Patents by Inventor Steven A. Kates

Steven A. Kates has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Automated allyl deprotection in solid-phase synthesis
    Patent number: 5861351
    Abstract: A method for removing an allyl protecting group from an allyl-protected derivative of a biologically relevant amino acid is disclosed. One relevant aspect of the method is the use of soluble organometallic catalyst, such as an organopalladium catalyst. Preferably, soluble tetrakistriphenylphosphine palladium (0) is used. The allyl deprotection method now disclosed is suitable for use on an instrument for automated peptide synthesis. Methods of preparing the soluble organometallic catalyst are also disclosed, as are soluble catalyst compositions.
    Type: Grant
    Filed: September 20, 1996
    Date of Patent: January 19, 1999
    Assignee: PerSeptive Biosystems, Inc.
    Inventors: Fernando Albericio, Steven A. Kates
  • Automated allyl deprotection in solid-phase synthesis
    Patent number: 5777077
    Abstract: A method for removing an allyl protecting group from an allyl-protected derivative of a biologically relevant amino acid is disclosed. One relevant aspect of the method is the use of soluble organometallic catalyst, such as an organopalladium catalyst. Preferably, soluble tetrakistriphenylphosphine palladium (0) is used. The allyl deprotection method now disclosed is suitable for use on an instrument for automated peptide synthesis. Methods of preparing the soluble organometallic catalyst are also disclosed, as are soluble catalyst compositions.
    Type: Grant
    Filed: February 20, 1997
    Date of Patent: July 7, 1998
    Assignee: PerSeptive Biosystems, Inc.
    Inventors: Fernando Albericio, Steven A. Kates