Abstract: Compounds, compositions and methods are provided for modulating the activity of EP2 and EP4 receptors, and for the treatment, prevention and amelioration of one or more symptoms of diseases or disorders related to the activity of EP2 and EP4 receptors. In certain embodiments, the compounds are antagonists of both the EP2 and EP4 receptors.

Abstract: The invention provides compounds having the general formula (I): and pharmaceutically acceptable salts thereof, wherein the variables RA, RAA, n, ring A, X2, L, m, R1, R2, R3, R4, R5, and RN have the meaning as described herein, and compositions containing such compounds and methods for using such compounds and compositions.

Abstract: An electronic device has a photosensitive element, a charge storage element, and a node. The photosensitive element generates a current in response to illumination thereon. The charge storage element is coupled to the photosensitive element and is used to store charge in response to the current generated by the photosensitive element. The signal reading circuit is coupled to the photosensitive element, and the node is coupled between the photosensitive element and the charge storage element. The charge storage element and the photosensitive element are coupled in series, and the node is coupled to an end of the signal reading circuit.

Abstract: An example electronic device includes: an audio and video (AV) processor, a computer subsystem, a control mechanism, and a media playing device. The AV processor includes an AV input port to receive external AV signals from an external media source. The computer subsystem is to provide internal AV signals to the AV processor. The control mechanism is to control the AV processor to select between the external AV signals and the internal AV signals, and enable the AV processor to transmit selected AV signals to the media playing device. The media playing device is to play the selected AV signals.

Abstract: An electronic device includes a touch sensing layer, a touch sensor, a biometric sensor and a driver. The touch sensor is used to identify a touch location and output a touch signal upon the touch sensing layer being touched. The biometric sensor includes a plurality of sensing blocks, and is used to generate electrical signals corresponding to biometric data. The driver is coupled to the touch sensor and the biometric sensor, and is used to drive a portion of the plurality of sensing blocks according to the touch signal.

Abstract: An electronic device includes a photodiode, a first transistor, a second transistor, a third transistor and a capacitor. The photodiode has a first terminal and a second terminal. The first transistor has a control terminal used to receive a reset signal, a first terminal coupled to the second terminal of the photodiode, and a second terminal. The second transistor has a control terminal coupled to the second terminal of the photodiode, a first terminal and a second terminal. The third transistor has a control terminal used to receive a row selection signal, a first terminal coupled to the second terminal of the second transistor, and a second terminal. The capacitor has a first terminal coupled to the second terminal of the photodiode, and a second terminal coupled to the second terminal of the first transistor.

Abstract: An electronic device includes a reset circuit and a first image sensing circuit. The reset circuit has a first node used to receive a reset signal, and a second node. The first image sensing circuit is coupled to the reset circuit and includes a photodiode, a first transistor and a second transistor. The photodiode has a first terminal coupled to the second node, and a second terminal. The first transistor has a control terminal coupled to the second terminal of the photodiode via a third node, a first terminal and a second terminal. The second transistor has a control terminal configured to receive a row selection signal and a first terminal coupled to the second terminal of the first transistor.

Abstract: The present invention provides an analyzer for predicting a prognosis of cancer radiotherapy, including a detection device and an arithmetic device. In a specimen, expression levels of a plurality of microRNAs (miRNAs) can be detected by the detection device. The miRNAs includes hsa-miR-130a-3p, hsa-miR-215-5p, hsa-miR-29a-3p, hsa-let-7b-5p, hsa-miR-19b-3p, hsa-miR-374a-5p and hsa-miR-148a-3p. The expression levels of miRNAs can be analyzed by the arithmetic device using logistic regression, and the analyzed values can be used to determine that the prognosis of cancer radiotherapy is poor or good.

Abstract: This invention is directed to novel aliphatic prolinamide derivatives of Formula I, and pharmaceutically acceptable salts, solvates, solvates of the salt and prodrugs thereof, useful in the prevention (e.g., delaying the onset of or reducing the risk of developing) and treatment (e.g., controlling, alleviating, or slowing the progression of) of age-related macular degeneration (AMD) and related diseases of the eye. These diseases include dry-AMD, wet-AMD, geographic atrophy, diabetic retinopathy, retinopathy of prematurity, polypoidal choroidal vasculopathy, and degeneration of retinal or photoreceptor cells. The invention disclosed herein is further directed to methods of prevention, slowing the progress of, and treatment of dry-AMD, wet-AMD, and geographic atrophy, diabetic retinopathy, retinopathy of prematurity, polypoidal choroidal vasculopathy, and degeneration of retinal or photoreceptor cells, comprising: administration of a therapeutically effective amount of compound of the invention.

