Abstract: Method and device are provided for evaluating the pleural space. The device in introduced percutaneously into a pleural space. The device includes an energy detector that facilitates evaluation of the pleura. The device also includes a tissue collection component and a joint. The joint allows the device to be bent at least 120 degrees, facilitating assessment of the pleura. The device allows tissue sampling when the device is bent. The method encompasses selective tissue sampling of the parietal pleura without inducing pneumothorax, with its attendant extended recovery time, in the patient. The distal portion of the device is introduced percutaneously into the pleural space. The pleura near the access point is evaluated using an energy emitter and energy receiver integrated into the device and a portion of the parietal pleura near the access point is sampled using a biopsy tool integrated into the distal portion of the device.

Abstract: The present invention relates to pharmaceutical compositions comprising a compound of Formula I in combination with one or both of a Compound of Formula II and/or a Compound of Formula III. The invention also relates to solid forms and to pharmaceutical formulations thereof, and to methods of using such compositions in the treatment of CFTR mediated diseases, particularly cystic fibrosis.

Abstract: Systems, delivery devices, and methods to treat to ablate, damage, or otherwise affect tissue. The treatment systems are capable of delivering a coolable ablation assembly that ablates targeted tissue without damaging non-targeted tissue. The coolable ablation assembly damages nerve tissue to temporarily or permanently decrease nervous system input.

Abstract: Some embodiments relate to micro vias in printed circuit boards (PCBs). In an example, a PCB may include a PCB substrate and a micro via. The micro via may extend between opposing surfaces of the PCB substrate and may have a diameter less than or equal to about 100 microns. In another example, a method of forming micro vias in a PCB may include forming a through hole in a PCB substrate of the PCB. The method may also include positioning a pillar that is electrically conductive within the through hole. The method may also include backfilling the through hole around the pillar with an epoxy backfill.

Abstract: A portable device is used to aid a semi-truck driver in the repositioning of a tandem axle assembly of a trailer. The portable device may be easily attached and removed from the trailer's sub-frame during operation. The device will signal the driver visually when reaching the desired position during adjustment of the tandem axle assembly to a new location. The device may reduce time and increase safety for the driver during the tandem axle assembly repositioning operation. The device may be positioned at or near the desired tandem axle assembly position. A flap may pivotally hang in a position where a tire from the tandem axle assembly may deflect and pivot the flap when the tandem axle assembly reaches its desired position. A driver may see this flap deflection and know, with certainty, that they have achieved the desired tandem axle assembly position.

Abstract: The invention generally provides novel no-bake grain products and methods of preparation of the same. Specifically a no-bake food product with a toasted appearance and flavor and a method of providing a toasted appearance and flavor to a no-bake food product. The no-bake food product includes granola bars, clusters, cereal, instant hot cereal and snacks.

Abstract: The described system and method provides for the auctioning of radio presets in a vehicle and loading radio preset information into radio preset slots of the vehicle including different types of presets and different sets of preset information corresponding to different preset zones. Multiple auctions may be conducted for each vehicle or group of vehicles, and the auctions may be based on a variety of factors such as different types of presets, different preset zones, number of vehicles, type of vehicles, etc. Once the auction or auctions are won, radio preset slots corresponding to the results of the auctions may be loaded into vehicles at the manufacturer, dealership, or upon the occurrence of a geobox trigger when a vehicle is determined to be inside a particular preset zone.

Abstract: A system and method are provided for mounting, removing and retaining brake pads in disc brakes, such as air-operated disc brakes utilized on commercial vehicles, in a manner which does not require the use of separate brake pad retaining devices while providing positive retention of the brake pad. A preferred embodiment includes a brake caliper mount having brake pad abutment surfaces having radially-oriented and lateral grooves which permit a brake pad with corresponding projections on is lateral sides to be inserted through an opening of the brake caliper into the radially-oriented grooves until the backing plate projections are aligned with the lateral groove, and advancing the brake actuator behind the brake pad to place the brake pad in an operating position in which the actuator prevents the brake pad from realigning with the radially-oriented grooves until the actuator is retracted to permit brake pad extraction.

Abstract: A system for inspecting railroad ties in a railroad track includes a light generator, an optical receiver and a processor. The light generator is oriented to project a beam of light across the railroad track while moving along the railroad track in a travel direction. The optical receiver is oriented to receive at least a portion of the beam of light reflected from the railroad track and configured to generate image data representative of a profile of at least a portion of the railroad track. The processor is configured to analyze the image data by applying one or more algorithms configured to find boundaries of a railroad tie and determine one or more condition metrics associated with the railroad tie.

