Abstract: Aminosterol compounds are described that are useful as inhibitors of the sodium/proton exchanger (NHE). Methods of using such aminosterols compounds are also enclosed, including those employing compounds that are inhibitors of a spectrum of NHEs as well as those using compounds that are inhibitors of only one specific NHE. Advantageous screening techniques and assays for evaluating a compound's therapeutic activity are also disclosed.

Abstract: Aminosterol compounds are described that are useful as inhibitors of the sodium/proton exchanger (NHE). Methods of using such aminosterols compounds are also enclosed, including those employing compounds that are inhibitors of a spectrum of NHEs as well as those using compounds that are inhibitors of only one specific NHE. Advantageous screening techniques and assays for evaluating a compound's therapeutic activity are also disclosed.

Abstract: Methods, systems and articles of manufacture for enhanced control over the positioning of dialog boxes in relation to hyperlinks within electronic documents. The controlled positioning is implemented to mitigate any undesirable placement of dialog boxes that might limit to user access to hyperlinks contained within the electronic document. Accordingly, embodiments are provided for determining a location within a displayed electronic document at which a dialog box may be positioned without obscuring any hyperlinks. In the event that such positioning is not possible, steps are taken to position the dialog box in a location that will result in the least interference between the user and a displayed document.

Abstract: The present invention relates to a blind rivet nut. Blind rivet nuts are used to connect items to surfaces of materials, such as roof racks to automobiles, and have proven to be extremely reliable. However, difficulties occur when attempting to connect to several layers of materials or when material thickness increase, as it has been necessary to increase hole size in order to ensure hole registration and this can cause sealing problems. The invention provides a blind rivet nut capable of being used through one or several layers with improved grip capability and improved sealing ability preventing ingress of moisture. Lines of weakness in the form of grooves are formed in a portion of the body of the blind rivet nut so that material deforms selectively thereby improving the grip of the blind rivet nut. A flange has an annular recess that enables an O-ring seal to deform more efficiently, giving a larger ‘footprint’ than was previously possible thereby enhancing sealing.

Abstract: An air filter assembly including abutting, cylindrical housing halves, with toothed outer ends, joined via spaced, T-shaped appendages; a cylindrical air inlet of abutting semi-cylindrical housing inlet portions; a primary filter pack, for slip-fit insertion into either housing half, having an end cap integral with a cylindrical primary filter pack having sealing material on its inner end; a filter outlet end with a toothed peripheral portion, for slip-fit insertion into and angular adjustment relative to either housing end, and a plurality of ribs defining locating surfaces for an air outlet portion, and main and safety filters; the latter having a truncated cone body and an inverted conical portion; and a filter attachment base having curved bed portions, for receiving a housing periphery portion, including spaced support pads and slot portions for angularly adjustably receiving like numbers of T-shaped appendages, with a locking mechanism joining the housing and attachment base.

Abstract: A platy pigment substrate having a carbon-containing coating thereon is provided wherein the coating comprises a pyrolyzed carbon-containing ionic species. The products of the present invention may be used in any application where pearlescent pigments have been used heretofore including but not limited to automotive and industrial paint applications.

Abstract: The present invention provides to a humanized monoclonal antibody having immunostimulatory effects. This antibody binds specifically to B lymphoblastoid cells, induces proliferation and activation of peripheral blood lymphocytes, and is capable of eliciting an anti-tumor effect upon administration to subjects suffering from cancer.

Abstract: A method and apparatus for a generator coil includes a plurality of stacked windings in a rotor where individual turns are stacked in parallel sided radial slots in the rotor. Each successive turn has the same width substantially corresponding to a constant width of each slot, wherein a first turn has a first thickness and a second turn has a second thickness thicker than said first thickness. The second turn is employed in regions of high temperature thereby reducing the temperature thereof.

Abstract: A method for testing for the presence of sol-gel on an aluminum test specimen includes: preparing an ammonium molybdate solution; preparing a hydrochloric acid solution; and mixing the solutions in 2:1 ratio in each of a number of receptacles. A test specimen of unknown coating, a first control specimen, and a second control specimen are placed in the mixed solution in three receptacles. The first control specimen has a sol-gel coating over an alodine coating; and the second control specimen has an alodine only coating. By timing events such as a change in color of the test and control specimens or the solution becoming opaque, the method determines that the test specimen of unknown coating has a like coating to that of a particular one of the control specimens if the timing of the event of the test specimen and the timing of the event of the particular control specimen are comparable.

Abstract: The invention is directed to a peel-type blind rivet assembly (110) for setting in relatively soft material and comprising an elongate tubular body (102) having a shank (106) with an enlarged head (108). A free end (114) of the shank, remote from the head (108), has an expandable portion formed by a plurality of slots (112) extending partway along the shank from this remote end (114). A mandrel (104) has a stem, and a mandrel head (126) with a maximum external diameter greater than the internal diameter of the body (102), wherein at least one of the plurality of slots (112) increases in width as it extends from an outer surface of the shank towards an inner surface of the shank. There is also provided a punch (280) for forming the tapered slots (112) in the rivet body, comprising an elongate solid body having a polygonal cross section wherein at least one convergence zone formed on an end face of the punch by the tapering convergence of two adjacent side walls forms a slot cutting element (285).

