Patents by Inventor Tao Bai
Tao Bai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11577218Abstract: Provided is a high-loading and alkali-resistant protein A magnetic bead. The magnetic bead can maintain chemical stability under pH 2-14 and has an immunoglobulin G (IgG) binding capacity greater than 50 mg/mL. Further provided is a method for purifying and/or detecting an immunoglobulin, comprising a step of contacting a sample containing the immunoglobulin with the high-loading and alkali-resistant protein A magnetic bead. The alkali-resistant protein A magnetic bead can realize rapid purification of immunoglobulin, saving about 80% of treatment time and reducing total purification costs by 50%. In addition, the alkali-resistant protein A magnetic bead has high alkali resistance. An alkaline method for in situ cleaning can be performed to regenerate the magnetic bead after use. The magnetic bead has rapid magnetic response and good dispersiveness, realizing rapid magnetic bead enrichment, cleaning, and elution.Type: GrantFiled: January 4, 2018Date of Patent: February 14, 2023Assignee: Nanjing GenScript Biotech Co., Ltd.Inventors: Chao Wang, Ruina He, Weijuan Han, Hong Qian, Tao Bai
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Publication number: 20230017590Abstract: The present disclosure provides compositions and methods for culturing hematopoietic stem and progenitor cells, while maintaining or increasing the subpopulation of hematopoietic stem cells (HSCs). The methods and compositions describe us a 3D zwitterionic hydrogel to provide a biocompatible culture microenvironment for culturing encapsulated hematopoietic stem and progenitor cells.Type: ApplicationFiled: November 27, 2020Publication date: January 19, 2023Applicant: Deverra Therapeutics Inc.Inventors: Tao Bai, Devikha Chandrasekaran, Mary Prieve, Colleen Delaney
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Publication number: 20220401017Abstract: The present disclosure provides a posture detection device and a necklace, which relates to a field of automatic control, the posture detection device is worn on a body of a user, and the posture detection device includes a sensing device, a processor, and a reminding device. The sensing device is connected to the processor, and the sensing device obtains information of back posture changes of the body of the user and sends the information to the processor. The processor is connected to the reminding device, the processor processes the information, generates a reminding signal, and sends the reminding signal to the reminding device, the reminding device starts a vibration mode according to the reminding signal.Type: ApplicationFiled: June 22, 2021Publication date: December 22, 2022Inventors: ZIYU LIU, TAO BAI, KAIWEN DENG
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Patent number: 11512160Abstract: Free-standing non-fouling polymers and polymeric compositions, monomers and macromonomers for making the polymers and polymeric compositions, objects made from the polymers and polymeric compositions, and methods for making and using the polymers and polymeric compositions.Type: GrantFiled: June 2, 2016Date of Patent: November 29, 2022Assignee: University of WashingtonInventors: Shaoyi Jiang, Tao Bai, Jean-René Ella-Menye, Hsiang-Chieh Hung, Priyesh Jain, Andrew Sinclair, Harihara Subramanian Sundaram, Yang Li, Peng Zhang
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Publication number: 20220255864Abstract: This application discloses a service packet forwarding method, an apparatus, and a computer storage medium. In the method, when receiving a packet sent by any second virtual resource module connected to a first SFF, the first SFF dynamically determines a forwarding path of the packet based on configuration information of a second virtual resource module for implementing a second service function, to implement dynamic load balancing on the packet instead of uniformly performing load balancing by a service function chain ingress node, so as to reduce pressure on the service function chain ingress node.Type: ApplicationFiled: April 28, 2022Publication date: August 11, 2022Applicant: HUAWEI TECHNOLOGIES CO., LTD.Inventors: Fang WANG, Jianbin XU, Tao BAI, Yongkang ZHANG
