Abstract: The present invention sets forth a technique for performing automated motion adaptation in an animated sequence. The technique includes generating a set of one or more motion sequences based on motion capture data and selecting one of the set of motion sequences based on a score function value. The technique also includes adapting the selected motion sequence such that the adapted motion sequence, when applied to an animation character model, causes the animation character model to move from a specified starting position associated with the animation character to a specified goal position associated with the animation character.

Abstract: Embodiments of the invention relate to a computer-implemented method and system for generating personalized recommendations for a target user based at least on stored data about the target user. The method comprises obtaining, at the server computer, data from a plurality of data sources, including entity data associated with a plurality of entities, stored in an entity database, or personal data associated with a plurality of users, stored in a user database. The personalized recommendations system then merges the entity data or personal data and maps the entity or personal data to a corresponding entity or target user, respectively. The entity or personal data is differentiated, a relevance is determined, a weight is assigned to the data and corresponding source to canonicalize the data, the respective databases are updated with the corresponding data, and then a set of personalized recommendations to the target user is generated using the updated databases.

Abstract: Implantable devices for fixation of curved bone such as the pelvic ring pubic symphysis and acetabulum, and methods for the use of the devices are disclosed. The implantable devices are convertible between a flexible state and a rigid state, and include an elongate structure having a proximal bone interface, a main body, and a distal bone interface. In a flexible state, the devices may be inserted along, and conform to a curved pathway, and in the rigid state, the devices may support the mechanical loads required to fixate a fracture.

Abstract: A microwell array specifically designed for culturing organoids is provided along with a system to enable automated imaging, identification, and isolation of individual organoids. The microwells of the microarray include a releasable cellraft that enables the automated release and transfer of selected organoids present on the cellrafts to a separate collection plate. Organoids grown on the microarray can be reliably tracked, imaged, and phenotypically analyzed by the instrument system in brightfield and fluorescence as they grow over time, then released and transferred fully intact for use in downstream applications. The use of the system is demonstrated using mouse hepatic and pancreatic organoids for single-organoid imaging, clonal organoid generation, parent organoid subcloning, and single-organoid RNA extraction for downstream gene expression or transcriptomic analysis.

Abstract: Image contrast of a projected image on a screen can be adjusted by configuring a lens aperture element in a projector. A projector can be set in a theatre to emit projected light representing the projected image onto the screen. The projected image can be projected onto the screen in the theatre such that a light level of the projected light is at a target light level. The lens aperture element in a projection lens of the projector can be configured to change an image contrast of the projected image. In response to inserting the lens aperture element, a setting for a light emitter in the projector can be adjusted such that the light level of the projected light is at the target light level.

Abstract: A microwell array specifically designed for culturing organoids is provided along with a system to enable automated imaging, identification, and isolation of individual organoids. The microwells of the microarray include a releasable cellraft that enables the automated release and transfer of selected organoids present on the cellrafts to a separate collection plate. Organoids grown on the microarray can be reliably tracked, imaged, and phenotypically analyzed by the instrument system in brightfield and fluorescence as they grow over time, then released and transferred fully intact for use in downstream applications. The use of the system is demonstrated using mouse hepatic and pancreatic organoids for single-organoid imaging, clonal organoid generation, parent organoid subcloning, and single-organoid RNA extraction for downstream gene expression or transcriptomic analysis.

Abstract: Systems and methods for intermedullary bone fracture fixation are described herein. The fixation device includes a main body having a flexible state and a rigid state. The fixation device further includes a proximal interface coupled to a proximal end of the main body to anchor the fixation device to an exterior surface of the bone and a distal interface coupled to a distal end of the main body to anchor the fixation device to an interior cavity of the bone. The fixation device further includes a locking interface to configured to convert the main body from the flexible state to the rigid state.

Abstract: A nasal cannula arrangement for use as part of systems for delivery respiratory gases to a patient is disclosed. The nasal cannula arrangement includes a manifold part adapted to receive gases from a delivery conduit. The manifold includes one but preferably a pair of prongs extending upward and curving towards the rear of the manifold. The prongs are inserted into the nostrils of the patient and deliver gases to a patient. The prongs have a cut out on the rear side of the prongs. The cut out forms a gases outlet in the prongs and are shaped such that the area of the cut out area is greater than the cross sectional area of the prongs at the entry point to the prongs.

Abstract: A blow mold assembly for forming a polymeric container. The blow mold assembly has a thread insert defining threads configured to form finish threads on a finish of the polymeric container. An electric heater of the blow mold assembly is configured to heat the thread insert as the polymeric container is formed.

