Abstract: IL-11Ra antibodies are disclosed. Also disclosed are compositions comprising the IL-11Ra antibodies, and methods using the IL-11Ra antibodies.

Abstract: IL-11 antibodies are disclosed. Also disclosed are compositions comprising the IL-11 antibodies, and methods using the IL-11 antibodies.

Abstract: A steering device for an aircraft landing gear leg including a main fitting has a steering collar for rotatably mounting on the outside of the main fitting; an actuator having an actuator body; and an actuator arm arranged to move between an extended position and retracted position with respect to the actuator body. The actuator arm is pivoted to the main fitting, and a bracket is pivoted to the main fitting; a second pivot location pivoted to the actuator body; and a third pivot location pivotally connected to one end of a steering arm. The steering arm is pivoted at its other end to the steering collar. Also, an aircraft landing gear with the steering device and aircraft having the landing gear.

Abstract: A method includes conveying a whipstock and a latch anchor into a parent wellbore, the latch anchor being attached to the whipstock at a releasable connection and the parent wellbore being lined with casing that includes a latch coupling. The latch anchor is secured to the latch coupling and the whipstock is then separated from the latch anchor at the releasable connection and thereby exposing a portion of the releasable connection. The whipstock is then removed from the parent wellbore and a completion deflector is subsequently conveyed into the parent wellbore in combination with lateral tubing (with or without a multilateral junction positioned thereabove), and the completion deflector is attached to the latch coupling at the releasable connection. The lateral tubing (with or without multilateral junction positioned thereabove) is then installed to correct depth.

Abstract: An aircraft wing having a fixed wing with a wing tip device. The wing tip device is movable between a flight configuration for use during flight, and a ground configuration for use during ground-based operations. The wing has a master flight control surface associated with the fixed wing and a slave flight control surface associated with the wing tip device. An interface between the master flight control surface and the slave flight control surface is arranged to provide a rigid connection between the master flight control surface and slave flight control surface when the wing tip device is in the flight configuration. Moving the master control surface about a control axis causes the slave control surface to be moved about the control axis. The interface is arranged to de-couple the slave and master control surfaces when the wing tip device is moved from the flight configuration into the ground configuration.

Abstract: Disclosed herein are systems, methods, and non-transitory computer-readable storage media for collecting call data, feeding call data to applications, and providing advanced call features.

Abstract: A satellite communications terminal for a ship may include an antenna with three antenna feeds operable at respective different frequencies, and communications circuitry coupled to the three antenna feeds and being configurable for a selected antenna feed. The terminal also includes a positioner to mount the antenna to the ship and point the antenna. A controller may select an antenna feed, configure the communications circuitry, and operate the positioner to point the antenna to a selected satellite all based upon the location of the ship and at least one selection rule. The selection rule may be a communications circuitry configuration rule and/or a service level agreement rule.

Abstract: A method for manufacture of a metal can body is described in which two or more stretching operations are used so as to reduce the thickness of the central part of a cup base, prior to drawing the cup sidewall and forming a can body. By using two or more stretching operations, it has been found possible to control the thickness of the base without significantly reducing pressure performance of the finished can. Alternative embodiments of apparatus comprising tooling for carrying out this method are also described.

Abstract: Disclosed herein are systems, methods, and non-transitory computer-readable storage media for collecting call data, feeding call data to applications, and providing advanced call features.

Abstract: An aircraft including a wing, the end of the wing having a wing tip device, wherein the wing tip device includes a moveable region that is rotatable, about an axis of rotation extending out of the plane of the wing tip device, between: (i) a high-altitude cruise configuration in which the moveable region extends downwardly below the wing; and (ii) a ground-operating configuration in which the moveable region extends rearwardly behind the wing such that the ground clearance of the wing tip device is increased.

Abstract: Aspects of the disclosure relate to the treatment, prevention or alleviation of conditions such as fibrosis in a subject. In some embodiments, the treatment, prevention or alleviation of fibrosis in a subject through the administration of an agent capable of inhibiting the action of Interleukin 11 (IL-11) is disclosed.

