Abstract: A ventilator system (10) comprising: a ventilator (110) operable to provide forced mechanical ventilation; a breathing pattern controller (111) configured to operate the ventilator according to a breathing pattern; and a breathing pattern communication unit (112) operable to in use transmit a trigger signal, according to the breathing pattern. The ventilator system (10) may further comprises an associated medical device (113), with the breathing pattern communication unit (112) configured to transmit a trigger signal to the associated medical device (113).

Abstract: Some embodiments of the present invention provide apparatus for detecting particles of radiation comprising: a plurality of solid state semiconductor detector devices provided at spaced apart locations along a beam axis, the detector devices each being configured to generate an electrical signal indicative of passage of a particle through or absorption of a particle by the device; and at least one absorber portion configured to absorb at least a portion of an energy of a particle, wherein one said at least one absorber portion is provided in a particle path between at least one pair of adjacent detector devices, the apparatus being configured to provide an output signal indicative of the energy of a particle, the output signal provided being dependent on the electrical signals indicative of passage of a particle through or absorption of a particle by the devices.

Abstract: A non-leaching mediator may include a polymer having a polymeric backbone, and a plurality of phenothiazine groups bonded to the polymeric backbone. The plurality of phenothiazine groups may include at least one of a phenothiazine group having the general formula (IV): and salts thereof, where n is about 9 and “R” represents the polymeric backbone to which the phenothiazine group is bonded, and a phenothiazine group having the general formula (V): and salts thereof, where n is about 9 and “R” represents the polymeric backbone to which the phenothiazine group is bonded.

Abstract: A non-leaching mediator may include a polymer having a polymeric backbone, and a plurality of phenothiazine groups bonded to the polymeric backbone. The plurality of phenothiazine groups may include at least one of a phenothiazine group having the general formula (IV): and salts thereof, where n is about 9 and “R” represents the polymeric backbone to which the phenothiazine group is bonded, and a phenothiazine group having the general formula (V): and salts thereof, where n is about 9 and “R” represents the polymeric backbone to which the phenothiazine group is bonded.

Abstract: The invention relates to an insulated conductor comprising an elongate conductor provided with an insulating layer which comprises a polymeric material. Said polymeric material has a crystallinity of at least 25% and includes a repeat unit of general formula wherein t1 and w1 independently represent 0 or 1 and v1 represents 0, 1 or 2. The insulating layer has a thickness in the range 2 ?m-300 ?m.

Abstract: A component comprising a first part and a second part, wherein a third part is positioned between the first and second parts, wherein: (iv) said first part comprises a polymeric material (A) which comprises a repeat unit of formula (XI) wherein t1, and w1 independently represent 0 or 1 and v1 represents 0, 1 or 2; (v) said second part comprises a polymeric material (B) which comprises a repeat unit of formula (XI) wherein t1, and w1 independently represent 0 or 1 and v1 represents 0, 1 or 2; and (vi) said third part comprises a polymeric material (C) which comprises a polymer having a repeat unit of formula —O-Ph-O-Ph-CO-Ph-??I and a repeat unit of formula —O-Ph-Ph-O-Ph-CO-Ph-??II wherein Ph represents a phenylene moiety.

Abstract: Some embodiments of the present invention provide a 2D position-sensitive detector assembly comprising at least three substantially planar detector portions arranged in overlapping relationship as viewed normal to a plane of the detector portions, each detector portion comprising an array of substantially parallel, linear detector elements, the detector elements of respective detector portions being mutually non-parallel, the detector elements each being configured to generate one or more electrical signals in response to interaction of a particle of radiation therewith.

Abstract: Some embodiments of the present invention provide apparatus having a particle beamline for passage of charged particles of radiation therealong, comprising: a first beam tracker structure comprising at least one position sensitive detector (PSD) for determining a location with respect to a cross-sectional area of the beam line at which particles pass through the PSD; energy discrimination apparatus for determining an energy of particles that have passed through the first beam tracker structure; and support means for supporting a subject in a path of a particle along the beamline between the first beam tracker structure and the energy discrimination apparatus, the apparatus being configured to be operated in a selected one of a first mode and a second mode, the apparatus being configured, in the first mode of operation, to control an energy of the beam of charged particles passing through the first beam tracker structure such that a Bragg peak of charged particle absorption is located within the subject, and i

Abstract: Some embodiments of the present invention provide apparatus for detecting particles of radiation comprising: a plurality of solid state semiconductor detector devices provided at spaced apart locations along a beam axis, the detector devices each being configured to generate an electrical signal indicative of passage of a particle through or absorption of a particle by the device; and at least one absorber portion configured to absorb at least a portion of an energy of a particle, wherein one said at least one absorber portion is provided in a particle path between at least one pair of adjacent detector devices, the apparatus being configured to provide an output signal indicative of the energy of a particle, the output signal provided being dependent on the electrical signals indicative of passage of a particle through or absorption of a particle by the devices.

