Patents by Inventor T. Wang

T. Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tissue electroperforation for enhanced drug delivery and diagnostic sampling
    Publication number: 20020010414
    Abstract: The present invention relates to a method and a device for transporting a molecule through a mammalian barrier membrane of at least one layer of cells comprising the steps of: ablating said membrane with an electric current from an array of treatment electrodes; and utilizing a driving force to move said molecule through said perforated membrane.
    Type: Application
    Filed: February 28, 2001
    Publication date: January 24, 2002
    Inventors: Anthony F. Coston, Ying Sun, Ralph W. Oakeson, Stephen J. Wisniewski, Jonas C.T. Wang
  • Method of manufacturing liposomes
    Publication number: 20020001613
    Abstract: The present invention relates to a method of making a liposome, said method comprising the steps of: (a) mixing a lipophilic phase and a hydrophilic phase, said lipophilic phase comprising an amphiphilic bilayer-forming substance; and (b) applying a cavitational sheer force to said mixture to form said liposome; wherein said cavitational force is created by contacting said mixture with a member that vibrates at an ultrasonic frequency.
    Type: Application
    Filed: February 9, 2001
    Publication date: January 3, 2002
    Inventors: Susan Niemiec, Glenn A. Nystrand, Jonas C.T. Wang
  • NOVEL TOPICAL COMPOSITIONS
    Publication number: 20010055597
    Abstract: Skin care compositions comprising an oil-in-water emulsion base containing retinoids and possessing good physical and chemical stability
    Type: Application
    Filed: February 27, 1997
    Publication date: December 27, 2001
    Inventors: JUE-CHEN LIU, JONAS C. T. WANG, MOHAMMED YUSEF, NORIHIRO YAMAMOTO, SATOSHI KAZAMA, CHRISTOPHER R. STAHL, JEAN P. HOLLAND, KAMRAN MATHER, MARGARET A. ALELES, SACHIO HAMADA, CURTIS A. COLE, STEPHEN J. WISNIEWSKI
  • Process for the enzymatic resolution of lactams
    Publication number: 20010055798
    Abstract: A method of separating enantiomeric lactam esters. The lactam esters are contacted with a biocatalyst, such as an enzyme or a microorganism, in a solution wherein only one enantiomer is selectively hydrolyzed to give the optically active isomer of the corresponding acid. The hydrolysis product is then separated from the unreacted lactam esters. The enzyme is then recycled for reuse in the next enzymatic resolution. The undesired isomer is also racemized and reused in the next enzymatic resolution.
    Type: Application
    Filed: June 6, 2001
    Publication date: December 27, 2001
    Applicant: G.D. Searle & Co.
    Inventors: Donald W. Hansen, Mahima Trivedi, Rolando E. Gapud, John S. Ng, Alok K. Awasthi, Ping T. Wang
  • Processes for preparation of 9, 11-epoxy steroids and intermediates useful therein
    Patent number: 6331622
    Abstract: A process for the formation of an epoxy compound comprising contacting a substrate compound having an olefinic double bond with a peroxide compound in the presence of a peroxide activator, said peroxide activator corresponding to the formula: where Ro is a substituent having an electron withdrawing strength not less than that of monochloromethyl.
    Type: Grant
    Filed: February 8, 1999
    Date of Patent: December 18, 2001
    Assignee: G.D. Searle & Co.
    Inventors: John S. Ng, Ping T. Wang, Julio A. Baez, Chin Liu, Dennis K. Anderson, Jon P. Lawson, Bernhard Erb, Joseph Wieczorek, Gennaro Mucciariello, Fortunato Vanzanella, Sastry A. Kunda, Leo J. Letendre, Mark J. Pozzo, Yuen-Lung L. Sing, Edward E. Yonan
  • Method for isolating and characterizing nucleic acid sequences
    Patent number: 6312913
    Abstract: The present invention provides methods for determining nucleic acid sequences based on known sequences adjacent to the unknown sequences, and reagents for using such methods.
    Type: Grant
    Filed: July 21, 2000
    Date of Patent: November 6, 2001
    Assignee: Incyte Genomics, Inc.
    Inventors: Jonathan T. Wang, Glenn K. Fu, Walter H. Lee, Laura L. Stuve
  • Topical delivery systems for active agents
    Patent number: 6284234
    Abstract: This invention relates to a method for enhancing the transmembrane penetration of benefit agents using a certain non-ionic lipid/surfactant-containing formulation as an enhancing agent, and the compositions used therein. Various active agents, such as anti-dandruff agents, hair growth agents, hair inhibitor agents, anti-acne agents, anti-aging agents, depilatory agents, and depigmentation agents, may be effectively delivered into the skin, hair follicles and sebaceous glands using the compositions of the present invention.
    Type: Grant
    Filed: July 23, 1999
    Date of Patent: September 4, 2001
    Assignee: Johnson & Johnson Consumer Companies, Inc.
