Abstract: An electronic device can include a housing defining an aperture and a display assembly at least partially positioned in the aperture. The display assembly can include a substrate having a conductive portion, a display layer having pixels, a touch sensitive layer positioned on a first side of the substrate, an operational component positioned on a second side of the substrate opposite the first side, and a flexible electrical connector electrically coupled with the conductive portion and the operational component. The flexible electrical connector can include an electromagnetic antenna. A transparent cover can overlay the display assembly and can be secured to the housing.

Abstract: Provided are methods of treating an HHLA2-bearing tumor in a subject with a fusion protein comprising an IgV-like domain of a TMIGD2 sufficient to treat the HHLA2-bearing tumor. A fusion protein comprising an IgV-like domain of a TMIGD2 and related compositions and encoding nucleic acids are also provided.

Abstract: An automated analyzer that receives samples prepared for analysis in an automated pre-analytical module and a method of operation of such automated analyzer. The automated analyzer includes a shuttle transfer station that receives a shuttle carrier from the automated pre-analytical system. The shuttle transfer station has a clamping assembly for the shuttle. The clamping assembly has jaws that advance engagement members into contact with a bottom portion of sample containers disposed in the shuttle. The clamping assembly secures the sample containers in the shuttle when sample is aspirated from the sample containers. The automated analyzer also has a multichannel puncture tool that is adapted to be carried by a robotic gripper mechanism. The multichannel puncture tool has multiple puncture members that each defines a channel. Each channel is in communication with a different trough in the consumable. A pipette can pass through the channel in the puncture tool.

Abstract: To produce a bacterial microcompartment shell, or a designed shell based on naturally occurring bacterial microcompartment shells in a new host organism, a synthetic operon is constructed that contains the desired shell protein genes and translation efficiency is controlled by host specific ribosomal binding sites. Proteins or other molecules can be encapsulated in the microcompartment shells by various methods described herein. The constructs can also be used to express self-assembling sheets comprised of shell proteins.

Abstract: Described herein are methods and apparatus for constructing tissue replacements, such as bone replacements that may be used to repair damaged or missing segments of bone, such as may occur in wound repair or as a repair of a congenital anomaly. These methods involve a three-dimensional (3D) cell growth medium made from a yield stress material that allows cells and structures to be easily deposited and positioned.

Abstract: A tester apparatus is described. Various components contribute to the functionality of the tester apparatus, including an insertion and removal apparatus, thermal posts, independent gimbaling, the inclusion of a photo detector, a combination of thermal control methods, a detect circuitry in a socket lid, through posts with stand-offs, and a voltage retargeting.

Abstract: A telecommunications assembly includes a chassis and a plurality of fiber optic splitter modules mounted within the chassis. Each splitter module includes at least one fiber optic connector. Within an interior of the chassis are positioned at least one fiber optic adapter. Inserting the splitter module through a front opening of the chassis at a mounting location positions the connector of the splitter module for insertion into and mating with the adapter of the chassis. The adapters mounted within the interior of the chassis are integrally formed as part of a removable adapter assembly. A method of mounting a fiber optic splitter module within a telecommunications chassis is also disclosed.

Abstract: A cell processing system includes a processor connectable to a source container filled with a biological fluid, the processor including a separator configured to separate the biological fluid from the source container into at least two streams according to a process including at least one process parameter, and a controller coupled to the processor and an input. The controller is configured to receive the at least one process parameter, to evaluate the process using the at least one process parameter before performing the process, and to carry out one or more actions based on the evaluation, such as providing an output estimate to the operator, preventing the process from being performed according to a comparison between a calculated condition and a control, or providing an error indication to the operator according to the calculated condition and a measured in-process condition.

Abstract: An electronic watch may include a housing defining a side wall having a through-hole and a crown assembly including an actuation member. The actuation member may include a crown shaft extending through the through-hole and having an exterior portion defining an input surface and a crown ring coupled to the exterior portion of the crown shaft and electrically isolated from the crown shaft. The crown assembly may further include an optical encoder component attached to the actuation member and defining a group of optical features. The electronic watch may further include an optical detector configured to detect rotation of the crown assembly by detecting motion of the group of optical features and an electrocardiograph sensor comprising a sensing component. The sensing component may be conductively coupled to the actuation member via a conductive path at least partially defined by the crown shaft.

Abstract: Described herein is a bounce-reducing cover assembly that is positioned on the top of the cover and riser of a sprinkler to achieve a similar golf ball bounce characteristic as typical golf course turf. The cover assembly has a top surface that is composed of a plurality of vertical fingers or posts, which help achieve the desired bounce characteristics with a golf ball. Specifically, these fingers are flexible and provide some “give” so as to absorb some of the force from an incoming golf ball. Depending on the durometer of the material, size of the fingers, and spacing of the fingers, different bounce characteristics can be achieved.

