Abstract: [Problem] An object of the present invention is to provide an anti-human IL-23R antibody having excellent activity and/or cross-reactivity compared to conventional IL-23R antibodies, and means for using the antibody to prevent or treat various diseases such as ophthalmic disease, inflammatory bowel disease, or psoriasis in which human IL-23R is involved in pathogenesis. [Means for Solution] An anti-human IL-23R antibody comprising a heavy-chain variable region consisting of the amino acid sequence shown by SEQ ID NO:10 or 14 and a light-chain variable region consisting of the amino acid sequence shown by SEQ ID NO:6 or 18.

Abstract: In a control device for an internal combustion engine including an air-fuel ratio sensor that includes a catalyst layer that covers an exhaust gas-side electrode, an oxygen storage capacity of the catalyst layer is acquired based on a sensor output of the air-fuel ratio sensor. The sensor output is corrected if the oxygen storage capacity is higher than a predetermined value and the sensor output is in a predetermined range in the vicinity of the theoretical air-fuel ratio. Preferably, the oxygen storage capacity is calculated by integrating the product of a deviation amount ?A/F of the sensor output with respect to the theoretical air-fuel ratio and a dwell time thereof. A correction period in which a correction operation is performed is set based on the oxygen storage capacity.

Abstract: [Problem] An object of the present invention is to provide an anti-human IL-23R antibody having excellent activity and/or cross-reactivity compared to conventional IL-23R antibodies, and means for using the antibody to prevent or treat various diseases in which human IL-23R is involved in pathogenesis. [Means for Solution] An anti-human IL-23R antibody comprising a heavy-chain variable region consisting of the amino acid sequence shown by SEQ ID NO:5, 9, 13, 17, 21, 25 or 29 and a light-chain variable region consisting of the amino acid sequence shown by SEQ ID NO:7, 11, 15, 19, 23, 27 or 31.

Abstract: An oxygen amount (an oxygen storage amount OSA) stored by metal cerium during a storage cycle is obtained based on an output value of an A/F sensor in a time period immediately before an exhaust air-fuel ratio (a downstream side A/F) detected by the A/F sensor shifts to a lean region, and degradation relating to OSC of the three-way catalyst is detected. In the storage cycle, a target air-fuel ratio is set so that an air-fuel ratio of exhaust emission flowing into an S/C changes from rich to lean. Therefore, the downstream side A/F shifts from stoichiometry to the lean region at a time after reaching stoichiometry. When the three-way catalyst degrades, the downstream side A/F shifts to the lean region from stoichiometry at a time. Therefore, the calculated oxygen storage amount OSA becomes extremely smaller as compared with that at a normal time.

Abstract: A control apparatus controls an automatic stop of an engine mounted on a vehicle so as to automatically stop the engine if a predetermined stop condition is satisfied, the stop condition including a condition that a running speed of the vehicle is a prescribed speed or less. The control apparatus includes a prediction unit and a prohibition unit. The prediction unit predicts whether or not the next automatic stop time of the engine is less than a prescribed time capable of obtaining a fuel saving benefit based on a history of a vehicle stop time or an automatic stop time of the engine. The prohibition unit prohibits the next automatic stop of the engine if the prediction unit predicts that the next automatic stop time of the engine is less than the prescribed time.

Abstract: A correction device for an air/fuel ratio sensor in the present invention, the sensor issuing an output according to an air/fuel ratio and installed on the downstream from catalyst of the exhaust passage, has air/fuel ratio control means for controlling an air/fuel ratio of an exhaust gas on the upstream side from a catalyst to switch between a rich air/fuel ratio which is richer and a lean air/fuel ratio which is leaner than a stoichiometric air/fuel ratio. Moreover, correction means for correcting an output of the sensor in accordance with a difference between the output of the sensor during a predetermined period during air/fuel ratio control by the air/fuel ratio control means, and a reference output corresponding to a stoichiometric air/fuel ratio, is provided.

Abstract: There is provided a heating controlling device having: a receiving section receiving heating instructions for plural heaters; and a controller that, when the receiving section receives a heating instruction to heat another heater while two or more heaters other than the heater for which the heating instruction is received are heating, stops heating of the heaters that are heating, after a first predetermined time period elapses from the control to stop heating, starts heating of the heater for which the heating instruction is received, and each time a number of second predetermined time periods elapses from the control to start heating, restarts heating, on the basis of predetermined priority rankings, of the heaters that were controlled to stop heating.

