Patents by Inventor Takeshi Wada
Takeshi Wada has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11932666Abstract: Provided is a polymerizable compound represented by a Formula E-1 or Formula E-2 shown in the description. In Formula E-1 or Formula E-2, R1 represents an alkoxy group, —NRN2, a hydroxy group, an aryl group, or an alkyl group, wherein RN each independently represents a hydrogen atom or an alkyl group having 1 to 10 carbon atoms; n represents an integer from 1 to 5; R3 represents a hydrogen atom, an acetyl group, a phenoxyacetyl group, a pivaloyl group, a benzyl group, a 4-methoxybenzyl group, a benzoyl group, a triphenylmethyl group, a 4,4?-dimethoxytrityl (DMTr) group, a 4-methoxytrityl (MMTr) group, a 9-phenylxanthenyl group, a trimethylsilyl group, a cyanomethoxymethyl group, a 2-(cyanoethoxy)ethyl group, or a cyanoethoxymethyl group; and X represents a structure represented by any one of Formula B-1 to Formula B-5 shown in the description.Type: GrantFiled: October 13, 2022Date of Patent: March 19, 2024Assignee: TOKYO UNIVERSITY OF SCIENCE FOUNDATIONInventors: Takeshi Wada, Tatsuya Saito, Yuka Ishii, Yohei Nukaga
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Patent number: 11819600Abstract: A waste liquid receptacle includes first and second cover members for covering first and second openings, respectively. The first cover member is made of a material that is configured to: (i) be plastically deformed upward by a first suction force in a state where a second negative pressure is generated in an upper space; and (ii) plastically deform downward by a depressing force against the first cover member downward in a state where an openable and closable lid is open and the second negative pressure is released. The second cover member is made of a material that is configured: (i) not to be plastically deformed by a second suction force in a state where a first negative pressure is generated in a waste liquid receipt space; and (ii) to be broken without being plastically deformed when a depressing force is applied to the first cover member.Type: GrantFiled: September 15, 2020Date of Patent: November 21, 2023Assignee: DAIKEN MEDICAL CO., LTD.Inventors: Masayuki Uruma, Takeshi Wada, Kouhei Kazuhara, Yoshiro Ohashi
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Publication number: 20230108357Abstract: Provided is a polymerizable compound represented by a Formula E-1 or Formula E-2 shown in the description. In Formula E-1 or Formula E-2, R1 represents an alkoxy group, —NRN2, a hydroxy group, an aryl group, or an alkyl group, wherein RN each independently represents a hydrogen atom or an alkyl group having 1 to 10 carbon atoms; n represents an integer from 1 to 5; R3 represents a hydrogen atom, an acetyl group, a phenoxyacetyl group, a pivaloyl group, a benzyl group, a 4-methoxybenzyl group, a benzoyl group, a triphenylmethyl group, a 4,4?-dimethoxytrityl (DMTr) group, a 4-methoxytrityl (MMTr) group, a 9-phenylxanthenyl group, a trimethylsilyl group, a cyanomethoxymethyl group, a 2-(cyanoethoxy)ethyl group, or a cyanoethoxymethyl group; and X represents a structure represented by any one of Formula B-1 to Formula B-5 shown in the description.Type: ApplicationFiled: October 13, 2022Publication date: April 6, 2023Inventors: Takeshi Wada, Tatsuya Saito, Yuka Ishii, Yohei Nukaga
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Patent number: 11542292Abstract: Provided a polymerizable compound represented by the following Formula A-1 or Formula A-2: In Formula A-1 or Formula A-2, R1 represents an electron-donating group; n represents an integer from 1 to 5; R2 represents a hydrogen atom, a halogen atom, or —ORO, wherein RO represents a hydrogen atom, an alkyl group, or a protecting group of a hydroxy group; R3 represents a hydrogen atom or a protecting group of a hydroxy group; and X represents a structure represented by any one of Formula B-1 to Formula B-5.Type: GrantFiled: November 9, 2017Date of Patent: January 3, 2023Assignee: TOKYO UNIVERSITY OF SCIENCE FOUNDATIONInventors: Takeshi Wada, Tatsuya Saito, Yuka Ishii, Yohei Nukaga