Abstract: A method (200) for determining a position and an orientation of a portion of a handheld personal care device relative to a user's body (50), comprising: providing (210) a handheld personal care device comprising at least one energy source (20) and at least one detector (22), both the at least one energy source and the at least one detector located within the handheld personal care device, the at least one energy source arranged at a first position and having a first orientation within the handheld personal care device; emitting (220) energy in a three dimensional space surrounding the handheld personal care device; detecting (230) a portion of the energy emitted; generating (240) sensor data; extracting (250) one or more features from the generated sensor data; and estimating (260) a position and an orientation of a portion of the handheld personal care device relative to the user's body based on the extracted one or more features.

Abstract: A system for simultaneously forming and filling a polymeric container with a product. The system includes a mold defining a container profile and a mold vacuum vent extending from the container profile to an upper surface of the mold. A striker plate is secured to the upper surface of the mold. The striker plate defines a striker vacuum vent that aligns with the mold vacuum vent to allow some of the product to be pulled by vacuum out of the mold through the mold vacuum vent and the striker vacuum vent.

Abstract: A system (100) for detecting tissue inflammation, and gingivitis specifically, including a light emitter (102) configured to emit light at a tissue region (104) within a user's mouth; a light detector (106) configured to detect optical signals diffusely reflected through the tissue region over a period of time; a controller (130) configured to: determine a slope signal (Q) based on at least two signals (R(?1), R(?2)) from the optical signals, the at least two signals including at least one signal from a hemoglobin-dominated wavelength range; determine one or more characteristics of the slope signal; and select a best measurement signal based on the one or more characteristics of the slope signal. The system further includes a user interface (116) configured to provide information regarding a position of a probe for accurate detection of tissue inflammation based on the one or more characteristics of the slope signal.

Abstract: A nasal cannula arrangement for use as part of systems for delivery respiratory gases to a patient is disclosed. The nasal cannula arrangement includes a manifold part adapted to receive gases from a delivery conduit. The manifold includes one but preferably a pair of prongs extending upward and curving towards the rear of the manifold. The prongs are inserted into the nostrils of the patient and deliver gases to a patient. The prongs have a cut out on the rear side of the prongs. The cut out forms a gases outlet in the prongs and are shaped such that the area of the cut out area is greater than the cross sectional area of the prongs at the entry point to the prongs.

Abstract: A projection system includes a projection lens to project image light along an image light path towards a port window and to redirect a portion of the image light away from the image light path as result of being scattered or reflected away from the image light path. The projection system includes a port window for transmitting projected image light from the projection lens. The port window has a surface for redirecting a portion of the projected image light as result of being scattered or reflected away from the image light path. The projection system includes an enclosure positioned between the port window and the projection lens to surround the image light path between the port window and the projection lens. The enclosure absorbs the portion of the image light redirected by the projection lens and absorbs the portion of the projected image light redirected by the surface.

Abstract: The present disclosure includes a thread insert for a blow mold assembly configured to form a polymeric container. The thread insert includes: an inner mold surface defining threads, the inner mold surface configured to form a finish of the container; a first bore defined by the thread insert; and a first heating element seated within the first bore and configured to heat the inner mold surface.

Abstract: Systems and methods for intermedullary bone fracture fixation are described herein. The fixation device includes a main body having a flexible state and a rigid state. The fixation device further includes a proximal interface coupled to a proximal end of the main body to anchor the fixation device to an exterior surface of the bone and a distal interface coupled to a distal end of the main body to anchor the fixation device to an interior cavity of the bone. The fixation device further includes a locking interface to configured to convert the main body from the flexible state to the rigid state.

Abstract: A liquid delivery system is configured to pump a liquid (e.g., a cryogenic liquid) without a mechanical pump. The system includes a storage tank to store the liquid at low pressure; a transition tank configured to transition the low pressure liquid to a high pressure gas; and a pumping tank configured to first receive part of the low pressure liquid from the source tank and then to receive the pressurized gas from the transition tank to expel the low pressure liquid from the pumping tank. The liquid delivery system can be used to deliver fuel to an engine (e.g., on an aircraft).

Abstract: Embodiments of the invention provide devices, systems, and methods that precisely identify a minimum of one predetermined spot which is hidden under a skin. The system comprises a locator device and corresponding implanted target device. The port locator device preferably comprises one magnet with north and south magnetic pole, a body and a suspending component. The body may utilize specific geometry which improves accuracy. The implanted target device may include at least one magnet and at least one target or a plurality of targets and at least one magnet. Various configurations can be provided that precisely identify a single spot or a plurality of spots which are hidden under a skin.