Abstract: Techniques described herein relate to mobile computing device technologies, such as systems, methods, apparatuses, and computer-readable media for tracking an object from a plurality of objects. In one aspect, the plurality of objects may be similar. Techniques discussed herein propose dynamically learning information associated with each of the objects and discriminating between objects based on their differentiating features. In one implementation, this may be done by maintaining a database associated with each object and updating the dynamic database transferred while the objects are tracked. The tracker uses algorithmic means for differentiating objects by focusing on the differences amongst the objects. For example, in one implementation, the method may weigh the differences between different fingers higher than their associated similarities to facilitate differentiating the fingers.

Abstract: The invention provides novel compounds having the general formula: and pharmaceutically acceptable salts thereof, wherein the variables RA, subscript n, ring A, X2, L, subscript m, X1, B, R1, R2, R3, R4, R5 and RN have the meaning as described herein, and compositions containing such compounds and methods for using such compounds and compositions.

Abstract: Ion channel modulating compounds are disclosed. The compounds of the present invention may be incorporated in compositions and kits. The present invention also discloses a variety of in vitro and in vivo uses for the compounds and compositions, including the treatment of arrhythmia and the production of analgesia and local anesthesia.

Abstract: An adaptive security apparatus is arranged for updating a security parameter in a database. The adaptive security apparatus includes a message receiver, a data processor, a security processor, and an adaptive parameter processor. The message receiver is arranged for receiving a message. The data processor is arranged for receiving the message from the message receiver and a security parameter from the database. The security processor is arranged for performing a deciphering process and a decoding process according to an output of the data processor. The adaptive parameter processor is arranged for updating the security parameter. Besides, an adaptive security method arranged for adaptively updating a security parameter includes: checking a status of a deciphering process and accordingly generating a checking result; and referring to the checking result to adaptively search a target pattern of the security parameter from a plurality of candidate patterns.

Abstract: The present disclosure provides a cover sheet for a microarray reaction device. In one aspect, the present cover sheet or device ensures the reaction units/volumes are stable and/or consistent among assay samples and assay runs, allowing samples (e.g., reaction solutions) to be conveniently added and distributed uniformly.

Abstract: Methods for the preparation of stereoisomerically substantially aminocyclohexyl ether compounds such as trans-(1R,2R)-aminocyclohexyl ether compounds and/or trans-(1S,2S)-aminocyclohexyl ether compounds as well as various intermediates and substrates are disclosed.

Abstract: A rate control method of perceptual-based rate-distortion (R-D) optimized bit allocation is disclosed. An input frame is firstly determined as a key frame or non-key frame. A key frame is additionally encoded to generate rate-distortion (R-D) points. The R-D model of each basic unit (BU) is updated, followed by perceptual-based bit allocation, thereby generating a target bit rate. A quantization parameter (QP) is computed according to the target bit rate, and the current BU is encoded according to the QP. A rate-quantization (R-Q) model is updated if not all BUs have been encoded.

Abstract: The invention provides novel compounds having the general formula: and pharmaceutically acceptable salts thereof, wherein the variables RA, subscript n, ring A, X2, L, subscript m, X1, B, R1, R2, R3, R4, R5 and RN have the meaning as described herein, and compositions containing such compounds and methods for using such compounds and compositions.

Abstract: This disclosure presents methods, systems, computer-readable media, and apparatuses for optically tracking the location of one or more objects. The techniques may involve accumulation of initial image data, establishment of a dataset library containing image features, and tracking using a plurality of modules or trackers, for example an optical flow module, decision forest module, and color tracking module. Tracking outputs from the optical flow, decision forest and/or color tracking modules are synthesized to provide a final tracking output. The dataset library may be updated in the process.

