Abstract: The invention provides a compound of formula (0): or a pharmaceutically acceptable salt, N-oxide or tautomer thereof; wherein: n is 1 or 2; X is CH or N; Y is selected from CH and C—F; Z is selected from C—Rz and N; R1 is selected from: -(Alk1)t-Cyc1; wherein t is 0 or 1; Optionally substituted C1-6 acyclic hydrocarbon groups R2 is selected from hydrogen; halogen; and C1-8 hydrocarbon groups optionally substituted with one or more fluorine atoms; R3 is hydrogen or a group L1-R7; R4 is selected from hydrogen; methoxy; and optionally substituted C1-3 alkyl; and R4a is selected from hydrogen and a C1-3 alkyl group; wherein Rz, Alk1, Cyc1, L1 and R7 are defined herein; provided that the compound is other than 6-benzyl-3-{2-[(2-methylpyrimidin-4-yl)amino]pyridin-4-yl}-7,8-dihydro-1,6-naphthyridin-5(6H)-one and 3-{2-[(2-methylpyrimidin-4-yl)amino]pyridin-4-yl}-7,8-dihydro-1,6-naphthyridin-5(6H)-one and salts and tautomers thereof.

Abstract: A fuel injection system for an internal combustion engine is provided. The fuel injection system comprises a primary fuel injector, a sensor, at least one secondary fuel injector and a controller. The primary fuel injector is configured to inject fuel into an ignition chamber of the internal combustion engine. The sensor is coupled to the primary fuel injector, wherein the sensor is configured to sense a fuel pressure of the fuel being injected by the primary fuel injector throughout each injection cycle of the primary fuel injector. The at least one secondary fuel injector is configured to inject fuel into a respective ignition chamber of the internal combustion engine. The controller is configured to receive data indicative of the fuel pressure value throughout each injection cycle. The controller is configured to determine a fuel quantity drift parameter over a plurality of fuel injection cycles based on the data indicative of the fuel pressure value.

Abstract: In one embodiment, the present invention includes a method for securing tissue to bone, including drilling a bone hole into the bone; passing a filament through the tissue, the filament including a first end, a second end and a length therebetween, the second end having a loop; passing the first end of the filament through the loop of the filament; pulling on the first end of the filament such that the loop travels along the length of the filament and to the tissue; passing an anchor along the length of the filament, from the first end towards the loop and tissue; engaging the loop with a distal end of the anchor; positioning the distal end of the anchor, with the loop of the filament, into the bone hole; and securing the anchor in the bone.

Abstract: Generally discussed herein are devices, systems, and methods for adaptive authorization using a local route as a named location. A method can include defining a local route and a corresponding local route endpoint, associating a compute resource as a destination of the local route endpoint, defining an adaptive authorization policy that limits access to the compute resource to be through the local route endpoint, and enforcing access to the compute resource based on the defined adaptive authorization policy.

Abstract: A pluggable processor module includes a microprocessor package, a voltage regulator including a capacitor board, and contact pads that each include a first side in contact with the microprocessor package and a second side in contact with the capacitor board.

Abstract: Compositions are provided which include an effective amount of a compound selected from the group consisting of propanediol mononitrate and chloroform for the reduction of oxidative stress, the improvement of the immune system, the provision of healthy cartilage, as well as the alleviation of pain in ruminants.

Abstract: The present invention relates to the reduction of oxidative stress, the improvement of the system, the provision of healthy cartilage, as well as the alleviation of pain in ruminants.

Abstract: Methods are disclosed for the reduction of stress in ruminants in need thereof by administering propanediol mononitrate or chloroform or a composition which includes propanediol mononitrate or chloroform to a ruminant prior to experiencing stress, while experiencing stress and/or after having experienced stress.

Abstract: The present invention relates to the reduction of stress in ruminants in need thereof.

Abstract: A distance detector comprising: a laser transmitter and receiver for generating a laser beam to irradiate an object and to receive return light reflected in response from the object, an image detection system for generating an image of a view, the image detection system including an objective lens for collecting light from the view, an image sensor for receiving light collected by the objective lens and for generating the image therefrom, and a digital display for displaying the image such that the digital display displays a real-time image of the view, a laser beam indicium on the digital display or a laser beam indicium generator configured to display laser beam indicium on the digital display, wherein the laser beam indicium indicates a direction of the laser beam, and a range-finding system for determining the distance to an object irradiated by the laser beam using return light and for displaying distance.

