Abstract: An embodiment method of building a battery state of health (SOH) estimation model includes applying, by an optimization server, an error of a model voltage, an error of a measured voltage, a capacity, or a resistance of a battery mounted in a vehicle as an objective function and performing error minimization processing to derive optimal parameters of the battery.

Abstract: A flow guiding device in an immersion-cooled chassis of a server comprises at least one deflector located above a chip on a mainboard in the chassis, each deflector comprises a first end for mounting to the mainboard above the chip and a second end inclined away from the mainboard. The first end is immersed in coolant, the second end is higher than the first end; the deflector further comprises a hollow part including multiple through holes for interrupting upward movement vapor bubbles generated by the hot chip, which reduces probability of the vapor bubbles escaping from the coolant liquid and the chassis. A liquid-cooled chassis having the flow guiding device is also disclosed.

Abstract: A curable composition is capable of forming a thick film having excellent curing characteristics even at a relatively low temperature and is capable of securing an excellent level of thermal conductivity as well as a desired level of appropriate adhesion force while having fast curing characteristics. A battery pack to which the curable composition is applied, and a device comprising the battery pack are also provided.

Abstract: A substrate assembly includes a first substrate, a second substrate and a bonding member. The first substrate includes a first surface-modified region having a functionality different from that of a remainder region of the first substrate. The second substrate includes a second surface-modified region connected to the first surface-modified region through a physical interaction and having a functionality different from that of a remainder region of the second substrate. The first and second substrates cooperatively define a space therebetween. The bonding member is disposed within said space to bond said first and second substrates together. A method for bonding substrates is also disclosed.

Abstract: A speed generation method for simulating riding is provided. A computer device (20) retrieves a riding weight and road condition information, selects one of a plurality of preset gear ratios (30) as a selected gear ratio, retrieves a wheel rotating speed of a bicycle (4), and determines a simulated speed in a simulating riding service based on the selected gear ratio, a tire parameter, and the rotating speed.

Abstract: The present invention provides compositions and methods of inhibiting tyrosine phosphorylation. In one aspect, a composition comprising a low-dosage tyrosine kinase inhibitor, where the low-dosage tyrosine kinase inhibitor decreases tyrosine phosphorylation, is provided. In another aspect, a method for treating cardiovascular disease or condition associated with a RASopathy having aberrant protein tyrosine phosphorylation is described. Methods for treating congenital heart disease associated with Noonan or Noonan syndrome with multiple lentigines and decreasing aberrant levels of Protein Zero-Related (PZR) tyrosyl phosphorylation are also described.

Abstract: Disclosed herein is an asymmetric rolling joint device of a surgical instrument which increases traction force by asymmetrically forming rolling contact surfaces of joint links facing each other. The asymmetric rolling joint device includes: a first joint link part which forms a joint of the surgical instrument; and a second joint link part coming into rolling contact with the first joint link part, wherein rolling contact surfaces where the first joint link part and the second joint link part come into rolling contact with each other are formed asymmetrically so as to increase traction force more than rolling contact surfaces which are formed symmetrically.

Abstract: The present invention provides compositions and methods of inhibiting tyrosine phosphorylation. In one aspect, a composition comprising a low-dosage tyrosine kinase inhibitor, where the low-dosage tyrosine kinase inhibitor decreases tyrosine phosphorylation, is provided. In another aspect, a method for treating cardiovascular disease or condition associated with a RASopathy having aberrant protein tyrosine phosphorylation is described. Methods for treating congenital heart disease associated with Noonan or Noonan syndrome with multiple lentigines and decreasing aberrant levels of Protein Zero-Related (PZR) tyrosyl phosphorylation are also described.

Abstract: A flexible drive manipulator according to an example embodiment may include a proximal portion, a plurality of joint portions drivably connected from an end of the proximal portion with respect to a longitudinal axis, a distal portion connected to an end of the plurality of joint portions, a pair of drive wires passing through the plurality of joint portions in parallel along the longitudinal axis, the pair of drive wires configured to drive the plurality of joint portions in a rotational direction of rotation with respect to a transverse axis perpendicular to the longitudinal axis, and a fixing wire passing through the plurality of joint portions in a shape of converging along the longitudinal axis, the fixing wire configured to adjust rigidity of the plurality of joint portions.

Abstract: An environmentally friendly method of coating copper nanowires to reduce oxidation and/or increase electrical/thermal conductivity of the copper nanowires. In one embodiment, a method for coating copper nanowires includes preparing a first solution including a dipolar aprotic organic compound, adding copper nanowires to the first solution under stirring while maintaining the first solution at a pre-determined temperature, preparing a second solution including an oxidation resistant metal, coating the copper nanowires in the oxidation resistant metal by adding the second solution to the first solution under stirring and while maintaining the first solution at the pre-determined temperature.

Abstract: A substrate assembly includes a first substrate, a second substrate and a bonding member. The first substrate includes a first surface-modified region having a functionality different from that of a remainder region of the first substrate. The second substrate includes a second surface-modified region connected to the first surface-modified region through a physical interaction and having a functionality different from that of a remainder region of the second substrate. The first and second substrates cooperatively define a space therebetween. The bonding member is disposed within said space to bond said first and second substrates together. A method for bonding substrates is also disclosed.

