Patents by Inventor Stephan MICHAEL
Stephan MICHAEL has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10639070Abstract: Disclosed is an implant needle for introducing an implant into a patient. The needle has a hollow main body having a receiving portion configured to receive an implant. A taper-shaped tip portion is cut from the hollow needle main body and includes a first slant surface contiguous to an outer peripheral surface of the main body and formed at a first predetermined angle with respect to an axis of the main body. The first slant surface has an inner non-cutting edge and an outer non-cutting edge. The needle also includes a pair of second slant surfaces, each of which forms a second predetermined angle with respect to the main body axis that is larger than the first predetermined angle. Each second slant surface has an inner non-cutting edge and an outer cutting edge that is contiguous with an edge point of the tip portion. A method of manufacturing the implant needle is also disclosed.Type: GrantFiled: August 24, 2016Date of Patent: May 5, 2020Assignee: Roche Diabetes Care, Inc.Inventors: Stephan-Michael Frey, Oliver Kube, Andrea Rittinghaus
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Publication number: 20200130864Abstract: A method and system provide the ability to autonomously operate an unmanned aerial system (UAS) over long durations of time. The UAS vehicle autonomously takes off from a take-off landing-charging station and autonomously executes a mission. The mission includes data acquisition instructions in a defined observation area. Upon mission completion, the UAS autonomously travels to a target landing-charging station and performs an autonomous precision landing on the target landing-charging station. The UAS autonomously re-charges via the target landing-charging station. Once re-charged, the UAS is ready to execute a next sortie. When landed, the UAS autonomously transmits mission data to the landing-charging station for in situ or cloud-based data processing.Type: ApplicationFiled: October 29, 2019Publication date: April 30, 2020Applicant: California Institute of TechnologyInventors: Roland Brockers, Stephan Michael Weiss, Danylo Malyuta, Christian Brommer, Daniel Robert Hentzen
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Patent number: 10589059Abstract: An insertion device (110) for inserting an analyte sensor (114) into a body tissue is proposed. The insertion device (110) comprises an insertion needle holder (120) and a drive mechanism (124) for linearly driving the insertion needle holder (120) in a longitudinal direction (126). The drive mechanism (124) comprises at least one actuator (132) for actuating the drive mechanism (124). The actuator (132) comprises at least one actuator arm (136, 138) which is pivotable about at least one axle (140) in order to actuate the drive mechanism (124). The insertion device (110) further comprises at least one protection against reuse including at least one locking mechanism (178). The locking mechanism (178) is adapted to at least partially prevent a back-pivoting of the actuator arm (136, 138) in a direction reversing the actuation direction once the actuator arm (136, 138) has been pivoted by at least one threshold angle.Type: GrantFiled: July 22, 2015Date of Patent: March 17, 2020Assignee: ROCHE DIABETES CARE, INC.Inventors: Stephan-Michael Frey, Oliver Kube, Andrea Rittinghaus
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Publication number: 20200008838Abstract: The present disclosure refers to an implant needle (1) for introducing an implant into a body of a patient, comprising a receiving portion configured to receive an implant and provided in a hollow needle main body (2), and a taper-shaped tip portion (3). The taper-shaped tip portion (3) is further comprising: a first slant surface (14a) contiguous to a first outer peripheral surface (15) of the hollow needle main body (2), wherein the first slant surface (14a) is provided as a first non-cutting edge; a second slant surface (16a) contiguous to a second outer peripheral surface (17) of the hollow needle main body (2), wherein the second slant surface (16a) is provided as a second non-cutting edge; and a pair of sharpened surfaces (9a, 9b) symmetric with respect to an edge point (10) and a longitudinal axis (13) of the needle main body (2), wherein the sharpened surfaces (9a, 9b) are both provided with a cutting edge.Type: ApplicationFiled: March 12, 2018Publication date: January 9, 2020Applicant: Roche Diabetes Care, Inc.Inventors: Stephan-Michael Frey, Oliver Kube
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Publication number: 20190374138Abstract: A kit (110) for determining a concentration of at least one analyte in a body fluid of a user is disclosed, the kit (110) comprising: a) a sensor module (112) comprising i. at least one sensor element (114) adapted to determine the concentration of the analyte, wherein the sensor element (114) is at least partly implantable into a body tissue (174) of the user; ii.Type: ApplicationFiled: September 1, 2016Publication date: December 12, 2019Inventors: Stephan-Michael Frey, Oliver Kube, Wolfgang Heck, Helmut Walter
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Publication number: 20190353662Abstract: Various aspects and embodiments of the present disclosure are directed to methods and compositions (e.g., kits) for the identification of subjects with misfolded proteins in their urine. For example, methods and compositions for determining that a urine sample from a pregnant woman contains or does not contain misfolded are provided. In some embodiments, the presence of misfolded proteins in a urine sample from a pregnant woman is an indication of preeclampsia.Type: ApplicationFiled: May 8, 2019Publication date: November 21, 2019Applicant: Yale UniversityInventors: Irina Buhimschi, Catalin S. Buhimschi, Michael Choma, Hemant Tagare, Stephan Michael Jonas
