining a set of feasible solutions to access the selected region of interest on each of the one or more sections via use of an accessibility system.

Abstract: A method for determining accessibility of a tool to an object is provided. The method provides for selecting one or more sections on the object to be laser shock peened, selecting a region of interest on the one or more sections and determining a set of feasible solutions to access the selected region of interest on each of the one or more sections via use of an accessibility system. Systems and computer programs that afford functionality of the type defined by this method may be provided by the present technique.

Abstract: The present invention provides a compound of formula I: a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

Abstract: The present invention relates to the crystal structure of the serine protease kallikrein 7 and to the use of this crystal structure in drug discovery. The present invention also relates to compounds binding specifically to this active site of kallikrein 7.