Patents by Inventor Takashi Shimada

Takashi Shimada has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9481770
    Abstract: A carbon fiber composite material which includes a carbon fiber sheet as a reinforcing material and a thermoplastic resin as a matrix resin, the carbon fiber sheet exhibiting a work per areal weight of 1×10?3 to 30×10?3 [(N·mm)/(g/m2)] in a tensile test using a specimen having a width of 25 mm. The carbon fiber composite material exhibits excellent flowability in molding and ensures excellent moldability even when molded into a complicated shape. Further, the composite material can yield a molded product which has high mechanical properties with minimized dispersion, thus being suitable for press molding.
    Type: Grant
    Filed: May 15, 2013
    Date of Patent: November 1, 2016
    Assignee: Toray Industries, Inc.
    Inventors: Yoshihiro Naruse, Katsuhiro Miyoshi, Takashi Shimada, Takafumi Hashimoto, Tetsuya Ohara
  • Patent number: 9469740
    Abstract: A carbon-fiber-reinforced plastic prepared by impregnating a matrix resin into a sheet-like base material includes discontinuous carbon fibers, wherein a content ratio of carbon fibers having lengths of 10 mm or longer in the base material is 60 wt % or more relative to a total amount of the carbon fibers, and an average value of orientation degrees of carbon fibers contained in the base material is 2-10.
    Type: Grant
    Filed: April 18, 2012
    Date of Patent: October 18, 2016
    Assignee: Toray Industries, Inc.
    Inventors: Takafumi Hashimoto, Hirohito Minowa, Takashi Shimada, Masahiro Hashimoto, Katsuhiro Miyoshi, Yoshihiro Naruse
  • Patent number: 9452741
    Abstract: A vehicle brake system includes a slave cylinder configured to drive an electric motor and generate a brake fluid pressure by moving pistons with a ball screw shaft; normally open type master cut valves that communicate/shut off between the slave cylinder and a master cylinder; and a control unit that controls the electric motor to close the master cut valves and limit a displacement of the ball screw shaft on the basis of a reference position during operation of a VSA device.
    Type: Grant
    Filed: July 3, 2014
    Date of Patent: September 27, 2016
    Assignee: HONDA MOTOR CO., LTD.
    Inventors: Kazuharu Kidera, Takashi Shimada, Soichiro Ueura
  • Patent number: 9448240
    Abstract: A thiol probe for a protein, which promotes ionization in proteomic analysis using mass spectrometry and can be used even for a protein that has a high degree of hydrophobicity and quickly turns over, and is represented by the following formula (I): In formula (I), R1 represents a linker group, and R2 represents a substituted ammonium group or a substituted amino group. A mass spectrometry method for a protein, includes the steps of obtaining a modified protein by reacting the thiol probe with a protein to be subjected to mass spectrometry and subjecting the modified protein to mass spectrometry.
    Type: Grant
    Filed: August 17, 2012
    Date of Patent: September 20, 2016
    Assignee: SHIMADZU CORPORATION
    Inventors: Takashi Shimada, Taka-Aki Sato, Koichi Tanaka
  • Patent number: 9446750
    Abstract: A valve system of a braking device provided with a stroke simulator that is connected via a connection passage with a pipe for making a master cylinder communicate with a wheel cylinder; and a third shut-off valve that is a solenoid valve and performs opening and closing of a communication between the master cylinder and the stroke simulator, wherein the third shut-off valve is a normally closed valve; and the valve system opens the third shut-off valve by applying a start-up voltage, thereafter keeps the open state of the third shut-off valve by alternately applying a holding voltage that is lower than the start-up voltage and the start-up voltage, in order to prevent heat generated in the valve from becoming excessively high even while keeping the open state of the valve.
    Type: Grant
    Filed: September 23, 2014
    Date of Patent: September 20, 2016
    Assignees: Honda Motor Co., Ltd., Nissin Kogyo Co., Ltd.
