Abstract: Devices for restricting flow in blood vessels, and methods of using said devices, the device comprising a first end; a second end; a first opening positioned at the first end, a size of the first opening adjustable from a first size to a second size; a second opening positioned at the second end, the second opening having a greater cross-sectional area than the first opening; and a plurality of struts extending from the first end toward the second end and defining the first opening and the second opening, the plurality of struts extending in a radially outward direction along a portion of their length, wherein the device is collapsible to enable percutaneous delivery.

Abstract: A blower unit for use as part of an integrated blower/humidification system is described. The blower unit has an outer casing, which encloses and forms part of the blower unit, the casing including an air inlet vent. The blower unit further includes a humidifier compartment for receiving a humidifier unit with a separate gases inlet and outlet, the compartment having a heater base for heating the contents of the humidifier unit. The compartment also has a blower inlet port which aligns with the humidifier unit inlet in use, the blower providing a gases path through the casing between the inlet vent and the inlet port. The blower unit also includes a fan for providing a pressurised gases stream along the gases path, and a power supply unit for powering the fan. The gases path is routed over the power supply unit in order to provide a cooling air flow.

Abstract: Compounds, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.

Abstract: Disclosed herein are active agents, compositions containing them, unit dosage forms containing them, and methods of their use, e.g., for treating a metabolic disorder or nonalcoholic fatty liver disease or for modulating a metabolic marker or nonalcoholic fatty liver disease marker.

Abstract: A multi-spectral optical imaging device includes a switchable element configured to be switched between first and second states, one of which alters a polarization of light, and a geometric phase element arranged to receive the light from the switchable element. The geometric phase element is configured to diffract a first wavelength band of the light to alter a direction of propagation thereof based on the polarization and without substantially altering a direction of propagation of a second wavelength band of the light, responsive to the first state of the switchable element. Related optical shutters and multi-spectral optical detectors are also discussed.

Abstract: Disclosed are conjugates including a recognition element covalently bonded to or linked through a linker to a payload. The payload is a pharmaceutical agent (e.g., an antineoplastic agent, anti-infective agent, or anti-inflammatory agent) or a diagnostic agent. Also disclosed are methods of using the conjugates.

Abstract: Disclosed are 2,8-diazaspiro[4.5]decane compounds, including (pyrido[3,4-d]pyrimidin-4-yl)-2,8-diazaspiro[4.5]decane compounds, (2,6-naphthyridin-1-yl)-2,8-diazaspiro[4.5]decane compounds, and (1,7-naphthyridin-4-yl)-2,8-diazaspiro[4.5]decane compounds, that are inhibitors of LATS1/2, compositions containing these compounds, and methods for inhibiting LATS1/2 activity.

Abstract: An aspect of the present disclosure is a method that includes depositing an ink as a liquid strand onto a substrate, transforming the liquid strand to a precursor strand, converting at least a portion of the precursor strand to a nanowire that includes a first metal, and coating the nanowire with a second metal to form a core-shell nanowire having a core and a shell, where at least a portion of the transforming occurs during the depositing, and the core includes the nanowire and the shell includes the second metal.

Abstract: In a system and method for processing computer system events asynchronously for software security operations, a computer memory is configured for a read operation by a computer process. The computer process loads, based on a first event occurring during the read operation, at least one file in the computer memory. At least one thread of the computer process is generated. An execution of the at least one thread of the computer process is delayed based on a second event occurring after the first event. A security operation is performed on the process contemporaneously with the loading of the file in the computer memory and the blocking of the execution of the at least one thread of the computer process. The process is either un-delayed on completion of the previous security operation or other security operations performed on that process.

Abstract: An association management system for establishing, maintaining, and monitoring associations between a personal identifier and an electronic device, includes a provider subsystem in operable communication with at least one of the personal identifier and the electronic device. The provider subsystem is configured to provision a person associated with the personal identifier, authenticate both of the personal identifier and the electronic device, and establish an association of the authenticated personal identifier to the authenticated electronic device. The system further includes a certificate authority subsystem for issuing at least one digital certificate to verify an identity of one or more digital entities operating on the management system, and a digital distributed ledger including a plurality of a consensus pool of participating processors. The digital distributed ledger is configured to verify, using the at least one digital certificate, transaction events of the association management system.

Abstract: A method for detecting malicious activity of a computing device comprises detecting, by a software driver executing within a kernel mode of an operating system being executed by the computing device, an operation performed at the computing device; intercepting the operation; receiving, by a security application executing within a user mode of the operating system, a request from the software driver for an instruction for the software driver for an action to block or allow the operation according to a first timeout value; generating a second timeout value based on an amount of time determined by the security application; transmitting a reply to the request that includes the second timeout value to the software driver; transmitting the instruction to the software driver in compliance with the second timeout value; and executing, by the software driver, the action in response to the instruction.

