Abstract: Micromorphologically crack-free vitreous carbon articles having a length and width each of which is at least 10 mm, and a thickness of at least 5 mm are described, as well as multilayer laminates of micromorphologically crack-free vitreous carbon, and corresponding methods and apparatus for manufacture of same. 3D printed vitreous carbon articles are also described, together with 3D printing apparatus and methods for producing same. Methods are also described for forming vitreous carbon containing vitreous carbon nanolattice articles therein as filler. The vitreous carbon compositions, articles, and laminates of the disclosure overcome the thickness limitations of conventional vitreous carbon manufacturing methods and the microcracking issues attendant previous efforts to produce vitreous carbon of substantial size and thickness.

Abstract: Aspects relate to tracing rays in 3-D scenes that comprise objects that are defined by or with implicit geometry. In an example, a trapping element defines a portion of 3-D space in which implicit geometry exist. When a ray is found to intersect a trapping element, a trapping element procedure is executed. The trapping element procedure may comprise marching a ray through a 3-D volume and evaluating a function that defines the implicit geometry for each current 3-D position of the ray. An intersection detected with the implicit geometry may be found concurrently with intersections for the same ray with explicitly-defined geometry, and data describing these intersections may be stored with the ray and resolved.

Abstract: The present disclosure relates to the treatment of Parkinson's disease. The present disclosure provides, in some embodiments, methods of treating Parkinson's disease in a patient in need thereof. In some embodiments, the methods disclosed herein comprise administering a levodopa therapy based on a patient's biomarker profile. In some embodiments, the levodopa therapy comprises or lacks a tyrosine decarboxylase inhibitor. Therapeutic uses and compositions are also disclosed.

Abstract: A method for depth sensing from an image of a projected pattern is performed at an electronic device with one or more processors and memory. The method includes receiving an image of a projection of an illumination pattern; for a portion of the image, selecting a candidate image of a plurality of candidate images by comparing the portion of the image with a plurality of candidate images; and determining a depth for the portion of the image based on depth information associated with the selected candidate image. Related electronic devices and computer readable storage medium are also disclosed.

Abstract: In one embodiment, a method includes accessing a calibration model for a camera rig. The method includes accessing multiple observations of an environment captured by the camera rig from multiple poses in the environment. The method includes generating an environmental model including geometry of the environment based on at least the observations, the poses, and the calibration model. The method includes determining, for one or more of the poses, one or more predicted observations of the environment based on the environmental model and the poses. The method includes comparing the predicted observations to the observations corresponding to the poses from which the predicted observations were determined. The method includes revising the calibration model based on the comparison. The method includes revising the environmental model based on at least a set of observations of the environment and the revised calibration model.

Abstract: A patient interface for delivering breathable gas to a patient includes a nasal prong assembly including a pair of nasal prongs structured to sealingly communicate with nasal passages of a patient's nose in use and headgear to maintain the nasal prong assembly in a desired position on the patient's face. The headgear includes side straps and rigidizers provided to respective side straps. Each rigidizer includes a first end portion that provides a connector structured to engage a respective end of the nasal prong assembly and an inwardly curved protrusion in the form of a cheek support that curves inwardly of the connector. The cheek support is adapted to follow the contour of the patient's cheek and guide a respective end portion of the side strap into engagement with the patient's cheek to provide a stable cheek support.

Abstract: A method includes generating, via a processor, a bill of materials (BOM) representation associated with a BOM indicating at least one good and including a representation of a plurality of dependencies to qualify the at least one good for at least one of a regulatory claim, a duty benefit claim or an admissibility claim. A smart contract code for a compliance declaration smart contrast that references the BOM representation is transmitted via the processor and to a distributed ledger. A representation of the plurality of assertion token is received, via the processor, from a plurality of remote compute devices, and in response to deploying the compliance declaration smart contract. A compliance declaration token is minted, via the processor, in response to receiving the representation of a plurality of assertion tokens and based on the compliance declaration smart contract.

Abstract: Various embodiments of the present technology may provide methods and apparatus for repetitive histogramming. The apparatus may provide a limited number of physical bins to perform multiple histograms on a total number of virtual bins. The apparatus may provide a single physical bin that is used to sweep over the total number of virtual bins.

Abstract: A patient interface for delivering breathable gas to a patient includes a nasal prong assembly including a pair of nasal prongs structured to sealingly communicate with nasal passages of a patient's nose in use and headgear to maintain the nasal prong assembly in a desired position on the patient's face. The headgear includes side straps and rigidizers provided to respective side straps. Each rigidizer includes a first end portion that provides a connector structured to engage a respective end of the nasal prong assembly and an inwardly curved protrusion in the form of a cheek support that curves inwardly of the connector. The cheek support is adapted to follow the contour of the patient's cheek and guide a respective end portion of the side strap into engagement with the patient's cheek to provide a stable cheek support.

Abstract: A brake pedal assembly comprising a pedal and a pedal resistance force member operably coupled to the pedal. A damper pedal resistance force module defines an interior fluid-filled cavity. A shaft extends through the damper module and includes a piston mounted thereon and moveable through the fluid-filled cavity to generate a damper resistance force. A spring pedal resistance force module is adapted to generate a spring pedal resistance force. A pedal force sensing module is mounted to the pedal resistance force member. A pedal position sensor is mounted to the pedal resistance force member. A pedal force sensor is mounted to the pedal resistance force member.

