Abstract: The invention relates to new quinoxaline derivative compounds of formula (I), to pharmaceutical compositions comprising said compounds, to processes for the preparation of said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.

Abstract: A method and apparatus for communicating system information in a wireless communication system is provided. The method comprises generating and sending by a base station, for example an eNB, a system information block (SIB) which includes at least one correlation enhancement bit. This SIB is received by the terminal, for example a MTC UE, and this SIB is subsequently correlated with a previously received SIB. Further, upon the correlation of the SIB and the previously received SIB, a determination is made whether the SIB has in fact changed. Upon determining if the SIB has changed, the terminal selects the correct SIB which is to be used for configuring communication with the base station.

Abstract: A disclosed system, method and computer readable storage medium includes mechanism for controlling cascade price movements in an electronic trading system. Price limits control the prices at which traders can place orders. An upper price limit prevents traders from placing orders above the upper limit and a lower price limit prevents traders from placing orders below the lower limit. The gap between the upper limit and the indicative marked price as well as the gap between lower limit and the indicative market price is controlled so as to cause a breaking effect on very rapidly changing market price.

Abstract: The invention relates to new quinoline derivative compounds of formula (I), to pharmaceutical compositions comprising said compounds, to processes for the preparation of said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.

Abstract: A method of operating a transfer printer (1), the transfer printer comprising first and second spool supports each being configured to support a spool (3,4) of ribbon (2), a ribbon drive configured to cause movement of ribbon (2) from the first spool support to the second spool support along a predetermined ribbon path, and a printhead (7), the printhead being configured to selectively transfer ink from the ribbon to a substrate as the substrate is moved relative to the printhead in a direction of substrate movement. The method comprises driving the ribbon in a direction parallel to the direction of substrate movement, printing a first plurality of images onto a first respective plurality of substrates, driving the ribbon in a direction opposite to the direction of substrate movement, driving the ribbon in the direction parallel to the direction of substrate movement, and printing a second plurality of images onto a second respective plurality of substrates.

Abstract: This application concerns an apparatus comprising a housing arranged to be positioned at any one of a plurality of rotational angles, a display mounted to the housing and a processor arranged to execute instructions stored in a memory. The instructions are arranged to cause a user interface to be displayed on the display, to receive an indication of a rotation amount and rotation direction from a rotation input, rotate at least one corner element about its centre point by the rotation amount in the rotation direction and if the rotation amount is greater than a first predetermined limit, move the at least one corner element to a different one of a plurality of corner portions of the display.

Abstract: The present invention pertains generally to the field of chemical synthesis, and more particularly to methods of chemical synthesis which include the step of preparing a substituted 10H-phenothiazine-3,7-diamine compound of Formula (1) by a step of selective alkylation by reductive amination, in which the corresponding unsubstituted diamine of Formula (4) is reacted with aldehyde/ketone, under reductive amination conditions. The present invention also relates to such methods which incorporate additional subsequent and/or preceding steps, for example, to prepare compounds of Formulae (2) and (3) from compounds of Formula (1), and to prepare compounds of Formula (4) from, for example, compounds of Formulae (5), (6), (7), (8), and (9). Compounds of Formula (1), Formula (2), and Formula (3) are useful, for example, in the treatment of diseases of protein aggregation, such as Alzheimer's disease.

Abstract: A remote attestation system for a computer network includes an attestation operations subsystem configured to manage attestation procedures for the remote attestation system, and an attestation server pool including a plurality of attestation servers. The plurality of attestation servers is configured to perform attestation of at least one host in a data center. The system further includes an attestation state database configured to store a state of attestation of the at least one host, an attestation policy database configured to store at least one operator policy of the computer network, and an end-user service portal configured to provide access to the remote attestation system by users of the computer network.

Abstract: Certain exemplary embodiments can provide a method comprising automatically rendering a message to a webpage user, the message created by a webpage operator via an automatic merger of a customized message content that corresponds to a message-generator-selected message identifier with a message template that corresponds to a message-generator-selected message template identifier, the message-generator-selected message identifier and the message-generator-selected message template identifier provided by the message generator to the webpage operator responsive to receipt of data gathered from the webpage user by the webpage operator.

Abstract: Disclosed are devices, methods and systems for treatment of eye disease such as glaucoma. Implants are described herein that enhance aqueous flow through the normal outflow system of the eye with minimal to no complications. The implant can be reversibly deformed to a first shape, such as a generally linear shape conducive to insertion. Upon insertion, the implant can deform to a second shape, such as a generally non-linear shape conducive to retention within the eye. The shape also improves fluid flow from the anterior chamber and prevents or reduces clogging.

