Abstract: An example voltage converter includes a transformer having a primary winding, a first secondary winding, and a second secondary winding; a first transistor connected between a first terminal of the first secondary winding and electrical ground, where the first transistor has a first drain; a second transistor connected between a second terminal of the second secondary winding and electrical ground, where the second transistor has a second drain; and a capacitor connectable along a current path to the transformer via at least one of the first transistor or the second transistor. A control system detects a first voltage at the first drain and a second voltage at the second drain, and generates pulse-width modulated control signals based at least on the first and second voltages to control operation of the first and second transistors to produce voltage at the primary winding based on a voltage across the capacitor.

Abstract: Techniques for deploying a server stack having a cross-server dependency are disclosed. A deployment engine initiates a deployment process for a server stack. The deployment engine provisions servers of one server type (“requisite servers”). The deployment engine attempts to provision servers of another server type (“dependent servers”). The deployment engine executes a test that requires the dependent servers to invoke a service executed by the requisite servers. Based on the test results, the deployment engine determines that an operational requirement of the dependent servers is not satisfied. The deployment engine modifies a configuration for the requisite servers to satisfy the operational requirement of the dependent servers. The deployment engine re-provisions the requisite servers using the modified configuration. The deployment engine completes the deployment process for the server stack.

Abstract: An MRI system (100) is proposed (for generating one or more images of a body-part of a patient under analysis); the MRI system (100) comprises an injector head assembly (155), for injecting at least one medical fluid into the patient, having a clock unit (340) for providing a clock signal with a clock frequency. The MRI system (100) comprises means (420-425; 445-460) for adjusting the clock frequency in response to a manual command and/or to a detection of a degradation of the images. An injector system (155,165) for use in this MRI system (100) is also proposed. Moreover, a corresponding method (500) for managing the injector head assembly (155) is proposed. A computer program (400) for implementing the method (500) and a corresponding computer program product are also proposed.

Abstract: The present invention provides T cell receptors (TCRs) having the property of binding to SLLMWITQC (SEQ ID NO: 126)-HLA-A*0201, the SLLMWITQC SEQ ID NO: 126 peptide being derived from the NY-ESO-1 protein which is expressed by a range of tumour cells. The TCRs have a KD for the said peptide-HLA complex of less than or equal to 104 and/or have an off-rate (koff) of 1×10?3 S?1 or slower.

Abstract: An example voltage converter includes a transformer having a primary winding, a first secondary winding, and a second secondary winding; a first transistor connected between a first terminal of the first secondary winding and electrical ground; a second transistor connected between a second terminal of the second secondary winding and electrical ground; an inductor connected to a center tap of the transformer between the first secondary winding and the second secondary winding; and a capacitor that is connectable along a current path to the transformer that includes the inductor via at least one of the first transistor or the second transistor. A control system generates, based on characteristics of current through the inductor, pulse-width modulated control signals to control operation of the first transistor and the second transistor to produce voltage at the primary winding based on a voltage across the capacitor.

Abstract: A cannulated retrograde reamer that is adjustable to create tunnels of multiple different diameters. The cannulated retrograde reamer substantially reduces the risk of tunnel malposition and/or misalignment, and can be adjusted to create a range of tunnel diameters, thereby allowing inventory levels to be reduced for a surgical case.

Abstract: A system for light source calibration and aging compensation is disclosed. In one or more embodiments, the system includes a light source driver, a sensor, and a controller. The light source driver is configured to generate one or more power signals for a plurality of light sources. The sensor is configured to detect an illumination power output by at least one light source of the plurality of light sources. The controller is communicatively coupled to the sensor and the light source driver. The controller is configured to compare the illumination power detected by the sensor to a target illumination power. The controller is further configured to generate one or more control signals to adjust an electrical power output of the light source driver based on the comparison of the illumination power detected by the sensor to the target illumination power.

Abstract: A gas turbine engine defining a radial direction is provided. The gas turbine engine includes a tie shaft; a compressor section including a last rotor stage, the compressor section assembled to a first portion of the tie shaft; a separable shaft disposed between the compressor section and the tie shaft, the separable shaft having a radial outward portion and a radial inward portion, the radial outward portion of the separable shaft in contact with a portion of the last rotor stage at an interface; and a seal assembly operable with a portion of the separable shaft proximate the radial inward portion.

Abstract: A needle tip storage and removal device comprises a storage compartment having a splined socket which engages complementary splines on a needle tip collar, the storage compartment being sealed by a peelable foil. Alongside the storage compartment is a removal compartment having a drive socket of similar configuration. The device assists safe removal and disposal of a used needle prior to fitting a new needle.

Abstract: Techniques for deploying a server stack having a cross-server dependency are disclosed. A deployment engine initiates a deployment process for a server stack. The deployment engine provisions servers of one server type (“requisite servers”). The deployment engine attempts to provision servers of another server type (“dependent servers”). The deployment engine executes a test that requires the dependent servers to invoke a service executed by the requisite servers. Based on the test results, the deployment engine determines that an operational requirement of the dependent servers is not satisfied. The deployment engine modifies a configuration for the requisite servers to satisfy the operational requirement of the dependent servers. The deployment engine re-provisions the requisite servers using the modified configuration. The deployment engine completes the deployment process for the server stack.

