Abstract: A system and method are provided to detect target analytes based on magnetic resonance measurements. Magnetic structures produce distinct magnetic field regions having a size comparable to the analyte. When the analyte is bound in those regions, magnetic resonance signals from the sample are changed, leading to detection of the analyte.

Abstract: An interactive television program guide is provided. The interactive television program guide provides a user with the opportunity to select a language for playing television programming and displaying program guide text. Television program audio in the desired language may be obtained from a SAP or digital audio track and played in the selected language. Television related information in the desired language may be obtained from a digital track. If television program audio or related information is not provided in the selected language, the program guide may use a default language. The program guide may coordinate program guide display screen text with languages available for television programs when the programs are broadcast to users.

Abstract: An interactive television program guide is provided in which advertisements may be displayed on program guide screens. Banner advertisements may be displayed above and below program listings. Panel advertisements may be provided adjacent to program listings. The advertisements may contain video. The advertisements may be used to promote television programs and conventional goods and services. When a user selects an advertisement, the program guide provides the user with an opportunity to order products or services, request information, set reminders for upcoming programs, view program descriptions, record programs, or take other such actions. Embedded advertisements may be provided within the program listings region and may be automatically displayed immediately adjacent to related program listings.

Abstract: An air drying system for OBOGS is provided. The system comprises a bypass valve having an opened state and a closed state. The bypass valve is in fluid communication with an air inlet providing pressurized air. A dryer unit is configured to produce dried air when the bypass valve is in the closed state. An OBOGS unit produces oxygen enriched air while a purge valve has an opened state and a closed state. When the bypass valve is its closed state, the purge valve is in its opened state thereby directing a portion of the dried air to the oxygen generating system unit and a portion of the dried air to the dryer unit. When the bypass valve is its open state the pressurized air passes directly to the OBOGS unit.

Abstract: The present invention relates to pharmaceutical compositions comprising a compound of Formulas I and II, optionally in combination with a Compound of Formula III and/or a Compound of Formula IV. The invention also relates to solid forms and to pharmaceutical formulations thereof, and to methods of using such compositions in the treatment of CFTR mediated diseases, particularly cystic fibrosis.

Abstract: In one embodiment a vacuum assembly for an ion implanter system includes a first turbomolecular pump operatively coupled to a source chamber of the ion implanter system and a first backing line having a first end and a second end, the first end coupled to an exhaust port of the first turbomolecular pump, wherein the first turbomolecular pump and first end of the first backing line are configured to operate at a voltage potential of the source chamber. The vacuum assembly further includes a voltage insulator that is insulatively coupled to the first backing line, and a second turbomolecular pump operatively coupled to the first backing line, wherein the second turbomolecular pump is configured to operate at ground voltage potential.

Abstract: Disclosed herein are systems, methods, and non-transitory computer-readable storage media for managing a viral invitational content campaign. Invitational content is delivered with a user interface element that, upon selection, transmits a forwarding request to the content delivery server. The content delivery server generates a link with a unique identifier and creates a forwarding entry that includes the unique identifier and identifies the item of invitational content. The link is returned in response to the forwarding request. Upon selection of the link, a request including the unique identifier is transmitted to the content delivery server which accesses the corresponding forwarding entry to return the corresponding item of invitational content. A viral campaign dictates a target spend range and throttling methods are utilized to manage the spend. Invitational content forwarding, delivery cost, and content selection are variable to manage the spend. Calculated metrics are also used to manage spend.

Abstract: A building automation system may adjust operation of a building system based upon information regarding the relative location of one or more users of the building automation system. In some embodiments, a mobile device having location services for determining a location of the mobile device may provide this information. A mobile device may include a user interface, a memory for storing two or more predetermined geo-fences each defining a different sized region about a home of a user of the mobile device and a controller operatively coupled to user interface and the memory, the controller configured to accept a selection of one of the two or more predetermined geo-fences via the user interface. The controller may report when the location of the mobile device crosses the selected one of the two or more predetermined geo-fences to a remote device. Other geofencing approaches are also described.

Abstract: Provided herein are interlayer sheets formed of an acid copolymer composition, which comprises an acid copolymer resin or an ionomer that is the neutralized product of the acid copolymer resin. The acid copolymer resin comprises copolymerized units of an ?-olefin having 2 to 10 carbon atoms; about 10 to about 25 wt % of copolymerized units of a first ?,?-ethylenically unsaturated carboxylic acid having 3 to 10 carbon atoms; and about 15 to about 30 wt % of copolymerized units of a derivative of a second ?,?-ethylenically unsaturated carboxylic acid having 3 to 10 carbon atoms. In addition, the acid copolymer resin has a melt flow rate of about 1 to about 400 g/10 min. Light weight safety laminates comprising these interlayer sheets are characterized by good strength and superior acoustic damping, due to the properties of the acid copolymer composition.