Abstract: Visually distinct, flaked Ready-to-Eat (“R-T-E”) cereal products with varied texture and thickness are produced by forming a cereal dough and forcing the same through an extrusion die assembly including various spaced openings which establish a plurality of dough streams which are merged prior to reaching a die outlet. Directly at the die outlet, a resulting dough extrudate is sliced by a cutter unit to form dough discs which are then dried and cooled, during which the discs curl and form cereal flakes having varying textures defined, at least in part, by distinct sets of surface bumps. The number and configuration of the bumps can be altered by changing the number, shape and/or position of the various spaced openings of the die assembly, while the thicknesses of the resulting cereal flakes can be varied by just altering an operational speed of the cutter unit.

Abstract: A system is disclosed for repairing and reconstructing an injured intra-articular, extra-articular ligament or tendon to a bone. The system includes realigning the axis of a bone, and further includes fixing fragments of a bone together. Novel devices, instruments and methods are disclosed, including a cortical loop for engaging a bundle of soft-tissue and capturing the bundle against a bone surface, an anchor for stabilizing a fractured bone, a guide for directing an orthopedic blade, and a hinged external jig arranged to position and guide the blade. Methods are disclosed for connecting soft-tissue to a bone and for bone alignment.

Abstract: In some embodiments, the present invention provides an apparatus and process that includes control electronics that generate an electronic control signal; and a plurality of optically or electrically pumped semiconductor lasers, quantum-cascade lasers, optical parametric generators, or optical parametric oscillators, operatively coupled to the control electronics, that output an optical signal having a plurality of wavelengths, each wavelength having an output intensity that each of which is varied over time to simulate a combustion signature of a weapon. In some embodiments, the optical signal includes at least two different infrared wavelengths that are varied differently with time.

Abstract: A hand exerciser device that includes a body having a thumb opening and a plurality of finger openings spaced apart from the thumb opening. Between the finger openings and the thumb opening, there is provided at least one and preferably a corresponding number of projections, which can be independently depressed and manipulated by the fingers.

Abstract: A point of sale device includes a card mounted on a hanger on a vertically extending mounting structure of a retail shop. The card carries a reusable storage container in which articles are stored. The container includes a body with an opening closed by a transparent, sealable, removable and re-sealable lid. The container is mounted on the card and the device is mounted on the hanger so a prospective purchaser can see the articles through the transparent lid. In one embodiment, the body includes a permanent magnet abutting the base.

Abstract: An integrated-testing system includes a meter, a lancing device and a storage case. The meter includes a housing, a display and a processor. The storage case holds the meter and the lancing device in a relatively fixed position to each other. The meter and the lancing device are maintained in the storage case in the relatively fixed position until a fluid sample is desired, at which time a first portion of the lancing device is advanced to a position external to the storage case to obtain the fluid sample and a second portion of the lancing device remains relatively fixed in the storage case while the fluid sample is obtained.

Abstract: A package having an additive that does not adhere to a medical device enclosed therein.

Abstract: Optimizing an I2C bus frequency, the bus including signal lines coupling a master and slave nodes, a signal line coupled to a rise time detection circuit monitoring a voltage of the signal line, the voltage alternating between a logic low and logic high, where optimizing the frequency includes: detecting, during a rise in the signal line, a first voltage, the first voltage being greater than the logic low voltage; starting a counter to increment once for each clock period of the circuit; detecting a second voltage on the signal line, the second voltage greater than the first and less than the logic high; stopping the counter; calculating, in dependence upon the clock period and the counter value, a rise time; determining whether the rise time is greater than a maximum threshold; and increasing the I2C bus frequency if the calculated rise time is greater than the maximum threshold.

Abstract: A method of grouping multiple waveforms for a single channel of acquired data on a display area uses a graphic icon with the display area. The graphic icon has a first portion with a symbol indicating the single channel and with an indicator defining a baseline for the display area. The graphic icon also has a second portion with symbols indicating which of the multiple waveforms currently are being displayed. The symbol for the single channel and the symbol for a selected one of the multiple waveforms currently being displayed are highlighted. The highlighting may be via color, where the highlight color corresponds to the color of the waveforms currently being displayed.

Abstract: Recombinant constructs and methods useful for improvement of plants are provided. In particular, recombinant constructs comprising promoters functional in plant cells positioned for expression of polynucleotides encoding starch branching enzymes from microbial sources are provided. The disclosed constructs and methods find use in production of transgenic plants to provide plants, particularly crop plants, having improved yield.

Abstract: A low-power diversity receiver includes at least two receive paths, each of which is designated as a primary or secondary receive path. A primary receive path is compliant with system requirements (e.g., IS-98D requirements). A secondary receive path is not fully compliant with the system requirements and is designed for lower power, less area, and lower cost than the primary receive path. For a multi-antenna receiver, the two receive paths may be used to simultaneously process two received signals from two antennas. For a single-antenna receiver, either the primary or secondary receive path is selected, e.g., depending on whether or not large amplitude “jammers” are detected, to process a single input signal from one antenna. The receiver may include additional receive paths for additional frequency bands and/or GPS.