Abstract: A wearable image display system includes a headpiece, a first and a second light engine, and a first and a second optical component. The first and second light engines generate a first and a second set of beams respectively, each beam substantially collimated so that the first and second set form a first and a second virtual image respectively. Each optical component is located to project an image onto a first and a second eye of a wearer respectively. The first and second sets of beams are directed to incoupling structures of the first and second optical components respectively. Exit structures of the first and second optical components guide the first and second sets of beams onto the first and second eyes respectively. The optical components are located between the light engines and the eyes. Both of the light engines are mounted to a central portion of the headpiece.

Abstract: A system and a method for controlling a vehicle with a joystick that includes implementing at least one dead band for the joystick. The dead band prevents movement of the vehicle when the joystick is within the dead band areas. The dead band areas are adjustable and take a plurality of shapes including having gaps between areas of the dead band areas. These dead bands allow for smooth operation of a vehicle by suppressing the control signal of the joystick for unintentional movements of the joystick by the operator. The adjustability of the dead band allows for adjustment based on the joystick type, the vehicle type, and the control desired.

Abstract: Apparatuses and systems for rotatably engaging an additive manufacturing build plate are disclosed. An apparatus may include: a height adjustable platform; a rotatable member coupled to the height adjustable platform; an alignment member coupled to a first end of the rotatable member; and first and second coupling members each extending from the first radial end of the alignment member wherein the first and second coupling members are oriented substantially parallel to the rotatable member.

Abstract: A process variable transmitter for use in an industrial process includes a housing having a cavity formed therein. The housing has a barrier which divides the cavity into first and second cavities. Preferably, measurement circuitry in the first cavity is configured to measure a process variable of the industrial process. A terminal block assembly is positioned in the second cavity. The terminal block assembly forms a seal with the housing thereby forming a third cavity between the barrier and a circuit board of the terminal block assembly.

Abstract: The invention relates to an efficient polymerization process and its use to produce novel copolymers with a specific micro structure. In particular, the invention relates to butyl rubbers with novel micro structure, preferably those obtainable by copolymerization of monomer mixtures comprising isobutylene and isoprene in diluents comprising 2,3,3,3 -tetrafluoro-1-propene. In a further aspect the invention relates to halogenated copolymers obtainable from such novel copolymers by halogenation.

Abstract: A bucket level indicator mechanism for use with work machine with a front mounted loader implement includes a carriage assembly having a carriage frame comprising a carriage back and first and second carriage endplates at longitudinal ends of the carriage back, a first end of the carriage assembly being pivotably connected to one of the masts, wherein the carriage back has a slot formed therein along a portion of its longitudinal length. At least one guide rod extends between the carriage endplates. A boom height compensating link is mounted on the upper arm section. The boom height compensating link has at least one fixed traveler configured to be received in the slot in the carriage back, the carriage assembly being mounted so as to slide relative the traveler, wherein as the loader boom is raised and lowered by extension or retraction of the lift actuator, the carriage assembly rotates relative the mast about a pivot as the traveler slides in the slot in the carriage back.

Abstract: A MEMS laser scanner is disclosed for use in a near-eye display including an increased field of view (FOV). In embodiments, one or more polarization gratings may be applied to the mirror of the MEMS laser scanner, which polarization gratings may be configured according to the Bragg regime. Using light of different polarizations, the MEMS laser scanner is able to expand the FOV without increasing the range over which the mirror of the scanner oscillates.

Abstract: A tile-based graphics system has a rendering space sub-divided into a plurality of tiles which are to be processed. Graphics data items, such as parameters or texels, are fetched into a cache for use in processing one of the tiles. Indicators are determined for the graphics data items, whereby the indicator for a graphics data item indicates the number of tiles with which that graphics data item is associated. The graphics data items are evicted from the cache in accordance with the indicators of the graphics data items. For example, the indicator for a graphics data item may be a count of the number of tiles with which that graphics data item is associated, whereby the graphics data item(s) with the lowest count(s) is (are) evicted from the cache.

Abstract: A histogramming readout circuit is described. The readout circuit comprises a time to digital converter (TDC) configured to continually report time-stamps defining an arrival time of a laser clock and a signal output from a photosensor. Memory is provided for storing TDC events. A programmable processor is configured to implement a state machine. The state machine being operable to saves a time-stamp when a TDC event is detected; determine the time of flight of each of the photons detected by the photosensor; using each calculated time of flight to address a memory location; building up a histogram of the TDC data values using the memory locations as time-bins; maintaining a pointer to a maximum memory location where the highest number of TDC event resides. A calculator is operable to read the value of the maximum memory location and one or more adjacent time-bins either side for processing.

Abstract: An automation control system is provided that includes a distributed automation component that receives and processes delta scripts describing state changes to one or more objects of a persistent object model.