Abstract: A system and method for milling a casing in a wellbore wherein an upper milling portion of a milling system engages a track of a lower guide system of the milling system in order to orient the upper milling portion. The upper milling portion moves along a track from a first position to a second position, where the the upper milling portion is securedly affixed to the lower guide portion. A traveling guide arm is used to move the milling portion along a travel path. A piston on the traveling guide arm is disposed between first and second fluid chambers, with a throughbore in the piston forming a fluid path between the two chambers. An adjustable valve in the throughbore is controlled by a proximity sensor to alter the flow of fluid between the chambers. The sensor monitors the distance between a fixed and moving point of the milling system.

Abstract: A wing tip device for attachment to a wing tip of a powered aircraft including: a first mounting formation, a second mounting formation spaced apart in a spanwise direction relative to the first mounting formation, a third mounting formation spaced apart in a chordwise direction relative to the first and second mounting formations, wherein each of the first, second and third mounting formations are configured for attachment to at least one of a wing spar and a wing rib, and, at least one of the mounting formations is configured to permit movement of a portion of the wing tip device in the spanwise direction relative to a portion of the wing tip.

Abstract: Some methods enable a computer to receive location information from a device and determine a coverage region for the device. The device's coverage region is the area within range of a wireless signal coming from the device. The computer can determine that part of the device's coverage region covers part of a specified region and instruct the device to provide wireless access to a network associated with the first region.

Abstract: An aircraft including a wing (1) and a wing tip device (6). The wing tip device (6) is moveable between a flight configuration for use during flight and a ground configuration for use during ground-based operations. In the ground configuration the wing tip device is folded inwardly from the flight configuration such that the span of the aircraft is reduced. The wing tip device (6) is connected to the wing along a hinge axis (14) by spar beams (10 and 12) of the wing tip device, one of the beams being mounted for pivoting about a fixed axis and the other beam being mounted on a spherical bearing (15) to provide greater freedom of movement. Various actuator arrangements may be provided to pivot the wing tip device.

Abstract: A method of manufacturing a foldable aerodynamic structure, such as a wing, for an aircraft. The wing (1) including an inner region (1) and an outer region (3) rotatable relative to the inner region between a flight configuration and a ground configuration. The method includes designing the foldable aerodynamic structure by determining the location and orientation of an Euler axis of rotation (11) about which the outer region rotates to achieve the ground configuration and determining a cut plane (13), perpendicular to that Euler axis, separating the inner and outer regions; and iteratively repeating this process until a preferred cut plane (13) is obtained that satisfies at least one design criteria.

Abstract: Systems, methods, and non-transitory computer-readable storage media for gathering activity data describing a user's activities from one or more activity sensors and using the activity data to predict immune-response to the activity. Predicting immune-response can involve creating, personalizing, and refining immune-response prediction models based on demographic user data, activity data, blood sample data, personal genetic information.

Abstract: Systems, methods, and non-transitory computer-readable storage media for constructing a clinically-derived and personalized blood cell mobilization prediction models, enhancing the understanding of a blood tests by excluding the contemporary effect of the contemporary activity from the contemporary blood sample data, optimizing a vaccine by maximizing a concentration of a collection of immune cells which interact with the collection of antigens present in the vaccine can be prescribed, and enhancing the reliability of activity data by accounting for inconsistencies, gaps in data, etc. that is collected from telemetric devices.

Abstract: A wellbore isolation system is disclosed. The wellbore isolation system includes a junction positioned at an intersection of a first wellbore and a second wellbore, and a deflector disposed in the junction such that a path into the first leg of the junction is obstructed and engaged with the first leg of the junction to form a fluid and pressure tight seal. The junction includes a first leg extending downhole into the first wellbore, and a second leg extending downhole into the second wellbore. The deflector includes a channel extending axially through the deflector, and a degradable plug disposed in the channel and engaged with the channel to prevent fluid flow through the channel.

Abstract: A wellbore isolation system is disclosed. The wellbore isolation system includes a junction positioned at an intersection of a first wellbore and a second wellbore, and a deflector disposed in the junction such that a path into the first leg of the junction is obstructed and engaged with the first leg of the junction to form a fluid and pressure tight seal. The junction includes a first leg extending downhole into the first wellbore, and a second leg extending downhole into the second wellbore.