Abstract: A method for configuring a field of view of a digital media frame. The method comprises analysing a digital image to identify at least one first portion of the digital image having a first predetermined characteristic. Determining an optimum location within the field of view. Positioning the identified at least one first portion of the digital image within the optimum location.

Abstract: The present disclosure relates to a method of removing a liner from a mill, the liner fastened to a mill shell by at least one liner bolt, the method including: (a) driving the at least one liner bolt through the mill shell until it becomes retained in the liner, whereby in a retained position, a head of the at least one liner bolt is exposed so as to project proud of the liner towards an interior of the mill; (b) engaging a tool onto the at least one liner bolt; and, (c) lifting the liner away from the mill shell using the tool to thereby enable the liner to be removed from the mill. A system for removing a liner from a mill and tool for use in removing a liner from a mill are also described.

Abstract: A toenail clipping device that provides support for the foot and toes so the toenails can be clipped. The Circular Mounted Toenail Clipper provides a stationary platform for the foot and the clipper is mounted on a rotating bearing assembly. This assembly allows the user to easily position the toenail clipper in relation to the stationary foot by providing a guide for the clipper that allows multiple axis of movement. The toenail clipper is attached to a circular stage and guided through an elongated handle. The circular stage allows the user to rotate the toenail clipper around the active toenail that needs clipping making the task easy. The toenail clipper has a force multiplier incorporated into the elongated handle enabling easy and controllable cutting of toenails.

Abstract: The instant disclosure relates generally to oral inoculation and specifically to methods to prepare nasopharyngeal and oral material for oral inoculation of COVID-19. Severe acute respiratory syndrome coronavirus 2 (“SARS-CoV-2”) viral particles are collected from at least one of a nasopharyngeal specimen and an oral specimen each derived from a patient infected with SARS-CoV-2 or a SARS-CoV-2 variant. Mammalian cells (e.g., Vero-E6 and/or Vero-CCL81 cells) are infected with the SARS-CoV-2 viral particles to produce infected mammalian cells. The infected mammalian cells are cultured to produce a mammalian cell culture. SARS-CoV-2 viral particles are collected from the mammalian cell culture to produce isolated viral particles. The isolated viral particles are frozen to produce a frozen isolate. The frozen isolate is partitioned into a plurality of tablets each having a therapeutically effective amount of the SARS-CoV-2 viral particles. An enteric coating is applied to each tablet.

Abstract: The subject method for delivering power to a moving target wirelessly via electromagnetic time reversal can find applications in wireless electrical transmission to portable devices, wireless heating of portable devices, novel wirelessly powered accelerometers, hyperthermic treatment of cancers, and many other applications. The subject non-linear time reversed electromagnetic waves based wireless power transmission (WPT) system targets either a single linear or non-linear object where a selective targeting between two diodes has been demonstrated simultaneously with different degrees of non-linearity in a three-dimensional ray-chaotic billiard model. A dual-purpose rectenna with harmonic generation for wireless power transfer by non-linear time-reversal has been designed for the subject system using the Schottky diode.

Abstract: Provided herein are methods of increasing mucus clearance in a subject having decreased mucus clearance. Also provided are methods of treating or preventing a respiratory disorder.

Abstract: An oscillatory therapy device has a nebulizer port (21) close to a patient inlet (12) and a first one way valve (31) between the nebulizer port and the oscillatory mechanism (20) arranged to allow expiratory flow from the patient inlet to the mechanism but to prevent flow in the opposite direction. The nebulizer port (21) includes a second one-way valve (32) arranged to open during inhalation but to close during exhalation so that nebulizer medication is not expelled during exhalation.

Abstract: Provided are articles, kits, and methods for teaching a person how to tie a bow tie. A practice bow tie includes an elongated piece of flexible material with indicators on the front and rear surface of the bow tie. The indicators, also provided in a kit, define a portion, fold line, or step that aid a user in tying a bow tie to achieve a satisfactory appearance.

Abstract: A client application is specified by a target tenant and represented in an OAuth provider, along with a corresponding secret. A source tenant consents to permissions to be executed by the client application on a resource of the source tenant. A target service uses the secret to obtain an access token from an authorization server coupled to the source tenant and uses the access token to obtain access, specified by the permissions, to the resource served by a source service acting on behalf of the source tenant.

Abstract: This invention relates to inhibitors of NTRK that are active against wild-type NTRK and its resistant mutants.