    Inventors: Takashi Shimada, Hiroaki Tokoi, Takaaki Komaba
  • Publication number: 20160252522
    Abstract: A method of proteolyzing a protein, including immobilizing a protein in at least one pore of a porous body, and contacting the protein immobilized in the pore and a protease immobilized on a solid surface such that the protease selectively accesses a site of the protein and proteolyzes the protein at the site.
    Type: Application
    Filed: March 8, 2016
    Publication date: September 1, 2016
    Applicant: SHIMADZU CORPORATION
    Inventors: Takashi SHIMADA, Noriko FUKAO, Chikage AOKI, Taka-Aki SATO
  • Patent number: 9420769
    Abstract: A chimeric non-human animal having an in vivo human hepatocyte population, wherein the effects of non-human animal cells on drug metabolism are suppressed or deleted is provided. A method for producing a chimeric non-human animal that lacks a drug-metabolizing system or has a suppressed drug-metabolizing system and is provided with a drug-metabolizing system driven by human hepatocytes, is provided. The method comprises transplanting human hepatocytes into a non-human animal characterized by (i) being immunodeficient, (ii) having liver damage, and (iii) lacking the functions of an endogenous Cyp3a gene.
    Type: Grant
    Filed: October 12, 2012
    Date of Patent: August 23, 2016
    Assignees: PHOENIXBIO CO., LTD., NATIONAL UNIVERSITY CORPORATION TOTTORI UNIVERSITY
    Inventors: Mitsuo Oshimura, Yasuhiro Kazuki, Chise Mukaidani, Takashi Shimada, Masakazu Kakuni, Satoko Hamamura, Hidetaka Kamimura, Akio Kawamura, Naoyuki Nakada, Masato Ohbuchi, Kota Kato
  • Patent number: 9403519
    Abstract: The object of the present invention is to provide a vehicle brake system capable of appropriately setting an upper limit value of hydraulic pressure of a by-wire brake during stopping of a vehicle in accordance with conditions. When the vehicle is stopped, a maximum allowable drive voltage calculation unit sets a maximum allowable drive voltage to V2, and sets a brake pressure generated by a motor to P2. When the vehicle is stopped, if a duration time of stopping of the vehicle or a duration time of generation of the brake pressure exceeds a reference value, the maximum allowable drive voltage calculation unit sets the maximum allowable drive voltage to V3, and sets the brake pressure generated by the motor to P3 which is lower than P2.
    Type: Grant
    Filed: October 1, 2014
    Date of Patent: August 2, 2016
    Assignee: Honda Motor Co., Ltd.
    Inventors: Takashi Shimada, Soichiro Ueura, Kazuharu Kidera
  • Publication number: 20160159895
    Abstract: To provide an antibody against FGF23 and a pharmaceutical composition such as a preventive or therapeutic agent which can prevent or treat by suppressing an action of FGF23 by using the antibody. An antibody or its functional fragment against human FGF23 produced by hybridoma C10 (Accession No. FERM BP-10772).
    Type: Application
    Filed: February 10, 2016
    Publication date: June 9, 2016
    Applicant: KYOWA HAKKO KIRIN CO., LTD.
    Inventors: Yuji Yamazaki, ltaru Urakawa, Hitoshi Yoshida, Yukiko Aono, Takeyoshi Yamashita, Takashi Shimada, Hisashi Hasegawa
  • Patent number: 9333952
    Abstract: In a brake-by-wire brake system which includes a motor actuated cylinder configured to produce a brake fluid pressure according to an operating stroke thereof and an electric motor for actuating the motor actuated cylinder, the control mode is normally based on a fluid pressure control, but is switched to a stroke control when the brake pedal is released for the purpose of quickly reducing the operating stroke of the motor actuated cylinder to an initial value. To avoid a sudden increase in the noises of the electric motor at the time of switching from the fluid pressure control to the stroke control, a limit circuit limits electric current supplied to the electric motor when the control mode is switched from the fluid pressure control to the stroke control.
    Type: Grant
    Filed: October 2, 2014
    Date of Patent: May 10, 2016
    Assignee: Honda Motor Co., Ltd.
