Patents by Inventor Stephen Barry

Stephen Barry has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7135600
    Abstract: The present invention relates to novel compounds of Formula (I), to a process for their manufacture, to pharmaceutical compositions containing them, and to their use in therapy, in particular their use in the prophylaxis and treatment of respiratory diseases.
    Type: Grant
    Filed: February 11, 2002
    Date of Patent: November 14, 2006
    Assignee: Glaxo Group Limited
    Inventors: Keith Biggadike, Diane Mary Coe, Stephen Barry Guntrip, Brian Edgar Looker, Panayiotis Alexandrou Procopiou
  • Patent number: 7109333
    Abstract: A process for the preparation of a compound of formula (I) comprising the steps: (a) reacting a compound of formula (II) ?wherein L and L? are suitable leaving groups, with a compound of formula (III) UNH2??(III) to prepare a compound of formula (IV) and subsequently (b) substituting the group R1 by replacement of the leaving group L?.
    Type: Grant
    Filed: February 3, 2005
    Date of Patent: September 19, 2006
    Assignee: SmithKline Beecham Corporation
    Inventors: Malcolm Clive Carter, George Stuart Cockerill, Stephen Barry Guntrip, Karen Elizabeth Lackey, Kathryn Jane Smith
  • Patent number: 7045658
    Abstract: The present invention relates to novel compounds of formula (I), to a process for their menufacture, to pharmaceutical compositions containing them, and to their use in therapy, in particular their use in the prophylaxis and treatment of respiratory diseases
    Type: Grant
    Filed: March 20, 2002
    Date of Patent: May 16, 2006
    Assignee: Glaxo Group Limited
    Inventors: Keith Biggadike, Rita Field, Stephen Barry Guntrip, Brian Edgar Looker
  • Publication number: 20050129769
    Abstract: Hydrophilic polymeric nanoarticles comprising a polymeric scaffold and one or more therapeutic agents, such as drug or drug-conjugate molecules, covalently attached to the scaffold. The articles may further optionally comprise recognition elements (REs) that bind to biomolecular structures expressed on certain cells or in certain tissues, to facilitate targeting and/or delivery.
    Type: Application
    Filed: November 22, 2004
    Publication date: June 16, 2005
    Inventors: Stephen Barry, Andrew Goodwin, Rachel Decor
  • Patent number: 6828320
    Abstract: Substituted heteroaromatic compounds, and in particular substituted quinolines and quinazolines, are protein tyrosine kinase inhibitors. The compounds are described as are methods for their preparation, pharmaceutical compositions including such compounds and their use in medicine, for example in the treatment of cancer and psoriasis.
    Type: Grant
    Filed: January 31, 2002
    Date of Patent: December 7, 2004
    Assignee: SmithKline Beecham Corporation
    Inventors: George Stuart Cockerill, Malcolm Clive Carter, Stephen Barry Guntrip, Kathryn Jane Smith
  • Publication number: 20040180876
    Abstract: The present invention relates to novel compounds of Formula (I), to a process for their manufacture, to pharmaceutical compositions containing them, and to their use in therapy, in particular their use in the prophylaxis and treatment of respiratory diseases.
    Type: Application
    Filed: February 9, 2004
    Publication date: September 16, 2004
    Inventors: Keith Biggadike, Diane Mary Coe, Dean David Edney, Stephen Barry Guntrip, Abigail Halton, Brian Edgar Looker, Michael John Monteith, Rajnikant Patel, Panayiotis Alexandrou Procopiou
  • Patent number: 6790324
    Abstract: An apparatus for producing orthohydrogen and/or parahydrogen. The apparatus includes a container holding water and at least one pair of closely-spaced electrodes arranged within the container and submerged in the water. A first power supply provides a particular first pulsed signal to the electrodes. A coil may also be arranged within the container and submerged in the water if the production of parahydrogen is also required. A second power supply provides a second pulsed signal to the coil through a switch to apply energy to the water. When the second power supply is disconnected from the coil by the switch and only the electrodes receive a pulsed signal, then orthohydrogen can be produced. When the second power supply is connected to the coil and both the electrodes and coil receive pulsed signals, then the first and second pulsed signals can be controlled to produce parahydrogen.
    Type: Grant
    Filed: June 25, 2002
    Date of Patent: September 14, 2004
    Assignee: Xogen Power Inc.
    Inventor: Stephen Barrie Chambers
  • Publication number: 20040157830
    Abstract: The present invention relates to novel compounds of formula (I), to a process for their menufacture, to pharmaceutical compositions containing them, and to their use in therapy, in particular their use in the prophylaxis and treatment of respiratory diseases.