Abstract: A non-leaching mediator may include a polymer having a polymeric backbone, and a plurality of phenothiazine groups bonded to the polymeric backbone. The plurality of phenothiazine groups may include at least one of a phenothiazine group having the general formula (IV): and salts thereof, where n is about 9 and “R” represents the polymeric backbone to which the phenothiazine group is bonded, and a phenothiazine group having the general formula (V): and salts thereof, where n is about 9 and “R” represents the polymeric backbone to which the phenothiazine group is bonded.

Abstract: A non-leaching mediator may include a polymer having a polymeric backbone, and a plurality of phenothiazine groups bonded to the polymeric backbone. The plurality of phenothiazine groups may include at least one of a phenothiazine group having the general formula (IV): and salts thereof, where n is about 9 and “R” represents the polymeric backbone to which the phenothiazine group is bonded, and a phenothiazine group having the general formula (V): and salts thereof, where n is about 9 and “R” represents the polymeric backbone to which the phenothiazine group is bonded.

Abstract: A method for treating a complex fracture with a variable length nail is provided. The nail is configured for at least 5 mm of axial length change in each direction. The method involves making a first hole or incision in the skin of the patient in proximity to a fractured long bone and at least partially clearing a canal through the center of the long bone. The variable length nail is inserted into the canal and securing a distraction shaft and a housing of the nail to separate portions of the fractured long bone. The hole or incision is allowed or caused to close. An external adjustment device comprising at least one rotatable magnet is placed in proximity to the patient's skin. The external adjustment device is operated so that a magnetic field of the at least one rotatable magnet of the external adjustment device causes the rotatable permanent magnet of the variable length nail to rotate, causing either extension or retraction of the distraction shaft relative to the housing.

Abstract: A non-leaching mediator may include a polymer having a polymeric backbone, and a plurality of phenothiazine groups bonded to the polymeric backbone. The plurality of phenothiazine groups may include at least one of a phenothiazine group having the general formula (IV): and salts thereof, where n is about 9 and “R” represents the polymeric backbone to which the phenothiazine group is bonded, and a phenothiazine group having the general formula (V): and salts thereof, where n is about 9 and “R” represents the polymeric backbone to which the phenothiazine group is bonded.

Abstract: A non-leaching mediator may include a polymer comprising the general formula (VIII): and salts thereof, where R? is an organic group, m is 0 or 1, n is about 9, and x and y independently are an integer from 1 to 10,000.

Abstract: A method for treating a complex fracture with a variable length nail is provided. The nail is configured for at least 5 mm of axial length change in each direction. The method involves making a first hole or incision in the skin of the patient in proximity to a fractured long bone and at least partially clearing a canal through the center of the long bone. The variable length nail is inserted into the canal and securing a distraction shaft and a housing of the nail to separate portions of the fractured long bone. The hole or incision is allowed or caused to close. An external adjustment device comprising at least one rotatable magnet is placed in proximity to the patient's skin. The external adjustment device is operated so that a magnetic field of the at least one rotatable magnet of the external adjustment device causes the rotatable permanent magnet of the variable length nail to rotate, causing either extension or retraction of the distraction shaft relative to the housing.

Abstract: In one embodiment, a non-invasively adjustable spinal system for treatment of a subject having spondylolisthesis includes a first implantable actuator having at least one anchoring structure, the anchoring structure configured to facilitate securement of the first implantable actuator to a portion of the sacrum of the subject. The non-invasively adjustable spinal system can further include an adjustment element, configured to be coupled to the first implantable actuator, the adjustment element having an engagement structure configured to engage at least one transverse process of a lumbar vertebra of the subject. The non-invasively adjustable spinal system can further include a driving element, wherein remote activation of the driving element causes movement of the adjustment element in relation to the first implantable actuator.

Abstract: A method for treating a fracture with a variable length nail is provided. The nail is configured for at least 5 mm of axial length change in each direction. An incision is made in proximity to a fractured bone and canal is cleared through the center of the bone. The variable length nail is inserted into the canal and a distraction shaft and a housing are secured to separate portions of the fractured bone. The incision is allowed or caused to close. An external adjustment device with at least one rotatable magnet is placed in proximity to the patient's skin. The external adjustment device is operated so that a magnetic field of the at least one rotatable magnet of the external adjustment device causes the rotatable permanent magnet of the variable length nail to rotate, causing either extension or retraction of the distraction shaft relative to the housing.

Abstract: A non-leaching mediator may include a polymer comprising the general formula (VIII): and salts thereof, where R? is an organic group, m is 0 or 1, n is about 9, and x and y independently are an integer from 1 to 10,000.

Abstract: A non-leaching mediator may include a polymer having a polymeric backbone, and a plurality of phenothiazine groups bonded to the polymeric backbone. The plurality of phenothiazine groups may include at least one of a phenothiazine group having the general formula (IV): and salts thereof, where n is about 9 and “R” represents the polymeric backbone to which the phenothiazine group is bonded, and a phenothiazine group having the general formula (V): and salts thereof, where n is about 9 and “R” represents the polymeric backbone to which the phenothiazine group is bonded.