    Inventors: Soichiro Ueura, Kazuharu Kidera, Takashi Shimada
  • Patent number: 9290569
    Abstract: To provide an antibody against FGF23 and a pharmaceutical composition such as a preventive or therapeutic agent which can prevent or treat by suppressing an action of FGF23 by using the antibody. An antibody or its functional fragment against human FGF23 produced by hybridoma C10 (Accession No. FERM BP-10772).
    Type: Grant
    Filed: February 2, 2011
    Date of Patent: March 22, 2016
    Assignee: Kyowa Hakko Kirin Co., Ltd.
    Inventors: Yuji Yamazaki, Itaru Urakawa, Hitoshi Yoshida, Yukiko Aono, Takeyoshi Yamashita, Takashi Shimada, Hisashi Hasegawa
  • Publication number: 20160048810
    Abstract: A method for extracting a road construction method executed by a computer as a process includes acquiring measured data of a volume of traffic on a specific road surface when extracting a candidate of a road construction method to be applied to the specific road surface out of a plurality of road construction methods including at least repair work from a foundation of a road and repair work of a surface layer of a road, and extracting the candidate of a road construction method to be applied to the specific road surface based on the acquired measured data.
    Type: Application
    Filed: April 13, 2015
    Publication date: February 18, 2016
    Applicant: FUJITSU LIMITED
    Inventors: Takashi SHIMADA, Hiroyuki TANI, Kosei TAKANO, Hiroshi SASAKI, Fumiaki SUZUKI
  • Publication number: 20160039401
    Abstract: Provided is a brake system for a vehicle including an input side hydraulic system, an output side hydraulic system, a first and a second shutoff valves to shut off flowing of the brake fluid between the input side hydraulic system and the output side hydraulic system when closed, a first and a second out-valves through which the brake fluid flows into a reservoir unit when opened, and a control unit to control a motor cylinder device of the output side hydraulic system to generate the brake fluid pressure according to the operational amount of a brake pedal. The control unit opens one or both of the first and the second shutoff valves and the first and the second out-valves when output characteristic of the brake fluid pressure generated by the motor cylinder device shifts from basic characteristic.
    Type: Application
    Filed: August 10, 2015
    Publication date: February 11, 2016
    Inventors: Takashi SHIMADA, Soichiro UEURA
  • Publication number: 20160011168
    Abstract: A method for detecting epithelial-mesenchymal transition of a cell includes measuring a level of serine in a metabolic substance mixture prepared from culture of the cell, and comparing the level of serine with a reference for serine such that epithelial-mesenchymal transition of the cell is detected based on at least the level of serine compared with the reference.
    Type: Application
    Filed: July 8, 2015
    Publication date: January 14, 2016
    Applicant: SHIMADZU CORPORATION
    Inventors: Noriko IWAMOTO, Takashi SHIMADA
  • Patent number: 9213273
    Abstract: An image forming apparatus includes: an image bearing member for bearing a toner image; a belt for conveying the toner image; and a transfer device for rubbing the belt, and a surface of the transfer device, which is brought into contact with the belt includes linear concave portions or linear convex portions. The image forming apparatus of the present invention prevents a friction force between the belt and the transfer device rubbing the belt from increasing and brings a transfer member into a stable contact with the belt for conveying the toner image, thereby suppressing increase in drive torque of the belt which rubs the transfer device and suppressing occurrence of image failure.