Abstract: A blower unit for use as part of an integrated blower/humidification system is described. The blower unit has an outer casing, which encloses and forms part of the blower unit, the casing including an air inlet vent. The blower unit further includes a humidifier compartment for receiving a humidifier unit with a separate gases inlet and outlet, the compartment having a heater base for heating the contents of the humidifier unit. The compartment also has a blower inlet port which aligns with the humidifier unit inlet in use, the blower providing a gases path through the casing between the inlet vent and the inlet port. The blower unit also includes a fan for providing a pressurised gases stream along the gases path, and a power supply unit for powering the fan. The gases path is routed over the power supply unit in order to provide a cooling air flow.

Abstract: An apparatus for automated mold polishing is disclosed. In an embodiment, the apparatus comprises at least a processor and a memory communicatively connected to the processor. The memory containing instructions configuring the at least a processor to receive a finish assignment for at least a surface of a part for manufacture. The processor then determines a polish strategy for the at least a surface as a function of a geometry of the at least a surface. A polishing tool may then be selected for the at least a surface as a function of the finish assignment and the polish strategy for the at least a surface. A reachable area is then determined of the at least a surface as a function of the polishing tool. The processor then generates a toolpath as a function of the reachable area.

Abstract: The present invention relates to the treatment of or alleviation of signs and symptoms of palmoplantar pustulosis (PPP) with anti-IL-36R antibodies in a patient.

Abstract: A breathing arrangement includes a patient interface, at least one inlet conduit, and a headgear assembly. The patient interface includes a mouth covering assembly including a cushion structured to sealingly engage around exterior of a patient's mouth in use, a nozzle assembly including a pair of nozzles structured to sealingly engage within nasal passages of a patient's nose in use, and a flexible element connecting the mouth covering assembly and the nozzle assembly. The at least one inlet conduit is structured to deliver breathable gas into at least one of the mouth covering assembly and the nozzle assembly for breathing by the patient. The headgear assembly is removably connected to at least one of the mouth covering assembly and the nozzle assembly so as to maintain the mouth covering assembly and the nozzle assembly in a desired position on the patient's face.

Abstract: A tape support arrangement comprises a tape take up core (220) suitable for supporting a tape; and a tape supply core (210) suitable for supporting a tape (230). The supply core (210) comprises an inner surface (212), the inner surface defining an internal volume (240) of the supply core and being configured for engagement with a tape drive support. The take up core (220) is sized and shaped such that it can be located in the internal volume (240) of the supply core (210). Refer to FIG. 2.

Abstract: In one embodiment, a computing system instructs, at a first time, a camera having a plurality of pixel sensors to use the plurality of pixel sensors to capture a first image of an environment comprising an object. The computing system predicts, using at least the first image, a projection of the object appearing in a virtual image plane associated with a predicted camera pose at a second time. The computing system determines, based on the predicted projection of the object, a first region of pixels and a second region of pixels. The computing system generates pixel-activation instructions for the first region of pixels and the second region of pixels. The computing system instructs the camera to capture a second image of the environment at the second time according to the pixel-activation instructions.

Abstract: The present invention relates to the treatment of or alleviation of signs and symptoms of palmoplantar pustulosis (PPP) with anti-IL-36R antibodies in a patient.

Abstract: In one embodiment, a method includes accessing a digital image captured by a camera that is connected to a machine-detectable object, detecting a reflection of the machine-detectable object in the digital image, computing, in response to the detection, a plane that is coincident with a reflective surface associated with the reflection, determining a boundary of the reflective surface in the plane based on at least one of a plurality of cues, and storing information associated with the reflective surface, where the information includes a pose of the reflective surface and the boundary of the reflective surface in a 3D model of a physical environment, and where the information associated with the reflective surface and the 3D model are configured to be used to render a reconstruction of the physical environment.

Abstract: A computing device is provided, including a processor configured to execute an application-under-test including a plurality of tasks. Each task may be executed in one or more task instances. The processor may determine respective performance data for the one or more task instances of each task. The processor may output, for display on a display, a graphical user interface (GUI) including a statistical representation of the performance data. The processor may receive, at the GUI, a selection of a task executed in a plurality of selected task instances in the application-under-test. The selected task instances may be executed in selected task execution time intervals that are at least partially non-contiguous in time. The processor may generate an aggregated view of the corresponding performance data for the selected task instances aggregated over the selected task execution time intervals. The processor may output the aggregated view for display at the GUI.

Abstract: Methods for snapshot isolation query transactions in distributed systems are performed by systems and devices. Distributed executions of queries are performed in a processing system according to an isolation level protocol for data management and data versioning across one or more data sets, one or more compute pools, etc., within a logical server via a single transaction manager that oversees the isolation semantics and data versioning. Read transactions of queries are performed lock-free via the isolation semantics, and instant rollbacks, point-in-time queries, single-phase commits in the distributed systems are also provided. Abort and cleanup operations are performed based on a distributed abort protocol and a determined oldest active transaction for the system in which the single transaction manager does not track read-only transactions, and client nodes do not maintain commit tables for transactions.