Abstract: In various embodiments, methods and systems for implementing a multi-device mixed interactivity system are provided. The interactivity system includes paired mixed-input devices for interacting and controlling virtual objects. In operation, a selection input associated with a virtual object is accessed. The selection input is based on real input associated with a selection device and virtual input associated with a mixed-reality device. The selection device has a first display that displays the virtual object and the mixed-reality device has a second display that displays the virtual object. A selection profile is generated based on the selection input. The selection profile comprises one or more selection profile attributes for isolating a portion of the virtual object. A selected portion of the virtual object is determined based on the selection profile. The selected portion of the virtual reality object is caused to be displayed on the first display of the selection device.

Abstract: A lid assembly that can be placed on a pan having a bottom surface that is configured for placement on a burner of the stove top with one or more foods to be cooked supported above an inner bottom surface of the pan by a rack. The lid assembly covers the pan and thereby encloses the one or more foods to be cooked and the rack within a cavity defined by the pan and the lid assembly. An air flow generator mounted on a shaft that extends through a cover portion of the lid from a motor disposed on an opposite side of the cover portion rotates the shaft to produce airflow within the cavity. The lid assembly cooks foods in less time and using less energy than normally required with a conventional oven.

Abstract: A method of operation triggers an alert when cameras or sensors determine an action e.g. entry into or occupancy of a reserved region. The system transmits a caution to the pilgrim to present a credential or affirm proper attire and safety equipage upon entry into the penumbra of the reserved region. Within the penumbra, a pilgrim may preempt the access control challenge or alert by presenting his credential or by signally his intention to enter the reserved region. A process of the surveillance and security system includes recording all entries and occupancy of reserved areas but suppressing alarms and alerts on the condition that a credential bearer is within the geo-fenced region. A reserved area has both umbra and penumbra regions with various effects of entry, occupancy, and presentation of credentials. Receiving a presented credential causes alerts to be preempted in the penumbra and to be unfaulted in the umbra.

Abstract: A clasp assembly includes a pair of identical half sections configured to be coupled to one another. Each half section comprises one or more deformable features that are designed to deform during closure to create an interlocking engagement between each half section.

Abstract: An exchange that fulfills natural language travel requests is described herein. According to some embodiments, systems for managing an exchange that fulfills natural language travel requests may include a publishing module that receives a plurality of inventory records from a plurality of suppliers, each of the plurality of inventory records pertaining to an available offering, the offering being defined by a set of metadata attributes, and a pattern recognition artificial intelligence engine that generates equivalent phrases for the set of metadata attributes from each inventory record by applying pattern recognition artificial intelligence to the set of metadata attributes, the equivalent phrases representing possible natural language queries to which an inventory record may correspond.

Abstract: The present invention concerns a syringe assembly comprising a hollow tubular syringe body, having a proximal end and a distal end, a plunger rod, axially movable in the syringe body between an initial position and a final position. The assembly also includes a support transversally stiff for supporting the plunger rod, the support having a distal end and a proximal end respectively transversally fixed to the syringe body and to the plunger rod, the proximal end of the support being movable with respect to the syringe body.

Abstract: A needle access assembly and method for obtaining percutaneous needle access with little or no fluoroscopy is disclosed. The method includes selecting a target for percutaneous access, directing a laser guide at a desired needle-insertion angle and in line with the selected target, aligning the needle access assembly with the laser, and inserting the needle into the target.

Abstract: Disclosed is a system for monitoring facial presentation of a first user to a second user. The system may include at least one image capturing device configured for capturing at least one image of the first user. Further, the system may include a communication device communicatively coupled to the at least one image capturing device. Further, the system may include a processing device communicatively coupled to the communication device. The communication device may be configured for transmitting the at least one image to a processing device. The processing device may be configured for analyzing the at least one image. The processing device may be configured for identifying a face of the first user based on the analyzing. Further, the processing device may be configured for generating facial presentation data based on the identifying. Further, the system may include a storage device configured for storing the facial presentation data.

Abstract: Described herein are compounds, such as compounds of Formula (I) and pharmaceutically acceptable salts thereof, that inhibit wild-type RET and its resistant mutants, pharmaceutical compositions including such compounds, and methods of using such compounds and compositions, e.g.

Abstract: Submersible transducer includes a transducer housing configured to be submerged within an aqueous liquid and a pressure sensor operable to obtain data for determining a pressure of the aqueous liquid. The pressure sensor may be disposed within the transducer housing. The submersible transducer also includes a submersible cable having an electrical conductor and a venting tube operably coupled to the pressure sensor. The pressure sensor uses an atmospheric pressure of an external environment that is detected through the venting tube to determine the pressure of the aqueous liquid. The submersible cable also includes a cable jacket and an inner layer that is surrounded by the cable jacket. The inner layer surrounds the electrical conductor and the venting tube. The inner layer includes a non-hygroscopic polymer that is more resistant to absorbing the aqueous liquid than the cable jacket.