Abstract: The present specification discloses a composition for preventing hair loss or promoting hair growth comprising, as an active ingredient, extracellular follicles derived from lactic acid bacteria, and a method for preparing the extracellular follicles derived from lactic acid bacteria. The composition has an effect of preventing and prohibiting hair from falling off from the scalp or becoming thin or tapered. In addition, the composition has an effect of implementing a hair growth function for generating new hair, or a function for promoting the hair growth, as well as a function of promoting a delay from an anagen to a catagen phase of a hair cycle and a function of growing the existing hair healthy.

Abstract: The present disclosure relates to a composition for promoting adipocyte differentiation or adiponectin production, including a trimethoxy phenyl compound, an isomer thereof, a pharmaceutically acceptable salt thereof, a hydrate thereof or a solvate thereof as an effective ingredient. A composition according to the present specification promotes adipocyte differentiation or adiponectin production, thereby exhibiting the effect of making the skin plump or increasing skin elasticity. Hence, the composition of the present specification can find various applications as a pharmaceutical composition or cosmetic composition in the field such as that concerning skin damage.

Abstract: The present specification discloses a composition for caring for skin damage caused by fine dust, wherein the composition includes a fermented tea extract as an active ingredient and adjusts the expression level of at least one selected from the following group of genes which are present in skin cells and have expression levels that are affected by fine dust to normal levels, said group consisting of: IL-1B (NM_000576), IL-36G (NM_019618), S100A7 (NM_002963), LCE3D (NM_032563), PTGS2 (NM_000963) and XDH (NM_000379). Damage to skin cells can be cared for by using the composition for caring for skin damage caused by fine dust to return gene expression levels, which change due to fine dust, to normal levels.

Abstract: Disclosed in the present specification is a composition comprising a Prunus mume flower extract as an effective ingredient for treating fine dust-caused skin damage, wherein the expression of IL-36G (NM 019618), which is a gene having an expression level affected by fine dust in skin cells, is regulated to a novel level. By using the composition for treating fine dust-caused skin damage, gene expression changed by fine dust can return to a normal level to treat skin cell damage.

Abstract: A skin external composition containing 1,2,3,4,6-penta-O-galloyl-?-D-glucose (hereinafter referred to as “PGG”) and its use to improve moisture balance of skin are disclosed. The skin external composition, due to containing PGG, stimulates the formation of filaggrin in keratinocytes, increases loricrin and involucrin expression, thereby stimulating the formation of a normal keratin layer, and as a result, can strengthen the skin barrier function to provide an excellent skin moisturization improving effect. Thus, the composition is effective in improving moisture balance of skin. A method for moisturizing the skin using the composition is also disclosed.

Abstract: Disclosed is a composition including a Hibiscus syriacus extract as an effective ingredient for treating fine dust-caused skin damage, wherein the expression of at least one selected from the group consisting of IL-36G (NM_019618), PTGS2 (NM_000963), XDH (NM_000379) and S100A7 (NM_002963), which are all genes having the expression levels affected by fine dust in skin cells, is regulated to a normal level and for inhibiting an antibacterial peptide, wherein the expression of the antibacterial peptide S100A7 (NM_002963) is regulated to a normal level. By using the composition for treating fine dust-caused skin damage and the composition for inhibiting an antibacterial peptide, gene expression changed by fine dust can return to a normal level to treat skin cell damage and the increased expression of the antibacterial peptide due to various causes can return to normal level.

Abstract: Disclosed in the present specification are: a composition for preventing hair loss or promoting hair growth, containing ginseng-derived exosome-like vesicles; and a method for preparing the composition. The ginseng-derived exosome-like vesicles can have a diameter of 20-500 nm and can be isolated from ginseng root. The composition contains ginseng-derived exosome-like vesicles as active ingredients, thereby having an effect of inducing hair growth by activating dermal papilla cells (DPCs).

Abstract: Disclosed are: a lightening composition comprising ginseng-derived exosome-like vesicles; and a method for producing the ginseng-derived exosome-like vesicles. The ginseng-derived exosome-like vesicles may have a diameter of between 20 and 500 nm, and may be isolated from ginseng root. Because the composition comprises the ginseng-derived exosome-like vesicles as an active ingredient, said composition is effective in preventing, improving or treating skin pigmentation conditions such as liver spots, freckles, lentigo, birth marks and melanoma by effectively suppressing the production of melanin.

Abstract: Disclosed is a novel use of a composition comprising as an active ingredient a Scutellaria alpina extract. A composition according to the present description shows hair follicle cell proliferation or hair growth effect by means of comprising a Scutellaria alpina extract. Therefore, due to said effect, the Scutellaria alpina extract has hair loss prevention or hair growth stimulation effect.

