Abstract: A head unit system for controlling motion of an object includes a secondary object sensor, shear thickening fluid (STF), and a chamber configured to contain a portion of the STF. The chamber further includes a front channel and a back channel. The head unit system further includes a piston housed at least partially radially within the piston compartment and separating the back channel and the front channel. The piston includes a first piston bypass and a second piston bypasses to control flow of the STF between opposite sides of the piston. The chamber further includes a set of fluid manipulation emitters to control the flow of the STF to cause selection of one of a variety of shear rates for the STF within the chamber.

Abstract: The invention provides a compound of formula (1). or tautomer or a solvate or a pharmaceutically acceptable salt thereof, wherein the various substituents are as defined in the claims. Also provided are pharmaceutical compositions containing the compounds of formula (I), processes for making the compounds and the medical uses of the compounds.

Abstract: Devices, systems, and methods are provided for registering image data with robotic data for image-guided robotic catheters and other elongate bodies. Fluid drive systems can be used to provide robotically coordinated motion. Precise control over catheter-supported tools is enhanced by alignment of fluoroscopic and ultrasound image data, particularly for structural heart and other therapies in which the catheter will interact with soft tissues. A marker plate having a planar array of machine-readable 2D barcode markers may facilitate alignment of image and robotic data. Determining an ultrasound-based pose of a component in the ultrasound image field allows that component to effectively a fiducial for alignment.

Abstract: Provided are electrode assemblies that include framed electrodes comprising a conductive fabric having an edge sealed by an infiltrated sealant, the sealed portion of the fabric being sealed to a frame. Also provided are electrochemical cell stacks that include electrode assemblies according to the present disclosure.

Abstract: One example includes a vapor cell. The cell includes a transparent enclosure and alkali metal atoms enclosed within the transparent enclosure. The alkali metal atoms can be configured to be stimulated from a first energy state to a second energy state in response to an optical beam provided through the vapor cell and to emit fluorescent light in response to energy of the alkali metal atoms decaying from the second energy state to the first energy state. The cell further includes a reflective coating that is provided on an exterior surface of the transparent enclosure to surround the vapor cell to provide a reflective interior surface with respect to the transparent enclosure of the vapor cell to reflect the fluorescent light. The reflective coating can include a detection window configured to facilitate escape of the fluorescent light from the vapor cell for optical detection.

Abstract: A text mining engine running on an artificial platform is trained to perform conversation role identification, semantic analysis, summarization, language detection, etc. The text mining engine analyzes words in a transcript that represent unique characteristics of a conversation and, based on the unique characteristics and utilizing classification predictive modeling, determines a conversation role for each participant of the conversation and metadata describing the conversation such as tonality of words spoken by a participant in a particular conversation role. Outputs from the text mining engine are indexed and useful for various purposes. For instance, because the system can identify which speaker in a customer service call is likely an agent and which speaker is likely a customer, words spoken by the agent can be analyzed for compliance reasons, training agents, providing quality assurance for improving customer service, providing feedback to improve the performance of the text mining engine, etc.

Abstract: Compounds, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.

Abstract: The present invention relates to methods for the detection of nucleic acids of defined sequence and kits and devices for use in said methods. The methods employ restriction enzymes, polymerase and oligonucleotide primers to produce an amplification product in the presence of a target nucleic acid, which is contacted with oligonucleotide probes to produce a detector product.

Abstract: The invention relates to processes for preparing isoindolin-1-one derivatives, and in particular processes for preparing (2S,3S)-3-(4-chlorophenyl)-3-[(1R)-1-(4-chlorophenyl)-7-fluoro-5-[(1S)-1-hydroxy-1-(oxan-4-yl)propyl]-1-methoxy-3-oxo-2,3-dihydro-1H-isoindol-2-yl]-2-methylpropanoic acid. The invention also relates to crystalline forms of the compound (2S,3S)-3-(4-chlorophenyl)-3-[(1R)-1-(4-chlorophenyl)-7-fluoro-5-[(1S)-1-hydroxy-1-(oxan-4-yl)propyl]-1-methoxy-3-oxo-2,3-dihydro-1H-isoindol-2-yl]-2-methylpropanoic acid and its salts.

Abstract: A telecommunications system is disclosed that coordinates and executes complex communication tasks using structured messaging and off-line synchronization.

Abstract: This disclosure relates to orthopaedic implants and methods for restoring functionality to a joint. The implants described herein may be utilized during orthopaedic procedures and may be incorporated into a shoulder prosthesis for restoring functionality to shoulders having advanced cartilage disease. The disclosed implants may incorporate one or more fasteners formed together with a main body of the respective implant at a breakable connection. The fastener may be deployed during a surgical procedure, which may improve fixation of the implant at the surgical site.

