Abstract: The present invention relates to immunogenic compositions, comprising polypeptides and polysaccharides from Staphylococcus aureus. The present invention also relates to immunogenic compositions, comprising Staphylococcus aureus capsule polysaccharides conjugated to a carrier protein. In addition, the invention relates to methods of inducing an immune response in subjects against Staphylococcus aureus using immunogenic compositions of the Staphylococcus aureus polypeptides and capsule polysaccharides.

Abstract: A ride control system for controlling a plurality of vehicles on a path includes a path processor and a bi-directional voting circuit in circuit with the path processor. Each vehicle of the plurality of vehicles may include a vehicle processor supported by the at least one vehicle and shunt relays in circuit with the at least one vehicle processor. Each vehicle processor may be configured to close a respective shunt relay upon a predetermined condition of the vehicle whereby the bi-directional voting circuit is activated to notify all other vehicles.

Abstract: The present invention relates to immunogenic compositions, comprising polypeptides isolated from Staphylococcus epidermidis. The invention also relates to polynucleotides encoding Staphylococcus epidermidis polypeptides and their use in immunogenic compositions. In addition, the invention relates to methods of inducing an immune response in mammals against Staphylococcus epidermidis and Staphylococcus aureus using immunogenic compositions of the Staphylococcus epidermidis polypeptides and polynucleotides. The invention also relates to methods for detecting Staphylococcus epidermidis in a biological sample.

Abstract: Systems, devices, and methods for evaluating an earth formation. Methods may include inducing a current in the formation; measuring a time-dependent transient electromagnetic (TEM) signal induced by the formation responsive to the current; and estimating apparent resistivity values for each of a plurality of samples derived from the TEM measurement, wherein each sample corresponds to a discrete time window of the TEM measurement. Estimating the apparent resistivity values for each of the samples includes determining for each sample a simulated homogeneous formation that provides a best fit for the sample. The apparent resistivity values may be used to estimate distance to an interface. The apparent resistivity values or the estimated distance may be logged and the log displayed. The apparent resistivity values, the estimated distance, or the log may be used to conduct further operations in a borehole, including geosteering.

Abstract: The present invention relates to immunogenic compositions, comprising polypeptides and polysaccharides from Staphylococcus aureus. The present invention also relates to immunogenic compositions, comprising Staphylococcus aureus capsule polysaccharides conjugated to a carrier protein. In addition, the invention relates to methods of inducing an immune response in subjects against Staphylococcus aureus using immunogenic compositions of the Staphylococcus aureus polypeptides and capsule polysaccharides.

Abstract: Apparatuses and methods are provided herein that may improve sensitivity to transient signals. For example, an electromagnetic sensor for downhole measurements that includes a plurality of sectors (e.g., four quadrants) is provided herein. Each quadrant may include a magnetic core formed of a material with a high initial magnetic permeability to improve sensitivity to transient signals. A sensor for continuous wave induction tools is also provided, and may include a magnetic core formed of a material with a high initial magnetic permeability. Forming each sector magnetic core of a material with a high mechanical reliability may allow the magnetic core of the corresponding sensor to be pliable and flexible and not brittle and prone to breaking. Furthermore, the corresponding sensor may have enhanced sensitivity, greater stability of sensitivity relative to temperature changes, and high mechanical reliability.

Abstract: A ride control system for controlling a plurality of vehicles on a path includes a path processor and a bi-directional voting circuit in circuit with the path processor. Each vehicle of the plurality of vehicles may include a vehicle processor supported by the at least one vehicle and shunt relays in circuit with the at least one vehicle processor. Each vehicle processor may be configured to close a respective shunt relay upon a predetermined condition of the vehicle whereby the bi-directional voting circuit is activated to notify all other vehicles.

Abstract: The present invention relates to immunogenic compositions, comprising polypeptides and polysaccharides from Staphylococcus aureus. The present invention also relates to immunogenic compositions, comprising Staphylococcus aureus capsule polysaccharides conjugated to a carrier protein. In addition, the invention relates to methods of inducing an immune response in subjects against Staphylococcus aureus using immunogenic compositions of the Staphylococcus aureus polypeptides and capsule polysaccharides.

Abstract: The invention provides a molecule that inhibits or prevents an interaction between a Src family kinase and an androgen or estradiol receptor, for use in preventing or treating a non-cancerous condition in which an activity of AR and/or ER is a contributory factor in a subject, or for use in preventing or treating a cancerous condition in which an activity of AR and/or ER is a contributory factor in a subject who wishes to preserve fertility, or for use in preventing or treating a gynaecological condition in which an activity of AR and/or ER is a contributory factor in a subject.

Abstract: A sterilisation or disinfecting system in which non-thermal plasma is generated in pulses, in which pulses of microwave frequency energy are used to sustain each plasma pulse, and a detectable characteristic of each pulse of microwave energy is used to trigger a radiofrequency strike pulse which strikes the plasma. The system includes a strike signal generation circuit arranged to condition and/or process the signal from the microwave signal coupler to form a control signal based on the detectable characteristic, which may be the rising edge or amplitude of the pulse.