Abstract: The invention provides compounds having the general formula I: and pharmaceutically acceptable salts thereof, wherein the variables RA, RAA, subscript n, ring A, X2, L, subscript m, X1, R1, R2, R3, R4, R5, and RN have the meaning as described herein, and compositions containing such compounds and methods for using such compounds and compositions.

Abstract: In an example, an audio, video, and voice communication (AVC) processor includes an audio and video (AV) port to receive audio and video (AV) signals and an audio and voice input/output (I/O) port to communicate with a voice transceiver. The control unit, coupled to the AVC processor, controls the AVC processor to select the received signals and enables the AVC processor to transmit the selected signals to a media and voice playing unit.

Abstract: This invention is directed to novel aliphatic prolinamide derivatives of Formula I, and pharmaceutically acceptable salts, solvates, solvates of the salt and prodrugs thereof, useful in the prevention (e.g., delaying the onset of or reducing the risk of developing) and treatment (e.g., controlling, alleviating, or slowing the progression of) of age-related macular degeneration (AMD) and related diseases of the eye. These diseases include dry-AMD, wet-AMD, geographic atrophy, diabetic retinopathy, retinopathy of prematurity, polypoidal choroidal vasculopathy, and degeneration of retinal or photoreceptor cells. The invention disclosed herein is further directed to methods of prevention, slowing the progress of, and treatment of dry-AMD, wet-AMD, and geographic atrophy, diabetic retinopathy, retinopathy of prematurity, polypoidal choroidal vasculopathy, and degeneration of retinal or photoreceptor cells, comprising: administration of a therapeutically effective amount of compound of the invention.

Abstract: Compounds, compositions and methods are provided for modulating the activity of EP2 and EP4 receptors, and for the treatment, prevention and amelioration of one or more symptoms of diseases or disorders related to the activity of EP2 and EP4 receptors. In certain embodiments, the compounds are antagonists of both the EP2 and EP4 receptors.

Abstract: Provided herein are methods, devices, and systems of wireless communication. In one embodiment, a method for wireless communication between a first electronic device and a second electronic device includes: providing information symbols to the first electronic device, transmitting a pairing request from the first electronic device to the second electronic device, obtaining a pairing password by accessing a database, and establishing a wireless communication channel between the first electronic device and the second electronic device. In some embodiments, the information symbols are provided audibly or visually by the second electronic device and include a wireless communication address of the second electronic device. In some embodiments, the pairing password is obtained using the wireless communication address. In some embodiments, the wireless communication channel is obtained using the obtained pairing password.

Abstract: A semiconductor structure is disclosed. The semiconductor structure includes: a substrate; a first passivation layer over the substrate; a second passivation layer over the first passivation layer; a magnetic layer in the second passivation layer; and an etch stop layer between the magnetic layer and the first passivation layer, wherein the etch stop layer includes at least one acid resistant layer, and the acid resistant layer includes a metal oxide. A method for manufacturing a semiconductor structure is also disclosed.

Abstract: A semiconductor structure is disclosed. The semiconductor structure includes: a substrate; a first passivation layer over the substrate; a second passivation layer over the first passivation layer; a magnetic layer in the second passivation layer; and an etch stop layer between the magnetic layer and the first passivation layer, wherein the etch stop layer includes at least one acid resistant layer, and the acid resistant layer includes a metal oxide. A method for manufacturing a semiconductor structure is also disclosed.

Abstract: The invention provides compounds having the general formula (I): and pharmaceutically acceptable salts thereof, wherein the variables RA, RAA, n, ring A, X2, L, m, R1, R2, R3, R4, R5, and RN have the meaning as described herein, and compositions containing such compounds and methods for using such compounds and compositions.

Abstract: Techniques for associating environmental information with fingerprint images for fingerprint enrollment and matching are presented. The techniques may include capturing, using a fingerprint sensor of a mobile device, one or more images of a fingerprint. The techniques may include analyzing the one or more images to obtain fingerprint information associated with the fingerprint. The techniques may include obtaining, via an orientation sensor of the mobile device, environmental information indicating an orientation of the mobile device associated with the capturing of the one or more images. The techniques may additionally include generating, using the fingerprint information, an enrollment template for the fingerprint. The techniques may include associating the enrollment template with the environmental information.

Abstract: Systems and methods for biometric authentication are disclosed. The invention may be used to authenticate an individual. At least two enrollment templates may be obtained at different times. Later, an inquiry template may be obtained and compared to each of the enrollment templates in separate and distinct comparison operations. The match scores arising from the comparison operations may be fused to provide a composite match score. The composite match score may be compared to an acceptance range. If the composite match score is within the acceptance range, the individual may be authenticated.

Abstract: The present disclosure provides a cover sheet for a microarray reaction device. In one aspect, the present cover sheet or device ensures the reaction units/volumes are stable and/or consistent among assay samples and assay runs, allowing samples (e.g., reaction solutions) to be conveniently added and distributed uniformly.