Abstract: A method and apparatus for in vivo electroporation therapy. Using electroporation therapy (EPT) as described in the invention, tumors treated by a combination of electroporation using the apparatus of the invention and a chemotherapeutic agent caused regression of tumors in vivo. In one embodiment, the invention provides a method of EPT utilizing low voltage and long pulse length for inducing cell death. One embodiment of the invention includes a system for clinical electroporation that includes a needle array electrode having a “keying” element that determines the set point of the therapy voltage pulse and/or selectable array switching patterns. A number of electrode applicator designs permit access to and treatment of a variety of tissue sites. Another embodiment provides a laparoscopic needle applicator that is preferably combined with an endoscope for minimally invasive EPT.

Abstract: In-laid metallization patterns, e.g., of copper or copper alloy, are formed in the surface of a dielectric layer with significantly improve reliability by voidlessly filling recesses formed in the dielectric layer surface by electroplating. Embodiments include preventing “pinching-off” of the recess opening due to overhanging nucleation/seed layer deposits at the corners of the opening as a result of localized increased rates of deposition. Further embodiments include providing a dual-layered dielectric layer comprising different dielectric materials and performing a first, isotropic etching process of the upper lamina of the dielectric layer for selectively tapering the width of the recess mouth opening to provide a wider opening at the substrate surface, followed by a second, anisotropic etching process for extending the recess at a substantially constant width for a predetermined depth into the lower lamina of the dielectric layer.

Abstract: An apparatus for separating a suspension, comprising a collection vessel; and a cyclone fixably received within the collection vessel, the cyclone having an inlet for receiving the suspension, a wall having at least a filter medium for separating the suspension into at least two components, and a lower underflow outlet for dispensing one of the two components, wherein the filter medium is porous and in communication with a catalyst, a hydrophillic, or hydrophobic material.

Abstract: Upon detection of systole by a detector (21), a master controller (20) adjusts a transmit level control (36) to cause a transducer array (2) to transmit ultrasound waves with a high acoustic output approaching the mechanical index FDA limit with sufficient dwell time between HAO frames to limit the temporal average below the FDA limit. The dwell time may be occupied by lower acoustic output frames (LAO) which are generated using the transmit level control (36).

Abstract: Access to an operator station of a large track-type tractor is provided by a ladder support structure pivotally attached to a portion of the radiator guard of the tractor. The ladder support structure extends over a track of the tractor and has a ladder pivotally attached to a distal end of the ladder support structure that provides steps over a push arm and a tilt cylinder of the tractor. When the ladder assembly is moved to its carry position, the ladder is moved to a position inside the ladder support structure, and the ladder support structure raised to a vertical position adjacent a side panel of the radiator guard of the tractor. The present invention avoids the problem of machine operators climbing on the push arms, tilt cylinders, radiator, radiator guard, track, hood, and engine enclosures in order to gain access to the operator station.

Abstract: Disclosed are improved methods for preparing a grain based extrudate involving high screw speeds, short barrel length extruders and short residence times. Preferred methods of preparation reside in methods for preparing the present improved RTE cereal or snack products. The preferred methods contain the steps in sequence of feeding an at least partially ungelatinized grain based material to a cooker extruder having at least one rotating screw, said cooker extruder including a barrel preferably having a relatively short length to diameter (“L/D”) ratio of substantially less than 12; working the grain based material by rotating the screw at a rotational speed of at least 700 rpm to mix and heat the cereal material and to compress the grain based material; and extruding the plasticized mass through at least one die orifice to form an extrudate. Its preferred product aspect provides RTE cereal or snack products in the form of a puffed grain based product piece having a density of about 10 to 100 g/l.

Abstract: A transducer is described especially for use in providing acoustic transmission in a borehole. The transducer includes a multiple number of magnetic circuit gaps and electrical windings that have been found to provide the power necessary for acoustic operation in borehole while still meeting the stringent dimensional criteria necessitated by boreholes. Various embodiments conforming to the design are described. Moreover, the invention includes transition and reflector sections, as well as a directional coupler and resonator arrangement particularly adapted for borehole acoustic communication.