Abstract: A method of synchronization between downhole components includes: generating a dual tone synchronization signal by a signal generator in a first downhole component disposed in a borehole in an earth formation, the dual tone signal including a first constituent periodic signal having a first frequency f1 and a second constituent periodic signal having a second frequency f2 that is different from the first frequency; transmitting the synchronization signal to a second downhole component disposed in the borehole; receiving the synchronization signal by a signal processor in the second downhole component, calculating a phase difference between the first constituent signal and the second constituent signal, and calculating a transmission delay based on the phase difference; and synchronizing operation of the first and second downhole components based on the delay.

Abstract: The present invention relates to immunogenic compositions, comprising polypeptides and polysaccharides from Staphylococcus aureus. The present invention also relates to immunogenic compositions, comprising Staphylococcus aureus capsule polysaccharides conjugated to a carrier protein. In addition, the invention relates to methods of inducing an immune response in subjects against Staphylococcus aureus using immunogenic compositions of the Staphylococcus aureus polypeptides and capsule polysaccharides.

Abstract: An apparatus for estimating a property of an earth formation penetrated by a borehole includes: a borehole carrier; a first switchable-magnet; a first energy storage device coupled to the first switchable magnet; a second switchable-magnet; a second energy storage device coupled to the second switchable-magnet; at least one voltage source having a first polarity and a second polarity opposite of the first polarity; and an electrical circuit configured to charge the first energy storage device and the second energy storage device at the same time and to sequentially discharge the first energy storage device and the second energy storage device, the electrical circuit being further configured to charge the first and second energy storage devices to the first polarity and then charge the first and second energy storage devices to the second polarity after the first and second energy storage devices are discharged.

Abstract: The present invention relates to immunogenic compositions, comprising polypeptides and polysaccharides from Staphylococcus aureus. The present invention also relates to immunogenic compositions, comprising Staphylococcus aureus capsule polysaccharides conjugated to a carrier protein. In addition, the invention relates to methods of inducing an immune response in subjects against Staphylococcus aureus using immunogenic compositions of the Staphylococcus aureus polypeptides and capsule polysaccharides.

Abstract: An applier for ligation clip is provided. The applier includes: an outer tube having mounting bosses; a pair of jaws pivotally connected to the mounting bosses, the jaws having actuating projections; a feed tube located in the outer tube and configured to move axially within the outer tube, the feed tube having actuating slots in which the actuating projections are located; a clip lock arm located in the outer tube and configured to move axially within the outer tube; and a clip advance arm located in the outer tube and configured to move axially within the outer tube, the clip advance arm having flexible pinchers at one end of the clip advance arm. A method of applying a ligation clip is also disclosed.

Abstract: A narrow profile surgical ligation clip has two legs with clamping surfaces joined by a hinge near the proximal ends, allowing the clip to reversibly open and close. A locking mechanism is proximal to the hinge to bias or lock the clip closed, including first and second jaw structures spaced on opposite sides of a longitudinal axis of the clip thereby defining a locking space therebetween. In one embodiment, a wedge or buttress body moves by application of an external force applied to a proximal end of the clip towards the hinge to move into the locking space such that one or more outer surfaces or projections of portions of the body fit into or abut against complementary surfaces or other parts of the locking mechanism or clip assembly to bias or lock the clip in a closed position and provide additional closing force to the inner clamping surfaces.

Abstract: The present invention relates to immunogenic compositions, comprising polypeptides isolated from Staphylococcus epidermidis. The invention also relates to polynucleotides encoding Staphylococcus epidermidis polypeptides and their use in immunogenic compostions. In addition, the invention relates to methods of inducing an immune response in mammals against Staphylococcus epidermidis and Staphylococcus aureus using immunogenic compostions of the Staphylococcus epidermidis polypeptides and polynucleotides. The invention also relates to methods for detecting Staphylococcus epidermidis in a biological sample.

Abstract: Immunogenic polysaccharide-protein conjugates having a polysaccharide antigen (or its oligosaccharide fragment representing one or more antigenic epitopes) derived from a nosocomial pathogen conjugated to a staphylococcal surface adhesin carrier protein are used in immunogenic compositions to elicit antibody responses to both the polysaccharide antigen and the staphylococcal surface adhesin carrier protein. Such immunogenic compositions are used to immunize against diseases caused by Staphylococcal aureus, Staphylococcal epidermidis or other nosocomial pathogens.

Abstract: The present invention relates to immunogenic compositions, comprising polypeptides and polysaccharides from Staphylococcus aureus. The present invention also relates to immunogenic compositions, comprising Staphylococcus aureus capsule polysaccharides conjugated to a carrier protein. In addition, the invention relates to methods of inducing an immune response in subjects against Staphylococcus aureus using immunogenic compositions of the Staphylococcus aureus polypeptides and capsule polysaccharides.

Abstract: A method for creating a customized TV/radio service from user-selected contents is disclosed. The method is applied to a playback device for receiving a number of digital audio/video services. The method includes decoding the received digital audio/video services to obtain a plurality of content elements and metadata corresponding to the content elements; examining the digital audio/video services to determine breaks between the content elements; checking the associated metadata for each content element against a list of user-provided keywords/genres corresponding to the user-selected contents; recording the content elements, a plurality of advertisements and associated keywords describing contents of the advertisements when the corresponding metadata substantially match at least one of the user-selected contents; and constructing a playlist of the recorded contents for the user to create the customize TV/radio service when the user wishes to play the recorded contents.