Abstract: The present invention relates to compounds of Formula (I): and to their pharmaceutical compositions, and to their methods of use. These compounds provide a treatment for myeloproliferative disorders and cancer.

Abstract: Reframing circuitry controls communications between a physical layer device and a link layer device. In a first direction of communication, the reframing circuitry receives a container frame with the container frame having a first arrangement of columns, and outputs a virtual container frame that includes a modified version of the container frame received by the reframing circuitry, with the modified version of the container frame having a second arrangement of columns different than the first arrangement of columns. For example, the reframing circuitry in generating the modified version of the container frame may remove a path overhead column of the container frame and replace that path overhead column with a stuff column in the modified version of the container frame. The virtual container frame may be configured to include the path overhead column that was removed from the container frame in generating the modified version of the container frame.

Abstract: This invention provides for prodrug Compounds I, pharmaceutical compositions thereof, and their use in treating HIV infection. wherein: X is C or N with the proviso that when X is N, R1 does not exist; W is C or N with the proviso that when W is N, R2 does not exist; V is C; E is hydrogen or a pharmaceutically acceptable salt thereof; and Y is selected from the group consisting of Also, this invention provides for intermediate Compounds II useful in making prodrug Compounds I. wherein: L and M are independently selected from the group consisting of C1-C6 alkyl, phenyl, benzyl, trialkylsilyl, -2,2,2-trichloroethoxy and 2-trimethylsilylethoxy.

Abstract: A drug-delivery chip and a method of fabricating the same are provided. The drug-delivery chip has a main body having at least one drug receiving space individually formed with an opening for storing drugs therein; a thin film for sealing up the at least one drug receiving space; a first conductive wire connecting to one end of the thin film; a second conductive wire connecting to another end of the thin film; a signal-receiving module for receiving actuated signals; and a control module for applying voltages to first and second wire conductive s according to the actuated signal, thereby generating heat to break off the thin film for the release of a drug or drugs received in the at least one drug receiving space.

Abstract: A Coriolis mass flow meter (1) which has at least two curved measurement tubes (2), at least one actuator arrangement, at least one sensor arrangement and comprising at least one housing structure (5), the measurement tubes (2) being connected at their inlet end portion and an outlet end portion with at least a first oscillation node plate (3) and a second oscillation node plate (4). The flow meter achieves increased measurement accuracy and a reduced susceptibility to perturbing oscillations by at least one of the oscillation node plates being connected at the inlet end and the outlet end of the housing structure (5). A third oscillation node plate (6) can be additionally arranged on the inlet end portion and the outlet end portion of the tubes, the third oscillation node plate being connected to the housing structure.

Abstract: A computer enclosure includes a shell body, and an expansion card retention assembly. The shell body includes a main chassis, and a side wall perpendicular to the main chassis. The side wall defines an elongated through hole extending along a first direction perpendicular to the main chassis. The expansion card retention assembly includes a first and second expansion frames fixed on the side wall. The first expansion frame includes a main board with a length in the first direction less than that of the through hole, and is configured for fixing a first expansion card. The second expansion frame includes an elongated main plate extending along the first direction, and a first support platform perpendicularly extending from an end of the main plate. The main plate and the first support platform are configured for matingly engaging with an expansion card bracket of a second expansion card.

Abstract: Methods and devices for detecting single-event transients in combinational logic circuits and other circuits. A sensing circuit detects a voltage or current deviation at a bulk contact node of a transistor. Output of the sensing circuit is amplified and used to flip a latch. Output of the latch may be evaluated and used in possible error correction measures.

Abstract: Compounds having drug and bio-affecting properties are described herein, including their properties, pharmaceutical compositions and methods of use. In particular, tricyclic aryl or heteroaryl piperazine diamide derivatives that possess unique antiviral activity are set forth. These compounds are useful for the treatment of HIV and AIDS.

Abstract: A spectra shaping apparatus for chirped pulse amplification (CPA): uses a spectrum decomposing system with CTSI construction, a spectrum synthesizing system with CTSI structure that is optically symmetrical to the decomposing structure, and a spectrum shaping system including an aperture and a planar reflector for spectrum shaping function design. The apparatus accomplishes the following functions: firstly decomposing the spectrum of a chirped temporal pulse laser to a spectral domain; then shaping the spectrum in the spectral domain; finally synthesizing un-shiftily this shaped spectrum in the spectral domain into a temporal chirped pulse with a designed shape. The apparatus has the feature of fabricating easy, compacting the structure, requiring less space, and cheap in cost etc.

Abstract: Phthalide derivatives and the use of which to manufacture the sensitizer or reverser of the antineoplastic agent are described. The phthalide derivatives can enhance the sensitivity of drug-resistance tumor cells against chemotherapy and decrease the drug-resistance of tumor cells 5-30 folder and enhance notably several chemotherapy agents-induced apoptosis of tumor cells.

