Abstract: Organodifluorine synthons, in conjunction with three-component diastereoselective Anion Relay Chemistry (ARC), permit ready access to diverse difluoromethylene scaffolds. Initiated via [1,2]-addition of an organolithium reagent to a ?-difluoromethylene silyl aldehyde, an alkoxide intermediate is formed, which is capable of undergoing a [1,4]-Brook rearrangement to generate a stabilized ?-difluoromethylene carbanion, which upon electrophile capture, affords a three-component adduct. This three-component synthetic tactic represents an important one-pot divergent strategy for the construction of diverse organodifluorine containing compounds.

Abstract: Disclosed herein are compositions and methods for manufacturing composite paper-based sorbents configured for durability, and high surface area exposure to air. Composite paper-based sorbents can comprise fibers (e.g. natural and/or synthetic fibers), anion exchange resins, and additives. Composite paper-based sorbents can be configured for durability when used in various forming processes, e.g., corrugation, and when used under a variety of conditions, for example, in high and low humidity environments.

Abstract: Methods and systems are described for assessing a computer network using a graph model. In some instances, the methods comprise: receiving data from at least one data stream of a plurality of data streams, wherein the plurality of data streams comprise computer network data provided by one or more data brokers, and wherein the data received from different data streams of the plurality comprise different data formats; converting the data received from the at least one data stream to a common data format comprising a node or an edge; updating a graph model comprising a plurality of nodes and edges stored within a graph database according to the node or edge of the converted data; and providing a user of the computer network with a visualization of a status of the computer network.

Abstract: A forceps includes an end effector assembly having a stop and a plurality of overmold teeth within at least one jaw member. One (or both) of the jaw members is moveable relative to the other between a spaced-apart position and an approximated position for grasping tissue therebetween. One (or both) of the jaw members includes a stop molded within an insulative housing, and an insulator plate with the overmold teeth formed from plastic. The overmold teeth extend through openings within a sealing plate and protrude past the tissue sealing surface of the sealing plate. The stop primarily controls the gap distance between opposing jaw members by bearing most of an applied load and the overmold teeth assist in controlling the gap distance by bearing the remaining applied load.

Abstract: A non-nematicidal composition comprises at least one glucan and/or at least one fucan which act individually or synergistically with mannitol to reduce losses in crop yield and marketable grade caused by the infestation of growth media with plant pathogenic nematodes, to levels equivalent to those achieved with commercial nematicides, but without posing a risk to the ecosystem or user. In some cases the composition comprises at least one glucan, at least one fucan and at least one mannitol which may be in a weight/weight ratio of approximately 1:2:3 of at least one glucan:at least one fucan:at least one mannitol or between approximately 1:1:1 to 1:1:3 of at least one glucan:at least one fucan:at least one mannitol.

Abstract: A system coupled to a non-human subject comprising communication circuitry configured to communicatively couple to a medical device coupled to the subject and a remote computing system, the medical device configured to monitor physiological data of the non-human subject and the remote computing system configured to store historical data for the non-human subject; processing circuitry; and a memory comprising instructions that, when executed by the processing circuitry, cause the processing circuitry to: receive the monitored physiological data from the medical device; determine whether the medical device indicates that the monitored physiological data is in satisfaction of at least one condition triggering an upload of at least a portion of the monitored physiological data; and in response to the determination, generate, for communication to the remote computing system, output data comprising the at least a portion of the monitored physiological data.

Abstract: Systems and methods are provided for controlling infrared radiation (IR) sources of a sauna including tuning IR wavelength-ranges and radiated power-levels of IR sources, and directing IR to locations on a user's body. In one illustrative embodiment, a sauna may be provided having adjustable IR emitters to emit IR at any wavelength resulting in a desirable radiation treatment for the sauna user. In another illustrative embodiment, a method is provided for tuning IR emitters in a sauna.

Abstract: The present disclosure relates to compositions, such as siRNA molecules and FN3 domains conjugated to the same, as well as methods of making and using the molecules.

Abstract: A forceps includes an end effector assembly having a stop and a plurality of overmold teeth within at least one jaw member. One (or both) of the jaw members is moveable relative to the other between a spaced-apart position and an approximated position for grasping tissue therebetween. One (or both) of the jaw members includes a stop molded within an insulative housing, and an insulator plate with the overmold teeth formed from plastic. The overmold teeth extend through openings within a sealing plate and protrude past the tissue sealing surface of the sealing plate. The stop primarily controls the gap distance between opposing jaw members by bearing most of an applied load and the overmold teeth assist in controlling the gap distance by bearing the remaining applied load.