    Type: Grant
    Filed: April 18, 2014
    Date of Patent: December 15, 2015
    Assignee: CANON KABUSHIKI KAISHA
    Inventors: Kazuhiro Doda, Masaru Shimura, Shigeru Hoashi, Kenji Kanari, Seiji Saito, Takashi Shimada, Takaaki Akamatsu, Michio Uchida, Ken Nakagawa, Takamitsu Soda, Shuichi Tetsuno
  • Publication number: 20150353713
    Abstract: A stampable sheet includes a resin and carbon fiber sheet including fiber bundles of discontinuous carbon fibers, wherein the carbon fiber sheet includes fiber bundles having a bundle width of 50 ?m or greater and opened fibers ranging from fiber bundles having a bundle width less than 50 ?m to fibers obtained by opening to the single-fiber level. When the direction along which the opened fibers have been oriented most is a 0° direction and the range of from the 0° to 90° direction is divided into angular zones, the distribution curve showing the proportion of the number of fiber bundles in each angular zone to that in all angular zones and the distribution curve showing the proportion of the number of opened fibers in each angular zone to that in all angular zones are reverse to each other in terms of gradient of the 0° to 90° direction.
    Type: Application
    Filed: February 19, 2014
    Publication date: December 10, 2015
    Applicant: TORAY INDUSTRIES, INC.,
    Inventors: Katsuhiro Miyoshi, Takashi Shimada, Takafumi Hashimoto, Tetsuya Ohara, Yoshihiro Naruse
  • Patent number: 9171363
    Abstract: A road surface survey device specifies a position at which abnormality is detected at one of a position at which abnormality on pavement of a road surface is detected from an image of a road captured by a camera and a position at which abnormality on pavement of a road surface is detected from a change in an acceleration measured when a car runs on the road surface by a G sensor. Further, the road surface survey device derives conditions that abnormality which is not detected at the specified position can be detected, and outputs an instruction of a resurvey for the specified position under the derived conditions.
    Type: Grant
    Filed: November 6, 2012
    Date of Patent: October 27, 2015
    Assignee: FUJITSU LIMITED
    Inventors: Fumiaki Suzuki, Takashi Shimada, Kazuyoshi Kuzunishi, Hiroyuki Tani, Kosei Takano, Takuji Numata
  • Publication number: 20150299090
    Abstract: The Spiro compound represented by the following general formula [Ia], its pharmaceutically acceptable salt or a solvate thereof
    Type: Application
    Filed: November 17, 2014
    Publication date: October 22, 2015
    Inventors: Takashi Shimada, Hiroshi Ueno, Kazuhiro Tsutsumi, Kouichi Aoyagi, Tomoyuki Manabe, Shin-ya Sasaki, Susumu Katoh
  • Publication number: 20150292146
    Abstract: A stampable sheet includes discontinuous carbon fibers and a thermoplastic resin as a matrix resin, wherein viscosity ? of the stampable sheet in a state where the matrix resin in the stampable sheet is molten is ?0??<?0 exp(0.20Vf)(Pa·s), and ratio Z of refined carbon fiber bundles (A) in which Mn/(Ln×D) is less than 8.5×10?1 (mg/mm2) to the total weight of carbon fibers in the stampable sheet is 10?Z<70 (wt %). The configuration makes it possible to provide a stampable sheet provided with a controlled range of conditions, and to achieve both high flowability during molding and high mechanical properties after molding.
    Type: Application
    Filed: October 15, 2013
    Publication date: October 15, 2015
    Inventors: Katsuhiro Miyoshi, Takashi Shimada, Takafumi Hashimoto, Tetsuya Ohara, Yoshihiro Naruse
  • Publication number: 20150183941
    Abstract: A carbon fiber composite material which includes a carbon fiber sheet as a reinforcing material and a thermoplastic resin as a matrix resin, the carbon fiber sheet exhibiting a work per areal weight of 1×10?3 to 30×10?3 [(N·mm)/(g/m2)] in a tensile test using a specimen having a width of 25 mm. The carbon fiber composite material exhibits excellent flowability in molding and ensures excellent moldability even when molded into a complicated shape. Further, the composite material can yield a molded product which has high mechanical properties with minimized dispersion, thus being suitable for press molding.
    Type: Application
    Filed: May 15, 2013
    Publication date: July 2, 2015
    Applicant: Toray Industries, Inc.
    Inventors: Yoshihiro Naruse, Katsuhiro Miyoshi, Takashi Shimada, Takafumi Hashimoto, Tetsuya Ohara