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Publication number: 20190231238Abstract: A medical device (110) for detecting at least one analyte in a body fluid, a method of using a medical device (110) and a method for assembling a medical device are disclosed.Type: ApplicationFiled: August 3, 2017Publication date: August 1, 2019Applicant: Roche Diabetes Care, Inc.Inventors: Stephan-Michael FREY, Oliver KUBE, Helmut WALTER, Klaus CORNELIUS
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Patent number: 10324094Abstract: Various aspects and embodiments of the present disclosure are directed to methods and compositions (e.g., kits) for the identification of subjects with misfolded proteins in their urine. For example, methods and compositions for determining that a urine sample from a pregnant woman contains or does not contain misfolded are provided. In some embodiments, the presence of misfolded proteins in a urine sample from a pregnant woman is an indication of preeclampsia.Type: GrantFiled: April 10, 2015Date of Patent: June 18, 2019Assignee: Yale UniversityInventors: Irina Buhimschi, Catalin S. Buhimschi, Michael Choma, Hemant Tagare, Stephan Michael Jonas
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Patent number: 10092239Abstract: A biosensor is proposed for insertion into the subcutaneous tissue of a user wherein the biosensor includes at least one flexible substrate and at least one electrode on at least one surface of the substrate and at least one contacting element. The contacting element is connected to the electrode. The substrate has at least one kink, at which the substrate is at least partly kinked such that the surface is subdivided into at least two interconnected outer surfaces.Type: GrantFiled: July 31, 2017Date of Patent: October 9, 2018Assignee: Roche Diabetes Care, Inc.Inventors: Stephan-Michael Frey, Oliver Kube
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Patent number: 9999381Abstract: A device for performing at least one medical function on a user is proposed. The device has at least one medical functional element that is designed to perform the medical function. The medical function is selected from a diagnostic, a therapeutic and a surgical function. The device has at least one evaluation and control part that comprises at least one actuation component for controlling the medical function. The evaluation and control part has at least one casing and at least one battery receptacle. The battery receptacle comprises at least one electrical energy reservoir, more particularly at least one battery. The battery receptacle is designed to be opened irreversibly by the user for removing the energy reservoir.Type: GrantFiled: April 17, 2017Date of Patent: June 19, 2018Assignee: ROCHE DIABETES CARE, INC.Inventors: Stephan-Michael Frey, Helmut Walter, Jürgen Braun, Jürgen Pfrang
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Patent number: 9883888Abstract: A sensor cartridge comprising a sterile capsule. The sensor cartridge further comprises a sensor within the sterile capsule. The sensor cartridge further comprises a sensor connector connected to the sensor in an initial position. The sensor cartridge further comprises an insertion needle for inserting the sensor into a subject. The insertion needle is within the sterile capsule. The sensor cartridge further comprises a sensor mounting unit for receiving the sensor connector at a mounted position. The sensor mounting unit comprises an adhesive surface for attaching to an exterior surface of the subject. The sensor cartridge further comprises an insertion mechanism operable for actuating the insertion needle and moving the sensor connector from the initial position to the mounted position.Type: GrantFiled: November 26, 2014Date of Patent: February 6, 2018Assignee: Roche Diabetes Care, Inc.Inventors: Stephan-Michael Frey, Wolfgang Heck, Oliver Kube, Helmut Walter
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Patent number: 9844343Abstract: A biosensor is proposed for insertion into the subcutaneous tissue of a user wherein the biosensor includes at least one flexible substrate (2) and at least one electrode (5) on at least one surface (9) of the substrate and at least one contacting element (3). The contacting element is connected to the electrode. The substrate has at least one kink (4), at which the substrate is at least partly kinked such that the surface is subdivided into at least two interconnected outer surfaces (9a, 9b, 9c).Type: GrantFiled: June 28, 2013Date of Patent: December 19, 2017Assignee: Roche Diabetes Care, Inc.Inventors: Stephan-Michael Frey, Oliver Kube
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Publication number: 20170325745Abstract: A biosensor is proposed for insertion into the subcutaneous tissue of a user wherein the biosensor includes at least one flexible substrate and at least one electrode on at least one surface of the substrate and at least one contacting element. The contacting element is connected to the electrode. The substrate has at least one kink, at which the substrate is at least partly kinked such that the surface is subdivided into at least two interconnected outer surfaces.Type: ApplicationFiled: July 31, 2017Publication date: November 16, 2017Inventors: Stephan-Michael Frey, Oliver Kube
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Publication number: 20170311892Abstract: A biosensor is proposed for insertion into the subcutaneous tissue of a user wherein the biosensor includes at least one flexible substrate (2) and at least one electrode (5) on at least one surface (9) of the substrate and at least one contacting element (3). The contacting element is connected to the electrode. The substrate has at least one kink (4), at which the substrate is at least partly kinked such that the surface is subdivided into at least two interconnected outer surfaces (9a, 9b, 9c).Type: ApplicationFiled: June 28, 2013Publication date: November 2, 2017Applicant: ROCHE DIAGNOSTICS OPERATIONS, INC.Inventors: Stephan-Michael Frey, Oliver Kube