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Publication number: 20220380763Abstract: A novel anti-tumor agent capable of delivering siRNA or shRNA specifically to pancreatic cancer cells and suppressing tumor growth, invasion, and metastasis of pancreatic cancer is provided. The present invention provides a nucleic acid delivery enhancer for delivering siRNA or shRNA into cells, which consists of a folic acid-cationic oligopeptide complex. The present invention also provides an anti-tumor agent having siRNA or shRNA capable of binding to mRNA or snoRNA expressed in pancreatic cancer cells to inhibit its expression and a folic acid-cationic oligopeptide complex. The siRNA is capable of binding to RNA selected from the group consisting of, for example, SNORA18 snoRNA, NUP85 mRNA, WASF2 mRNA, and SNORA22 snoRNA.Type: ApplicationFiled: October 26, 2020Publication date: December 1, 2022Applicants: NATIONAL UNIVERSITY CORPORATION KOCHI UNIVERSITY, TOKYO UNIVERSITY OF SCIENCE FOUNDATIONInventors: Keisuke TANIUCHI, Takeshi WADA, Rintaro HARA, Kazuki SATO, Kazunori TAKAGI
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Publication number: 20220331505Abstract: A negative pressure is generated in an upper space of a canister due to a suction force of a suction source and, then, a negative pressure is generated in a waste liquid receiving space of a cylindrical body in response to the generation of the negative pressure in the upper space . At this stage of the operation, a first covering member that covers a first opening that opens facing the upper space in a waste liquid treating agent storing portion plastically deforms upward by a suction force caused by a negative pressure in the upper space. On the other hand, when a depressing force that pushes the first covering member downward is applied to the first covering member in a state where an opening and closing lid of the canister is opened so that a negative pressure in the upper space is released, the depressing force is transmitted to a second covering member so that the second covering member is broken.Type: ApplicationFiled: September 15, 2020Publication date: October 20, 2022Applicant: DAIKEN MEDICAL CO., LTD.Inventors: Masayuki URUMA, Takeshi WADA, Kouhei KAZUHARA, Yoshiro OHASHI
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Publication number: 20220307019Abstract: A double-stranded nucleic acid complex is a double-stranded nucleic acid complex including a first nucleic acid strand and a second nucleic acid strand bonded to each other, the second nucleic acid strand including a complementary region having a base sequence complementary to the first nucleic acid strand; the first nucleic acid strand including natural nucleosides and non-natural nucleosides; some of the nucleosides in at least one nucleic acid strand selected from the group consisting of the first nucleic acid strand and the second nucleic acid strand being bonded together by bonds including asymmetric phosphorus atoms; and absolute configurations of the asymmetric phosphorus atoms being regulated.Type: ApplicationFiled: March 25, 2020Publication date: September 29, 2022Applicants: National University Corporation Tokyo Medical and Dental University, Wave Life Sciences LtdInventors: Takanori YOKOTA, Takeshi WADA, Mamoru SHIMIZU
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Publication number: 20220127301Abstract: To provide a chiral reagent or a salt thereof. The chiral reagent has following chemical formula (I). In the formula (I), G1 and G2 are independently a hydrogen atom, a nitro group (—NO2), a halogen atom, a cyano group (—CN), a group of formula (II) or (III), or both G1 and G2 taken together to form a group of formula (IV).Type: ApplicationFiled: September 2, 2021Publication date: April 28, 2022Inventors: Mamoru Shimizu, Takeshi Wada
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Publication number: 20210371288Abstract: A porous amorphous silicon which enables improvement in battery performances such as charge/discharge efficiency and battery capacity when used as the anode material; a method for producing a porous amorphous silicon, capable of producing a porous amorphous silicon composed entirely of amorphous silicon at relatively low cost in a short time; and a secondary battery using the porous amorphous silicon as the anode material. A molten metal containing metal and silicon is cooled at a cooling rate of 106 K/sec or more to form an eutectic alloy including the metal and the silicon, and then the metal is selectively eluted from the eutectic alloy with an acid or an alkali to obtain a porous amorphous silicon. The porous amorphous silicon has a lamellar or columnar structure having a mean lamellar diameter or a mean column diameter of 1 nm to 100 nm.Type: ApplicationFiled: September 13, 2019Publication date: December 2, 2021Applicant: TOHOKU UNIVERSITYInventors: Junpei OKADA, Koji NAKAYAMA, Takeshi WADA