    Type: Application
    Filed: March 5, 2004
    Publication date: August 12, 2004
    Inventors: Keith Biggadike, Rita Field, Stephen Barry Guntrip, Brian Edgar Looker
  • Patent number: 6767956
    Abstract: A process for producing an aqueous dispersion of a polymer in an aqueous medium having a viscosity below 10 Pa.s, in which the polymer is dispersed in an aqueous medium in an extruder at a temperature above 100° C., the pressure inside the extruder being maintained above atmospheric pressure so that the aqueous medium does not boil inside the extruder.
    Type: Grant
    Filed: March 11, 2003
    Date of Patent: July 27, 2004
    Assignee: Imperial Chemical Industries plc
    Inventors: Riaz Ahmad Choudhery, Kenneth Andrew Murray, Stephen Barry Downing, David John Southgate
  • Publication number: 20040099599
    Abstract: Methods and systems for treating a waste stream in a waste treatment system involve performing a unit process of the waste treatment system by contacting the waste stream with oxyhydrogen-rich gas generated on-site by an oxyhydrogen gas generator that implements water dissociation technology. In a preferred embodiment, the oxyhydrogen gas generator involves applying a pulsed electrical signal to a series of closely-spaced electrodes that are submerged in the waste stream to produce oxyhydrogen-rich gas from a water component of the waste stream. Operation of the oxyhydrogen gas generator in the waste stream may accomplish one or more unit processes for waste treatment, such as conditioning, stabilization, thickening, and dewatering, among others. At least a portion of the oxyhydrogen-rich gas can be conveyed for a second use in the waste treatment system, such as a source of combustible fuel for incineration or power generation, for example.
    Type: Application
    Filed: November 19, 2003
    Publication date: May 27, 2004
    Applicant: Xogen Power Inc.
    Inventors: Dave Van Vliet, Herbert Wallace Campbell, Stephen Barrie Chambers
  • Patent number: 6727256
    Abstract: Substituted heteroaromatic compounds of formula (I), wherein X is N or CH; Y is CR1 and V is N; or Y is N and V is CR1; or Y is CR1 and V is CR2; or Y is CR2 and V is CR1; R1 represents a group CH3SO2CH2CH2NHCH2—Ar—, wherein Ar is selected from phenyl, furan, thiophene, pyrrole and thiazole, each of which may optionally be substituted by one or two halo, C1-4alkyl or C1-4alkoxy groups; R2 is selected from the group comprising hydrogen, halo, hydroxy, C1-4alkyl, C1-4alkoxy, C1-4alkylamino and di[C1-4alkyl]amino; U represents a phenyl, pyridyl, 3H-imidazolyl, indolyl, isoindolyl, indolinyl, isoindolinyl, 1H-indazolyl, 2,3-dihydro-1H-indazolyl, 1H-benzimidazolyl, 2,3-dihydro-1H-benzimidazolyl or 1H-benzotriazolyl group, substituted by an R3 group and optionally substituted by at least one independently selected R4 group; R3 is selected from a group comprising benzyl, halo-, dihalo- and trihalobenzyl, benzoyl, pyridylmethyl, pyridylmethoxy, phenoxy, benzyloxy, halo-, dihalo- and trihalobenzy
    Type: Grant
    Filed: June 30, 2000
    Date of Patent: April 27, 2004
    Assignee: SmithKline Beecham Corporation
    Inventors: Malcolm Clive Carter, George Stuart Cockerill, Stephen Barry Guntrip, Karen Elizabeth Lackey, Kathryn Jane Smith
  • Patent number: 6723726
    Abstract: Substituted heteroaromatic compounds, and in particular substituted bicyclic heteroaromatic compounds of formula (I), wherein X is N or CH; A represents a fused 5, 6 or 7-membered heterocyclic ring containing 1 to 5 heteroatoms which may be the same or different and which are selected from N, O or S(O)m, wherein m is as defined above, the heterocyclic ring containing a total of 1, 2 or 3 double bonds inclusive of the bond in the pyridine or pyrimidine ring to which it is fused, with the provisos that the heterocyclic ring does not form part of a purine and that the fused heterocyclic ring does not contain two adjacent O or S(O)m atoms.
    Type: Grant
    Filed: June 30, 2000
    Date of Patent: April 20, 2004
    Assignee: SmithKline Beecham Corporation
    Inventors: George Stuart Cockerill, Malcolm Clive Carter, Stephen Barry Guntrip, Kathryn Jane Smith
  • Patent number: 6713485
    Abstract: The present invention relates to substituted heteroaromatic compounds, methods for their preparation, pharmaceutical compositions containing them and their use in medicine. Specifically, the invention relates to quinazoline derivatives useful in treating disorders mediated by protein tyrosine kinase activity, in particular erbB-2 and/or EGFR activity.
