Abstract: An intraocular micro-display (IOMD) system includes an auxiliary head unit. The auxiliary head unit includes a frame for mounting to a head of a user, a scene camera module mounted in or on the frame in a forward-facing orientation, a gaze tracking module disposed in or on the frame and configured to monitor an eye of the user, and an auxiliary controller. The auxiliary controller includes for: acquiring a scene image with the scene camera module, determining a gazing direction of the eye based upon gaze direction data from the gaze tracking module, identifying a sub-portion of the scene image based upon the gazing direction, and wirelessly relaying the sub-portion of the scene image to an IOMD implant within the eye for displaying to a retina of the eye.

Abstract: An intraocular micro-display (IOMD) system includes an auxiliary head unit. The auxiliary head unit includes a frame for mounting to a head of a user, a scene camera module mounted in or on the frame in a forward-facing orientation, a gaze tracking module disposed in or on the frame and configured to monitor an eye of the user, and an auxiliary controller. The auxiliary controller includes for: acquiring a scene image with the scene camera module, determining a gazing direction of the eye based upon gaze direction data from the gaze tracking module, identifying a sub-portion of the scene image based upon the gazing direction, and wirelessly relaying the sub-portion of the scene image to an IOMD implant within the eye for displaying to a retina of the eye.

Abstract: A processor signals a display to show a target. Optics is positioned in an optical path taken by the target, as shown by the display, from the display to the eye of a user. The optics is configured to change accommodation by the eye and has adjustable focal length that enables the user to see the target with changing acuity. The processor then obtains an indication that the eye of the user is focused on the target. In response, the processor signals an alignment mechanism to align a sensor in the device to the eye of the user. After signaling the alignment mechanism to align the sensor to the eye of the user, the processor obtains sensor data, produced by the sensor, which measures a property of the eye. Other aspects are also described and claimed.

Abstract: Systems, devices, and methods for determining an intraocular pressure (IOP) of an eye are provided. A system may include a pump configured to generate a puff of air and a nozzle configured to direct the puff of air along a first axis toward the eye. The system may further include a light source distal of the nozzle and directed to emit a beam of light toward the first linear optical sensor along a second axis transverse to the first axis. A first portion of the beam of light illuminates a lateral surface of the eye and a second portion of the beam of light passes in front of the eye. The system may further include a first linear optical sensor disposed distal of the nozzle and configured to receive the second portion of the beam of light.

Abstract: Systems and methods are provided for determining a likelihood that a drop released from a bottle will land in an eye of a user. Each of an eye of a user and a tip of a bottle and illuminated and imaged to provide at least one image. An orientation of the bottle is determined via an inertial measurement unit, and a likelihood that a drop released from the bottle will land in the eye of the user is determined from the determined orientation and the at least one image.

Abstract: Virtual reality, VR, headset-based and augmented reality, AR, headset-based electronic systems that can be used to perform cover/uncover tests. The systems may improve the sensitivity, consistency, and ease of application of the cover/uncover test. Other aspects are also described.

Abstract: An eye drop monitoring device for monitoring gravity-driven placement of an eye drop into an eye of a patient includes a light source configured to selectively direct light toward at least one of the eye and the eye drop. The light is backscattered by at least one of the eye and the eye drop. A light detector is configured to detect the backscattered light from at least one of the eye and the eye drop and responsively produce at least one backscatter signal. An accelerometer is configured to determine a spatial position of the device and responsively produce a device position signal. A processing unit is configured to receive the at least one backscatter signal and the device position signal and responsively produce a drop-on-target signal indicative of a likelihood that the eye drop fell into a predetermined position with respect to the eye.

Abstract: A stand-alone appliance can detect a user's face/eyes and provide violet light to the user. The appliance can include a fixture mounted on a platform and at least one motor to move the platform. A directed light source, coupled to a processor, can emit a light signal directed to an adjustable focal point. A camera, coupled to the processor, can detect the user and provide an image of the user's face to the processor. The processor can signal the motor to orient the platform to bring an eye into a center of a frame and adjust the focal point. A distance sensor, coupled to the processor, can estimate a distance between the fixture and the eye to ensure that an appropriate optical energy density is applied to the user. The camera, the directed light source, and/or the distance sensor can be embedded in the fixture.

Abstract: An intraocular micro-display (IOMD) system includes an auxiliary head unit. The auxiliary head unit includes a frame for mounting to a head of a user, a scene camera module mounted in or on the frame in a forward-facing orientation, a gaze tracking module disposed in or on the frame and configured to monitor an eye of the user, and an auxiliary controller. The auxiliary controller includes for: acquiring a scene image with the scene camera module, determining a gazing direction of the eye based upon gaze direction data from the gaze tracking module, identifying a sub-portion of the scene image based upon the gazing direction, and wirelessly relaying the sub-portion of the scene image to an IOMD implant within the eye for displaying to a retina of the eye.

Abstract: A system for fluorescence activated cell sorting includes at least two excitation lasers having different orientations relative to an objective such that light from the at least two lasers passes through the objective and intersects a fluidic channel at different positions within an interrogation region. The fluidic channel directs a flow of a plurality of fluorescently labeled particles through the interrogation region. The system further includes at least one detector and at least one optical element that directs light emitted from the plurality of fluorescently labeled particles and transmitted through the objective to the at least one detector. The system may further include optics for generating and detecting side and forward scattered light. Methods for operating example systems to collect fluorescent, side scattered and forward scattered light from a plurality of particles are also described herein.