    Inventors: Susan M. Niemiec, Jonas C. T. Wang, Stephen J. Wisniewski, Kurt S. Stenn, Gwang Wei Lu
  • Digital fluid delivery and aspiration apparatus with mechanical de-amplifier
    Patent number: 6277096
    Abstract: A digital fluid delivery and aspiration apparatus with a mechanical de-amplifier for the delivery or removal of discrete volumes of fluidic material from a surgical site. The apparatus has a syringe with a plunger designed to be powered by a pneumatic air supply system. A ratcheting mechanism attached to a pneumatic piston by a mechanical linkage causes the plunger of the syringe to inject discrete doses of the fluidic material into the surgical site or remove discrete amounts of fluidic material from the surgical site. The mechanical linkage increases the force provided to the plunger by the movement of the piston and also de-amplifies the movement of the piston into a lesser movement of the plunger.
    Type: Grant
    Filed: June 13, 2000
    Date of Patent: August 21, 2001
    Assignee: Medical Instrument Development Laboratories, Inc.
    Inventors: Julian M. Cortella, Carl C.T. Wang
  • Process for the enzymatic resolution of lactams
    Patent number: 6277626
    Abstract: A method of separating enantiomeric lactam esters. The lactam esters are contacted with a biocatalyst, such as an enzyme or a microorganism, in a solution wherein only one enantiomer is selectively hydrolyzed to give the optically active isomer of the corresponding acid. The hydrolysis product is then separated from the unreacted lactam esters. The enzyme is then recycled for reuse in the next enzymatic resolution. The undesired isomer is also racemized and reused in the next enzymatic resolution.
    Type: Grant
    Filed: February 16, 1999
    Date of Patent: August 21, 2001
    Assignee: G.D. Searle & Co.
    Inventors: Donald W. Hansen, Jr., Mahima Trivedi, Rolando E. Gapud, John S. Ng, Alok K. Awasthi, Ping T. Wang
  • VIDEOCONFERENCING ARRANGEMENT USING A CAMERA DISPLAY SCREEN
    Publication number: 20010012050
    Abstract: A videoconferencing system uses a modular terminal that includes a conventional video camera or digital still camera coupled to the input port of the videocommunicator, such as a set top box. The camera includes a video input port and a display screen, and the videocommunicator is coupled to the video input port of the camera, whereby videoconference images are displayed on the camera display screen.
    Type: Application
    Filed: February 11, 1998
    Publication date: August 9, 2001
    Applicant: NETERGY NETWORKS, INC.
    Inventors: SAMUEL T. WANG, DOUGLAS JOHN BAILEY, JOSEPH L. PARKINSON
  • Keto-Substituted Steroid Compounds
    Patent number: 6258946
    Abstract: Multiple novel reaction schemes, novel process steps and novel intermediates are provided for the synthesis of epoxymexrenone, useful as a diuretic, and other compounds of Formula I wherein the variables are as defined by the specification.
    Type: Grant
    Filed: May 30, 2000
    Date of Patent: July 10, 2001
    Assignee: G. D. Searle & Co.
    Inventors: John S. Ng, Ping T. Wang, Julio A. Baez, Chin Liu, Dennis K. Anderson, Jon P. Lawson, Bernhard Erb, Joseph Wieczorek, Gennaro Mucciariello, Fortunato Vanzanella, Sastry A. Kunda, Leo J. Letendre, Mark J. Pozzo, Yuen-Lung L. Sing, Edward E. Yonan
  • Star-branched rubber thermoplastic elastomer vulcanizates
    Patent number: 6255389
    Abstract: The present invention relates to a curable composition comprising a thermoplastic polyolefin resin and a curable star-branched rubber, a thermoplastic elastomeric vulcanizate obtainable therefrom by dynamically vulcanizing said curable composition in the presence of a suitable curative and shaped articles comprising said vulcanizate.
    Type: Grant
    Filed: August 27, 1998
    Date of Patent: July 3, 2001
    Assignee: Advanced Elastomer Systems, L.P.
    Inventors: Trazollah Ouhadi, Donald S. T. Wang, Paul A. Schacht
  • Acidified composition for topical treatment of nail and skin conditions
    Patent number: 6231875
    Abstract: This invention relates to a method for topical treatment of human nail and skin diseases, including fungal infections, bacterial infections, and psoriatic infections. In addition, this invention relates to a method of treating the general condition of human nails including their strength, rate of growth and appearance. More particularly, the invention relates to an acidified composition and methods of using said composition. Still further the invention relates to an acidified lacquer useful in treating human nails and skin.
    Type: Grant
    Filed: March 9, 1999
    Date of Patent: May 15, 2001
    Assignee: Johnson & Johnson Consumer Companies, Inc.
    Inventors: Ying Sun, Jue-Chen Liu, Elizabeth Kimbleton, Jonas C. T. Wang
  • Method and apparatus for preparation of chiral beta amino acids using penicilln G acylase
    Patent number: 6214609
    Abstract: A method for preparing a chiral beta amino acid or its corresponding esters which comprises contacting a racemic beta amino acid, an acyl donor and Penicillin G acylase enzyme under conditions appropriate to stereoselectively acylate one enantiomer of the racemic beta amino acid to its corresponding N-acylated derivative whereby the opposite enantiomer of the beta amino acid is retained in enantiomerically enriched form.