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Patent number: 11180857Abstract: A method for producing a porous member, whereby a member having smaller microgaps can be produced, and additionally, the outermost surface alone can be made porous and a porous layer can be formed on the surface while maintaining the characteristics of portions in which no porous layer is formed, is provided.Type: GrantFiled: January 16, 2017Date of Patent: November 23, 2021Assignees: TOHOKU TECHNO ARCH CO., LTD., TPR CO., LTD.Inventors: Takeshi Wada, Hidemi Kato
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Patent number: 11136346Abstract: To provide a chiral reagent or a salt thereof. The chiral reagent has following chemical formula (I). In the formula (I), G1 and G2 are independently a hydrogen atom, a nitro group (—NO2), a halogen atom, a cyano group (—CN), a group of formula (II) or (III), or both G1 and G2 taken together to form a group of formula (IV).Type: GrantFiled: May 19, 2020Date of Patent: October 5, 2021Assignee: WAVE LIFE SCIENCES LTD.Inventors: Mamoru Shimizu, Takeshi Wada
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Patent number: 10935226Abstract: A lighting device includes a first light source unit having a first light source row made up of a plurality of light sources, and a first light source board, onto which the light sources making up the first light source row are mounted, a second light source unit having a second light source row made up of a plurality of light sources, and a second light source board, onto which the light sources making up the second light source row are mounted, and a light guide plate having a plate-like shape and having a first light-incident face where light emitted from the light sources is incident, and a second light-incident face disposed on an opposite side from the first light-incident face where light emitted from the light sources is incident.Type: GrantFiled: June 6, 2018Date of Patent: March 2, 2021Assignee: SHARP KABUSHIKI KAISHAInventors: Takeshi Wada, Takuya Ohnishi
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Publication number: 20200385420Abstract: To provide a chiral reagent or a salt thereof. The chiral reagent has following chemical formula (I). In the formula (I), G1 and G2 are independently a hydrogen atom, a nitro group (—NO2), a halogen atom, a cyano group (—CN), a group of formula (II) or (III), or both G1 and G2 taken together to form a group of formula (IV).Type: ApplicationFiled: May 19, 2020Publication date: December 10, 2020Inventors: Mamoru Shimizu, Takeshi Wada
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Patent number: 10844374Abstract: Chimeric single-stranded polynucleotides and double-stranded antisense agents useful for modifying the expression of a target gene by means of an antisense effect are disclosed. The chimeric single-stranded antisense polynucleotide and double-stranded antisense agents comprise a central nucleotide region flanked by a first 5?-wing region and a first 3?-wing region of modified nucleotides, which are themselves flanked by a second 5?-wing region and/or a second 3?-wing region of nucleotides that have a low affinity for proteins and/or that have higher resistance to DNase or RNase than a natural DNA or RNA and are missing in a cell when the chimeric polynucleotide delivered. The double-stranded antisense agent further comprises a complementary strand annealed to the antisense strand. The polynucleotide can be used to modify RNA transcription levels, miRNA activity, or protein levels in cells.Type: GrantFiled: June 7, 2017Date of Patent: November 24, 2020Assignee: National University Corporation Tokyo Medical and Dental UniversityInventors: Takanori Yokota, Kazutaka Nishina, Hidehiro Mizusawa, Takeshi Wada
