Abstract: A ride control system includes a central controller configured to synchronize movements of separate groups of ride vehicles along a path. Each of the separate groups of ride vehicles includes multiple individual ride vehicles unconnected to one another and forming a virtual train. Each virtual train is assigned one or more schedules having multiple expected positions along the path and multiple expected timestamps. Each of the expected timestamps of the multiple expected timestamps are associated with respective expected positions of the multiple expected positions. The ride control system also includes multiple vehicle controllers. Each vehicle controller of the multiple vehicle controllers is communicatively coupled to a respective individual ride vehicle of the multiple individual ride vehicles. Each vehicle controller is configured to control a speed of the respective individual ride vehicle along the path based at least on the one or more schedules.

Abstract: An electrosurgical instrument for applying to biological tissue RF electromagnetic energy and/or microwave frequency EM energy, wherein the instrument tip has a protective hull with a smoothly contoured convex undersurface facing away from a planar body, and wherein the planar body has a tapering distal edge, and wherein an underside of the planar body extends beyond the protective hull at the tapering distal edge. Also disclosed herein is an interface joint for integrating into a single cable assembly all of (i) a fluid feed, (ii) a needle movement mechanism, and (iii) an energy feed (e.g. a coaxial cable), and a torque transfer device for permitting controlled rotation of the cable assembly within the instrument channel of an endoscope. The interface joint and torque transfer device may be integrated as a single component.

Abstract: The present invention generally relates to the field of data encryption processes for crypto-currency or other digital asset transactions between a principal and beneficiary utilizing a custodian. Cryptographic protocols protect the asset from the custodian. It can also protect the asset from the principal. It can also protect the asset against the beneficiary until such time as the beneficiary can prove certain logical conditions that give it exclusive control over the digital asset.

Abstract: The present invention generally relates to the field of data encryption processes for crypto-currency or other digital asset transactions between a principal and beneficiary utilizing a custodian. Cryptographic protocols protect the asset from the custodian. It can also protect the asset from the principal. It can also protect the asset against the beneficiary until such time as the beneficiary can prove certain logical conditions that give it exclusive control over the digital asset.

Abstract: The invention provides a molecule that modulates an activity of a Src family kinase for use in preventing or treating a metastatic cancer a subject. Preferably, the molecule comprises or consists of the structure: Bj-[(Pro)n-Xr-His-Pro-His-Ala-Arg-Ile-Lys]m-Rp, or Bj-[lys-ile-arg-ala-his-pro-his-xr-(pro)n]m-Rp, or a derivative or fragment thereof, wherein B is a first chemical moiety, j is 0 or 1, n is an integer from 1-10, X is any amino acid, r is an integer from 0 to 2, m is an integer from 1 to 3, R is a second chemical moiety, p is 0 or 1, and [lys-ile-arg-ala-his-pro-his-xr-(pro)n] is the retro-inverso peptide of [(Pro)n-Xr-His-Pro-His-Ala-Arg-Ile-Lys].

Abstract: An electrosurgical resection instrument for applying to biological tissue radiofrequency electromagnetic energy has a protective hull comprising a shaped piece of dielectric material mounted to cover an underside of an instrument tip of the instrument. The protective hull acts as a shield to protect tissue that may lie under the instrument tip from damage during treatment. The instrument may be particularly useful in procedures performed in a gastrointestinal tract, where bowel perforation concern, or in the pancreas, where damage to the portal vein or the pancreatic duct may occur when a tumor or other abnormality is being resected, dissected or removed.

Abstract: Systems, devices, and methods for evaluating an earth formation. Apparatus include an electrically conducting tubular; at least one transmitter configured to propagate an electromagnetic field in the earth formation; and at least one receiver configured to receive an electromagnetic signal resulting from interaction of an electromagnetic field with said earth formation. The at least one transmitter and at least one receiver may employ antenna assemblies comprising: a recess in the conducting tubular defined by at least one radially extending surface substantially perpendicular to a longitudinal axis of the conducting tubular and non-radially extending surfaces; an antenna in the recess; and conductive shielding, the conductive shielding having a conductivity significantly more than a conductivity of the conducting tubular and covering the whole of each of the plurality of radially extending surfaces.