Abstract: The present disclosure relates to polypeptides, such as fibronectin type III (FN3) domains that can bind CD71, their conjugates, isolated nucleotides encoding the molecules, vectors, host-cells, as well as methods of making and using the same.

Abstract: A system incentivizing greenhouse gas sequestration is provided having a greenhouse gas receiving station, a greenhouse gas storage system having a sequestration potential, a signal indicative of the sequestration potential of the greenhouse gas storage system received by said greenhouse gas receiving station, the greenhouse gas receiving station determining a storage cost based on a greenhouse gas and the signal indicative of the sequestration potential, the greenhouse gas receiving station determining a renewable energy credit based on the signal indicative of the sequestration potential of the greenhouse gas storage system.

Abstract: A system incentivizing green energy usage is provided having a charging station, an electricity source electrically connected to said charging station, a signal indicative of the sustainability of the electricity source received by said charging station, a mobile electric device receiving electrical charge from said charging station, a signal indicative of electrical charge drawn from the electrical charging station, a signal indicative of usage data for the mobile electric device, the charging station determining pricing based on at least one of the signal indicative of the sustainability of the electricity source, the signal indicative of the electrical charge drawn and the signal indicative of usage data.

Abstract: Systems and methods are provided for controlling infrared radiation (IR) sources of a sauna including tuning IR wavelength-ranges and radiated power-levels of IR sources, and directing IR to locations on a user's body. In one illustrative embodiment, a sauna may be provided having adjustable IR emitters to emit IR at any wavelength resulting in a desirable radiation treatment for the sauna user. In another illustrative embodiment, a method is provided for tuning IR emitters in a sauna.

Abstract: A forceps is provided and includes a housing having a shaft. An end effector assembly operatively connects to a distal end of the shaft and includes a pair of first and second jaw members. One or both of the first and second jaw members is movable relative to the other jaw member from a clamping position to an open position. A resilient member operably couples to at least one of the first and second jaw members. The resilient member is configured to bias the first and second jaw members in the clamping position and provide a closure force on tissue disposed therebetween.

Abstract: A method for synthesizing an energetic compound via direct assembly. The energetic compound being characterized by a local structure that features four crystallographically unique copper atoms bound by nine unique azide molecules and one tetrazole molecule with potassium ions to form a salt.

Abstract: A programmable and universal video platform enabling digital ads from ad sales teams, online digital exchanges, demand side platforms or other digital video advertising aggregators, to be inserted into linear television cable programming feeds. Content programmers distribute a programming schedule file for each linear programming feed. This data is then combined in the traffic and billing system with the advertising insertion orders from the various sales channels to create a local ad insertion schedule file. This schedule file includes a planned ad spot, but a time-based approach to ad insertion allows the schedule file to be modified such that the planned ad spot can be replaced with a replacement ad selected using the VAST digital ad selection protocol. Detection of the standard cue message in the programming feed triggers insertion of the replacement ad from the modified schedule file.

Abstract: A computer implanted method of updating a user joining a group after a user-relevant topic has been discussed, the method includes, with a processor operatively-coupled to a memory: identifying the user joining group after a first topic has been discussed in the current session of the group; and determining interest of the user in the first topic, wherein if the first topic is determined to be of interest to the user, providing an automated summary of the first topic to the user.

Abstract: A forceps is provided and includes a housing having a shaft. An end effector assembly operatively connects to a distal end of the shaft and includes a pair of first and second jaw members. One or both of the first and second jaw members is movable relative to the other jaw member from a clamping position to an open position. A resilient member operably couples to at least one of the first and second jaw members. The resilient member is configured to bias the first and second jaw members in the clamping position and provide a closure force on tissue disposed therebetween.

Abstract: An assembly system includes a fixture configured to support a structure including at least one component to receive a malleable material, and a bladder system coupled to the fixture. The bladder system includes a hollowed frame having sidewalls that support a bladder disposed therein. The hollowed frame has an opening that exposes an outer portion of the bladder and is configured to guide the exposed outer portion externally from the hollowed frame toward a targeted area of the structure. In response to inflating the bladder, the outer portion of the bladder extends through the opening and applies a force against the at least one component so as to form a design feature element from the malleable material.

Abstract: Methods for synthesizing in situ two energetic compounds. A first energetic compound being characterized by a first local structure that features metal centers bound by 1-tetrazole, 4-cyanobenzene and azide molecules, while a second energetic compound is characterized by a second local structure that features metal centers bound by 1-methyltetrazole and azide molecules. Both energetic compounds may further be characterized as crystalline coordination polymers (CPs).