Abstract: A pulsation dampener for a dispensing system comprising a housing, a diaphragm comprising at least one fluoropolymer layer, the diaphragm dividing the housing into a first compartment and a second compartment, an inlet port and an outlet port each in fluid communication with the first compartment thereby providing a flow path for a liquid to enter the first compartment via the first inlet port and exit the first compartment via the outlet port, and at least one gas disposed within the second compartment, the at least one gas having a kinetic diameter of 0.36 nm or greater, wherein the fluoropolymer of the at least one fluoropolymer layer and the at least one gas are selected such that a gas transmittance rate of the at least one gas through the diaphragm is from 0 mbar*L/second to 1*10?5 mbar*L/second.

Abstract: A method of inspecting a dispenser including a faceplate comprises translating a sensor across the faceplate while measuring a distance between the sensor and the faceplate. The sensor is oriented such that a longitudinal axis of the sensor extends at an acute angle relative to a longitudinal axis of the faceplate. The method may include translating another sensor across the faceplate while measuring the same distance. Or the method may include another translating of the sensor across the faceplate while measuring the same distance. In either case, the sensor is oriented such that the longitudinal axis of the sensor extends at an obtuse angle relative to the longitudinal axis of the faceplate. The method includes determining, based on the measured distances, whether an amount of accumulated formable material on the surface of the faceplate is greater than a predetermined value.

Abstract: A method of forming an electronic device is disclosed. The method comprises forming a barrier layer on a silicon layer, and depositing a silicon oxide layer on the barrier layer. The formation of the barrier layer on the silicon layer minimizes parasitic oxidation of the underlying silicon layer and minimizes defects in the silicon layer.

Abstract: An optical power detection system comprises a sensor and a reader. The sensor is configured to detect light in the cladding of an optical fiber. The sensor is positioned both within a ferrule of the optical fiber and proximate the cladding. The sensor is additionally configured to produce an output signal representative of the detected light. The reader is electrically coupled to the sensor and is configured to receive the sensor output signal. The reader is additionally configured to operation on the output signal to produce a corresponding visual and/or audible indication of the optical power in the optical fiber.

Abstract: A modular shipping container includes a layer of two side pieces positioned against sides of a component of several components with a same width. The side piece include pegs protruding from a top of each side piece and bottom openings in a bottom of each side piece sized and positioned to conform to the pegs. The container includes one or more end pieces on the same layer as the side pieces. Each end of the end piece is shaped to attach to an end of a side piece and is shaped to maintain a width between the side pieces. A length of an area formed by the side pieces and end pieces is sized to accommodate a maximum length of each component. The components have a height that is an integer number of standard units and a height of the side pieces matches an integral number of the standard units.

Abstract: A cell processing system includes a processor connectable to a source container filled with a biological fluid, the processor including a separator configured to separate the biological fluid from the source container into at least two streams according to a process including at least one process parameter, and a controller coupled to the processor and an input. The controller is configured to receive the at least one process parameter, to evaluate the process using the at least one process parameter before performing the process, and to carry out one or more actions based on the evaluation, such as providing an output estimate to the operator, preventing the process from being performed according to a comparison between a calculated condition and a control, or providing an error indication to the operator according to the calculated condition and a measured in-process condition.

Abstract: A multicomponent bridge support system includes: a base portion configured to make contact with bearing soil/strata/bedrock; a support portion configured to engage a bridge deck; and one or more precast intermediate portions configured to space the support portion with respect to the base portion.

Abstract: An inline adapter is provided including an elongated hollow body having an open first end configured to be connected to an inspiratory port of a patient ventilation assembly, an open second end opposite the first end, and a sidewall extending therebetween defining an airflow channel. The adapter also includes an inhaler port extending from the open second end of the adapter body configured to be connected to an inhaler, and an inspiratory branch having an open first end extending from an opening in the sidewall of the adapter body and an open second end configured to be connected to an inspiratory limb of the ventilation assembly. A longitudinal central axis of the inspiratory branch is angled relative to a longitudinal central axis of the adapter body.

Abstract: An automated pre-analytical processing method and an apparatus for pre-analytical processing of samples to be forwarded to an adjacent analyzer for analysis. Rack label information is read and communicated to a processor. From the rack label information, the processor determines where to route the rack. The pre-analytical system has a rack robot that conveys racks to discrete locations depending upon the routing information assigned to the rack by the processor. The pre-analytical system has an automated station that reads the labels of individual sample containers in the rack that are brought to the automated station on instructions from the processor. Depending on the type of sample container and the type of sample disposed therein, the samples are either prepared for analysis by the automated station or the sample containers are directly passed through the automated station. Prepared samples and passed through samples are passed individually to a batching rack.

Abstract: A pressure regulator module for a chip-based microfluidic platform is provided. The module includes a microfluidic channel for passing flowable material from the inlet region through the outlet region and into a downstream compartment; one or more microvalves fluidly connected to the microfluidic channel and upstream of the outlet region; and one or more reservoirs fluidly connected to the microvalves, for receiving flowable material diverted by the microvalves, where a flow of flowable material passing from the inlet region toward the downstream compartment is at least partially diverted by the microvalves into the reservoirs as a result of a pressure increase in the microfluidic channel. In some versions, the microvalves are capillary burst valves. A microfluidic chip containing the module and a method of using the module are provided.