Abstract: An electrosurgical resection instrument for applying to biological tissue radiofrequency electromagnetic energy has a protective hull comprising a shaped piece of dielectric material mounted to cover an underside of an instrument tip of the instrument. The protective hull acts as a shield to protect tissue that may lie under the instrument tip from damage during treatment. The instrument may be particularly useful in procedures performed in a gastrointestinal tract, where bowel perforation is a concern, or in the pancreas, where damage to the portal vein or the pancreatic duct may occur when a tumor or other abnormality is being resected, dissected or removed.

Abstract: An electrosurgical cutting tool comprising a pair of pivotable blades that are mechanically operable as scissors or pliers. The blades have electrodes capable of delivery RF and/or microwave energy to cut or coagulate tissue between them. The tool combines the actuation and energy delivery mechanisms in a compact arrangement that enables the tool to be inserted through an instrument channel of a surgical scoping device, such as an endoscope, gastroscope or laparoscope. Each blade may comprise a planar body made of dielectric material that separates a first conductive element from a second conductive element. The blades may rotate relative to each other in the plane of the blades.

Abstract: A ride control system for controlling a plurality of vehicles on a path includes a path processor and a bi-directional voting circuit in circuit with the path processor. Each vehicle of the plurality of vehicles may include a vehicle processor supported by the at least one vehicle and shunt relays in circuit with the at least one vehicle processor. Each vehicle processor may be configured to close a respective shunt relay upon a predetermined condition of the vehicle whereby the bi-directional voting circuit is activated to notify all other vehicles.

Abstract: The invention includes an XRF analyzer with reduced x-ray attenuation between sample and target and between sample and detector. Attenuation can be reduced by removing atmospheric-air paths through which the x-rays must travel. Reduced x-ray attenuation can allow for easier detection of low-atomic-number elements. Cost saving can be achieved by reducing the number of x-ray windows.

Abstract: A narrow profile surgical ligation clip has two legs with clamping surfaces joined by a hinge near the proximal ends, allowing the clip to reversibly open and close. A locking mechanism is proximal to the hinge to bias or lock the clip closed, including first and second jaw structures spaced on opposite sides of a longitudinal axis of the clip thereby defining a locking space therebetween. In one embodiment, a wedge or buttress body moves by application of an external force applied to a proximal end of the clip towards the hinge to move into the locking space such that one or more outer surfaces or projections of portions of the body fit into or abut against complementary surfaces or other parts of the locking mechanism or clip assembly to bias or lock the clip in a closed position and provide additional closing force to the inner clamping surfaces.

Abstract: Electrical instrument for applying radiofrequency and/or microwave frequency energy to tissue, comprising: a distal part comprising an instrument tip for applying radiofrequency and/or microwave frequency energy to tissue, the instrument tip comprising first and second conductive elements: a coaxial feed cable comprising an inner conductor, a tubular outer conductor coaxial with the inner conductor, and dielectric material separating the inner and outer conductors, the coaxial feed cable being for conveying radiofrequency and/or microwave frequency energy to the distal part; wherein: the inner conductor is electrically connected to the first conductive element and the outer conductor is electrically connected to the second conductive element through a rotatable connection between the distal part and the coaxial feed cable that allows rotation of the distal part relative to the coaxial feed cable: and the instrument comprises an actuator for rotating the distal part in a first rotational direction relative to

Abstract: An applier for ligation clip is provided. The applier includes: an outer tube having mounting bosses; a pair of jaws pivotally connected to the mounting bosses, the jaws having actuating projections; a feed tube located in the outer tube and configured to move axially within the outer tube, the feed tube having actuating slots in which the actuating projections are located; a clip lock arm located in the outer tube and configured to move axially within the outer tube; and a clip advance arm located in the outer tube and configured to move axially within the outer tube, the clip advance arm having flexible pinchers at one end of the clip advance arm. A method of applying a ligation clip is also disclosed.