Abstract: A flexible drive manipulator according to an example embodiment may include a proximal portion, a plurality of joint portions drivably connected from an end of the proximal portion with respect to a longitudinal axis, a distal portion connected to an end of the plurality of joint portions, a pair of drive wires passing through the plurality of joint portions in parallel along the longitudinal axis, the pair of drive wires configured to drive the plurality of joint portions in a rotational direction of rotation with respect to a transverse axis perpendicular to the longitudinal axis, and a fixing wire passing through the plurality of joint portions in a shape of converging along the longitudinal axis, the fixing wire configured to adjust rigidity of the plurality of joint portions.

Abstract: A substrate assembly includes a first substrate, a second substrate and a bonding member. The first substrate includes a first surface-modified region having a functionality different from that of a remainder region of the first substrate. The second substrate includes a second surface-modified region connected to the first surface-modified region through a physical interaction and having a functionality different from that of a remainder region of the second substrate. The first and second substrates cooperatively define a space therebetween. The bonding member is disposed within said space to bond said first and second substrates together. A method for bonding substrates is also disclosed.

Abstract: A substrate assembly and a method of bonding substrates are disclosed. The method includes steps of: providing two substrate; subjecting a connecting surface of each of the substrates to surface-modifying treatment to form surface-modified region respectively on each of the connecting surfaces; contacting the substrates in such a manner that the substrates are connected with each other through a physical interaction between the surface-modified regions; and laser irradiating and melting a portion of each of the connecting surfaces to form a respective bonding region, and solidifying the melted bonding regions of the substrates to bond the substrates together.

Abstract: A frame for a bicycle includes a front frame, a rear frame, an upper linkage, and a shock absorber. The rear frame is pivoted to the front frame at a main pivot axis. The upper linkage is pivoted to the front frame at a first pivot axis and is pivoted to the rear frame at a second pivot axis. The shock absorber is pivoted to the upper linkage at a third pivot axis and is pivoted to the front frame. When a compression ratio of the shock absorber is in a range between 0% and 60%, a distance variation between a pivot location of the rear frame at the second pivot axis and a pivot location of the rear frame at the main pivot axis reaches a maximum value thereof.

Abstract: A resistive memory apparatus including a memory cell array and a voltage selector circuit is provided. The memory cell array includes a plurality of memory cells. The voltage selector circuit is coupled to the memory cell array. The voltage selector circuit performs a voltage applying operation on the memory cells via a plurality of different signal transmission paths. Each of the signal transmission paths passes one of the memory cells. IR drops of two of the signal transmission paths are substantially identical, and signal transmission directions thereof are different. In addition, an operating method of a resistive memory apparatus is also provided.

Abstract: An intermediate material of a thermoplastic prepreg for a fuel cell separation plate comprises a hydrophobic thermoplastic resin film and a fiber base. The hydrophobic thermoplastic resin film has a degree of crystallization of 1 to 20%, a thickness of 3 to 50 ?m, and (iii) a content of an electroconductive material of 1 to 20 wt. %. The film is laminated on at least one surface of the fiber base. The thermoplastic prepreg for a fuel cell separation plate is manufactured by pressurizing the thermoplastic prepreg intermediate material at a temperature higher than the melting point of the hydrophobic thermoplastic resin film. A fuel cell separation membrane manufactured using the thermoplastic prepreg intermediate material and thermoplastic prepreg is thin and light-weight, and have a good durability.

Abstract: A method of manufacturing a microfluidic chip includes: providing an upper mold having multiple upper ribs extending along a second direction, and a lower mold having multiple lower ribs extending along a first direction different from the second direction; forming a forming material in a filling space defined by the upper and lower molds to provide a channeled plate having multiple upper microfluidic channels complementary in shape to the upper ribs, lower microfluidic channels complementary in shape to the lower ribs, and multiple thin film valves formed at intersections where the upper microfluidic channels intersect the lower microfluidic channels; separating the upper and lower molds; and covering the lower and upper microfluidic channels.

Abstract: A frame for bicycle includes a front frame, a rear frame, a shock absorber and an upper linkage. The upper linkage is pivoted to the front frame at a first axis, pivoted to the rear frame at a second axis, and pivoted to the shock absorber at a third axis. The rear frame has a pair of chain stays and a connection part, the connection part has a pair of side portions and a bridge portion, the pair of side portions are connected to the pair of chain stays respectively, the bridge portion connects the pair of side portions, and the rear frame is pivoted to the front frame at a fourth axis through the pair of side portions or through the pair of chain stays.

Abstract: An electrochemical biosensor includes a substrate, a plurality of layered active metal parts, a plurality of layered electrodes, a reaction confinement layer, an electrochemical reactive layer and a cover piece. The substrate is formed with through holes each of which is defined by an interior wall surface and penetrates top and bottom surfaces. Each of the layered active metal parts is formed at least upon a respective one of the interior wall surfaces. The layered electrodes are formed on the layered active metal parts. The reaction confinement layer confines a reactor space over a region where the through holes are formed. The electrochemical reactive layer is disposed in the reactor space and is electrically coupled to the layered electrodes.