Abstract: The present invention is directed to a rate-distortion optimized (RDO) transform and quantization system. A frame classification unit classifies an input frame as either a key frame or a non-key frame. A rate model update unit generates at least one model parameter of a rate model according to a transform coefficient and a bitrate resulted from an encoded key frame. An RDO transform and quantization unit processes the input frame, thereby generating a quantized transform coefficient according to the model parameter. A frame buffer is used to store a previous frame, according to which the bitrate is estimated.

Abstract: Methods for the preparation of stereoisomerically substantially aminocyclohexyl ether compounds such as trans-(1R,2R)-aminocyclohexyl ether compounds and/or trans-(1S,2S)-aminocyclohexyl ether compounds as well as various intermediates and substrates are disclosed.

Abstract: The present invention discloses a component in the hedgehog signaling pathway that can be useful in the treatment and diagnosis of hedgehog signaling pathway associated disorders. In this regard, the present invention discloses that RanBPM regulated the stability of hedgehog signaling molecule, smoothened (SMO) and that inactivation of RanBPM by siRNA prevented growth and metastasis of cancer cells.

Abstract: A perceptual-based video coding method provides a perceptual-based rate-distortion (R-D) curve as a predictive R-D curve. The Lagrange multiplier for a current frame is then determined by deciding a slope, with sign reversed, of a tangent to the predictive R-D curve at a current point that is on the predictive R-D curve and closest to a previous R-D point of a previous encoded frame. The current frame is then encoded according to the determined Lagrange multiplier.

Abstract: Aminocyclohexyl ether compounds are disclosed. The compounds of the present invention may be incorporated in compositions and kits. The present invention also discloses uses for the compounds and compositions, including the treatment of arrhythmia.

Abstract: A rate control method of perceptual-based rate-distortion (R-D) optimized bit allocation is disclosed. An input frame is firstly determined as a key frame or non-key frame. A key frame is additionally encoded to generate rate-distortion (R-D) points. The R-D model of each basic unit (BU) is updated, followed by perceptual-based bit allocation, thereby generating a target bit rate. A quantization parameter (QP) is computed according to the target bit rate, and the current BU is encoded according to the QP. A rate-quantization (R-Q) model is updated if not all BUs have been encoded.

Abstract: The present application relates to methods and compositions for the generation of therapeutic cells having reduced incidence of karyotypic abnormalities. In several embodiments cardiac stem cells are cultured in an antioxidant-supplemented media that reduces levels of reactive oxygen species, but does not down regulate DNA repair mechanisms. In several embodiments, physiological oxygen concentrations are used during culture in order to increase the proliferation of stem cells, decrease the senescence of the cells, decrease genomic instability, and/or augment the functionality of such cells for cellular therapies.

Abstract: The present application relates to methods and compositions for the generation of therapeutic cells having reduced incidence of karyotypic abnormalities. In several embodiments cardiac stem cells are cultured in an antioxidant-supplemented media that reduces levels of reactive oxygen species, but does not down regulate DNA repair mechanisms. In several embodiments, physiological oxygen concentrations are used during culture in order to increase the proliferation of stem cells, decrease the senescence of the cells, decrease genomic instability, and/or augment the functionality of such cells for cellular therapies.

Abstract: Ion channel modulating compounds are disclosed. The compounds of the present invention may be incorporated in compositions and kits. The present invention also discloses a variety of in vitro and in vivo uses for the compounds and compositions, including the treatment of arrhythmia and the production of analgesia and local anesthesia.

Abstract: Ion channel modulating compounds are disclosed. The compounds of the present invention may be incorporated in compositions and kits. The present invention also discloses a variety of in vitro and in vivo uses for the compounds and compositions, including the treatment of arrhythmia and the production of analgesia and local anesthesia.

Abstract: A perceptual-based video coding method provides a perceptual-based rate-distortion (R-D) curve as a predictive R-D curve. The Lagrange multiplier for a current frame is then determined by deciding a slope, with sign reversed, of a tangent to the predictive R-D curve at a current point that is on the predictive R-D curve and closest to a previous R-D point of a previous encoded frame. The current frame is then encoded according to the determined Lagrange multiplier.