Abstract: In one embodiment, a method includes initializing latent codes respectively associated with times associated with frames in a training video of a scene captured by a camera. For each of the frames, a system (1) generates rendered pixel values for a set of pixels in the frame by querying NeRF using the latent code associated with the frame, a camera viewpoint associated with the frame, and ray directions associated with the set of pixels, and (2) updates the latent code associated with the frame and the NeRF based on comparisons between the rendered pixel values and original pixel values for the set of pixels. Once trained, the system renders output frames for an output video of the scene, wherein each output frame is rendered by querying the updated NeRF using one of the updated latent codes corresponding to a desired time associated with the output frame.

Abstract: An example apparatus includes message generator circuitry to generate a first message for a first server of a first Internet domain in response to detecting a login event at a client device, the login event associated with an Internet-based service of a second Internet domain, the second Internet domain outside the first Internet domain, and a communication interface to receive a second message from the first server, the second message including a global unique identifier (GUID) and a login timestamp, the GUID identifying at least one of the client device or a user of the client device to the first Internet domain, the message generator circuitry to generate a third message including (a) the GUID, (b) a cookie identifier associated with the second Internet domain, and (c) the login timestamp, the third message to cause generation of an identifier-to-cookie map at a second server of the second Internet domain.

Abstract: Implantable devices for fixation of curved bone such as the pelvic ring pubic symphysis and acetabulum, and methods for the use of the devices are disclosed. The implantable devices are convertible between a flexible state and a rigid state, and include an elongate structure having a proximal bone interface, a main body, and a distal bone interface. In a flexible state, the devices may be inserted along, and conform to a curved pathway, and in the rigid state, the devices may support the mechanical loads required to fixate a fracture.

Abstract: Gas sensors having laser-induced graphene (LIG) and/or LIG composites, and methods of making and using gas sensors having LIG and/or LIG composites.

Abstract: A method for managing electromagnetic interference (EMI) includes: obtaining a request; in response to the request: terminating EMI generation by EMI emitting devices in an EMI suppressed internal volume of a data processing device to place the EMI emitting devices in a quiet state; placing the EMI suppressed internal volume into an EMI suppression compromised state to obtain access to the EMI emitting devices in the quiet state; replacing one of the EMI emitting devices in the quiet state, to obtain updated EMI emitting devices, while: the EMI suppressed internal volume is in the EMI suppression compromised state, and the EMI emitting devices are in the quiet state; placing the EMI suppressed internal volume into an EMI suppressed state after replacing the one of the EMI emitting devices; and enabling EMI generation by the updated EMI emitting devices to place the updated EMI emitting devices into an active state.

Abstract: Delivery catheter systems and methods for delivery of hypertension treatment implants are provided. Such catheter devices facilitate delivery and placement of an implant in a target region of an aortic arch of the patient to induce baroreflex. Typically, the catheter includes a catheter shaft, and outer sheath constraining an implant with one or more expandable structures in a collapsed configuration, the sheath being retractable to deploy the implant. The catheter can include markers for precise placement and deployment of the implant along the target region. The catheter can include a retention collar that releasably couples with one or more connectors at proximal ends of one or more tethers extending proximally from the implant to allow precise placement at the target region and/or repositioning or removal of the implant. The target region includes a cylindrical segment of aortic arch between the left common carotid artery and the left subclavian artery.

Abstract: Aspects relate to tracing rays in 3-D scenes that comprise objects that are defined by or with implicit geometry. In an example, a trapping element defines a portion of 3-D space in which implicit geometry exist. When a ray is found to intersect a trapping element, a trapping element procedure is executed. The trapping element procedure may comprise marching a ray through a 3-D volume and evaluating a function that defines the implicit geometry for each current 3-D position of the ray. An intersection detected with the implicit geometry may be found concurrently with intersections for the same ray with explicitly-defined geometry, and data describing these intersections may be stored with the ray and resolved.

Abstract: Aspects include a multistage collector to receive outputs from plural processing elements. Processing elements may comprise (each or collectively) a plurality of clusters, with one or more ALUs that may perform SIMD operations on a data vector and produce outputs according to the instruction stream being used to configure the ALU(s). The multistage collector includes substituent components each with at least one input queue, a memory, a packing unit, and an output queue; these components can be sized to process groups of input elements of a given size, and can have multiple input queues and a single output queue. Some components couple to receive outputs from the ALUs and others receive outputs from other components. Ultimately, the multistage collector can output groupings of input elements. Each grouping of elements (e.g., at input queues, or stored in the memories of component) can be formed based on matching of index elements.

Abstract: A method of controlling a viscosity of fuel in a fuel control system with a vibratory meter is provided. The method includes providing the fuel to the vibratory meter, measuring a property of the fuel with the vibratory meter, and generating a signal based on the measured property of the fuel. The method also includes providing the signal to a temperature control unit configured to control the temperature of the fuel provided to the vibratory meter.