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Patent number: 11260400Abstract: An inclined magnetic holder comprises a magnetic base and a centrifuge tube support plate. The centrifuge tube support plate has centrifuge tube support holes. The magnetic base comprises a first bottom plate, a fixing plate, and two first-side support plates. Respective top portions of the two first-side support plates are provided with a position-locating slot. Two ends of the centrifuge tube support plate are respectively provided with a position-locating protruding block. The centrifuge tube support holes are evenly and linearly distributed on the centrifuge tube support plate. An elastic circular engagement component for holding a centrifuge tube is provided inside the centrifuge tube support holes. A block magnet is fixed to the fixing plate below and corresponding to each of the centrifuge tube support holes. A north pole or south pole surface of the block magnet faces the centrifuge tube and is parallel to an axis of the centrifuge tube.Type: GrantFiled: October 30, 2018Date of Patent: March 1, 2022Assignee: Nanjing GenScript Biotech Co., Ltd.Inventors: Jinxin Zhu, Hong Qian, Weijuan Han, Ruina He, Tao Bai, Chao Wang
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Patent number: 11254906Abstract: An automatic purification system using magnetic particles comprises: 1) a first container module; and 2) a system controller module. The first container module comprises a first container and a first magnetic field supply device disposed outside the first container. A first container liquid inlet is formed in the upper portion of the first container, and a first container liquid outlet is formed in the bottom of the first container. The system controller module can generate a variable magnetic field in the first container by controlling the first magnetic field supply device. A method for purifying a target component from a biological sample comprises a step for allowing a biological sample containing a target component to be in contact with magnetic particles capable of specifically binding the target component, in the first container in the automatic purification system.Type: GrantFiled: January 4, 2018Date of Patent: February 22, 2022Assignee: Nanjing GenScript Biotech Co., Ltd.Inventors: Xin Chen, Ruina He, Chao Wang, Hong Qian, Tao Bai
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Publication number: 20220014465Abstract: Embodiments of this application provide a packet forwarding method, a route sending and receiving method, and related apparatus. The method is applied to a data center in a non-uniform memory access (NUMA) architecture. The data center includes a server and a network device, and the server includes a first NUMA node and a second NUMA node. The method includes: The first interface processing unit (IPU) receives a first packet from the network device, where the first packet is a packet to be sent to the first virtual machine in the first NUMA node. The first IPU sends the first packet to the first virtual machine. The second IPU receives a second packet from the network device, where the second packet is a packet to be sent to the second virtual machine in the second NUMA node. The second IPU sends the second packet to the second virtual machine.Type: ApplicationFiled: July 2, 2021Publication date: January 13, 2022Inventors: Fang WANG, Tao BAI, Lei FAN, Jianbin XU
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Publication number: 20210388307Abstract: The present invention relates to a large-scale magnetic purification system, including: a liquid storage apparatus, capable of being connected to a liquid source and a waste liquid barrel through a liquid path system; a stirring system mounted above the liquid storage apparatus, where a stirring paddle of the stirring system is inserted into the liquid storage apparatus for stirring; magnets mounted around the liquid storage apparatus; a magnet actuating mechanism for manipulating the magnets to move away from or close to the liquid storage apparatus; and a control system, connected to the liquid path system, the magnet actuating mechanism, and the stirring system and controlling the liquid path system, the magnet actuating mechanism, and the stirring system.Type: ApplicationFiled: October 25, 2019Publication date: December 16, 2021Applicant: Nanjing GenScript Biotech Co., Ltd.Inventors: Guodong CHEN, Zaidong FENG, Ruina HE, Hong QIAN, Tao BAI
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Publication number: 20210299677Abstract: The present invention provides a magnetic bead purification system, including: a housing; a liquid path treatment system provided inside the housing, the liquid path treatment system being connectable to a reagent barrel and a waste liquid barrel; a sample addition needle group connected to the liquid path treatment system, the sample addition needle group being movable within the housing and connected to the liquid path treatment system, so as to receive a reagent from the liquid path treatment system or to discharge a waste liquid to the liquid path treatment system; a purification magnetic separation system, including a magnetic element, the purification magnetic separation system being controllable to apply a lateral magnetic force to a purification treatment position inside the housing or stop the application of the magnetic force by the magnetic element; and a purification station system movable between a purification treatment position inside the housing and a loading position outside the housing, theType: ApplicationFiled: April 26, 2019Publication date: September 30, 2021Applicant: Nanjing GenScript Biotech Co., Ltd.Inventors: Jinxin Zhu, Ruina He, Hong Qian, Tao Bai, Deming Li, Cheng Zheng, Guodong Chen
