Abstract: A method for detecting a type of one of plurality of devices attached to a graphics machine, each device being one of at least a first type and a second type. The method includes detecting at a controller the type of device attached to or to be attached to the machine. The controller is capable of preadjusting the device or machine as a function of the detection. A graphics machine includes a controller, a first device connected to the controller, the first device being categorizable as one of at least a first type and a second type, the controller detecting the type of the first device, and a memory accessible by the controller, the memory storing information regarding the first type and the second type.

Abstract: The disclosure details the implementation of an apparatus, method, and system for a macroeconomic equity investment design and trade system (the Wavefront system). The disclosure teaches a set of quantitative tools to help investors design trades around macro themes. Part of the approach is a linked set of models called Wavefronts, which describe how economic shocks ripple through the economy into company performance, market value and equity returns in the US market. In one embodiment, the modeling may be viewed as having in three parts. The first converts an economic shock into a comprehensive set of shifts in the economy. The second takes those economic shifts and drives them into company fundamentals. The third values those fundamentals based on what the market normally pays.

Abstract: A financial instrument is disclosed that provides spread exposure to volatility in an underlying security within an upper and lower range of prices. This is accomplished by combining a long option for the underlying security at one strike price and a short option for the underlying security at a different strike price, where difference between the two prices creates the spread exposure and the choice of option type for the high and low strikes determines whether the overall spread is short or long. The financial instrument is then priced such that the cost of the instrument prevents any possible negative value total returns at the exercise date of the underlying options. In other words, the option spread creates a lower limit on the possible downside risk in the transaction and the purchase price insures that at inception the financial instrument has no possible negative values. In this way, options market trading can be accomplished without requiring additional collateral, credit or insurance.

Abstract: A motorized apparatus to simultaneously excise, retrieve, temporarily store and transport a sample of material has a hollow clamshell casing with a blended contoured grip for the fingers, a horizontal extension to eliminate slippage when held in a user's hand, and a flange bottom portion from which a removable cutting tool threaded to a drive shaft extends downwards. Within the clamshell casing an electric motor is mounted which drives, via gears, a drive shaft which rotates a cutting tool threaded to the distal end of the drive shaft. The end of the cutting tool, distal from the clamshell casing, forms a cutting edge circumscribing a circular region. An ejection rod slides reciprocally within the cutting tool between a stowed position and an expulsion position.

Abstract: The invention concerns pyridine and pyrazine derivatives of Formula I or a pharmaceutically-acceptable salt thereof, wherein each of W, G1, G2, G3, G4, J, Ring A, n and R3 has any of the meanings defined hereinbefore in the description; processes for their preparation, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use in the treatment of cell proliferative disorders.

Abstract: The disclosure details the implementation of an apparatus, method, and system for a macroeconomic equity investment design and trade system (the Wavefront system). The disclosure teaches a set of quantitative tools to help investors design trades around macro themes. Part of the approach is a linked set of models called Wavefronts, which describe how economic shocks ripple through the economy into company performance, market value and equity returns in the US market. In one embodiment, the modeling may be viewed as having in three parts. The first converts an economic shock into a comprehensive set of shifts in the economy. The second takes those economic shifts and drives them into company fundamentals. The third values those fundamentals based on what the market normally pays.

Abstract: A system and method for triggering an external device in response to an electrocardiogram signal. In one embodiment the method includes determining a peak in the electrocardiogram signal, determining if the electrocardiogram signal is rising or falling at the peak in the signal and triggering a device in response to the rising or falling peak. In one embodiment of the invention an external trigger signal is produced only a rising peak is detected. In one embodiment, the system includes a microprocessor, a peak detector and a trigger circuit. The trigger circuit outputs a trigger signal to an external device when signaled by the peak detector and not inhibited by a signal from the microprocessor.

Abstract: The present invention discloses apparatuses, systems and methods for providing optimal hedge portfolios that minimize single stock idiosyncratic risk for a given level of transactional costs. This is accomplished by deriving hedge portfolios with the maximum effective n for various levels of transaction costs. In one exemplary embodiment the maximum effective n portfolios are derived by starting with a sample portfolio, such as a capital weighted index, and using a hill climbing algorithm to iteratively modify the sample portfolio to map out the optimal effective n portfolios.

Abstract: A quinazoline derivative of the formula I: wherein: R1, R2, R3, R3a, R4, R5, R5a R6, R7, a, m and p are as defined in the description. Also claimed are pharmaceutical compositions containing the quinazoline derivative, the use of the quinazoline derivatives as medicaments and processes for the preparation of the quinazoline derivative. The quinazoline derivatives of formula I, are useful in the treatment of hyperproliferative disorders such as a cancer.

