Abstract: The present invention provides a magnetic bead purification system, including: a housing; a liquid path treatment system provided inside the housing, the liquid path treatment system being connectable to a reagent barrel and a waste liquid barrel; a sample addition needle group connected to the liquid path treatment system, the sample addition needle group being movable within the housing and connected to the liquid path treatment system, so as to receive a reagent from the liquid path treatment system or to discharge a waste liquid to the liquid path treatment system; a purification magnetic separation system, including a magnetic element, the purification magnetic separation system being controllable to apply a lateral magnetic force to a purification treatment position inside the housing or stop the application of the magnetic force by the magnetic element; and a purification station system movable between a purification treatment position inside the housing and a loading position outside the housing, the

Abstract: This application discloses a service packet forwarding method and related apparatus. In the service packet forwarding method, when receiving a packet sent by any second virtual resource module connected to a first service function forwarder (SFF), the first SFF dynamically determines a forwarding path of the packet based on configuration information of a second virtual resource module for implementing a second service function, to achieve dynamic load balancing on the packet instead of relying on a service function chain ingress node to perform load balancing, so as to reduce pressure on the service function chain ingress node.

Abstract: The present invention relates to a large-scale magnetic purification system, including: a liquid storage apparatus, capable of being connected to a liquid source and a waste liquid barrel through a liquid path system; a stirring system mounted above the liquid storage apparatus, where a stirring paddle of the stirring system is inserted into the liquid storage apparatus for stirring; magnets mounted around the liquid storage apparatus; a magnet actuating mechanism for manipulating the magnets to move away from or close to the liquid storage apparatus; and a control system, connected to the liquid path system, the magnet actuating mechanism, and the stirring system and controlling the liquid path system, the magnet actuating mechanism, and the stirring system.

Abstract: A positioning and information transmission method of a hydrological monitoring device in a single-free area combines a wireless communication technology with a hydrodynamics-based hydrological monitoring device, which can solve the problem of hydrological monitoring information transmission in a signal-free area such as a hydraulic tunnel. First, magnetic beacons each composed of an LoRa (long distance radio) terminal device and an ultra-wideband technology are arranged at the top of the interior of a signal-free tunnel at an interval of 500 m. When a hydrological monitoring device in use enters a coverage area of the magnetic beacon, the LoRa terminal device in the magnetic beacon will automatically start an internal communication protocol and receive data acquired by the device by monitoring, the data is transmitted based on a mutual LoRa communication protocol between the magnetic beacons, and finally, the data is transmitted to a ground central control system for storage.

Abstract: A sample processing apparatus (100) and a use method therefor. The sample processing apparatus (100) comprises a uniform mixing mechanism (130) and a magnetic attraction mechanism (140). The sample processing apparatus (100) further comprises at least one of a sample tube (110) and a reaction tube (120). The uniform mixing mechanism (130) is configured to perform uniform mixing processing on a biological sample in the sample tube (110) and/or a biological sample in the reaction tube (120). The magnetic attraction mechanism (140) comprises a magnet (141). The magnet (141) can move relative to the sample tube (110) and/or the reaction tube (120), so as to perform magnetic attraction processing on the biological sample in the sample tube (110) and/or the biological sample in the reaction tube (120).

Abstract: In a method for enabling a message receive end to quickly confirm a certificate status, a defined field of a certificate includes classification information of the certificate, and a defined field of a certificate revocation list includes classification information of a revoked certificate, so that the receive end can quickly narrow a searching or matching range in massive records of the certificate revocation list based on the classification information carried in the certificate of a transmit end.

Abstract: A sample processing apparatus (100) and a use method therefor. The sample processing apparatus (100) comprises a uniform mixing mechanism (130) and a magnetic attraction mechanism (140). The sample processing apparatus (100) further comprises at least one of a sample tube (110) and a reaction tube (120). The uniform mixing mechanism (130) is configured to perform uniform mixing processing on a biological sample in the sample tube (110) and/or a biological sample in the reaction tube (120). The magnetic attraction mechanism (140) comprises a magnet (141). The magnet (141) can move relative to the sample tube (110) and/or the reaction tube (120), so as to perform magnetic attraction processing on the biological sample in the sample tube (110) and/or the biological sample in the reaction tube (120).

Abstract: An automatic extraction device and a use method therefor. The automatic extraction device comprises a sample processing apparatus (100), a portal frame (200), a consumable assembly (300), and a pipetting apparatus (400). The sample processing apparatus (100) comprises a uniform mixing mechanism (130) and a magnetic attraction mechanism (140), which are respectively used for performing uniform mixing processing and magnetic attraction processing on a biological sample. The portal frame (200) comprises a base (201) and a moving beam (202) capable of moving relative to the base (201). The sample processing apparatus (100) and the consumable assembly (300) are provided on the base (201). The pipetting apparatus (400) is provided on the moving beam (202) for implementing a pipetting operation between the consumable assembly (300) and the sample processing apparatus (100).

Abstract: The present invention relates to an anisomycin derivative represented by general formula (I) or pharmaceutically acceptable salts, solvates and stereoisomers thereof. According to the present invention, it is found that anisomycin and derivatives thereof have the effect of promoting insulin secretion under high blood sugar concentrations, and can treat diabetes and prevent the occurrence of hypoglycemia. It is found, by studying its mechanism of action, that the anisomycin derivative is highly related to GLP-1R, indicating that the anisomycin derivative is a small molecule GLP-1R agonist, which can effectively treat a variety of GLP-1R-mediated diseases including obesity and diabetes, and has good commercial application prospects and scientific research value.