Abstract: This disclosure relates to inhibitors of NTRK that are active against wild-type NTRK and its resistant mutants, such as compounds of Formula (I):

Abstract: A digital communication method, comprising: providing a digital packet radio transceiver which communicates through an antenna array, defining a directional pattern with distinct spatial communication channels using a plurality of frequency channels; detecting channel conditions based on a feedback protocol between the digital packet radio transceiver and a remote digital packet radio system, selectively controlling the digital packet transceiver to transmit information responsive to the channel conditions; detecting another digital packet radio transceiver concurrently using the same frequency channels, and selectively controlling an interference with the other digital packet radio transceiver in dependence on information from the other digital packet radio transceiver, by one of deferring to transmissions by the other digital packet radio transceiver, and competing with transmissions by the other digital packet radio transceiver.

Abstract: In various embodiments, methods and systems for implementing a multi-device mixed interactivity system are provided. The interactivity system includes paired mixed-input devices for interacting and controlling virtual objects. In operation, a selection profile associated with a virtual object is accessed. The selection profile is generated based on a selection input determined using real input associated with a selection device and virtual input associated with a mixed-reality device. The selection device has a first display and the mixed-reality device has a second display that both display the virtual object. An annotation input for the virtual object based on a selected portion corresponding to the selection profile is received. An annotation profile based on the annotation input is generated. The annotation profile includes annotation profile attributes for annotating a portion of the virtual object. An annotation of the selected portion of the virtual reality object is caused to be displayed.

Abstract: A method of forming a tool includes applying a first build ply to an initial ply. A second build ply is applied to the first build ply. Successive build plies are applied to build on the second build ply, the successive build plies including a medial section of build plies and a last build ply. A surface defined by the last build ply, the first build ply, and leading edges of the build plies therebetween define a substantially curvature-continuous surface profile extending between a first segment and a second segment. A shape of the substantially curvature-continuous surface profile is determined based on an adjusted ply drop ratio for at least a portion of the successive build plies.

Abstract: Ice test devices include an ice adhesion test device. The ice adhesion test device comprises an ice adhesion test target in the form of a well in which, in use, a layer of accreted ice is built up. The target comprises a sample plate at the bottom of the well and an ice-engagement element positioned circumferentially around the sample plate and providing a side wall of the well, and wherein the sample plate is rotatable relative to the ice-engagement element. The ice adhesion test device also comprises torque means for applying a rotational torque between the sample plate and the ice-engagement element. The ice adhesion test device also comprises transducer means for, at least at a point at which the layer of accreted ice separates from the sample plate, measuring the rotational torque and/or the stress on the ice.

Abstract: A cannulated retrograde reamer that is adjustable to create tunnels of multiple different diameters. The cannulated retrograde reamer substantially reduces the risk of tunnel malposition and/or misalignment, and can be adjusted to create a range of tunnel diameters, thereby allowing inventory levels to be reduced for a surgical case.

Abstract: One example discloses an acoustic device, including: a first input configured to receive a first ambient input signal from a first acoustic transducer; a second input configured to receive a second ambient input signal from a second acoustic transducer; a first output configured to transmit a first ambient output signal; a second output configured to transmit a second ambient output signal; an ambient signal characterization circuit configured to identify an undesired ambient signal within the first and/or second ambient input signals; and an ambient signal control circuit configured to control how the acoustic device generates the first and second ambient output signals from the first and second ambient input signals based on the undesired ambient signal.

Abstract: One example discloses an acoustic device, including: a first input configured to receive a first ambient input signal from a first acoustic transducer; a second input configured to receive a second ambient input signal from a second acoustic transducer; a first output configured to transmit a first ambient output signal; a second output configured to transmit a second ambient output signal; an ambient signal characterization circuit configured to identify an undesired ambient signal within the first and/or second ambient input signals; and an ambient signal control circuit configured to control how the acoustic device generates the first and second ambient output signals from the first and second ambient input signals based on the undesired ambient signal.

Abstract: Access to data and resources in a multi-tenant computing system is managed by tagging the data and resources with attributes, as well as by tagging users with attributes. Tenant-specific access policies are configured. When an access request is received from a workload, a policy decision engine processes the attributes that are tagged to the requesting workload (e.g., user, application, etc.) as well as those tagged to the requested data or resource, given a relevant tenant-specific policy. An access decision is provided in response to the access request, and the access decision can be enforced by a tenant-specific enforcement system.

Abstract: An example voltage converter includes a transformer having a primary winding, a first secondary winding, and a second secondary winding; a first transistor connected between a first terminal of the first secondary winding and electrical ground, where the first transistor has a first drain; a second transistor connected between a second terminal of the second secondary winding and electrical ground, where the second transistor has a second drain; and a capacitor connectable along a current path to the transformer via at least one of the first transistor or the second transistor. A control system detects a first voltage at the first drain and a second voltage at the second drain, and generates pulse-width modulated control signals based at least on the first and second voltages to control operation of the first and second transistors to produce voltage at the primary winding based on a voltage across the capacitor.