Abstract: The disclosure provides compounds of formula I, including pharmaceutically acceptable salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV.

Abstract: A rotating cylinder includes a cylinder body, a piston, a piston shaft assembly, a main body and a guiding assembly. The cylinder body defines a receiving chamber. The piston, the piston shaft assembly, the main body and the guiding assembly are received in the receiving chamber. The piston shaft assembly is fixed to the piston, and defines at least one guiding groove lengthwise thereof. Each guiding groove includes a spiral portion and an extending portion. The main shaft is non-rotatably connected to the piston shaft assembly away from the piston and exposed out of the cylinder body. The guiding assembly sleeves on the piston shaft assembly and is slidably connected with the at least one guiding groove. The main shaft is driven to rotate when the guiding assembly engages the spiral portion, and move lengthwise when the guiding assembly is slidably connected with the extending portion.

Abstract: A micro inertial measurement system includes a housing, a sensing module, and a damper. The sensing module includes a rigid sensing support, a measuring and controlling circuit board mounted on the rigid sensing support and an inertial sensor set on the measuring and controlling circuit board. The inertial sensor includes a gyroscope and an accelerometer. The sensing module is mounted in the housing. The damper is mounted in the housing and set in the gap between the sensing module and the inside wall of the housing. By use of the above-mentioned structure, the noise immunity of the inertial measuring system can be greatly improved, and the volume and weight of the inertial measuring system can be greatly reduced.

Abstract: A conveying device includes a housing, a linear driving mechanism, a first sliding assembly, a second sliding assembly, and a carrying mechanism. The linear driving mechanism is assembled within the housing. The first sliding assembly is slidably assembled together with the second sliding assembly within the housing, and both sliding assemblies are driven by the linear driving mechanism to slide horizontally. The carrying mechanism is slidably sandwiched between the first sliding assembly and the second sliding assembly. The first sliding assembly and the second sliding assembly are driven by the linear driving mechanism to slide within the housing along either a same direction or along opposite directions. The carrying mechanism may slide linearly together with the first sliding assembly and the second sliding assembly, or slide upwards and downwards perpendicular to the linear sliding direction of the first sliding assembly and the second sliding assembly.

Abstract: A method and apparatus for user information processing in a network environment. The method performs an orthogonal transform on first and second vectors representing information related to first and second users respectively to obtain first and second transformed vectors. Then, the method splits the first and second transformed vectors into two parts respectively, such that first and second vectors cannot be derived from the first or second parts. The first and second user devices exchange the first part of the first transformed vector and the second part of the second transformed vector. The first and second user devices calculate the inner product of the first parts and the second parts respectively. Finally, the two inner products of the parts are summed to get an inner product of the first and second vectors. Also provided are a method and system for resource recommendation in a network environment.

Abstract: A compound of Formula I, including pharmaceutically acceptable salts thereof: wherein A is selected from the group of:

Abstract: The present invention provides a method of wet etching a silicon slice including a silicon substrate and a metal film layer thereon comprising steps of: performing lithographic process to the silicon slice forming a masked silicon slice comprising the silicon substrate and a partially masked metal film thereon; immersing the masked silicon slice into an etchant; rotating the masked silicon slice in the etchant; injecting high-purity nitrogen gas into the etchant for agitating the etchant; removing the masked silicon slice out of the etchant, upon completion of etching; and rinsing the masked silicon slice with deionized water.

Abstract: A method is provided for the automatic discovery and updating of gateway peers within a WiMAX Access Service Network in order to control R4 intra-ASN mobility. In a preferred embodiment, When a WiMAX Access Service Network Gateway is added to the network, it propagates an AUTO-DISCOVER message using the Open Shortest Path First protocol's opaque Link State Advertisement. The received messages are used to establish connections to the sending peer based on data packaged in the Link State Advertisement. Once a connection has been established, UPDATE and CONFIRM messages are used by Access Service Network Gateways to exchange WiMAX R4 routing information. The message sequence number is used to correspond UPDATE and CONFIRM messages. The OSPF-based keep-alive mechanism is used to determine whether internal peers are reachable.

Abstract: A self-collimator planar spectroscopy shaping device for chirped pulse amplification (CPA): uses a spectrum decomposing system with CTSI construction, a spectrum synthesizing system with CTSI structure that is symmetrical to the decomposing structure, and a spectrum shaping system including an aperture and a planar reflector for spectrum shaping function design. The device accomplishes the following functions: firstly decomposing the spectrum of a chirped temporal pulse laser to a spectral domain; then shaping the spectrum in the spectral domain; finally synthesizing un-shiftily this shaped spectrum in the spectral domain into a temporal chirped pulse with a designed shape.

Abstract: The disclosure provides compounds of formula I, including pharmaceutically acceptable salts, as well as compositions and methods of using the compounds. The compounds have activity against hepatitis C virus (HCV) and may be useful in treating those infected with HCV.