Abstract: Various embodiments of the present technology may provide methods and apparatus for region of interest histogramming. The apparatus may use a state machine in conjunction with a memory to generate a first histogram having a fixed number of bins over a first range and generate a second histogram having the fixed number of bins over a region of interest selected based on the first peak of the first histogram.

Abstract: A method for producing seed corn from the corn plants, for use in growing subsequent corn plants, includes measuring a moisture content of corn kernels on ears of the corn plants in the field and removing, by a combine harvester, the ears of corn from the corn plants when the moisture content satisfies a threshold moisture content. The method then includes separating the corn kernels from cobs of the ears of corn onboard the combine harvester and collecting the separated corn kernels for use as seed corn, whereby one or more subsequent corn plants can be grown from the collected corn kernels.

Abstract: Embodiments as disclosed provide data processing systems and methods for controlling an automated survey system. One embodiment comprises: a processor; a data store storing a plurality of transactions thereon, each transaction comprising transaction metadata and a voice session recording of an inbound call, the transaction metadata for each transaction comprising an identifier for that transaction; a non-transitory computer readable medium having instructions executable on the processor for: generating, by the processor, a worklist for the survey campaign to control conducting of surveys by an automated survey system that is configured to execute the worklist, the worklist comprising a work item for each of the set of transactions and each work item comprising transaction identification data for a transaction from the set of transactions and contact information for the survey target for the transaction corresponding to the transaction identification data in the work item.

Abstract: The disclosure herein describes systems and methods for object data storage. In some examples, the method includes generating a profile for an object in a directory, the profile including a first feature vector corresponding to the object and a global unique identifier (GUID) corresponding to the first feature vector in the profile; generating a search scope, the search scope including at least the GUID corresponding to the profile; generating a second feature vector from a live image scan; matching the generated second feature vector from the live image scan to the first feature vector using the generated search scope; identifying the GUID corresponding to the first feature vector that matches the second feature vector; and outputting information corresponding to the object of the profile identified by the GUID corresponding to the first feature vector.

Abstract: The present invention relates to a multipurpose drill system, the multipurpose drill system comprising: a drilling rig adapted to drive a drilling assembly; and two or more power sources, wherein at least one of the two or more power sources is a high pressure power source, wherein the drilling assembly is adapted to be in communication with either or both of the two or more power sources.

Abstract: A virtualized blockchain forest includes a plurality of individual blockchains. Each individual blockchain of the plurality includes a blockchain height, a genesis block, and at least one additional block. The virtualized blockchain forest further includes a plurality of participating processors that make up a consensus pool, and a blockchain forest height having a time-sequenced start-to-finish length of blocks among the collective plurality of individual blockchains. The virtualized blockchain forest is configured to aggregate different ones of the plurality of individual blockchains, and is further configured to terminate individual ones of plurality of individual blockchains.

Abstract: Embodiments as disclosed provide data processing systems and methods for controlling an automated survey system. One embodiment comprises: a processor; a data store storing a plurality of transactions thereon, each transaction comprising transaction metadata and a voice session recording of an inbound call, the transaction metadata for each transaction comprising an identifier for that transaction; a non-transitory computer readable medium having instructions executable on the processor for: generating, by the processor, a worklist for the survey campaign to control conducting of surveys by an automated survey system that is configured to execute the worklist, the worklist comprising a work item for each of the set of transactions and each work item comprising transaction identification data for a transaction from the set of transactions and contact information for the survey target for the transaction corresponding to the transaction identification data in the work item.

Abstract: Selective discharging of a rechargeable battery pack across a power supply system load is provided, which includes determining occurrence of a condition within the power supply system, the power supply system including a power supply circuit and a backup energy source. The power supply circuit receives main input power, and the backup energy source is operatively coupled to the power supply circuit to supply backup power to the system load when main power input to the power supply circuit is unavailable. Based on determining occurrence of the condition within the power supply system, a controller actively discharges a rechargeable battery pack of the backup energy source. The actively discharging includes controlling the power supply circuit to force discharging of power from the rechargeable battery pack to the power supply system load by suspending the main input power within the system from powering the system load.

Abstract: A method of estimating a temperature of a component of a wind turbine is provided, comprising, during a calibration period, receiving measurements of the temperature of the component and of one or more corresponding operational parameter; and calculating, using the measurements coefficients of a model of the temperature of the component. The model relates temperature at a current time to a temperature a preceding time, Tn?1. The model is segregated into separate bins based on wind speed or power generated by the wind turbine. The method further comprises using the model to estimate a temperature of the wind turbine.