Abstract: A wind power harvesting system includes a turbine having a bottom disk and a top disk and a first and a second panel of collapsible material each attached at a first end thereof to the bottom disk and at a second end thereof to the top disk. The combination of attached panels of material results in the formation of a Savonius shape that rotates in response to the force of the wind. A non-cogging generator is attached to the turbine to produce power therefrom.

Abstract: Biological samples of mammary fluid or components thereof are obtained using a breast pump device coupled with an absorbent paper or membrane, optionally facilitated by administering oxytocin to the subject. The breast pump device stimulates expression of mammary fluid and provides for collection of diagnostic samples on the absorbent paper or membrane to evaluate breast disease, including cancer. The biological sample may include fluid containing one or more of cells or cellular components, proteins, glycoproteins, peptides, nucleotides or other desired constituents comprising a breast disease marker. Absorbent paper or membrane, and methods relating to the paper or membrane, and a breast pump device are also provided.

Abstract: A valve assembly in an internal combustion engine fuel system includes a valve member movable within a valve body to contact a valve seat and block fluid communication between first and second passages. The valve seat and valve member each include a multi-layered coating having a harder metal nitride base layer and a softer metal nitride outer layer. The base layer is relatively incompliant to impacts between the valve member and the valve seat, and the outer layer is relatively compliant to the impacts and thereby deformable. Related methodology is disclosed.

Abstract: An apparatus and method are provided for operating a motor grader having steerable front wheels and a front and rear frame pivotally connected at an articulation joint. The method includes selecting an automatic articulation mode, and commanding front wheel steering to turn the motor grader, providing a plurality of front wheel steering corrections to an electronic controller, filtering the plurality of front wheel steering corrections using a method for filtering steering corrections based on the constant curve mode, wherein the method generates filtered front wheel steering corrections, and automatically commanding articulation of the front frame relative to the rear frame about the articulation joint in response to the filtered front wheel steering corrections.

Abstract: The present invention relates to crystalline solvate forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (Compound 1) and methods for their preparation. The present invention further relates to pharmaceutical compositions comprising the crystalline solvate forms, as well as methods of treatment therewith.

Abstract: A system and method used in the training of animals includes applying signals in two parts to the animal. The first part is a first conditioned stimulus cue signal having a first duration. The commencement of this signal is followed by the commencement of an unconditioned stimulus signal of a second duration. The commencement of the unconditioned stimulus signal may be either before the end of the first conditioned stimulus cue signal, simultaneous with the end of the first conditioned stimulus cue signal, or after a time interval of no signals between the end of the first conditioned stimulus cue signal and the commencement of the unconditioned stimulus signal. The signals may be electrical stimulation, vibration, sound, light, or odor. The first conditioned stimulus cue signal is used to catch the animal's attention; and the unconditioned stimulus signal is selected to be behaviorally significant to the animal for use in training of the animal.

Abstract: A tonneau cover apparatus for securing a flexible cover about a cargo box of a pickup truck. The apparatus comprises the cover and a support frame for attachment to the cargo box. The frame has two opposing side rails, each of which has a lock engaging surface. The support frame further includes a pair of securing plate engagement members, each of which is secured to one of the respective opposing side rails. The apparatus further comprises a flexible cover securing plate attached to the cover. The flexible cover securing plate includes a channel and least one locking member. Each locking member is secured within the channel and each respective locking member is engagable with the lock engaging surface of the respective side rail such that the flexible cover securing plate is prevented from disengaging with respect to the respective side rail when it is in a first position.

Abstract: A blood glucose monitor includes a can, a replaceable sensor cartridge that includes a frame, an upper spring disposed between the frame and the can, a case for housing the can and sealing the frame, a lower spring disposed between the can and the case, and a meter housing for sealing an upper portion of the frame. The can is capable of accepting the replaceable sensor cartridge. The frame of the removable cartridge has at least at least two walls defining a chamber for accepting a plurality of biosensors, and a bottom portion defining an opening and at least one sealing flange. The frame can further include a desiccant material capable of reducing humidity within the frame. The frame may be dimensioned such that an interference fit constrains the plurality of biosensors prior to inserting the frame within a blood glucose monitor.

Abstract: The disclosed watercraft hull has a flat pad keel whose width tapers towards the bow and its width at the transom is 15% to 25% of the hull's width at its chines. The hull is symmetric about its centerline, has a fine entry bow, a transom, and a pair of hard chines. Between the pad keel and the chines the hull has at least one pair of generally flat panels referred to herein as longitudinal steps having approximately 0 degrees of deadrize forming planing surfaces symmetrically located about the hull centerline. The hull also includes at least one pair of ultra high deadrize panels, outboard of and adjacent to the pad keel, located symmetrically about the hull centerline, and extending therefrom to the flat planing panels above them. The ultra high deadrize panels have a minimum average deadrize of approximately 50 degrees measured along their length.