Abstract: The invention provides (a) an HIV Tat protein or derivative thereof linked to either (i) a fusion partner or (ii) an HIV Nef protein or derivative thereof; or (b) an HIV Nef protein or derivative thereof linked to either (i) a fusion partner or (ii) an HIV Tat protein or derivative thereof; or (c) an HIV Nef protein or derivative thereof linked to an HIV Tat protein or derivative thereof and a fusion partner. The invention further provides for a nucleic acid encoding such a protein and a host cell, such as Pichia Pastoris, transformed with the aforementioned nucleic acid.

Abstract: The invention provides (a) an HIV Tat protein or derivative thereof linked to either (i) a fusion partner or (ii) an HIV Nef protein or derivative thereof; or (b) an HIV Nef protein or derivative thereof linked to either (i) a fusion partner or (ii) an HIV Tat protein or derivative thereof; or (c) an HIV Nef protein or derivative thereof linked to an HIV Tat protein or derivative thereof and a fusion partner. The invention further provides for a nucleic acid encoding such a protein and a host cell, such as Pichia Pastoris, transformed with the aforementioned nucleic acid.

Abstract: The invention concerns a method for transmitting in an area (100) information items in the form of sound waves representing a signal X(t), through a loudspeaker enclosure (2), said method comprising a step of setting up a public address system which consists in applying to the input of the loudspeaker enclosure (2) an electric signal P(t)=W(t) ?X(t) wherein is the convolution product and W(t)=S(?t)? I(t), wherein S(?t) is the temporal return of the pulse response S(t) between the enclosure and the target zone (101) belonging to the area to be fitted with a P.A. system (100) t representing time, and I(t) is the temporal response of the product e?2inft0.Sc (f), wherein f represents the frequency, t0 is a constant Sc(f)=1/(S1(f))?, ? being a non-null positive number and S1(f) being a real function obtained by peak clipping of the modulo I S(f) I of the frequency response S(f) of S(t).

Abstract: The present invention relates to a guide device suitable for use in an offshore drilling installation, in which installation at least one drilling riser extends from a floating support to said guide devices on the seabed, said guide device being characterized in that it comprises a guide pipe in a buried position wherein said guide pipe comprises in succession: a front end resting horizontally on the seabed; a curved intermediate portion of guide pipe buried in the subsoil of the seabed at a radius of curvature that is larger, the radius of curvature preferably being greater than 500 m, and more preferably lying in the range 500 m to 1000 m; and an inclined substantially linear rear portion at the rear end of said guide pipe buried in the subsoil of the seabed at a given angle of inclination lying in the range 5° to 60°; said guide pipe co-operating with controlled burying means.