Abstract: The invention provides a molecule that inhibits or prevents an interaction between a Src family kinase and an androgen or estradiol receptor, for use in preventing or treating a non-cancerous condition in which an activity of AR and/or ER is a contributory factor in a subject, or for use in preventing or treating a cancerous condition in which an activity of AR and/or ER is a contributory factor in a subject who wishes to preserve fertility, or for use in preventing or treating a gynaecological condition in which an activity of AR and/or ER is a contributory factor in a subject.

Abstract: The disclosure relates to three enhancements for a surgical snare: an electrosurgical snare in which the loop of snare wire extends from an energy transfer surface which can act both as a physical reaction surface for mechanical cutting using the snare and as a region for emitting electromagnetic energy; a surgical snare having a snare wire having a first end connected to a movable boss that is slidably mounted on a coaxial cable; and a surgical snare having an end cap with a distally facing reaction surface and a pair of channels for guiding a snare wire, where the distally facing reaction surface is arranged to contact the retractable loop when fully retracted.

Abstract: The invention provides a molecule that inhibits or prevents an interaction between a Src family kinase and an androgen or estradiol receptor, for use in preventing or treating a non-cancerous condition in which an activity of AR and/or ER is a contributory factor in a subject, or for use in preventing or treating a cancerous condition in which an activity of AR and/or ER is a contributory factor in a subject who wishes to preserve fertility, or for use in preventing or treating a gynecological condition in which an activity of AR and/or ER is a contributory factor in a subject.

Abstract: A ride control system includes a central controller configured to synchronize movements of separate groups of ride vehicles along a path. Each of the separate groups of ride vehicles includes multiple individual ride vehicles unconnected to one another and forming a virtual train. Each virtual train is assigned one or more schedules having multiple expected positions along the path and multiple expected timestamps. Each of the expected timestamps of the multiple expected timestamps are associated with respective expected positions of the multiple expected positions. The ride control system also includes multiple vehicle controllers. Each vehicle controller of the multiple vehicle controllers is communicatively coupled to a respective individual ride vehicle of the multiple individual ride vehicles. Each vehicle controller is configured to control a speed of the respective individual ride vehicle along the path based at least on the one or more schedules.

Abstract: Apparatuses and methods are provided herein that may improve sensitivity to transient signals. For example, an electromagnetic sensor for downhole measurements that includes a plurality of sectors (e.g., four quadrants) is provided herein. Each quadrant may include a magnetic core formed of a material with a high initial magnetic permeability to improve sensitivity to transient signals. A sensor for continuous wave induction tools is also provided, and may include a magnetic core formed of a material with a high initial magnetic permeability. Forming each sector magnetic core of a material with a high mechanical reliability may allow the magnetic core of the corresponding sensor to be pliable and flexible and not brittle and prone to breaking. Furthermore, the corresponding sensor may have enhanced sensitivity, greater stability of sensitivity relative to temperature changes, and high mechanical reliability.

Abstract: Embodiments of the invention provide a hollow cable for conveying radiofrequency and/or microwave frequency energy to an electrosurgical instrument that can fit within, e.g. slide relative to, the hollow cable. The hollow cable provides a bipolar electrical connection to the electrosurgical instrument that is maintained when the electrosurgical instrument is rotated relative to the hollow cable. The cable may comprise a hollow coaxial transmission line having a rotatable component mounted at its distal end. The rotatable component comprises a longitudinal passageway continuous with the hollow coaxial transmission line. The rotatable component is rotatable relative to the transmission line and comprises a first and second conductive portions that are respectively electrically connected to first and second terminals on the coaxial transmission line and which are configured to maintain an electrical connection with their respective terminal when rotated relative to the coaxial transmission line.