Abstract: A method for performing corneal topography. Image data produced by an eye tracker camera that is integrated into an eye tracking virtual reality headset is processed, to detect eye position and movement during ophthalmic examination of the wearer of the headset. The image data produced by the eye tracker camera is also processed to detect a spacing of spots within, or a shape of, a Purkinje image that is in the image data. A topography map of the wearer's cornea is produced based on the detected spacing or the detected shape of the Purkinje image and based on the detected eye position and movement. Other aspects are also described and claimed.

Abstract: A headset includes a first display, a second display that is smaller than the first display and has lower resolution than the first display, and a dichroic filter positioned to pass visible light from the first display toward the eye and reflect visible light from the second display toward the eye. Pixel data control circuitry is coupled to darken the first display while simultaneously activating the second display to display a pattern for testing visual acuity, responsive to a first visual acuity test selection. Other aspects are also described and claimed.

Abstract: Systems, apparatuses, and methods for detecting carious lesions are described herein. In an example, the systems in an optical interrogator including a single-pixel photodetector responsive to short-wave infrared light and operatively coupled to a controller. In an example the optical interrogator includes a light engine for emitting light, a scanning mirror assembly and a single-pixel photodetector. In an example, the methods include causing the light engine to emit light having wavelengths in a range of about 900 nm to about 1,700 nm; selectively directing the light over different portions of a tooth with a scanning mirror assembly to provide scattered light; and correlating scattered light signals generated by the single-pixel photodetector in response to the scattered light with the portion of the tooth.

Abstract: An intraocular pressure sensing element along with implant microelectronic circuitry to be configured to be implanted into an eye of a user. The microelectronic circuitry is conductively coupled to the intraocular pressure sensing element to produce measured pressure data. A microscopic light emitting diode, LED, that is also implanted into the eye, is driven with the measured pressure data thereby optically transmitting the measured pressure data for communication with outside of the eye. A photovoltaic element that is also implanted into the eye supplies energy to operate the implant microelectronic circuitry and the microscopic LED. Other aspects are also described and claimed.

Abstract: An implant that is to be implanted inside the eye of a person contains a laser projection scanning subsystem that is configured to “paint” an image of the scene that is before the person, on the retina. The image of the scene may be acquired by a digital camera that is attached to a head unit that may be worn by the person, and then transmitted to the implant. Other aspects are also described and claimed.

Abstract: Systems and methods for biometric authentication in ophthalmic devices are provided. In one embodiment, a system includes: an ophthalmic diagnostic device configured to obtain diagnostic measurements of a patient's eye, the patient's eye including an iris and a cornea; an imaging device configured to capture an image of the iris; an optical sensor integrated with the imaging module and configured to detect a position of the iris with respect to the optical sensor; and a computing device in communication with the ophthalmic diagnostic device, imaging device, and the optical sensor. The computing device may be configured to: determine, based on the image of the iris and the position of the iris, whether the iris matches a known patient's iris; and perform a diagnostic measurement of the patient's eye based on the determining.

Abstract: High-throughput hyperspectral imaging systems are provided. According to an aspect of the invention, a system includes an excitation light source; an objective that is configured to image excitation light onto the sample, such that the excitation light causes the sample to emit fluorescence light; a channel separator that is configured to separate the fluorescence light into a plurality of spatially dispersed spectral channels; and a sensor. The excitation light source includes a light source and a plurality of lenslet arrays. Each of the lenslet arrays is configured to receive light from the light source and to generate a pattern of light, and the patterns of light generated by the lenslet arrays are combined to form the excitation light. The objective is configured to simultaneously image each of the patterns of light to form a plurality of parallel lines or an array of circular spots at different depths of the sample.

Abstract: Devices, systems, and associated methods for detecting drops dispensed by a dropper are provided. For example, a drop detection device may include a light source and a light detector configured to be coupled to a drop dispenser such that the light source and light detector are disposed proximal of a distal dispensing tip of the drop dispenser. The light detector may be configured to receive a reflected portion of a beam of light from the light source, which is reflected by a drop dispensed through the dispensing tip of the drop dispenser. In some embodiments, a processing circuit is configured to analyze a signal provided by the light detector to detect the dispensed drop.

Abstract: An intraocular pressure (IOP) measurement system. An optical pressure sensor is implantable in the cornea of an eye, wherein the sensor has a sealed cavity that changes shape as a function of IOP of the eye. An optical transmitter that is outside of the eye emits an incident optical beam. A receiver that is also outside of the eye produces an output signal in response to receiving reflections of the incident beam from the sensor. A processor is configured to estimate the IOP of the eye based on processing the output signal of the receiver. Other aspects are also described and claimed.

Abstract: An intraocular pressure (IOP) measurement system. An ultrasound pressure sensor is implantable in an eye, wherein the sensor has a sealed cavity that changes shape as a function of IOP of the eye. An ultrasound transmitter emits an incident ultrasound beam. A receiver produces an output signal in response to receiving a reflected ultrasound beam. A spectrometer is configured to estimate the IOP of the eye based on processing the output signal of the receiver. Other aspects are also described and claimed.