Abstract: Unlike a conventional method for evaluating a degree of ultraviolet protection through visual evaluation, the disclosed method for measuring a sunlight protection function can accurately and objectively measure and determine a degree of sunlight protection by measuring a change due to a material to be measured with respect to an expression amount of skin tissue antimicrobial peptides (AMPs) in skin cells, which decrease from exposure to sunlight, and/or a generation amount of S-nitrosylated protein. Additionally, the disclosed measurement method can determine whether blue/violet light of wavelengths of 400-500 nm, which induces the most skin damage among visible rays, is blocked and provide a more specified sunlight protection effect evaluation result. Moreover, by using the disclosed measurement method, a degree of sunlight protection can be indexed, and a sunlight protection composition for protecting normal skin from the blue/violet light can be provided.

Abstract: The present invention relates to novel melanocytes and melanoblasts. In addition, the present invention relates to a novel method for producing melanocytes and melanoblasts. Specifically, provided is novel melanocytes of which gene expression, melanin content, and tyrosinase activity are different from those of conventional melanocytes. Even more specifically, provided is novel melanoblasts of which the gene expression, the melanin content the tyrosinase activity, and the protein expression are different from those of conventional melanocytes. Additionally, provided is a novel method for producing melanocytes or melanoblasts by culturing keratinocytes.

Abstract: Disclosed in the present specification are a method for preparing senescent melanocytes, senescent cells prepared by the preparation method and a method for screening a senescence-alleviating or skin whitening material by using the senescent cells. The cells can be used for studying a cell senescence phenomenon and a pigmentation mechanism, which are caused by the accumulation of UV ray stimulation. Particularly, the cells are useful since a material having both senescence-alleviating and skin whitening effects can be screened.

Abstract: The present invention relates to a cosmetic composition which contains jade powder so as to block blue light in the visible spectrum. The composition, containing jade powder as an active ingredient, for blocking blue light is capable of specifically reflecting and thus blocking light in the blue light spectrum, which has been difficult to block, thereby protecting the skin.

Abstract: According to an embodiment, a method of producing artificial skin includes mixing fibroblasts and collagen to form a dermis simulating layer, applying keratinocytes on the dermis simulating layer and culturing the same, culturing the dermis simulating layer in a first medium that is a keratinocyte medium, and culturing the dermis simulating layer that is cultured in the first medium in a second medium including a DMEM medium and a F12 medium.

Abstract: The present specification is intended to develop a new substance which exhibits a skin whitening effect and to apply the new substance to a composition for skin whitening, provides a new composition for skin whitening and a new kit for skin whitening which contain TNFSF14 protein and a polynucleotide encoding the TNFSF14 protein and a method of using the same, and thus can contribute to the market expansion and industry development related to the skin whitening field.

Abstract: Disclosed are: a lightening composition comprising ginseng-derived exosome-like vesicles; and a method for producing the ginseng-derived exosome-like vesicles. The ginseng-derived exosome-like vesicles may have a diameter of between 20 and 500 nm, and may be isolated from ginseng root. Because the composition comprises the ginseng-derived exosome-like vesicles as an active ingredient, said composition is effective in preventing, improving or treating skin pigmentation conditions such as liver spots, freckles, lentigo, birth marks and melanoma by effectively suppressing the production of melanin.

Abstract: The present specification discloses a composition for preventing hair loss or promoting hair growth comprising, as an active ingredient, extracellular follicles derived from lactic acid bacteria, and a method for preparing the extracellular follicles derived from lactic acid bacteria. The composition has an effect of preventing and prohibiting hair from falling off from the scalp or becoming thin or tapered. In addition, the composition has an effect of implementing a hair growth function for generating new hair, or a function for promoting the hair growth, as well as a function of promoting a delay from an anagen to a catagen phase of a hair cycle and a function of growing the existing hair healthy.

Abstract: Disclosed in the present specification are: a composition for preventing hair loss or promoting hair growth, containing ginseng-derived exosome-like vesicles; and a method for preparing the composition. The ginseng-derived exosome-like vesicles can have a diameter of 20-500 nm and can be isolated from ginseng root. The composition contains ginseng-derived exosome-like vesicles as active ingredients, thereby having an effect of inducing hair growth by activating dermal papilla cells (DPCs).

Abstract: The present invention relates to a composition containing a chemokine, particularly, an interferon-inducible T-cell alpha chemoattractant (ITACT) which can decrease the gene expression of a factor related to melanin pigment production in melanocytes, thereby exhibiting a skin whitening effect.

Abstract: Disclosed is a novel use of a composition comprising as an active ingredient an Artemisia umbelliformis extract. A composition according to the present description shows hair follicle cell proliferation or hair growth effect by means of comprising an Artemisia umbelliformis extract. Therefore, due to said effect, the Artemisia umbelliformis extract has hair loss prevention or hair growth stimulation effect.