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Publication number: 20170215776Abstract: A device for performing at least one medical function on a user is proposed. The device has at least one medical functional element that is designed to perform the medical function. The medical function is selected from a diagnostic, a therapeutic and a surgical function. The device has at least one evaluation and control part that comprises at least one actuation component for controlling the medical function. The evaluation and control part has at least one casing and at least one battery receptacle. The battery receptacle comprises at least one electrical energy reservoir, more particularly at least one battery. The battery receptacle is designed to be opened irreversibly by the user for removing the energy reservoir.Type: ApplicationFiled: April 17, 2017Publication date: August 3, 2017Applicant: Roche Diabetes Care, Inc.Inventors: Stephan-Michael Frey, Helmut Walter, Jürgen Braun, Jürgen Pfrang
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Publication number: 20170165451Abstract: An insertion device (110) for inserting an analyte sensor (114) into a body tissue is proposed. The insertion device (110) comprises an insertion needle holder (120) and a drive mechanism (124) for linearly driving the insertion needle holder (120) in a longitudinal direction (126). The drive mechanism (124) comprises at least one actuator (132) for actuating the drive mechanism (124). The actuator (132) comprises at least one actuator arm (136, 138) which is pivotable about at least one axle (140) in order to actuate the drive mechanism (124). The insertion device (110) further comprises at least one protection against reuse including at least one locking mechanism (178). The locking mechanism (178) is adapted to at least partially prevent a back-pivoting of the actuator arm (136, 138) in a direction reversing the actuation direction once the actuator arm (136, 138) has been pivoted by at least one threshold angle.Type: ApplicationFiled: July 22, 2015Publication date: June 15, 2017Inventors: Stephan-Michael Frey, Oliver Kube, Andrea Rittinghaus
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Publication number: 20170165452Abstract: The invention relates to an insertion device (110) for inserting an analyte sensor (114) into a body tissue. The insertion device (110) comprises an insertion needle holder (120) and a drive mechanism (124) for driving the insertion needle holder (120) in a longitudinal direction (126). The drive mechanism (124) comprises at least one actuator (132) for actuating the drive mechanism (124). The drive mechanism (124) comprises a rotor (142) adapted to transform an actuation motion of the actuator (132) into a motion of the insertion needle holder (120) in the longitudinal direction (126). The insertion device (110) further comprises at least one safety lock (164). The safety lock (164), in a locked position, is adapted to at least partially block a rotation of the rotor (142). In an unlocked position, the safety lock (164) is adapted to permit the rotation of the rotor (142).Type: ApplicationFiled: July 22, 2015Publication date: June 15, 2017Inventors: Stephan-Michael Frey, Oliver Kube, Andrea Rittinghaus
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Patent number: 9655551Abstract: A device for performing at least one medical function on a user is proposed. The device has at least one medical functional element that is designed to perform the medical function. The medical function is selected from a diagnostic, a therapeutic and a surgical function. The device has at least one evaluation and control part that comprises at least one actuation component for controlling the medical function. The evaluation and control part has at least one casing and at least one battery receptacle. The battery receptacle comprises at least one electrical energy reservoir, more particularly at least one battery. The battery receptacle is designed to be opened irreversibly by the user for removing the energy reservoir.Type: GrantFiled: February 5, 2015Date of Patent: May 23, 2017Assignee: Roche Diabetes Care, Inc.Inventors: Stephan-Michael Frey, Helmut Walter, Jürgen Braun, Jürgen Pfrang
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Publication number: 20170128011Abstract: This disclosure concerns a medical sensor assembly comprising a flexible plaster adapted for adhesion on the skin of a patient and a sensor configured for transdermal measuring a physiological parameter, wherein the sensor has a measuring part insertable into the skin and a contact part for providing a signal connection to a measuring unit. It is proposed that the plaster has a flap which is adhered to an intermediate section of the sensor between the measuring part and the contact part.Type: ApplicationFiled: January 23, 2017Publication date: May 11, 2017Inventors: Stephan-Michael Frey, Oliver Kube, Helmut Walter
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Patent number: 9597035Abstract: The invention concerns a skin-mountable medical device comprising a patch portion with a contact surface facing the skin of a patient during use, a process unit attached to the patch portion, and a plaster kit for securing the patch portion to the skin, wherein the plaster kit has a primary pad adapted to releasably adhere to at least a section of a peripheral skin surface surrounding the contact surface. According to the invention, the plaster kit further comprises at least one auxiliary pad which is connectable or connected to the patch portion and adapted to functionally replace the primary pad after a wearing time.Type: GrantFiled: November 11, 2015Date of Patent: March 21, 2017Assignee: Roche Diabetes Care, Inc.Inventors: Stephan-Michael Frey, Oliver Kube, Helmut Walter