Abstract: Various examples described herein are directed to systems and methods for securing data. A security system may receive a first record comprising a plurality of record fields, where the plurality of record fields includes a first record field and the first record field includes a first record field data. The security system may access a source setup record corresponding to the first record from a source setup table and determine that the source setup record comprises data referencing the first record field. The security system may access first token data corresponding to the first record field data and replace the first record field data at the first record field with the first token data. The security system may store the first token data at a token table and writing the first token data to the first record field to replace the first record field data.

Abstract: In one embodiment, the present invention includes a method for securing tissue to bone, including drilling a bone hole into the bone; passing a filament through the tissue, the filament including a first end, a second end and a length therebetween, the second end having a loop; passing the first end of the filament through the loop of the filament; pulling on the first end of the filament such that the loop travels along the length of the filament and to the tissue; passing an anchor along the length of the filament, from the first end towards the loop and tissue; engaging the loop with a distal end of the anchor; positioning the distal end of the anchor, with the loop of the filament, into the bone hole; and securing the anchor in the bone.

Abstract: In one embodiment, the present invention includes a method for securing tissue to bone, including drilling a bone hole into the bone; passing a filament through the tissue, the filament including a first end, a second end and a length therebetween, the second end having a loop; passing the first end of the filament through the loop of the filament; pulling on the first end of the filament such that the loop travels along the length of the filament and to the tissue; passing an anchor along the length of the filament, from the first end towards the loop and tissue; engaging the loop with a distal end of the anchor; positioning the distal end of the anchor, with the loop of the filament, into the bone hole; and securing the anchor in the bone.

Abstract: A vehicle seat having a vehicle seat base comprising a generally concave seat pan (4) and side plates (16) fixed to the seat pan for mounting the seat pan to the vehicle wherein the seat pan has, all relative to the direction of movement of the vehicle, a front face, a rear face, two lateral side faces and a bottom face, and wherein the side plates extend from the front towards the rear of the seat pan and are bonded to the lateral side faces along at least part of the length of each of the side plates. This produces a lightweight yet rigid seat base which enables a low block height.

Abstract: The present invention relates to the reduction of oxidative stress, the improvement of the system, the provision of healthy cartilage, as well as the alleviation of pain in ruminants.

Abstract: The present invention relates to the reduction of stress in ruminants in need thereof.

Abstract: A seat back for a vehicle seat comprising a panel (4) and a frame structure (6, 8, 10), the frame structure being formed of two metal tubes (6, 8) having first ends joined together by a crossmember ((10) and second ends joined together by a first member to form a tapering framework which is wide at the bottom of the seat back and narrow at the top of the seat back, wherein there is no cross-bracing of the frame between the top and bottom of the seat back. The framework is mounted to the panel such that in use the second ends are positioned near the lower portion of the seat back and the first ends are positioned towards the upper portion of the seat back.

Abstract: Various examples described herein are directed to systems and methods for securing data. A security system may receive a first record comprising a plurality of record fields, where the plurality of record fields includes a first record field and the first record field includes a first record field data. The security system may access a source setup record corresponding to the first record from a source setup table and determine that the source setup record comprises data referencing the first record field. The security system may access first token data corresponding to the first record field data and replace the first record field data at the first record field with the first token data. The security system may store the first token data at a token table and writing the first token data to the first record field to replace the first record field data.

Abstract: Pitting corrosion of stainless steel occurs in solutions of organic acid, such as tartaric acid, in an electrolyte solution with methanol. However, methanolic solutions containing at least one organic halide and at least one organic hydroxyl-acid and some water provide reduced pitting corrosion of stainless steel. The organic hydroxyacid may be a hydroxy acid containing 2 to 10 carbon atoms with at least one hydroxyl group and at least one carboxylic acid group, in a non-limiting example, glycolic acid. The pH of the methanolic solution may range from about 3.5 to about 8.

Abstract: A seat back for a vehicle seat comprising a panel (4) and a frame structure (6, 8, 10), the frame structure being formed of two metal tubes (6, 8) having first ends joined together by a crossmember ((10) and second ends joined together by a first member to form a tapering framework which is wide at the bottom of the seat back and narrow at the top of the seat back, wherein there is no cross-bracing of the frame between the top and bottom of the seat back. The framework is mounted to the panel such that in use the second ends are positioned near the lower portion of the seat back and the first ends are positioned towards the upper portion of the seat back.