Abstract: Free-standing non-fouling polymers and polymeric compositions, monomers and macromonomers for making the polymers and polymeric compositions, objects made from the polymers and polymeric compositions, and methods for making and using the polymers and polymeric compositions

Abstract: Embodiments of this application provide a packet forwarding method, a route sending and receiving method, and related apparatus. The method is applied to a data center in a non-uniform memory access (NUMA) architecture. The data center includes a server and a network device, and the server includes a first NUMA node and a second NUMA node. The method includes: The first interface processing unit (IPU) receives a first packet from the network device, where the first packet is a packet to be sent to the first virtual machine in the first NUMA node. The first IPU sends the first packet to the first virtual machine. The second IPU receives a second packet from the network device, where the second packet is a packet to be sent to the second virtual machine in the second NUMA node. The second IPU sends the second packet to the second virtual machine.

Abstract: Provided is a high-loading and alkali-resistant protein A magnetic bead. The magnetic bead can maintain chemical stability under pH 2-14 and has an immunoglobulin G (IgG) binding capacity greater than 50 mg/mL. Further provided is a method for purifying and/or detecting an immunoglobulin, comprising a step of contacting a sample containing the immunoglobulin with the high-loading and alkali-resistant protein A magnetic bead. The alkali-resistant protein A magnetic bead can realize rapid purification of immunoglobulin, saving about 80% of treatment time and reducing total purification costs by 50%. In addition, the alkali-resistant protein A magnetic bead has high alkali resistance. An alkaline method for in situ cleaning can be performed to regenerate the magnetic bead after use. The magnetic bead has rapid magnetic response and good dispersiveness, realizing rapid magnetic bead enrichment, cleaning, and elution.

Abstract: The present disclosure provides compositions and methods for culturing hematopoietic stem and progenitor cells, while maintaining or increasing the subpopulation of hematopoietic stem cells (HSCs). The methods and compositions describe us a 3D zwitterionic hydrogel to provide a biocompatible culture microenvironment for culturing encapsulated hematopoietic stem and progenitor cells.

Abstract: The present disclosure provides a posture detection device and a necklace, which relates to a field of automatic control, the posture detection device is worn on a body of a user, and the posture detection device includes a sensing device, a processor, and a reminding device. The sensing device is connected to the processor, and the sensing device obtains information of back posture changes of the body of the user and sends the information to the processor. The processor is connected to the reminding device, the processor processes the information, generates a reminding signal, and sends the reminding signal to the reminding device, the reminding device starts a vibration mode according to the reminding signal.

Abstract: Free-standing non-fouling polymers and polymeric compositions, monomers and macromonomers for making the polymers and polymeric compositions, objects made from the polymers and polymeric compositions, and methods for making and using the polymers and polymeric compositions.

Abstract: This application discloses a service packet forwarding method, an apparatus, and a computer storage medium. In the method, when receiving a packet sent by any second virtual resource module connected to a first SFF, the first SFF dynamically determines a forwarding path of the packet based on configuration information of a second virtual resource module for implementing a second service function, to implement dynamic load balancing on the packet instead of uniformly performing load balancing by a service function chain ingress node, so as to reduce pressure on the service function chain ingress node.

Abstract: An inclined magnetic holder comprises a magnetic base and a centrifuge tube support plate. The centrifuge tube support plate has centrifuge tube support holes. The magnetic base comprises a first bottom plate, a fixing plate, and two first-side support plates. Respective top portions of the two first-side support plates are provided with a position-locating slot. Two ends of the centrifuge tube support plate are respectively provided with a position-locating protruding block. The centrifuge tube support holes are evenly and linearly distributed on the centrifuge tube support plate. An elastic circular engagement component for holding a centrifuge tube is provided inside the centrifuge tube support holes. A block magnet is fixed to the fixing plate below and corresponding to each of the centrifuge tube support holes. A north pole or south pole surface of the block magnet faces the centrifuge tube and is parallel to an axis of the centrifuge tube.

Abstract: An automatic purification system using magnetic particles comprises: 1) a first container module; and 2) a system controller module. The first container module comprises a first container and a first magnetic field supply device disposed outside the first container. A first container liquid inlet is formed in the upper portion of the first container, and a first container liquid outlet is formed in the bottom of the first container. The system controller module can generate a variable magnetic field in the first container by controlling the first magnetic field supply device. A method for purifying a target component from a biological sample comprises a step for allowing a biological sample containing a target component to be in contact with magnetic particles capable of specifically binding the target component, in the first container in the automatic purification system.

Abstract: Embodiments of this application provide a packet forwarding method, a route sending and receiving method, and related apparatus. The method is applied to a data center in a non-uniform memory access (NUMA) architecture. The data center includes a server and a network device, and the server includes a first NUMA node and a second NUMA node. The method includes: The first interface processing unit (IPU) receives a first packet from the network device, where the first packet is a packet to be sent to the first virtual machine in the first NUMA node. The first IPU sends the first packet to the first virtual machine. The second IPU receives a second packet from the network device, where the second packet is a packet to be sent to the second virtual machine in the second NUMA node. The second IPU sends the second packet to the second virtual machine.

Abstract: The present invention relates to a large-scale magnetic purification system, including: a liquid storage apparatus, capable of being connected to a liquid source and a waste liquid barrel through a liquid path system; a stirring system mounted above the liquid storage apparatus, where a stirring paddle of the stirring system is inserted into the liquid storage apparatus for stirring; magnets mounted around the liquid storage apparatus; a magnet actuating mechanism for manipulating the magnets to move away from or close to the liquid storage apparatus; and a control system, connected to the liquid path system, the magnet actuating mechanism, and the stirring system and controlling the liquid path system, the magnet actuating mechanism, and the stirring system.