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Patent number: 10763511Abstract: A method for producing porous graphite capable of realizing higher durability, output and capacity, and porous graphite. A carbon member having microvoids is obtained by a dealloying step for selectively eluting other non-carbon main components into a metal bath by immersing a carbon-containing material, composed of a compound including carbon or an alloy or non-equilibrium alloy, in the metal bath, wherein the metal bath has a solidifying point lower than the melting point of the carbon-containing material, and is controlled to a temperature lower than the minimum value of a liquidus temperature within a composition fluctuation range extending from the carbon-containing material to carbon by reducing the other non-carbon main components. The carbon member obtained in the dealloying step is graphitized by heating in a graphitization step. The carbon member graphitized in the graphitization step is subjected to activation treatment by an activation step.Type: GrantFiled: October 23, 2018Date of Patent: September 1, 2020Assignees: TOHOKU TECHNO ARCH CO., LTD., TPR CO., LTD.Inventors: Hidemi Kato, Seung-Geun Yu, Takeshi Wada
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Publication number: 20200208824Abstract: A lighting device includes a first light source unit having a first light source row made up of a plurality of light sources, and a first light source board, onto which the light sources making up the first light source row are mounted, a second light source unit having a second light source row made up of a plurality of light sources, and a second light source board, onto which the light sources making up the second light source row are mounted, and a light guide plate having a plate-like shape and having a first light-incident face where light emitted from the light sources is incident, and a second light-incident face disposed on an opposite side from the first light-incident face where light emitted from the light sources is incident.Type: ApplicationFiled: June 6, 2018Publication date: July 2, 2020Inventors: TAKESHI WADA, TAKUYA OHNISHI
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Patent number: 10696711Abstract: To provide a chiral reagent or a salt thereof. The chiral reagent has following chemical formula (I). In the formula (I), G1 and G2 are independently a hydrogen atom, a nitro group (—NO2), a halogen atom, a cyano group (—CN), a group of formula (II) or (III), or both G1 and G2 taken together to form a group of formula (IV).Type: GrantFiled: November 6, 2018Date of Patent: June 30, 2020Assignee: WAVE LIFE SCIENCES LTD.Inventors: Mamoru Shimizu, Takeshi Wada
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Publication number: 20190364127Abstract: A server device includes: a storage for storing a plurality of web page files each corresponding to a plurality of matters to be reported, the plurality of web page files being associated with matter IDs and URL information; a receiver for receiving, from a report originator terminal, web page file update information along with a matter ID for a particular matter to be reported; a web page file updating unit for reading out a web page file for the particular matter to be reported from the storing means according to URL information associated with the received matter ID and updating the web page file according to the web page file update information; a URL updating unit for issuing a new file name for the updated web page file and updating a URL for the web page file with the issuance of the new file name.Type: ApplicationFiled: August 12, 2019Publication date: November 28, 2019Inventor: Takeshi WADA
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Patent number: 10428019Abstract: The disclosed and claimed compounds are chiral auxiliaries useful for efficiently producing a phosphorus atom-modified nucleic acid derivative with high stereoregularity. The disclosed and claimed compounds include those represented by the following formula (I) or formula (XI) for introducing the chiral auxiliaries.Type: GrantFiled: September 22, 2011Date of Patent: October 1, 2019Assignee: WAVE LIFE SCIENCES LTD.Inventors: Takeshi Wada, Mamoru Shimizu
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Publication number: 20190270765Abstract: Provided a polymerizable compound represented by the following Formula A-1 or Formula A-2: In Formula A-1 or Formula A-2, R1 represents an electron-donating group; n represents an integer from 1 to 5; R2 represents a hydrogen atom, a halogen atom, or —ORO, wherein RO represents a hydrogen atom, an alkyl group, or a protecting group of a hydroxy group; R3 represents a hydrogen atom or a protecting group of a hydroxy group; and X represents a structure represented by any one of Formula B-1 to Formula B-5.Type: ApplicationFiled: November 9, 2017Publication date: September 5, 2019Inventors: Takeshi Wada, Tatsuya Saito, Yuka Ishii, Yohei Nukaga