Abstract: The invention is directed to a peel-type blind rivet assembly (110) for setting in relatively soft material (152) and comprising an elongate tubular body (102) having a shank (106) with a enlarged head (108). A free end (114) of the shank, remote from the head (108), has an expandable portion formed by a plurality of slots (112) extending partway along the shank from this remote end (114). A mandrel (104) has a stem, and a mandrel head (126) with a maximum external diameter greater than the internal diameter of the body (102) such that the mandrel head (126) forms a shoulder (128) between the mandrel stem and an outer surface of the mandrel head, which shoulder (128) extends substantially perpendicular to the axis of the rivet body (102).

Abstract: Methods for increasing D-Serine concentration and reducing concentration of the toxic products of D-Serine oxidation, for enhancing learning, memory and/or cognition, or for treating schizophrenia, Alzheimer's disease, ataxia, or neuropathic pain, or preventing loss in neuronal function characteristic of neurodegenerative diseases involve administering to a subject in need of treatment a therapeutic amount of a compound of formula I, or a pharmaceutically acceptable salt or solvate thereof: wherein Z1 is N or CR3; Z2 is N or CR4; Z3is O or S; A is hydrogen, alkyl or M+; M is aluminum, calcium, lithium, magnesium, potassium, sodium, zinc or a mixture thereof; R1, R2, R3 and R4 are independently selected from hydrogen, alkyl, hydroxy alkoxy, aryl, acyl, halo, cyano, haloalkyl, NHCOOR5 and SO2NH2; R5 is aryl, arylalkyl, heteroaryl or heteroarylalkyl; at least one of R1, R2, R3 and R4 is other than hydrogen; and at least one of Z1 and Z2 is other than N.

Abstract: Methods for increasing D-Serine concentration and reducing concentration of the toxic products of D-Serine oxidation, for enhancing learning, memory and/or cognition, or for treating schizophrenia, Alzheimer's disease, ataxia or neuropathic pain, or preventing loss in neuronal function characteristic of neurodegenerative diseases involve administering to a subject in need of treatment a therapeutically effective amount of a compound of formula I, or a pharmaceutically acceptable salt or solvate thereof: wherein R1 and R2 are independently selected from hydrogen, halo, nitro, alkyl, acyl, alkylaryl, and XYR5; or R1 and R2, taken together, form a 5, 6, 7 or 8-membered substituted or unsubstituted carbocyclic or heterocyclic group; X and Y are independently selected from O, S, NH, and (CR6R7)n; R3 is hydrogen, alkyl or M+; M is aluminum, calcium, lithium, magnesium, potassium, sodium, zinc ion or a mixture thereof; Z is N or CR4; R4 is from selected from hydrogen, halo, nitro, alkyl, alkylaryl, and X

Abstract: Laser marking of plastic material is achieved by incorporating into the plastic a laser marking particulate additive having a particle size of less than 100 nm. A mixed oxide particle of tin and antimony having a particle size of 10-70 nm is useful as a laser marking additive when using a YAG laser. A metallic powder can further be added to improve marking contrast.

Abstract: The present invention relates to several C. elegans genes and gene products identified by means of RNA-mediated interference (RNAi) as required for the viability, growth or reproduction of nematodes and to functional orthologues of said genes and gene products found in other nematode species, including all biologically-active derivatives thereof. The invention also comprises the use of said genes and gene products in the development of anti-nematode or other pesticidal agents and in methods for diagnosis and treatment of diseases associated with the infection or presence of nematodes.

Abstract: A curved surfaces for adhering to contact surfaces is provided. The structure includes a curved surface with a plurality of nano-fibers disposed thereon. When the curved surface is in a first position, at least one of the plurality of nano-fibers contacts the contact surface and provides an adhesive force at the contact surface. When the curved surface rotates to a second position from the first position, the at least one of the plurality of nano-fibers is leveraged way from the contact surface.

Abstract: A method, apparatus, system, and signal-bearing medium that in an embodiment select a subset of windows displayed on an output device for display via an auxiliary output device, e.g., a projector. In various embodiments, the selection of the subset is based on a group affiliation or based on a list of allowed or disallowed applications. In other embodiments, the image on the auxiliary output device is selectively frozen or displays a pre-set image while the image on the output device changes. In this way, the displayed content on the auxiliary output device is selectively controlled, which allows for a more effective presentation.

Abstract: An out-feed roller support stand having a sturdy, stable base that folds for compact storage. A support mast that telescopes into and is adjustable within the base supports a work support head that includes an adjustable cross bar on which a row of pivoting caster wheels are mounted. An alternative embodiment includes a ramp for guiding sagging ends of work-pieces up onto the caster wheels. Both the height and angle between the adjustable cross bar and floor are adjustable after the position of the support mast has been adjusted in order to position the support head in roughly the correct location.

Abstract: A saddle square including a slot for aligning the square and marking a workpiece to ensure proper positioning of a stud.

Abstract: A method, apparatus and computer program product are provided for implementing enhanced notification and control features in an oscilloscope. User selected notification options and user selected control options are stored. When a predefined event is identified, the user selected notification options are used for notifying a remote user of the identified predefined event. The user selected control options are used for receiving user selections enabling the user to remotely control oscilloscope operational settings. The user can be notified with a telephone call, an email or a pager text message and the user can change operational settings using a telephone call or an email containing commands.