Abstract: A method for detecting a type of one of plurality of devices attached to a graphics machine, each device being one of at least a first type and a second type. The method includes detecting at a controller the type of device attached to or to be attached to the machine. The controller is capable of preadjusting the device or machine as a function of the detection. A graphics machine includes a controller, a first device connected to the controller, the first device being categorizable as one of at least a first type and a second type, the controller detecting the type of the first device, and a memory accessible by the controller, the memory storing information regarding the first type and the second type.

Abstract: A method for detecting a type of one of plurality of devices attached to a graphics machine, each device being one of at least a first type and a second type. The method includes detecting at a controller the type of device attached to or to be attached to the machine. The controller is capable of preadjusting the device or machine as a function of the detection. A graphics machine includes a controller, a first device connected to the controller, the first device being categorizable as one of at least a first type and a second type, the controller detecting the type of the first device, and a memory accessible by the controller, the memory storing information regarding the first type and the second type.

Abstract: The invention concerns pyridine and pyrazine derivatives of Formula I or a pharmaceutically-acceptable salt thereof, wherein each of W, G1, G2, G3, G4, J, Ring A, n and R3 has any of the meanings defined hereinbefore in the description; processes for their preparation, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use in the treatment of cell proliferative disorders.

Abstract: A method for detecting a type of one of plurality of devices attached to a graphics machine, each device being one of at least a first type and a second type. The method includes detecting at a controller the type of device attached to or to be attached to the machine. The controller is capable of preadjusting the device or machine as a function of the detection. A graphics machine includes a controller, a first device connected to the controller, the first device being categorizable as one of at least a first type and a second type, the controller detecting the type of the first device, and a memory accessible by the controller, the memory storing information regarding the first type and the second type.

Abstract: The present invention relates to compounds that inhibit of a5b1 function, processes for their preparation, pharmaceutical compositions containing them as the active ingredient, to their use as medicaments and to their use in the manufacture of medicaments for use in the treatment in warm-blooded animals such as humans of diseases that have a significant angiogenesis or vascular component such as for treatment of solid tumours. The present invention also relates to a5b1 antagonists that also exhibit appropriate selectivity profile(s) against other integrins.

Abstract: Monitoring an electronic check processing status of an image cash letter (“ICL”) and items in the ICL includes processing each ICL item by performing at least one electronic check processing event in connection with the item. For each electronic check processing event and for each item, a record comprising information related to a status of the electronic check processing event is created. Each record is associated with the corresponding item and the ICL. A status of each item can be determined based on the information stored in the records corresponding to that item. A status of the ICL can be determined based on the status of the items from the ICL.

Abstract: Systems and methods for providing encryption and decryption of data transmitted on a computer implemented network, preferably user authentication identifier data, such as a password, at the point of entry into the user's computer. The systems and methods enable an end user to mentally select a marker from one of the randomly arranged elements on a first portion of a graphical image. A second portion of the graphical image includes an arrangement of possible elements of any individual authentication identifier sequence, and is positioned adjacent to the first portion. The systems and methods prompt a user to enter each element of the identifier by moving the selected marker and the first portion as necessary to substantially align the selected marker with a chosen element of the authentication identifier appearing on the outer portion. According to one embodiment, the image portions are concentric wheels. According to another embodiment, the image portions are arranged in adjacent rows.

Abstract: Systems and methods for providing encryption and decryption of data transmitted on a computer implemented network, preferably user authentication identifier data, such as a password, at the point of entry into the user's computer. The systems and methods enable an end user to mentally select a marker from one of the randomly arranged elements on a first portion of a graphical image. A second portion of the graphical image includes an arrangement of possible elements of any individual authentication identifier sequence, and is positioned adjacent to the first portion. The systems and methods prompt a user to enter each element of the identifier by moving the selected marker and the first portion as necessary to substantially align the selected marker with a chosen element of the authentication identifier appearing on the outer portion. According to one embodiment, the image portions are concentric wheels. According to another embodiment, the image portions are arranged in adjacent rows.

Abstract: Balancing image cash letters (“ICLs”) and ICL items during electronic check processing includes determining whether each item has been presented to a receiving institution for payment. A tracking module can track an incoming ICL/item's processing status using records comprising information regarding the ICL/item's status for electronic check processing events. The tracking module can present the ICL/item's processing status in one or more reports. The tracking module can balance an ICL by comparing an incoming ICL value amount with an outgoing ICL value amount. The incoming ICL value amount comprises the total value of the items in the incoming ICL. The outgoing ICL value amount comprises the total value of the items in the incoming ICL that have been presented to a receiving institution via one or more outgoing ICLs. If the amounts match, then the incoming ICL is balanced. If not, then the ICL is not balanced.