Abstract: The present invention relates to novel melanocytes and melanoblasts. In addition, the present invention relates to a novel method for producing melanocytes and melanoblasts. Specifically, provided is novel melanocytes of which gene expression, melanin content, and tyrosinase activity are different from those of conventional melanocytes. Even more specifically, provided is novel melanoblasts of which the gene expression, the melanin content the tyrosinase activity, and the protein expression are different from those of conventional melanocytes. Additionally, provided is a novel method for producing melanocytes or melanoblasts by culturing keratinocytes.

Abstract: Provided in the present invention are adult stem cells derived from human skin dermis, and a method for isolating same. Further provided in the present invention are osteoblastic cells and adipocytes differentiated from the adult stem cells derived from human skin dermis, and a differentiation method therefor. Further provided in the present invention is a composition for osteogenesis or lipogenesis containing the stem cells, osteoblastic cells, or adipocytes. The isolation method of the present invention enables the adult stem cells derived from human skin dermis to be obtained in an easy and simple manner at a high yield rate. Genes and growth factors which are specifically expressed in the adult stem cells derived from human skin dermis isolated using the method can be separated, identified, and used later.

Abstract: Disclosed is a composition for a whitening effect or for the prevention of gray hair, which includes antisense nucleic acid molecules of SEQ ID NO: 2, wherein the composition has an miRNA of SEQ ID NO: 1 or a base sequence complementary thereto. Also disclosed is a method for controlling chromogenesis in test materials and for screening for expression control materials of chromogenic genes. The composition and the screening method can be used for the whitening effect or for the prevention of gray hair.

Abstract: Disclosed is a method for manufacturing fermented tea having superior flavor using Bacillus sp. strains isolated from Korean traditional fermented foods.

Abstract: The present invention relates to a method for calculating a thermal protection factor, wherein the method comprises the steps of: applying heat to a first area coated with a thermal protection material, and a second area not coated with the thermal protection material; measuring the respective saturation temperatures of the first area and second area; calculating a first energy by dividing the energy corresponding to the heat applied to the first area by the saturation temperature of the first area; calculating a second energy by dividing the energy corresponding to the heat applied to the second area by the saturation temperature of the second area; and calculating the thermal protection factor of a thermal protection material by dividing the first energy by the second energy or dividing the difference between the first energy and the second energy by the first energy.

Abstract: The present invention relates to a method for screening for materials for promoting the differentiation of skin cells, comprising: a step of treating skin cells with a test material; and a step of checking the relative degree of the expression of the DUOX 1 gene in the skin cells treated with the test material in the previous step. The present invention also relates to a kit for screening for materials for promoting the differentiation of skin cells, comprising a device for checking the relative degree of expression of the DUOX 1 gene in skin cells. The present invention also relates to a composition which contains, as an active ingredient, a material for increasing the expression of the DUOX 1 gene to promote the differentiation of skin cells, moisturize the skin, improve skin barrier function, or alleviate or treat symptoms of atopic dermatitis.

Abstract: Provided is a cosmetic composition for improving skin elasticity containing Phyllanthus urinaria extract and a polymersome in which an anti-aging peptide is stabilized as active ingredients. The cosmetic composition of the present disclosure is efficacious in improving skin wrinkles, restoring skin elasticity and increasing skin water content, and thus is effective for improving skin elasticity.

Abstract: The present invention relates to an agent for controlling Bcl-2 expression comprising ginsenoside F1 (20-O-?-D-glucopyranosyl-20(S)-protopanaxatriol) represented by the following formula 1 as an active component.

Abstract: Disclosed is a method for manufacturing fermented tea having superior flavor using Bacillus sp. strains isolated from Korean traditional fermented foods.

Abstract: Disclosed herein is the use of a composition, containing isoflavone-containing soybean extract, L-carnitine, caffeine and arginine as active ingredients, for the treatment of obesity and diabetes. The disclosed composition contains isoflavone-containing soybean extract, carnitine, caffeine and arginine in the form of a mixture, and thus shows not only the effect of promoting lipolysis and fat burning, but also anti-obesity and anti-diabetic effects by increasing the expressions of adiponectin and Glut4 genes to restore insulin sensitivity.

Abstract: The present invention relates to a skin-care composition containing ginsenoside F1 and EGCG. More particularly, the present invention relates to an inhibitor of UV-induced apoptosis in epidermal cells showing an excellent skin-care effect by the synergistic interaction of the said ginsenoside F1 and EGCG even at low concentrations, and to a method for inhibiting apoptosis in epidermal cells.

Abstract: The present invention relates to an agent for controlling Bcl-2 expression comprising ginsenoside F1 (20-O-?-D-glucopyranosyl-20(S)-protopanaxatriol) represented by the following formula 1 as an active component.

Abstract: The present invention relates to a composition containing genistein that accelerates the expression of the Carnitine Palmitoyl Transferase-1 (CPT-1) for improving or treating obesity. More particularly, the composition of the present invention comprises genistein that accelerates the expression of the CPT-1, an important enzyme for the lipolysis of fatty acid, and comprises carnitine that transports fatty acid into mitochondria and accelerates oxidation of fat in the oxidation process of fatty acid.

Abstract: The present invention relates to an agent for controlling Bcl-2 expression comprising ginsenoside F1 (20-O-?-D-glucopyranosyl-20(S)-protopanaxatriol) represented by the following formula 1 as an active component.

Abstract: The downregulation of PRP 19 (precursor RNA processing 19) protein expression results in effectively reducing the expression of SCD1 (stearyl CoA desaturase-1), the key lipogenic enzyme, and its down-stream triacylglycerol synthesis enzymes, DGAT-1 (diacyglycerol acyltransferase-1) and GPAT (glycerol-phosphate acyltransferase), as well as the intracellular content of neutral lipids, the major target for treating obesity.

Abstract: The present invention relates to a composition containing genistein that accelerates the expression of the Carnitine Palmitoyl Transferase-1 (CPT-1) for improving or treating obesity. More particularly, the composition of the present invention comprises genistein that accelerates the expression of the CPT-1, an important enzyme for the lipolysis of fatty acid, and comprises carnitine that transports fatty acid into mitochondria and accelerates oxidation of fat in the oxidation process of fatty acid.