Abstract: A sensor characteristic correction device is configured to detect a characteristic of a first sensor arranged upstream of a catalyst 6 in an exhaust passage 4 of an internal combustion engine 2, and a characteristic of a second sensor that is an air-fuel sensor 12 arranged downstream of the catalyst 6, to calculate a first air-fuel ratio based on the characteristic of the first sensor, and calculates a second air-fuel ratio based on the characteristic of the second sensor, to detect, when the catalyst 6 is in an inactive state after start-up of the internal combustion engine 2, a difference between the first characteristic and the second characteristic or a difference between the first air-fuel ratio and the second air-fuel ratio, and to correct the responsiveness of the first or the second sensor in accordance with the difference.

Abstract: In a control device for an internal combustion engine including an air-fuel ratio sensor that includes a catalyst layer that covers an exhaust gas-side electrode, an oxygen storage capacity of the catalyst layer is acquired based on a sensor output of the air-fuel ratio sensor. The sensor output is corrected if the oxygen storage capacity is higher than a predetermined value and the sensor output is in a predetermined range in the vicinity of the theoretical air-fuel ratio. Preferably, the oxygen storage capacity is calculated by integrating the product of a deviation amount ?A/F of the sensor output with respect to the theoretical air-fuel ratio and a dwell time thereof. A correction period in which a correction operation is performed is set based on the oxygen storage capacity.

Abstract: In this invention, an EMF oxygen sensor is subjected to an activation process applying unidirectional voltage between an atmosphere electrode and an exhaust electrode thereof. A control device controlling the oxygen sensor in which a voltage was applied with the atmosphere electrode being positive, additionally applies unidirectional voltage between the electrodes to make the atmosphere electrode positive, for example, when the oxygen sensor was used under an environment in which the air-fuel ratio of the internal combustion engine was rich relative to the theoretical air-fuel ratio. Conversely, A control device controlling the oxygen sensor in which a voltage was applied to make the atmosphere electrode negative, additionally applies unidirectional voltage between the electrodes to make the atmosphere electrode negative, for example, when the oxygen sensor was used under an environment in which the air-fuel ratio was lean relative to the theoretical air-fuel ratio.

Abstract: An air-fuel ratio imbalance detection apparatus includes an air-fuel ratio sensor that is arranged in an exhaust passage of an internal combustion engine and that includes an electrode and a diffusion layer provided on the electrode; an estimating unit configured to estimate or detect an output variation amount that is an amount of variation in an output of the air-fuel ratio sensor due to an influence of a pressure pulsation of exhaust gas from the internal combustion engine; and a determination unit configured to determine whether there is an air-fuel ratio imbalance among cylinders of the internal combustion engine, on the basis of the output variation amount and a determination value based on the output of the air-fuel ratio sensor.

Abstract: Disclosed is a path-continuity check method for checking continuity of a path. The method includes transmitting a check frame by a node device on an upstream side and receiving the check frame by a node device on a downstream side; registering, by the node device on the upstream side, path information of the check frame and a transmission port in a transmission learning table together with a downstream learning number as a table number of a reception learning table of the node device on the downstream side in which the path information is registered; and setting, by the node device on the upstream side, plural of the downstream learning numbers registered in the transmission learning table in one aggregation check frame as table number ON information items and transmitting, by the node device on the upstream side, the one aggregation check frame to the node device on the downstream side.

Abstract: The present invention relates to a gas concentration detection apparatus for detecting the concentration of a specific gas component in an exhaust gas emitted from an engine, and forms a deterioration judgment about the gas concentration detection apparatus accurately and immediately. After excess oxygen is discharged by an oxygen pump cell 2, a NOx concentration detection apparatus, judges whether a NOx sensor 1 is activated. If the NOx sensor 1 is not activated yet, an output increase rate Vu(t) of the NOx sensor cell output N during an increase process of the NOx sensor cell output N is acquired. The present invention judges whether the output increase rate Vu(t) is lower than a predetermined reference value Vth1. If the obtained judgment result indicates that Vu(t)<Vth1, the NOx sensor cell 4 is deteriorated.