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Patent number: 11095553Abstract: A method, an apparatus and a system for controlling routing information advertising are provided, which relate to the field of communications and are used for reducing the configuration complexity and reinforcing the operability. The method includes: receiving, by a control device, first routing information sent by a first forwarding device; wherein the first routing information includes an identifier of the first forwarding device; determining a first routing path according to the identifier of the first forwarding device, an identifier of a second forwarding device and a routing path group; and determining an advertising range of second routing information for the second forwarding device according to the first routing path; for enabling the second forwarding device to advertise the second routing information according to the advertising range of the second routing information.Type: GrantFiled: May 26, 2020Date of Patent: August 17, 2021Assignee: Huawei Technologies Co., Ltd.Inventors: Yuanbin Ouyang, Shunwan Zhuang, Fengqing Yu, Tao Bai, Lili Wang
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Publication number: 20210176080Abstract: In a method for enabling a message receive end to quickly confirm a certificate status, a defined field of a certificate includes classification information of the certificate, and a defined field of a certificate revocation list includes classification information of a revoked certificate, so that the receive end can quickly narrow a searching or matching range in massive records of the certificate revocation list based on the classification information carried in the certificate of a transmit end.Type: ApplicationFiled: February 23, 2021Publication date: June 10, 2021Inventors: Fei Li, Jintao Zhu, Chengdong He, Tao Bai
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Patent number: 11020683Abstract: A building block includes at least one of a plug portion and a socket portion. The plug portion has two cantilevered tongues deflectable toward each other. Each cantilevered tongue includes a first engaging portion. The socket portion defines a chamber and has two second engaging portions. The plug portion and the socket portion are configured in such a way that the plug portion of one building block is insertable into the chamber of the socket portion of another building block, and the two cantilevered tongues of the building block deflect toward each other after insertion of the plug portion of the building block into the chamber of the socket portion of the other building block, which allows the first engaging portions of the building block to be engaged with the second engaging portions of the other building block, thereby connecting the two building blocks together.Type: GrantFiled: December 27, 2019Date of Patent: June 1, 2021Assignee: UBTECH ROBOTICS CORP LTDInventors: Xiongyuan Fang, Youjun Xiong, Tao Bai
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Publication number: 20210086096Abstract: A building block includes at least one of a plug portion and a socket portion. The plug portion has two cantilevered tongues deflectable toward each other. Each cantilevered tongue includes a first engaging portion. The socket portion defines a chamber and has two second engaging portions. The plug portion and the socket portion are configured in such a way that the plug portion of one building block is insertable into the chamber of the socket portion of another building block, and the two cantilevered tongues of the building block deflect toward each other after insertion of the plug portion of the building block into the chamber of the socket portion of the other building block, which allows the first engaging portions of the building block to be engaged with the second engaging portions of the other building block, thereby connecting the two building blocks together.Type: ApplicationFiled: December 27, 2019Publication date: March 25, 2021Inventors: XIONGYUAN FANG, Youjun Xiong, Tao Bai