Abstract: Polypeptides and polynucleotides useful for detecting, diagnosing, staging, monitoring, prognosticating, in vivo imaging, preventing or treating, or determining the predisposition of an individual to diseases and conditions of the urinary tract, such as urinary cancer, are described. These sequences are derived from keratin/cytokeratin, CAS, or mat-8 polypeptides and polynucleotides. Also provided are antibodies which specifically bind to keratin/cytokeratin, CAS, or mat-8-encoded polypeptides or proteins, which molecules are useful for the therapeutic treatment of urinary tract diseases, tumors or metastases.

Abstract: The formation and/or growth of dendrites emanating from Cu or Cu alloy lines into a bordering open dielectric field are prevented or substantially reduced by chemically removing a portion of the surface from the dielectric field and from between the lines after CMP with a solution comprising HF and H2O. Embodiments include removing up to 50 Å of silicon oxide by treating the wafer in a spray acid processor with a solution containing HF and deionized water at a water to acid ratio of about 100:1 to about 250:1.

Abstract: A picture hanger is initially held in place on a wall in a temporary manner without damaging the wall by including a backing with a shock absorbing layer overlaid by a temporary adhesive film. Prior to the picture hanger being temporarily fastened to the wall, the temporary adhesive film is covered by a protective paper sheet. The shock absorbing layer prevents the wall from being indented when the hanger is permanently secured to the wall by hammering a pin or nail through the layer and film. The layer is sufficiently soft to hold the nail in place when the nail impales the layer prior to hammering the nail into the wall. Prior to the backing being secured to the hanger, the permanent adhesive film is overlaid by another removable protective sheet. Initially the backings are located on an elongated strip and are punched from the strip for mounting on the hook body.

Abstract: An electrophoresis container apparatus having (1) a primary container tray made from a UV light transmitting materials, (2) a UV light transmitting gel contained in the primary container tray, and (3) a removable top sheet for covering the gel. The removable top sheet may also be UV light transmitting. The apparatus optionally comes with a handle having pincers for grasping the primary container and permitting easy movement of the apparatus from location to location. Because the apparatus transmits UV light, the gel can be used and analyzed while it is still in the tray. This eliminates the need to remove the gel before analysis and reduces the chances that the gel will be damaged during handling. Similarly, because the apparatus has an optional handle, the user can move the apparatus form location to location without touching the apparatus and exposing the user to dangerous chemicals, e.g., those often used in staining procedures.

Abstract: A table assembly consists of a table top supported by a leg assembly, which includes a vertical tubular leg member. The leg assembly further includes a foot member mounted to the lower end of each leg via a mounting member. The length of the foot member can be varied according to the width of the table top to selectively provide different sizes of tables according to user requirements, while the mounting member is usable for all sizes of legs and foot members to mount the foot member to the leg. A power/communication housing is mounted to the underside of the table top. The housing includes first and second passages isolated from each other via a wall, with power supply cabling and communication cabling placed within the first and second passages, respectively.

Abstract: The present invention provides a heat sink that, in an advantageous embodiment, includes a spine having a width with first and second opposing sides that are oriented to be abnormal to the substrate when the heat sink is mounted on the substrate. The heat sink further includes an electronic device support leg that extends generally transverse from the first side and that is configured to support a heat generating electrical component thereon. Alternative embodiments of the present invention may include a plurality of such electronic device support legs. A plurality of cooling fins are also included in the present invention, extending from the second side. Moreover, each of the plurality of cooling fins has a depth that is substantially less than the width of the heat sink, which give this unique heat sink an exceptional cooling efficiency. In particular advantageous embodiments, the depth to width ratio of the fins and spine, may range from about 1 to 5 or 1 to 10, respectively.