    Type: Grant
    Filed: May 1, 1998
    Date of Patent: April 10, 2001
    Assignee: Monsanto Company
    Inventors: Bryan H. Landis, John S. Ng, Ravindra S. Topgi, Edward E. Yonan, Ping T. Wang
  • Topical compositions
    Patent number: 6193956
    Abstract: The present invention relates to a two-part container containing an outer container and an inner container for use in containing skin care compositions.
    Type: Grant
    Filed: April 6, 1999
    Date of Patent: February 27, 2001
    Assignee: Johnson & Johnson Consumer Companies, Inc.
    Inventors: Jue-Chen Liu, Jonas C. T. Wang, Mohammed Yusuf, Norihiro Yamamoto, Satoshi Kazama, Christopher R. Stahl, Jean P. Holland, Kamran Mather, Margaret A. Aleles, Sachio Hamada, Curtis A. Cole
  • Processes for preparation of 9,11-epoxy steroids and intermediates useful therein
    Patent number: 6180780
    Abstract: Multiple reaction schemes, process steps and intermediates are provided for the synthesis of epoxymexrenone, useful as a diuretic, and other compounds of Formula I wherein the variables are as defined by the specification.
    Type: Grant
    Filed: February 9, 1999
    Date of Patent: January 30, 2001
    Assignee: G.D. Searle & Co.
    Inventors: John S. Ng, Ping T. Wang, Julio A. Baez, Chin Liu, Dennis K. Anderson, Jon P. Lawson, Bernhard Erb, Joseph Wieczorek, Gennaro Mucciariello, Fortunato Vanzanella, Sastry A. Kunda, Leo J. Letendre, Mark J. Pozzo, Yuen-Lung L. Sing, Edward E. Yonan
  • Organosilane cured butyl rubber/polypropylene TPV
    Patent number: 6147160
    Abstract: An improved process for the preparation of thermoplastic elastomers by hydrosilylation crosslinking of a butyl rubber component, in which a platinum containing hydrosilylation catalyst is used. The butyl rubber component includes a copolymer of at least isobutylene and an aromatic divinyl compound such as divinylbenzene. The copolymer of at least isobutylene and divinylbenzene is significantly easier to crosslink into a substantially insoluble rubber in a thermoplastic vulcanizate than isobutylene copolymers with only unsaturated repeating units from conjugated dienes. A crosslinked rubber component is obtained in the thermoplastic elastomer composition.
    Type: Grant
    Filed: November 30, 1998
    Date of Patent: November 14, 2000
    Assignee: Advanced Elastomer Systems, L.P.
    Inventors: Donald S. T. Wang, Robert E. Medsker
  • System and method for preventing an air embolism in a surgical procedure
    Patent number: 6106497
    Abstract: A system and method is provided for preventing the development of an air embolism in an animal during and after a cardiovascular surgical procedure. Also provided is a device that can accurately control the pressure and/or flow of gas into the heart cavity and related blood vessels.
    Type: Grant
    Filed: January 29, 1998
    Date of Patent: August 22, 2000
    Assignee: Medical Instrument Development Laboratories
    Inventor: Carl C. T. Wang
  • Method and apparatus for loading a wafer into a test machine
    Patent number: 6104184
    Abstract: The present invention discloses a removable wafer mounting tray for positioning a wafer in a microscope by utilizing a tray body that is generally constructed in a disk shape and has a recess in its top surface for receiving a wafer to be tested. The wafer mounting tray further includes a handle that extends outwardly from the tray adapted for gripping by a machine arm or by a human hand for placement of the wafer mounting tray into a test machine. The novel wafer mounting tray shelters and protects a wafer during transit to and from a test machine such that wafer breakage or scratching problems can be substantially reduced.
    Type: Grant
    Filed: November 17, 1997
    Date of Patent: August 15, 2000
    Assignee: Taiwan Semiconductor Manufacturing Company, Ltd.
    Inventors: K. C. Huang, S. T. Wang
  • Digital fluid delivery and aspiration apparatus with mechanical de-amplifier
    Patent number: 6102895
    Abstract: A digital fluid delivery and aspiration apparatus with a mechanical de-amplifier for the delivery or removal of discrete volumes of fluidic material from a surgical site. The apparatus has a syringe with a plunger designed to be powered by a pneumatic air supply system. A ratcheting mechanism attached to a pneumatic piston by a mechanical linkage causes the plunger of the syringe to inject discrete doses of the fluidic material into the surgical site or remove discrete amounts of fluidic material from the surgical site. The mechanical linkage increases the force provided to the plunger by the movement of the piston and also de-amplifies the movement of the piston into a lesser movement of the plunger.
    Type: Grant
    Filed: September 30, 1997
    Date of Patent: August 15, 2000
    Inventors: Julian M. Cortella, Carl C. T. Wang