    Type: Grant
    Filed: February 8, 2002
    Date of Patent: March 30, 2004
    Assignee: SmithKline Beecham Corporation
    Inventors: Malcolm Clive Carter, George Stuart Cockerill, Stephen Barry Guntrip, Karen Elizabeth Lackey, Kathryn Jane Smith
  • Patent number: 6646041
    Abstract: An aqueous dispersion of particles of an addition polymer of ethylenically unsaturated monomers which dispersion also contains a stabilizing copolymer of a) weak acid containing species b) crosslinking species and optionally c) ethylenically singly unsaturated comonomers wherein the stabilizing copolymer contains at least 0.3% of crosslinking species.
    Type: Grant
    Filed: September 25, 2001
    Date of Patent: November 11, 2003
    Assignee: Imperial Chemical Industries PLC
    Inventors: Neal St. John Williams, Stephen Barry Downing
  • Publication number: 20030176564
    Abstract: A process for producing an aqueous dispersion of a polymer in an aqueous medium having a viscosity below 10 Pa.s, in which the polymer is dispersed in an aqueous medium in an extruder at a temperature above 100° C., the pressure inside the extruder being maintained above atmospheric pressure so that the aqueous medium does not boil inside the extruder.
    Type: Application
    Filed: March 11, 2003
    Publication date: September 18, 2003
    Inventors: Riaz Ahmad Choudhery, Kenneth Andrew Murray, Stephen Barry Downing, David John Southgate
  • Publication number: 20030176451
    Abstract: A process for the preparation of a compound of formula (I) 1
    Type: Application
    Filed: January 15, 2003
    Publication date: September 18, 2003
    Inventors: Malcolm Clive Carter, George Stuart Cockerill, Stephen Barry Guntrip, Karen Elizabeth Lackey, Kathryn Jane Smith
  • Publication number: 20030130408
    Abstract: An aqueous dispersion of particles of an addition polymer of ethylenically unsaturated monomers which dispersion also contains a stabilising copolymer of
    Type: Application
    Filed: September 25, 2001
    Publication date: July 10, 2003
    Applicant: Imperial Chemical Industries PLC
    Inventors: Neal St. John Williams, Stephen Barry Downing
  • Patent number: 6537326
    Abstract: A wool or the like fiber scour including at least one of the following, (a) scouring process wherein the fiber is subjected to an acid extraction process to remove absorbed iron, and by to greatly improve the brightness (Y tristimulus value) of the wool; (b) a scouring process wherein a bleaching process is carried out part way through the wet process following by dying, rewriting and chemical reduction, therefore stabilising the bleached color to prevent subsequent reversion in the dyebath; or (c) a scouring process wherein scoured clean fiber is dried and dusted, and then reimmersed in liquors containing detergents and dispersants, thereby effectively removing extra amounts of residual dirt. The scour produces an improved quality of fibres.
    Type: Grant
    Filed: July 5, 2000
    Date of Patent: March 25, 2003
    Assignee: Wool Research Organisation of New Zealand, Inc.
    Inventors: Alan John McKinnon, John Robert McLaughlin, Murray Edwin Taylor, Douglas Alexander Rankin, Paul Gregory Middlewood, Phillipa Le Pine, Paul Johannes Roy Mesman, Stephen Barry Manson
  • Publication number: 20020179453
    Abstract: An apparatus for producing orthohydrogen and/or parahydrogen. The apparatus includes a container holding water and at least one pair of closely-spaced electrodes arranged within the container and submerged in the water. A first power supply provides a particular first pulsed signal to the electrodes. A coil may also be arranged within the container and submerged in the water if the production of parahydrogen is also required. A second power supply provides a second pulsed signal to the coil through a switch to apply energy to the water. When the second power supply is disconnected from the coil by the switch and only the electrodes receive a pulsed signal, then orthohydrogen can be produced. When the second power supply is connected to the coil and both the electrodes and coil receive pulsed signals, then the first and second pulsed signals can be controlled to produce parahydrogen.
    Type: Application
    Filed: June 25, 2002
    Publication date: December 5, 2002
    Inventor: Stephen Barrie Chambers
  • Patent number: D528509
    Type: Grant
    Filed: July 22, 2005
    Date of Patent: September 19, 2006
    Assignee: Thomson Licensing, S.A.
    Inventors: Stephen Barry Chesebro, John Dan Mabry