Abstract: An antenna array portion of a communication device receives a desired signal and an interfering signal. The unweighted desired and interfering signals from a first antenna (302) are then combined in a summer (308) with weighted versions of the signals from a second antenna (304) to produce a received RF signal (312). The signal-to-noise ratio (SNR) of the received RF signal (312) is then estimated using a spectral analysis technique. This estimate, along with the complex weights applied to the signal from the second antenna, is then stored. Utilizing feedback and a methodology for searching through a range of sets of complex weights, the weights optimizing the SNR are determined and used to weight subsequent signals from the second antenna.

Abstract: The formation and/or growth of dendrites emanating from Cu or Cu alloy lines into a bordering open dielectric field are prevented or substantially reduced by chemically removing a portion of the surface from the dielectric field and from between the lines after CMP by double sided scrubbing with a chemical agent. Embodiments include removing portions up to 60 Å of silicon oxide by double sided scrubbing with a solution containing ammonium fluoride, diammonium hydrogen citrate, triammonium citrate, and dionized water, with or without a surfactant.

Abstract: A method for improving the corrosion resistance, increasing the hardness, providing superior ductility, and reducing surface-cracking of a diffusion coating by nitriding and heating-treating the diffusion coating is disclosed. The nitriding and heat-treating may occur subsequently or simultaneously. Further, the disclosed method may be practiced subsequent to or incorporated as an intergral part of any known diffusion coating process which utilizes a heating step in a furnace having a cover gas.

Abstract: A pre-slit injection site (34) includes a housing (40) with a flow path therethrough. A first end (42) of the housing (40) carries a pre-slit septum (52). One form of a blunt cannula (98), usable with the injection site (34), carries a locking member (100). When the pre-slit injection site (34) slidably receives the blunt cannula (98), the locking member (100) latches to the injection site (34) and creates a mechanically coupled unit. Another form of the cannula (280) includes a tube having a tapered distal end region (298) and having elongate discharge slots (294) for reducing contact surface area and for directing the flow laterally out of the cannula. The cannula may also include a rounded lead post (330), an annular barb (394), and axially oriented grooves (268).

Abstract: A method and apparatus for improved concurrency within a video graphics process by generating culling information from geometry information. The geometry information corresponds to an image to be rendered, and the culling information indicates the triangles of the objects of the image that are in a front-facing or back-facing position. Having generated the culling information, set-up information is generated therefrom. The set-up information provides rendering data for the triangles of the object of the image being rendered. Next, pixel data is generated for a triangle based on the set-up information. To improve the concurrency, the queuing and the retrieval of the culling information and the set-up information from non-local memory are controlled such that the generating of the culling information, the set-up information, and the pixel data is done with improved concurrency.

Abstract: A lapping guide for use in fabrication of a device includes a first resistive element and a second resistive element. The two resistive elements can provide different changing resistances throughout the lapping of the device. These two resistances can be used throughout the lapping of the device to facilitate determination of when a predetermined desired height of the device has been achieved, and therefore stop the lapping of the device. The resistive elements can be physically adjacent to each other or separate from each other. Further, a common lead can be electrically connected to both resistive elements for measuring their respective resistances. In addition, the resistive elements can be separated from each other by the device.

Abstract: An emergency brake lock assembly that locks an emergency brake actuator in an engaged position to prevent the vehicle from moving while a lift assembly contained on the vehicle is being operated. The emergency brake lock assembly includes an emergency brake switch that is positioned to detect movement of the emergency brake actuator between an engaged position and a disengaged position. When the emergency brake actuator is in the engaged position, the emergency brake switch generates a brake engaged signal. An auxiliary door switch is positioned to detect the movement of an auxiliary door contained on the vehicle. When the auxiliary door opens, the auxiliary door switch generates a door open signal. Upon receiving both the door open signal and the brake engaged signal, a solenoid actuator moves a locking member to a locked position to retain the emergency brake actuator in the engaged position.