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Publication number: 20210069726Abstract: An inclined magnetic holder is disclosed, comprising a magnetic base and a centrifuge tube support plate. The centrifuge tube support plate is provided with centrifuge tube support holes. The magnetic base comprises a first bottom plate, a fixing plate provided on the first bottom plate, and two first-side support plates respectively provided at two sides of the fixing plate. Respective top portions of the two first-side support plates are provided with a position-locating slot. A bottom surface of the position-locating slot is configured with an inclined angle. Two ends of the centrifuge tube support plate are respectively provided with a position-locating protruding block for fitting and assembling into the position-locating slot. The centrifuge tube support holes are evenly and linearly distributed on the centrifuge tube support plate. An elastic circular engagement component for holding a centrifuge tube is provided inside the centrifuge tube support holes.Type: ApplicationFiled: October 30, 2018Publication date: March 11, 2021Applicant: Nanjingjinsirui Science & Technology Biology Corp.Inventors: Jinxin Zhu, Hong Qian, Weijuan Han, Ruina He, Tao Bai, Chao Wang
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Patent number: 10828398Abstract: Functionalized zwitterionic and mixed charge polymers and copolymers, methods for making the polymers and copolymers, hydrogels prepared from the functionalized zwitterionic and mixed charge polymers and copolymers, methods for making and using the hydrogels, and zwitterionic and mixed charge polymers and copolymers for administration for therapeutic agents.Type: GrantFiled: April 29, 2019Date of Patent: November 10, 2020Assignee: University of WashingtonInventors: Shaoyi Jiang, Tao Bai, Harihara Subramanian Sundaram, Andrew William Sinclair, Jean-René Ella-Menye, Priyesh Jain
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Publication number: 20200289712Abstract: Functionalized zwitterionic and mixed charge polymers and copolymers, methods for making the polymers and copolymers, hydrogels prepared from the functionalized zwitterionic and mixed charge polymers and copolymers, methods for making and using the hydrogels, and zwitterionic and mixed charge polymers and copolymers for administration for therapeutic agents.Type: ApplicationFiled: April 29, 2019Publication date: September 17, 2020Applicant: University of WashingtonInventors: Shaoyi Jiang, Tao Bai, Harihara Subramanian Sundaram, Andrew William Sinclair, Jean-René Ella-Menye, Priyesh Jain
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Publication number: 20200287820Abstract: A method, an apparatus and a system for controlling routing information advertising are provided, which relate to the field of communications and are used for reducing the configuration complexity and reinforcing the operability. The method includes: receiving, by a control device, first routing information sent by a first forwarding device; wherein the first routing information includes an identifier of the first forwarding device; determining a first routing path according to the identifier of the first forwarding device, an identifier of a second forwarding device and a routing path group; and determining an advertising range of second routing information for the second forwarding device according to the first routing path; for enabling the second forwarding device to advertise the second routing information according to the advertising range of the second routing information.Type: ApplicationFiled: May 26, 2020Publication date: September 10, 2020Inventors: Yuanbin OUYANG, Shunwan ZHUANG, Fengqing YU, Tao BAI, Lili WANG
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Publication number: 20200253192Abstract: Zwitterionic microgels, zwitterionic microgel assemblies, their formulations and methods for their use.Type: ApplicationFiled: July 20, 2017Publication date: August 13, 2020Applicant: University of WashingtonInventors: Shaoyi Jiang, Andrew Sinclair, Mary Elizabeth O'Kelly, Tao Bai, Priyesh Jain
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Patent number: 10693768Abstract: A method, an apparatus and a system for controlling routing information advertising are provided, which relate to the field of communications and are used for reducing the configuration complexity and reinforcing the operability. The method includes: receiving, by a control device, first routing information sent by a first forwarding device; wherein the first routing information includes an identifier of the first forwarding device; determining a first routing path according to the identifier of the first forwarding device, an identifier of a second forwarding device and a routing path group; and determining an advertising range of second routing information for the second forwarding device according to the first routing path; for enabling the second forwarding device to advertise the second routing information according to the advertising range of the second routing information.Type: GrantFiled: December 21, 2018Date of Patent: June 23, 2020Assignee: Huawei Technologies Co., Ltd.Inventors: Yuanbin Ouyang, Shunwan Zhuang, Fengqing Yu, Tao Bai, Lili Wang