Abstract: Fuel reforming catalysts 28 generate a hydrogen-containing reformed gas when they come into contact with exhaust gas that contains a reforming fuel. Upstream and downstream air-fuel ratio sensors 58, 60 are respectively installed upstream and downstream of the fuel reforming catalysts 28. The upstream air-fuel ratio sensor 58 outputs a upstream sensor signal in accordance with oxygen concentration. The downstream air-fuel ratio sensor 60 outputs a downstream sensor signal in accordance with oxygen concentration and hydrogen concentration by using zirconia's oxygen detection capability and a change of a diffusion layer's hydrogen-concentration-dependent oxygen detection capability. An ECU 50 detects the hydrogen concentration without being affected by the oxygen concentration through the use of the upstream sensor signal in which only the oxygen concentration is reflected and the downstream sensor signal in which the oxygen concentration and hydrogen concentration are reflected.

Abstract: It is an object of the present invention to provide a gas concentration detection apparatus that is capable of forming an accurate activity judgment when a gas concentration detection cell begins to detect gas concentration with high accuracy. When warm-up begins at time t0 in a NOx concentration detection apparatus that achieves NOx concentration detection with a NOx sensor cell after excess oxygen is discharged by an oxygen pump cell, a NOx sensor cell output begins to rise at time t1. Subsequently, at time t2, an oxygen pump cell output begins to rise. An inflection point appearing in the NOx sensor cell output is then located. At time t5 at which the inflection point appears, an activity judgment about the NOx sensor cell is formed.

Abstract: An abnormality diagnostic apparatus for a gas sensor includes a NOx sensor includes a main pump cell, an auxiliary pump cell, and a detection cell. The apparatus diagnoses at least one of the detection cell, the main pump cell, and the auxiliary pump cell for an abnormality, based on at least one of a rising characteristic of a NOx output of the detection cell immediately after a start of detection of the NOx output, its peak value, and its subsequent falling characteristic. An abnormality of the detection cell is determined if a speed with which the NOx output rises is small; an abnormality of at least one of the main pump cell and the auxiliary pump cell is determined if a speed with which the NOx output falls is small; and an abnormality of the detection cell is determined if the peak value of the NOx output is small.

Abstract: An object of the present invention is to accurately diagnose an abnormality of a fuel property detection apparatus that detects a fuel property based on a capacitance between electrodes. The abnormality detection apparatus for a fuel property detection apparatus of the present invention detects an abnormality of a fuel property detection apparatus that detects a fuel property based on a measurement value of a capacitance between a pair of electrodes installed on a fuel supply channel of an internal combustion engine that can use a fuel that includes a predetermined fuel component that has a characteristic such that a permittivity thereof changes according to a frequency of an electric field.

Abstract: A heating apparatus of the present invention includes a press member that undergoes driven rotation by contacting a heating member that rotates, the press member conveying a recording medium while nipping the recording medium between the press member and the heating member; a contact and separation mechanism that contacts the press member against the heating member and separates the press member away from the heating member; and a drive mechanism that rotationally drives the press member when the press member is separated from the heating member by the contact and separation mechanism.

Abstract: A control apparatus controls an automatic stop of an engine mounted on a vehicle so as to automatically stop the engine if a predetermined stop condition is satisfied, the stop condition including a condition that a running speed of the vehicle is a prescribed speed or less. The control apparatus includes a prediction unit and a prohibition unit. The prediction unit predicts whether or not the next automatic stop time of the engine is less than a prescribed time capable of obtaining a fuel saving benefit based on a history of a vehicle stop time or an automatic stop time of the engine. The prohibition unit prohibits the next automatic stop of the engine if the prediction unit predicts that the next automatic stop time of the engine is less than the prescribed time.

Abstract: A cylinder head of an internal combustion engine is fitted with rocker arms. Camshafts are disposed so that the rocker arms and cams will be brought into contact with each other. The camshafts are rotatably supported by lower bearings, which supports the camshafts from below, and by upper bearings integrated with a head cover. The head cover is provided with visual observation windows that make it possible to see valve system parts through the head cover. A visual observation window covers for covering the visual observation windows are fixed to the head cover.